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Items: 29


Editorial: Novel Insights Into the Multifaceted Mitotic Kinases.

Elowe S.

Front Cell Dev Biol. 2019 Apr 9;7:51. doi: 10.3389/fcell.2019.00051. eCollection 2019. No abstract available.


Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores.

Dou Z, Prifti DK, Gui P, Liu X, Elowe S, Yao X.

Cells. 2019 Mar 23;8(3). pii: E278. doi: 10.3390/cells8030278. Review.


A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes.

Boutchueng-Djidjou M, Belleau P, Bilodeau N, Fortier S, Bourassa S, Droit A, Elowe S, Faure RL.

PLoS One. 2018 Oct 9;13(10):e0205180. doi: 10.1371/journal.pone.0205180. eCollection 2018.


Proteomic Analysis of NCK1/2 Adaptors Uncovers Paralog-specific Interactions That Reveal a New Role for NCK2 in Cell Abscission During Cytokinesis.

Jacquet K, Banerjee SL, Chartier FJM, Elowe S, Bisson N.

Mol Cell Proteomics. 2018 Oct;17(10):1979-1990. doi: 10.1074/mcp.RA118.000689. Epub 2018 Jul 12.


Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint.

Combes G, Barysz H, Garand C, Gama Braga L, Alharbi I, Thebault P, Murakami L, Bryne DP, Stankovic S, Eyers PA, Bolanos-Garcia VM, Earnshaw WC, Maciejowski J, Jallepalli PV, Elowe S.

Curr Biol. 2018 Mar 19;28(6):872-883.e5. doi: 10.1016/j.cub.2018.02.002. Epub 2018 Mar 1.


Playing polo during mitosis: PLK1 takes the lead.

Combes G, Alharbi I, Braga LG, Elowe S.

Oncogene. 2017 Aug 24;36(34):4819-4827. doi: 10.1038/onc.2017.113. Epub 2017 Apr 24. Review.


Tyr(less) kinase signaling during mitosis.

Elowe S.

Cell Cycle. 2017 Apr 18;16(8):746-748. doi: 10.1080/15384101.2017.1302632. Epub 2017 Mar 15.


Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1).

Caron D, Byrne DP, Thebault P, Soulet D, Landry CR, Eyers PA, Elowe S.

Sci Signal. 2016 Dec 13;9(458):rs14.


A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis.

Fuchs M, Luthold C, Guilbert SM, Varlet AA, Lambert H, Jetté A, Elowe S, Landry J, Lavoie JN.

PLoS Genet. 2015 Oct 23;11(10):e1005582. doi: 10.1371/journal.pgen.1005582. eCollection 2015 Oct.


The Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 Phosphorylation.

Magron A, Elowe S, Carreau M.

PLoS One. 2015 Oct 14;10(10):e0140612. doi: 10.1371/journal.pone.0140612. eCollection 2015.


Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation.

Asghar A, Lajeunesse A, Dulla K, Combes G, Thebault P, Nigg EA, Elowe S.

Nat Commun. 2015 Sep 24;6:8364. doi: 10.1038/ncomms9364.


Sgo1 is a potential therapeutic target for hepatocellular carcinoma.

Wang LH, Yen CJ, Li TN, Elowe S, Wang WC, Wang LH.

Oncotarget. 2015 Feb 10;6(4):2023-33.


The dynamic protein Knl1 - a kinetochore rendezvous.

Ghongane P, Kapanidou M, Asghar A, Elowe S, Bolanos-Garcia VM.

J Cell Sci. 2014 Aug 15;127(Pt 16):3415-23. doi: 10.1242/jcs.149922. Epub 2014 Jul 22. Review.


A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.

Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS.

Biochem J. 2014 Jan 15;457(2):323-34. doi: 10.1042/BJ20131174.


PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.

Kasahara K, Goto H, Izawa I, Kiyono T, Watanabe N, Elowe S, Nigg EA, Inagaki M.

Nat Commun. 2013;4:1882. doi: 10.1038/ncomms2879.


Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint).

Thebault P, Chirgadze DY, Dou Z, Blundell TL, Elowe S, Bolanos-Garcia VM.

Biochem J. 2012 Dec 15;448(3):321-8. doi: 10.1042/BJ20121448.


Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.

Rojas AM, Santamaria A, Malik R, Jensen TS, Körner R, Morilla I, de Juan D, Krallinger M, Hansen DA, Hoffmann R, Lees J, Reid A, Yeats C, Wehner A, Elowe S, Clegg AB, Brunak S, Nigg EA, Orengo C, Valencia A, Ranea JA.

PLoS One. 2012;7(3):e31813. doi: 10.1371/journal.pone.0031813. Epub 2012 Mar 9.


Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint kinases.

Lee S, Thebault P, Freschi L, Beaufils S, Blundell TL, Landry CR, Bolanos-Garcia VM, Elowe S.

J Biol Chem. 2012 Feb 17;287(8):5988-6001. doi: 10.1074/jbc.M111.307355. Epub 2011 Dec 20.


Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint.

Elowe S.

Mol Cell Biol. 2011 Aug;31(15):3085-93. doi: 10.1128/MCB.05326-11. Epub 2011 May 31. Review.


Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1.

Dou Z, von Schubert C, Körner R, Santamaria A, Elowe S, Nigg EA.

PLoS One. 2011 Apr 13;6(4):e18793. doi: 10.1371/journal.pone.0018793.


The Plk1-dependent phosphoproteome of the early mitotic spindle.

Santamaria A, Wang B, Elowe S, Malik R, Zhang F, Bauer M, Schmidt A, Silljé HH, Körner R, Nigg EA.

Mol Cell Proteomics. 2011 Jan;10(1):M110.004457. doi: 10.1074/mcp.M110.004457. Epub 2010 Sep 22.


Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.

Elowe S, Dulla K, Uldschmid A, Li X, Dou Z, Nigg EA.

J Cell Sci. 2010 Jan 1;123(Pt 1):84-94. doi: 10.1242/jcs.056507.


Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions.

Elowe S, Hümmer S, Uldschmid A, Li X, Nigg EA.

Genes Dev. 2007 Sep 1;21(17):2205-19.


Tissue transglutaminase clusters soluble A-type ephrins into functionally active high molecular weight oligomers.

Alford SC, Bazowski J, Lorimer H, Elowe S, Howard PL.

Exp Cell Res. 2007 Dec 10;313(20):4170-9. Epub 2007 Jul 25.


Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer.

Huusko P, Ponciano-Jackson D, Wolf M, Kiefer JA, Azorsa DO, Tuzmen S, Weaver D, Robbins C, Moses T, Allinen M, Hautaniemi S, Chen Y, Elkahloun A, Basik M, Bova GS, Bubendorf L, Lugli A, Sauter G, Schleutker J, Ozcelik H, Elowe S, Pawson T, Trent JM, Carpten JD, Kallioniemi OP, Mousses S.

Nat Genet. 2004 Sep;36(9):979-83. Epub 2004 Aug 8.


Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity.

Tong J, Elowe S, Nash P, Pawson T.

J Biol Chem. 2003 Feb 21;278(8):6111-9. Epub 2002 Dec 16.


The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function.

Henderson JT, Georgiou J, Jia Z, Robertson J, Elowe S, Roder JC, Pawson T.

Neuron. 2001 Dec 20;32(6):1041-56.


Minimal catalytic domain of N-acetylglucosaminyltransferase V.

Korczak B, Le T, Elowe S, Datti A, Dennis JW.

Glycobiology. 2000 Jun;10(6):595-9.


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