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Items: 1 to 50 of 72

1.

Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias.

Mandelboum S, Manber Z, Elroy-Stein O, Elkon R.

PLoS Biol. 2019 Nov 12;17(11):e3000481. doi: 10.1371/journal.pbio.3000481. eCollection 2019 Nov.

2.

eIF2B Mutations Cause Mitochondrial Malfunction in Oligodendrocytes.

Herrero M, Mandelboum S, Elroy-Stein O.

Neuromolecular Med. 2019 Sep;21(3):303-313. doi: 10.1007/s12017-019-08551-9. Epub 2019 May 27.

PMID:
31134486
3.

Drug Screening Identifies Sigma-1-Receptor as a Target for the Therapy of VWM Leukodystrophy.

Atzmon A, Herrero M, Sharet-Eshed R, Gilad Y, Senderowitz H, Elroy-Stein O.

Front Mol Neurosci. 2018 Sep 18;11:336. doi: 10.3389/fnmol.2018.00336. eCollection 2018.

4.

A Unique ISR Program Determines Cellular Responses to Chronic Stress.

Guan BJ, van Hoef V, Jobava R, Elroy-Stein O, Valasek LS, Cargnello M, Gao XH, Krokowski D, Merrick WC, Kimball SR, Komar AA, Koromilas AE, Wynshaw-Boris A, Topisirovic I, Larsson O, Hatzoglou M.

Mol Cell. 2017 Dec 7;68(5):885-900.e6. doi: 10.1016/j.molcel.2017.11.007.

5.

Mitochondrial malfunction in vanishing white matter disease: a disease of the cytosolic translation machinery.

Elroy-Stein O.

Neural Regen Res. 2017 Oct;12(10):1610-1612. doi: 10.4103/1673-5374.217329. No abstract available.

6.

Proteomic analysis of polyribosomes identifies splicing factors as potential regulators of translation during mitosis.

Aviner R, Hofmann S, Elman T, Shenoy A, Geiger T, Elkon R, Ehrlich M, Elroy-Stein O.

Nucleic Acids Res. 2017 Jun 2;45(10):5945-5957. doi: 10.1093/nar/gkx326.

7.

Mutant eIF2B leads to impaired mitochondrial oxidative phosphorylation in vanishing white matter disease.

Raini G, Sharet R, Herrero M, Atzmon A, Shenoy A, Geiger T, Elroy-Stein O.

J Neurochem. 2017 Jun;141(5):694-707. doi: 10.1111/jnc.14024. Epub 2017 Apr 16.

8.

Uncovering Hidden Layers of Cell Cycle Regulation through Integrative Multi-omic Analysis.

Aviner R, Shenoy A, Elroy-Stein O, Geiger T.

PLoS Genet. 2015 Oct 6;11(10):e1005554. doi: 10.1371/journal.pgen.1005554. eCollection 2015 Oct.

9.

Proteomics-level analysis of myelin formation and regeneration in a mouse model for Vanishing White Matter disease.

Gat-Viks I, Geiger T, Barbi M, Raini G, Elroy-Stein O.

J Neurochem. 2015 Aug;134(3):513-26. doi: 10.1111/jnc.13142. Epub 2015 May 14.

10.

Genome-wide identification and quantification of protein synthesis in cultured cells and whole tissues by puromycin-associated nascent chain proteomics (PUNCH-P).

Aviner R, Geiger T, Elroy-Stein O.

Nat Protoc. 2014 Apr;9(4):751-60. doi: 10.1038/nprot.2014.051. Epub 2014 Mar 6.

PMID:
24603934
11.

Dicodon monitoring of protein synthesis (DiCoMPS) reveals levels of synthesis of a viral protein in single cells.

Barhoom S, Farrell I, Shai B, Dahary D, Cooperman BS, Smilansky Z, Elroy-Stein O, Ehrlich M.

Nucleic Acids Res. 2013 Oct;41(18):e177. doi: 10.1093/nar/gkt686. Epub 2013 Aug 21.

12.

Novel proteomic approach (PUNCH-P) reveals cell cycle-specific fluctuations in mRNA translation.

Aviner R, Geiger T, Elroy-Stein O.

Genes Dev. 2013 Aug 15;27(16):1834-44. doi: 10.1101/gad.219105.113. Epub 2013 Aug 9.

13.

PUNCH-P for global translatome profiling: Methodology, insights and comparison to other techniques.

Aviner R, Geiger T, Elroy-Stein O.

Translation (Austin). 2013 Dec 18;1(2):e27516. doi: 10.4161/trla.27516. eCollection 2013.

14.

Poor cerebral inflammatory response in eIF2B knock-in mice: implications for the aetiology of vanishing white matter disease.

Cabilly Y, Barbi M, Geva M, Marom L, Chetrit D, Ehrlich M, Elroy-Stein O.

PLoS One. 2012;7(10):e46715. doi: 10.1371/journal.pone.0046715. Epub 2012 Oct 4.

15.

A point mutation in translation initiation factor eIF2B leads to function--and time-specific changes in brain gene expression.

Marom L, Ulitsky I, Cabilly Y, Shamir R, Elroy-Stein O.

PLoS One. 2011;6(10):e26992. doi: 10.1371/journal.pone.0026992. Epub 2011 Oct 31.

16.

Quantitative single cell monitoring of protein synthesis at subcellular resolution using fluorescently labeled tRNA.

Barhoom S, Kaur J, Cooperman BS, Smorodinsky NI, Smilansky Z, Ehrlich M, Elroy-Stein O.

Nucleic Acids Res. 2011 Oct;39(19):e129. doi: 10.1093/nar/gkr601. Epub 2011 Jul 27.

17.

Mitotic modulation of translation elongation factor 1 leads to hindered tRNA delivery to ribosomes.

Sivan G, Aviner R, Elroy-Stein O.

J Biol Chem. 2011 Aug 12;286(32):27927-35. doi: 10.1074/jbc.M111.255810. Epub 2011 Jun 10.

18.

Species-specific microRNA roles elucidated following astrocyte activation.

Mor E, Cabilly Y, Goldshmit Y, Zalts H, Modai S, Edry L, Elroy-Stein O, Shomron N.

Nucleic Acids Res. 2011 May;39(9):3710-23. doi: 10.1093/nar/gkq1325. Epub 2011 Jan 18.

19.

Evaluation of the endoplasmic reticulum-stress response in eIF2B-mutated lymphocytes and lymphoblasts from CACH/VWM patients.

Horzinski L, Kantor L, Huyghe A, Schiffmann R, Elroy-Stein O, Boespflug-Tanguy O, Fogli A.

BMC Neurol. 2010 Oct 19;10:94. doi: 10.1186/1471-2377-10-94.

20.

A mouse model for eukaryotic translation initiation factor 2B-leucodystrophy reveals abnormal development of brain white matter.

Geva M, Cabilly Y, Assaf Y, Mindroul N, Marom L, Raini G, Pinchasi D, Elroy-Stein O.

Brain. 2010 Aug;133(Pt 8):2448-61. doi: 10.1093/brain/awq180.

PMID:
20826436
21.

Translational control of protein kinase Ceta by two upstream open reading frames.

Raveh-Amit H, Maissel A, Poller J, Marom L, Elroy-Stein O, Shapira M, Livneh E.

Mol Cell Biol. 2009 Nov;29(22):6140-8. doi: 10.1128/MCB.01044-09. Epub 2009 Sep 21.

22.

Diverse poly(A) binding proteins mediate internal translational initiation by a plant viral IRES.

Marom L, Hen-Avivi S, Pinchasi D, Chekanova JA, Belostotsky DA, Elroy-Stein O.

RNA Biol. 2009 Sep-Oct;6(4):446-54. Epub 2009 Sep 7.

PMID:
19502818
23.

A point mutation in translation initiation factor 2B leads to a continuous hyper stress state in oligodendroglial-derived cells.

Kantor L, Pinchasi D, Mintz M, Hathout Y, Vanderver A, Elroy-Stein O.

PLoS One. 2008;3(11):e3783. doi: 10.1371/journal.pone.0003783. Epub 2008 Nov 21.

24.

DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis.

Marash L, Liberman N, Henis-Korenblit S, Sivan G, Reem E, Elroy-Stein O, Kimchi A.

Mol Cell. 2008 May 23;30(4):447-59. doi: 10.1016/j.molcel.2008.03.018. Epub 2008 May 1.

25.

Gene expression using the vaccinia virus/ T7 RNA polymerase hybrid system.

Elroy-Stein O, Moss B.

Curr Protoc Protein Sci. 2001 May;Chapter 5:Unit5.15. doi: 10.1002/0471140864.ps0515s14.

PMID:
18429181
26.

Gene expression using the vaccinia virus/T7 RNA polymerase hybrid system.

Elroy-Stein O, Moss B.

Curr Protoc Mol Biol. 2001 May;Chapter 16:Unit16.19. doi: 10.1002/0471142727.mb1619s43.

PMID:
18265126
27.

Regulation of mRNA Translation during cellular division.

Sivan G, Elroy-Stein O.

Cell Cycle. 2008 Mar 15;7(6):741-4. Epub 2008 Jan 8. Review.

PMID:
18239464
28.

Ribosomal slowdown mediates translational arrest during cellular division.

Sivan G, Kedersha N, Elroy-Stein O.

Mol Cell Biol. 2007 Oct;27(19):6639-46. Epub 2007 Jul 30.

29.

Effect of Ku proteins on IRES-mediated translation.

Silvera D, Koloteva-Levine N, Burma S, Elroy-Stein O.

Biol Cell. 2006 Jun;98(6):353-61.

PMID:
16448389
30.
31.

Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients.

Kantor L, Harding HP, Ron D, Schiffmann R, Kaneski CR, Kimball SR, Elroy-Stein O.

Hum Genet. 2005 Oct;118(1):99-106. Epub 2005 Oct 28.

PMID:
16041584
32.

Naturally occurring antisense: transcriptional leakage or real overlap?

Dahary D, Elroy-Stein O, Sorek R.

Genome Res. 2005 Mar;15(3):364-8. Epub 2005 Feb 14.

33.
34.

Interaction of hnRNP-C1/C2 proteins with RNA: analysis using the yeast three-hybrid system.

Koloteva-Levine N, Amichay M, Elroy-Stein O.

FEBS Lett. 2002 Jul 17;523(1-3):73-8.

35.
36.

New ways of initiating translation in eukaryotes.

Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M Jr, Gehrke L, Goldman E, Groner Y, Harford JB, Hatzglou M, He B, Hellen CU, Hentze MW, Hershey J, Hershey P, Hohn T, Holcik M, Hunter CP, Igarashi K, Jackson R, Jagus R, Jefferson LS, Joshi B, Kaempfer R, Katze M, Kaufman RJ, Kiledjian M, Kimball SR, Kimchi A, Kirkegaard K, Koromilas AE, Krug RM, Kruys V, Lamphear BJ, Lemon S, Lloyd RE, Maquat LE, Martinez-Salas E, Mathews MB, Mauro VP, Miyamoto S, Mohr I, Morris DR, Moss EG, Nakashima N, Palmenberg A, Parkin NT, Pe'ery T, Pelletier J, Peltz S, Pestova TV, Pilipenko EV, Prats AC, Racaniello V, Read GS, Rhoads RE, Richter JD, Rivera-Pomar R, Rouault T, Sachs A, Sarnow P, Scheper GC, Schiff L, Schoenberg DR, Semler BL, Siddiqui A, Skern T, Sonenberg N, Sossin W, Standart N, Tahara SM, Thomas AA, Toulmé JJ, Wilusz J, Wimmer E, Witherell G, Wormington M.

Mol Cell Biol. 2001 Dec;21(23):8238-46. No abstract available.

37.

Transcription-coupled translation control of AML1/RUNX1 is mediated by cap- and internal ribosome entry site-dependent mechanisms.

Pozner A, Goldenberg D, Negreanu V, Le SY, Elroy-Stein O, Levanon D, Groner Y.

Mol Cell Biol. 2000 Apr;20(7):2297-307.

38.

The use of bi-cistronic transfer vectors for the baculovirus expression system.

Finkelstein Y, Faktor O, Elroy-Stein O, Levi BZ.

J Biotechnol. 1999 Sep 24;75(1):33-44.

PMID:
10510857
40.
41.

Does EBV RNA modulate ADA mRNA translation?

Gerlitz G, Elroy-Stein O.

Leukemia. 1998 Feb;12(2):249. No abstract available.

42.

Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression.

Savitsky K, Platzer M, Uziel T, Gilad S, Sartiel A, Rosenthal A, Elroy-Stein O, Shiloh Y, Rotman G.

Nucleic Acids Res. 1997 May 1;25(9):1678-84.

43.

PDGF2/c-sis mRNA leader contains a differentiation-linked internal ribosomal entry site (D-IRES).

Bernstein J, Sella O, Le SY, Elroy-Stein O.

J Biol Chem. 1997 Apr 4;272(14):9356-62.

44.

Adenovirus E1a interferes with expression of vaccinia viral genes.

Strauss D, Elroy-Stein O, Ehrlich R.

Gene. 1997 Jan 15;184(2):279-84.

PMID:
9031640
45.

The glucocerebrosidase D409H mutation in Gaucher disease.

Pasmanik-Chor M, Laadan S, Elroy-Stein O, Zimran A, Abrahamov A, Gatt S, Horowitz M.

Biochem Mol Med. 1996 Dec;59(2):125-33.

PMID:
8986634
46.

Overexpression of human glucocerebrosidase containing different-sized leaders.

Pasmanik-Chor M, Elroy-Stein O, Aerts H, Agmon V, Gatt S, Horowitz M.

Biochem J. 1996 Jul 1;317 ( Pt 1):81-8.

47.

Cleavage of the HIV replication primer tRNALys,3 in human cells expressing bacterial anticodon nuclease.

Shterman N, Elroy-Stein O, Morad I, Amitsur M, Kaufmann G.

Nucleic Acids Res. 1995 May 25;23(10):1744-9.

48.
49.

Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules.

Zrihan-Licht S, Baruch A, Elroy-Stein O, Keydar I, Wreschner DH.

FEBS Lett. 1994 Dec 12;356(1):130-6.

50.

Characterization and molecular cloning of a novel MUC1 protein, devoid of tandem repeats, expressed in human breast cancer tissue.

Zrihan-Licht S, Vos HL, Baruch A, Elroy-Stein O, Sagiv D, Keydar I, Hilkens J, Wreschner DH.

Eur J Biochem. 1994 Sep 1;224(2):787-95.

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