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Items: 6


c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.

Fu L, Lin YD, Elrod HA, Yue P, Oh Y, Li B, Tao H, Chen GZ, Shin DM, Khuri FR, Sun SY.

Mol Cancer. 2010 Dec 20;9:315. doi: 10.1186/1476-4598-9-315.


Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impact.

Elrod HA, Fan S, Muller S, Chen GZ, Pan L, Tighiouart M, Shin DM, Khuri FR, Sun SY.

PLoS One. 2010 Aug 16;5(8):e12178. doi: 10.1371/journal.pone.0012178.


Celecoxib antagonizes perifosine's anticancer activity involving a cyclooxygenase-2-dependent mechanism.

Elrod HA, Yue P, Khuri FR, Sun SY.

Mol Cancer Ther. 2009 Sep;8(9):2575-85. doi: 10.1158/1535-7163.MCT-09-0390. Epub 2009 Sep 15.


PPARgamma and Apoptosis in Cancer.

Elrod HA, Sun SY.

PPAR Res. 2008;2008:704165. doi: 10.1155/2008/704165.


Modulation of death receptors by cancer therapeutic agents.

Elrod HA, Sun SY.

Cancer Biol Ther. 2008 Feb;7(2):163-73. Epub 2007 Nov 21. Review.


The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.

Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.

Mol Cancer Ther. 2007 Jul;6(7):2029-38. Epub 2007 Jun 29.

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