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Items: 12

1.

Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.

Elphick LM, Pawolleck N, Guschina IA, Chaieb L, Eikel D, Nau H, Harwood JL, Plant NJ, Williams RS.

Dis Model Mech. 2012 Mar;5(2):231-40. doi: 10.1242/dmm.008391. Epub 2011 Oct 14.

2.

The chemoselective one-step alkylation and isolation of thiophosphorylated cdk2 substrates in the presence of native cysteine.

Lee SE, Elphick LM, Kramer HB, Jones AM, Child ES, Anderson AA, Bonnac L, Suwaki N, Kessler BM, Gouverneur V, Mann DJ.

Chembiochem. 2011 Mar 7;12(4):633-40. doi: 10.1002/cbic.201000528. Epub 2011 Feb 8.

PMID:
21305681
3.

Cyclin D1 and cyclin D3 show divergent responses to distinct mitogenic stimulation.

Anderson AA, Child ES, Prasad A, Elphick LM, Mann DJ.

J Cell Physiol. 2010 Nov;225(3):638-45. doi: 10.1002/jcp.22207.

PMID:
20458731
4.

Dose-dependent changes in cyclin D1 in response to 4-nitroquinoline 1-oxide-induced DNA damage.

Suwaki N, Child ES, Elphick LM, Mann DJ.

Arch Biochem Biophys. 2010 May;497(1-2):55-61. doi: 10.1016/j.abb.2010.03.003. Epub 2010 Mar 7.

PMID:
20214871
5.

Synthesis and O-phosphorylation of 3,3,4,4-tetrafluoroaryl-C-nucleoside analogues.

Bonnac L, Lee SE, Giuffredi GT, Elphick LM, Anderson AA, Child ES, Mann DJ, Gouverneur V.

Org Biomol Chem. 2010 Mar 21;8(6):1445-54. doi: 10.1039/b922442d. Epub 2010 Jan 25.

PMID:
20204220
6.

Exploring the roles of protein kinases using chemical genetics.

Elphick LM, Lee SE, Anderson AA, Child ES, Bonnac L, Gouverneur V, Mann DJ.

Future Med Chem. 2009 Oct;1(7):1233-41. doi: 10.4155/fmc.09.50.

PMID:
21426100
7.

A quantitative comparison of wild-type and gatekeeper mutant cdk2 for chemical genetic studies with ATP analogues.

Elphick LM, Lee SE, Child ES, Prasad A, Pignocchi C, Thibaudeau S, Anderson AA, Bonnac L, Gouverneur V, Mann DJ.

Chembiochem. 2009 Jun 15;10(9):1519-26. doi: 10.1002/cbic.200900052.

PMID:
19437469
8.

Synthesis and reactivity of novel gamma-phosphate modified ATP analogues.

Lee SE, Elphick LM, Anderson AA, Bonnac L, Child ES, Mann DJ, Gouverneur V.

Bioorg Med Chem Lett. 2009 Jul 15;19(14):3804-7. doi: 10.1016/j.bmcl.2009.04.028. Epub 2009 Apr 14.

PMID:
19410453
9.

Opposing roles for caspase and calpain death proteases in L-glutamate-induced oxidative neurotoxicity.

Elphick LM, Hawat M, Toms NJ, Meinander A, Mikhailov A, Eriksson JE, Kass GE.

Toxicol Appl Pharmacol. 2008 Oct 15;232(2):258-67. doi: 10.1016/j.taap.2008.07.008. Epub 2008 Jul 19.

PMID:
18687350
10.
11.

Using chemical genetics and ATP analogues to dissect protein kinase function.

Elphick LM, Lee SE, Gouverneur V, Mann DJ.

ACS Chem Biol. 2007 May 22;2(5):299-314. Review.

PMID:
17518431
12.

Live cell detection of caspase-3 activation by a Discosoma-red-fluorescent-protein-based fluorescence resonance energy transfer construct.

Elphick LM, Meinander A, Mikhailov A, Richard M, Toms NJ, Eriksson JE, Kass GE.

Anal Biochem. 2006 Feb 1;349(1):148-55. Epub 2005 Dec 15.

PMID:
16386699

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