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Items: 22

1.

Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated Streptomyces.

Wang X, Elshahawi SI, Ponomareva LV, Ye Q, Liu Y, Copley GC, Hower JC, Hatcher BE, Kharel MK, Van Lanen SG, She QB, Voss SR, Thorson JS, Shaaban KA.

J Nat Prod. 2019 Dec 27;82(12):3469-3476. doi: 10.1021/acs.jnatprod.9b01015. Epub 2019 Dec 13.

PMID:
31833370
2.

Baraphenazines A-G, Divergent Fused Phenazine-Based Metabolites from a Himalayan Streptomyces.

Wang X, Abbas M, Zhang Y, Elshahawi SI, Ponomareva LV, Cui Z, Van Lanen SG, Sajid I, Voss SR, Shaaban KA, Thorson JS.

J Nat Prod. 2019 Jun 28;82(6):1686-1693. doi: 10.1021/acs.jnatprod.9b00289. Epub 2019 May 22.

PMID:
31117525
3.

Puromycins B-E, Naturally Occurring Amino-Nucleosides Produced by the Himalayan Isolate Streptomyces sp. PU-14G.

Abbas M, Elshahawi SI, Wang X, Ponomareva LV, Sajid I, Shaaban KA, Thorson JS.

J Nat Prod. 2018 Nov 26;81(11):2560-2566. doi: 10.1021/acs.jnatprod.8b00720. Epub 2018 Nov 12.

4.

Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2.

Wang X, Elshahawi SI, Cai W, Zhang Y, Ponomareva LV, Chen X, Copley GC, Hower JC, Zhan CG, Parkin S, Rohr J, Van Lanen SG, Shaaban KA, Thorson JS.

J Nat Prod. 2017 Apr 28;80(4):1141-1149. doi: 10.1021/acs.jnatprod.7b00108. Epub 2017 Mar 30.

5.

Structure and specificity of a permissive bacterial C-prenyltransferase.

Elshahawi SI, Cao H, Shaaban KA, Ponomareva LV, Subramanian T, Farman ML, Spielmann HP, Phillips GN Jr, Thorson JS, Singh S.

Nat Chem Biol. 2017 Apr;13(4):366-368. doi: 10.1038/nchembio.2285. Epub 2017 Feb 6.

6.

Mccrearamycins A-D, Geldanamycin-Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe.

Wang X, Zhang Y, Ponomareva LV, Qiu Q, Woodcock R, Elshahawi SI, Chen X, Zhou Z, Hatcher BE, Hower JC, Zhan CG, Parkin S, Kharel MK, Voss SR, Shaaban KA, Thorson JS.

Angew Chem Int Ed Engl. 2017 Mar 6;56(11):2994-2998. doi: 10.1002/anie.201612447. Epub 2017 Jan 31.

7.

Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning.

Zhang J, Hughes RR, Saunders MA, Elshahawi SI, Ponomareva LV, Zhang Y, Winchester SR, Scott SA, Sunkara M, Morris AJ, Prendergast MA, Shaaban KA, Thorson JS.

J Nat Prod. 2017 Jan 27;80(1):12-18. doi: 10.1021/acs.jnatprod.6b00949. Epub 2016 Dec 28.

8.

Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6.

Shaaban KA, Saunders MA, Zhang Y, Tran T, Elshahawi SI, Ponomareva LV, Wang X, Zhang J, Copley GC, Sunkara M, Kharel MK, Morris AJ, Hower JC, Tremblay MS, Prendergast MA, Thorson JS.

J Nat Prod. 2017 Jan 27;80(1):2-11. doi: 10.1021/acs.jnatprod.6b00948. Epub 2016 Dec 28.

9.

Antibacterial and Cytotoxic Actinomycins Y6-Y9 and Zp from Streptomyces sp. Strain Gö-GS12.

Cai W, Wang X, Elshahawi SI, Ponomareva LV, Liu X, McErlean MR, Cui Z, Arlinghaus AL, Thorson JS, Van Lanen SG.

J Nat Prod. 2016 Oct 28;79(10):2731-2739. Epub 2016 Oct 13.

10.

Correction to "Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8".

Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, Thorson JS.

Org Lett. 2015 Nov 6;17(21):5515. doi: 10.1021/acs.orglett.5b02788. Epub 2015 Oct 12. No abstract available.

PMID:
26458135
11.

Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691.

Shaaban KA, Elshahawi SI, Wang X, Horn J, Kharel MK, Leggas M, Thorson JS.

J Nat Prod. 2015 Jul 24;78(7):1723-9. doi: 10.1021/acs.jnatprod.5b00429. Epub 2015 Jun 19.

12.

Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8.

Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, Thorson JS.

Org Lett. 2015 Jun 5;17(11):2796-9. doi: 10.1021/acs.orglett.5b01203. Epub 2015 May 11. Erratum in: Org Lett. 2015 Nov 6;17(21):5515.

13.

A comprehensive review of glycosylated bacterial natural products.

Elshahawi SI, Shaaban KA, Kharel MK, Thorson JS.

Chem Soc Rev. 2015 Nov 7;44(21):7591-697. doi: 10.1039/c4cs00426d. Review.

14.

Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19.

Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, Kennedy MA, Bingman CA, Zhu H, Phillips GN Jr, Thorson JS.

ACS Chem Biol. 2014 Oct 17;9(10):2347-58. doi: 10.1021/cb500327m. Epub 2014 Aug 13.

15.

Mullinamides A and B, new cyclopeptides produced by the Ruth Mullins coal mine fire isolate Streptomyces sp. RM-27-46.

Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS.

J Antibiot (Tokyo). 2014 Aug;67(8):571-5. doi: 10.1038/ja.2014.37. Epub 2014 Apr 9.

16.

Ruthmycin, a new tetracyclic polyketide from Streptomyces sp. RM-4-15.

Wang X, Elshahawi SI, Shaaban KA, Fang L, Ponomareva LV, Zhang Y, Copley GC, Hower JC, Zhan CG, Kharel MK, Thorson JS.

Org Lett. 2014 Jan 17;16(2):456-9. doi: 10.1021/ol4033418. Epub 2013 Dec 16.

17.

Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2.

Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS.

J Antibiot (Tokyo). 2014 Mar;67(3):223-30. doi: 10.1038/ja.2013.113. Epub 2013 Nov 13.

18.

The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6.

Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS.

Nat Prod Res. 2014;28(5):337-9. doi: 10.1080/14786419.2013.855932. Epub 2013 Nov 18.

19.

Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15.

Shaaban KA, Wang X, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS.

J Nat Prod. 2013 Sep 27;76(9):1619-26. doi: 10.1021/np400308w. Epub 2013 Aug 15.

20.

Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15.

Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Zhang Y, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS.

J Nat Prod. 2013 Aug 23;76(8):1441-7. doi: 10.1021/np400231r. Epub 2013 Aug 14.

21.

Boronated tartrolon antibiotic produced by symbiotic cellulose-degrading bacteria in shipworm gills.

Elshahawi SI, Trindade-Silva AE, Hanora A, Han AW, Flores MS, Vizzoni V, Schrago CG, Soares CA, Concepcion GP, Distel DL, Schmidt EW, Haygood MG.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):E295-304. doi: 10.1073/pnas.1213892110. Epub 2013 Jan 3.

22.

Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis.

Donia MS, Fricke WF, Partensky F, Cox J, Elshahawi SI, White JR, Phillippy AM, Schatz MC, Piel J, Haygood MG, Ravel J, Schmidt EW.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):E1423-32. doi: 10.1073/pnas.1111712108. Epub 2011 Nov 28.

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