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Items: 49

1.

Targeting PCSK9 as a promising new mechanism for lowering low-density lipoprotein cholesterol.

Della Badia LA, Elshourbagy NA, Mousa SA.

Pharmacol Ther. 2016 Aug;164:183-94. doi: 10.1016/j.pharmthera.2016.04.011. Epub 2016 Apr 29. Review.

PMID:
27133571
2.

Cholesterol: the good, the bad, and the ugly - therapeutic targets for the treatment of dyslipidemia.

Elshourbagy NA, Meyers HV, Abdel-Meguid SS.

Med Princ Pract. 2014;23(2):99-111. doi: 10.1159/000356856. Epub 2013 Dec 11. Review.

3.

Cloning and pharmacological characterization of the cat urotensin-II receptor (UT).

Aiyar N, Johns DG, Ao Z, Disa J, Behm DJ, Foley JJ, Buckley PT, Sarau HM, van-der-Keyl HK, Elshourbagy NA, Douglas SA.

Biochem Pharmacol. 2005 Apr 1;69(7):1069-79.

PMID:
15763543
4.

Radioligand binding and functional characterization of recombinant human NmU1 and NmU2 receptors stably expressed in clonal human embryonic kidney-293 cells.

Aiyar N, Disa J, Foley JJ, Buckley PT, Wixted WE, Pullen M, Shabon U, Dul E, Szekeres PG, Elshourbagy NA, Sarau HM, Appelbaum E, Bolaky J.

Pharmacology. 2004 Sep;72(1):33-41.

PMID:
15292653
5.

Characterization of CC-chemokine receptor 7 expression on murine T cells in lymphoid tissues.

Bjorkdahl O, Barber KA, Brett SJ, Daly MG, Plumpton C, Elshourbagy NA, Tite JP, Thomsen LL.

Immunology. 2003 Oct;110(2):170-9.

6.

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.

Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls HR Jr, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI.

J Biol Chem. 2003 Mar 28;278(13):11303-11. Epub 2002 Dec 19.

7.

Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.

Elshourbagy NA, Douglas SA, Shabon U, Harrison S, Duddy G, Sechler JL, Ao Z, Maleeff BE, Naselsky D, Disa J, Aiyar NV.

Br J Pharmacol. 2002 May;136(1):9-22.

8.

AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.

Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC.

J Biol Chem. 2001 Aug 3;276(31):28969-75. Epub 2001 May 31.

9.

Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor.

Sarau HM, Feild JA, Ames RS, Foley JJ, Nuthulaganti P, Schmidt DB, Buckley PT, Elshourbagy NA, Brawner ME, Luttmann MA, Giardina GA, Hay DW.

Eur J Pharmacol. 2001 Feb 16;413(2-3):143-50.

PMID:
11226387
10.

The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.

Wood MD, Murkitt KL, Rice SQ, Testa T, Punia PK, Stammers M, Jenkins O, Elshourbagy NA, Shabon U, Taylor SJ, Gager TL, Minton J, Hirst WD, Price GW, Pangalos M.

Br J Pharmacol. 2000 Nov;131(6):1050-4.

11.

Identification of an EDG7 variant, HOFNH30, a G-protein-coupled receptor for lysophosphatidic acid.

Fitzgerald LR, Dytko GM, Sarau HM, Mannan IJ, Ellis C, Lane PA, Tan KB, Murdock PR, Wilson S, Bergsma DJ, Ames RS, Foley JJ, Campbell DA, McMillan L, Evans N, Elshourbagy NA, Minehart H, Tsui P.

Biochem Biophys Res Commun. 2000 Jul 14;273(3):805-10.

PMID:
10891327
12.

Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.

Elshourbagy NA, Ames RS, Fitzgerald LR, Foley JJ, Chambers JK, Szekeres PG, Evans NA, Schmidt DB, Buckley PT, Dytko GM, Murdock PR, Milligan G, Groarke DA, Tan KB, Shabon U, Nuthulaganti P, Wang DY, Wilson S, Bergsma DJ, Sarau HM.

J Biol Chem. 2000 Aug 25;275(34):25965-71.

13.

Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3.

Szekeres PG, Muir AI, Spinage LD, Miller JE, Butler SI, Smith A, Rennie GI, Murdock PR, Fitzgerald LR, Wu Hl, McMillan LJ, Guerrera S, Vawter L, Elshourbagy NA, Mooney JL, Bergsma DJ, Wilson S, Chambers JK.

J Biol Chem. 2000 Jul 7;275(27):20247-50.

14.

Molecular characterization of a human scavenger receptor, human MARCO.

Elshourbagy NA, Li X, Terrett J, Vanhorn S, Gross MS, Adamou JE, Anderson KM, Webb CL, Lysko PG.

Eur J Biochem. 2000 Feb;267(3):919-26.

15.

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.

Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW, Ao Z, Disa J, Holmes SD, Stadel JM, Martin JD, Liu WS, Glover GI, Wilson S, McNulty DE, Ellis CE, Elshourbagy NA, Shabon U, Trill JJ, Hay DW, Ohlstein EH, Bergsma DJ, Douglas SA.

Nature. 1999 Sep 16;401(6750):282-6. Erratum in: Nature 1999 Dec 23-30;402(6764):898.

PMID:
10499587
16.

Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR.

Smart D, Jerman JC, Brough SJ, Rushton SL, Murdock PR, Jewitt F, Elshourbagy NA, Ellis CE, Middlemiss DN, Brown F.

Br J Pharmacol. 1999 Sep;128(1):1-3.

17.

Identification of a small-molecule, nonpeptide macrophage scavenger receptor antagonist.

Lysko PG, Weinstock J, Webb CL, Brawner ME, Elshourbagy NA.

J Pharmacol Exp Ther. 1999 Jun;289(3):1277-85.

PMID:
10336517
18.

Molecular cloning and characterization of the porcine calcitonin gene-related peptide receptor.

Elshourbagy NA, Adamou JE, Swift AM, Disa J, Mao J, Ganguly S, Bergsma DJ, Aiyar N.

Endocrinology. 1998 Apr;139(4):1678-83.

PMID:
9528949
19.

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richarson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Mar 6;92(5):1 page following 696. No abstract available.

20.

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Feb 20;92(4):573-85.

21.

Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils.

White JR, Imburgia C, Dul E, Appelbaum E, O'Donnell K, O'Shannessy DJ, Brawner M, Fornwald J, Adamou J, Elshourbagy NA, Kaiser K, Foley JJ, Schmidt DB, Johanson K, Macphee C, Moores K, McNulty D, Scott GF, Schleimer RP, Sarau HM.

J Leukoc Biol. 1997 Nov;62(5):667-75.

PMID:
9365122
22.

Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist.

Sarau HM, Griswold DE, Potts W, Foley JJ, Schmidt DB, Webb EF, Martin LD, Brawner ME, Elshourbagy NA, Medhurst AD, Giardina GA, Hay DW.

J Pharmacol Exp Ther. 1997 Jun;281(3):1303-11.

PMID:
9190866
23.

Adenosine triphosphate citrate lyase mediates hypocitraturia in rats.

Melnick JZ, Srere PA, Elshourbagy NA, Moe OW, Preisig PA, Alpern RJ.

J Clin Invest. 1996 Nov 15;98(10):2381-7.

24.

Molecular characterization of a novel human endothelin receptor splice variant.

Elshourbagy NA, Adamou JE, Gagnon AW, Wu HL, Pullen M, Nambi P.

J Biol Chem. 1996 Oct 11;271(41):25300-7.

25.

A cDNA encoding the calcitonin gene-related peptide type 1 receptor.

Aiyar N, Rand K, Elshourbagy NA, Zeng Z, Adamou JE, Bergsma DJ, Li Y.

J Biol Chem. 1996 May 10;271(19):11325-9.

26.

Developmental expression of endothelin receptors in cerebellar neurons differentiating in culture.

Lysko PG, Elshourbagy NA, Pullen M, Nambi P.

Brain Res Dev Brain Res. 1995 Aug 28;88(1):96-101.

PMID:
7493411
27.

Cloning and functional characterization of the human vasoactive intestinal peptide (VIP)-2 receptor.

Adamou JE, Aiyar N, Van Horn S, Elshourbagy NA.

Biochem Biophys Res Commun. 1995 Apr 17;209(2):385-92.

PMID:
7733904
28.

1,3-Diarylindan-2-carboxylic acids, potent and selective non-peptide endothelin receptor antagonists.

Elliott JD, Lago MA, Cousins RD, Gao A, Leber JD, Erhard KF, Nambi P, Elshourbagy NA, Kumar C, Lee JA, et al.

J Med Chem. 1994 May 27;37(11):1553-7. No abstract available.

PMID:
8201588
29.

Molecular cloning and functional characterization of a human liver vasoactive intestinal peptide receptor.

Gagnon AW, Aiyar N, Elshourbagy NA.

Cell Signal. 1994 Mar;6(3):321-33.

PMID:
7917790
30.

Molecular characterization and regulation of the human endothelin receptors.

Elshourbagy NA, Korman DR, Wu HL, Sylvester DR, Lee JA, Nuthalaganti P, Bergsma DJ, Kumar CS, Nambi P.

J Biol Chem. 1993 Feb 25;268(6):3873-9.

31.

Cloning and expression of a human ATP-citrate lyase cDNA.

Elshourbagy NA, Near JC, Kmetz PJ, Wells TN, Groot PH, Saxty BA, Hughes SA, Franklin M, Gloger IS.

Eur J Biochem. 1992 Mar 1;204(2):491-9.

32.

Molecular cloning and characterization of the major endothelin receptor subtype in porcine cerebellum.

Elshourbagy NA, Lee JA, Korman DR, Nuthalaganti P, Sylvester DR, Dilella AG, Sutiphong JA, Kumar CS.

Mol Pharmacol. 1992 Mar;41(3):465-73.

PMID:
1312214
33.

Nucleotide sequence of endothelin cDNA from bovine endothelial cells.

Elshourbagy NA, Kmetz P, Sathe GM.

Nucleic Acids Res. 1990 Jul 25;18(14):4273. No abstract available.

34.

Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age.

Elshourbagy NA, Near JC, Kmetz PJ, Sathe GM, Southan C, Strickler JE, Gross M, Young JF, Wells TN, Groot PH.

J Biol Chem. 1990 Jan 25;265(3):1430-5.

35.

Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene.

Lauer SJ, Walker D, Elshourbagy NA, Reardon CA, Levy-Wilson B, Taylor JM.

J Biol Chem. 1988 May 25;263(15):7277-86.

36.

Structure and expression of the human apolipoprotein A-IV gene.

Elshourbagy NA, Walker DW, Paik YK, Boguski MS, Freeman M, Gordon JI, Taylor JM.

J Biol Chem. 1987 Jun 15;262(17):7973-81.

37.

On computer-assisted analysis of biological sequences: proline punctuation, consensus sequences, and apolipoprotein repeats.

Boguski MS, Freeman M, Elshourbagy NA, Taylor JM, Gordon JI.

J Lipid Res. 1986 Oct;27(10):1011-34. Review.

38.

Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E.

Boguski MS, Birkenmeier EH, Elshourbagy NA, Taylor JM, Gordon JI.

J Biol Chem. 1986 May 15;261(14):6398-407.

39.
40.

Rat apolipoprotein A-IV: application of computational methods for studying the structure, function, and evolution of a protein.

Boguski MS, Elshourbagy NA, Taylor JM, Gordon JI.

Methods Enzymol. 1986;128:753-73.

PMID:
3088393
41.

Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and insulin.

Elshourbagy NA, Boguski MS, Liao WS, Jefferson LS, Gordon JI, Taylor JM.

Proc Natl Acad Sci U S A. 1985 Dec;82(23):8242-6.

42.

Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins.

Lowe JB, Boguski MS, Sweetser DA, Elshourbagy NA, Taylor JM, Gordon JI.

J Biol Chem. 1985 Mar 25;260(6):3413-7.

43.
44.

Human apolipoprotein E mRNA. cDNA cloning and nucleotide sequencing of a new variant.

McLean JW, Elshourbagy NA, Chang DJ, Mahley RW, Taylor JM.

J Biol Chem. 1984 May 25;259(10):6498-504.

45.

Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents.

Heuman DM, Gallagher EJ, Barwick JL, Elshourbagy NA, Guzelian PS.

Mol Pharmacol. 1982 May;21(3):753-60. No abstract available.

PMID:
6810090
46.
47.
48.
49.

Induction of hepatic heme oxygenase activity by bromobenzene.

Guzelian PS, Elshourbagy NA.

Arch Biochem Biophys. 1979 Aug;196(1):178-85. No abstract available.

PMID:
507802

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