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Items: 15

1.

Direct screening of enzyme activity using infrared matrix-assisted laser desorption electrospray ionization.

Nazari M, Ekelöf M, Khodjaniyazova S, Elsen NL, Williams JD, Muddiman DC.

Rapid Commun Mass Spectrom. 2017 Nov 30;31(22):1868-1874. doi: 10.1002/rcm.7971.

2.

Insights into activity and inhibition from the crystal structure of human O-GlcNAcase.

Elsen NL, Patel SB, Ford RE, Hall DL, Hess F, Kandula H, Kornienko M, Reid J, Selnick H, Shipman JM, Sharma S, Lumb KJ, Soisson SM, Klein DJ.

Nat Chem Biol. 2017 Jun;13(6):613-615. doi: 10.1038/nchembio.2357. Epub 2017 Mar 27.

PMID:
28346407
3.

Integration of Affinity Selection-Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway.

Kutilek VD, Andrews CL, Richards MP, Xu Z, Sun T, Chen Y, Hashke A, Smotrov N, Fernandez R, Nickbarg EB, Chamberlin C, Sauvagnat B, Curran PJ, Boinay R, Saradjian P, Allen SJ, Byrne N, Elsen NL, Ford RE, Hall DL, Kornienko M, Rickert KW, Sharma S, Shipman JM, Lumb KJ, Coleman K, Dandliker PJ, Kariv I, Beutel B.

J Biomol Screen. 2016 Jul;21(6):608-19. doi: 10.1177/1087057116637353. Epub 2016 Mar 11.

PMID:
26969322
4.

Dissecting Therapeutic Resistance to ERK Inhibition.

Jha S, Morris EJ, Hruza A, Mansueto MS, Schroeder GK, Arbanas J, McMasters D, Restaino CR, Dayananth P, Black S, Elsen NL, Mannarino A, Cooper A, Fawell S, Zawel L, Jayaraman L, Samatar AA.

Mol Cancer Ther. 2016 Apr;15(4):548-59. doi: 10.1158/1535-7163.MCT-15-0172. Epub 2016 Feb 1.

5.

Structural basis for biomolecular recognition in overlapping binding sites in a diiron enzyme system.

Acheson JF, Bailey LJ, Elsen NL, Fox BG.

Nat Commun. 2014 Sep 24;5:5009. doi: 10.1038/ncomms6009.

6.

Cell-free translation of biofuel enzymes.

Takasuka TE, Walker JA, Bergeman LF, Vander Meulen KA, Makino S, Elsen NL, Fox BG.

Methods Mol Biol. 2014;1118:71-95. doi: 10.1007/978-1-62703-782-2_5.

7.

Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity.

Elsen NL, Lu J, Parthasarathy G, Reid JC, Sharma S, Soisson SM, Lumb KJ.

J Am Chem Soc. 2012 Aug 1;134(30):12342-5. doi: 10.1021/ja303564a. Epub 2012 Jul 20.

PMID:
22793495
8.

Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics.

Tan CM, Therien AG, Lu J, Lee SH, Caron A, Gill CJ, Lebeau-Jacob C, Benton-Perdomo L, Monteiro JM, Pereira PM, Elsen NL, Wu J, Deschamps K, Petcu M, Wong S, Daigneault E, Kramer S, Liang L, Maxwell E, Claveau D, Vaillancourt J, Skorey K, Tam J, Wang H, Meredith TC, Sillaots S, Wang-Jarantow L, Ramtohul Y, Langlois E, Landry F, Reid JC, Parthasarathy G, Sharma S, Baryshnikova A, Lumb KJ, Pinho MG, Soisson SM, Roemer T.

Sci Transl Med. 2012 Mar 21;4(126):126ra35. doi: 10.1126/scitranslmed.3003592.

9.

Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase.

Bailey LJ, Acheson JF, McCoy JG, Elsen NL, Phillips GN Jr, Fox BG.

Biochemistry. 2012 Feb 14;51(6):1101-13. doi: 10.1021/bi2018333. Epub 2012 Feb 2.

PMID:
22264099
10.

Structure of cellobiose phosphorylase from Clostridium thermocellum in complex with phosphate.

Bianchetti CM, Elsen NL, Fox BG, Phillips GN Jr.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1345-9. doi: 10.1107/S1744309111032660. Epub 2011 Oct 25.

11.

Global gene expression patterns in Clostridium thermocellum as determined by microarray analysis of chemostat cultures on cellulose or cellobiose.

Riederer A, Takasuka TE, Makino S, Stevenson DM, Bukhman YV, Elsen NL, Fox BG.

Appl Environ Microbiol. 2011 Feb;77(4):1243-53. doi: 10.1128/AEM.02008-10. Epub 2010 Dec 17.

12.

Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase.

Elsen NL, Bailey LJ, Hauser AD, Fox BG.

Biochemistry. 2009 May 12;48(18):3838-46. doi: 10.1021/bi900144a.

PMID:
19290655
13.

X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus.

Levin EJ, Elsen NL, Seder KD, McCoy JG, Fox BG, Phillips GN Jr.

Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):933-40. doi: 10.1107/S0907444908021653. Epub 2008 Aug 13.

14.

Soluble expression and purification of the oxidoreductase component of toluene 4-monooxygenase.

Bailey LJ, Elsen NL, Pierce BS, Fox BG.

Protein Expr Purif. 2008 Jan;57(1):9-16. Epub 2007 Sep 19.

15.

Redox and functional analysis of the Rieske ferredoxin component of the toluene 4-monooxygenase.

Elsen NL, Moe LA, McMartin LA, Fox BG.

Biochemistry. 2007 Jan 30;46(4):976-86.

PMID:
17240981

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