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Items: 45

1.

The impact of the rs8005161 polymorphism on G protein-coupled receptor GPR65 (TDAG8) pH-associated activation in intestinal inflammation.

Tcymbarevich IV, Eloranta JJ, Rossel JB, Obialo N, Spalinger M, Cosin-Roger J, Lang S, Kullak-Ublick GA, Wagner CA, Scharl M, Seuwen K, Ruiz PA, Rogler G, de Vallière C, Misselwitz B; Swiss IBD Cohort Study Group.

BMC Gastroenterol. 2019 Jan 7;19(1):2. doi: 10.1186/s12876-018-0922-8.

2.

Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).

de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA.

Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810. doi: 10.1016/j.jcmgh.2016.06.003. eCollection 2016 Nov.

3.

The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment.

de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, Ludwig MG, Okoniewski M, Eloranta JJ, Kullak-Ublick GA, Wagner CA, Rogler G, Seuwen K.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G475-90. doi: 10.1152/ajpgi.00408.2014. Epub 2015 Jul 23.

4.

G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.

de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G.

Inflamm Bowel Dis. 2015 Jun;21(6):1269-81. doi: 10.1097/MIB.0000000000000375.

5.

Anti-inflammatory Function of High-Density Lipoproteins via Autophagy of IκB Kinase.

Gerster R, Eloranta JJ, Hausmann M, Ruiz PA, Cosin-Roger J, Terhalle A, Ziegler U, Kullak-Ublick GA, von Eckardstein A, Rogler G.

Cell Mol Gastroenterol Hepatol. 2014 Dec 26;1(2):171-187.e1. doi: 10.1016/j.jcmgh.2014.12.006. eCollection 2015 Mar.

6.

Functionally significant, rare transcription factor variants in tetralogy of Fallot.

Töpf A, Griffin HR, Glen E, Soemedi R, Brown DL, Hall D, Rahman TJ, Eloranta JJ, Jüngst C, Stuart AG, O'Sullivan J, Keavney BD, Goodship JA.

PLoS One. 2014 Aug 5;9(8):e95453. doi: 10.1371/journal.pone.0095453. eCollection 2014.

7.

The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes.

Schaffner CA, Mwinyi J, Gai Z, Thasler WE, Eloranta JJ, Kullak-Ublick GA.

Liver Int. 2015 Apr;35(4):1152-61. doi: 10.1111/liv.12558. Epub 2014 Apr 29.

8.

Identification of a SIRT1 mutation in a family with type 1 diabetes.

Biason-Lauber A, Böni-Schnetzler M, Hubbard BP, Bouzakri K, Brunner A, Cavelti-Weder C, Keller C, Meyer-Böni M, Meier DT, Brorsson C, Timper K, Leibowitz G, Patrignani A, Bruggmann R, Boily G, Zulewski H, Geier A, Cermak JM, Elliott P, Ellis JL, Westphal C, Knobel U, Eloranta JJ, Kerr-Conte J, Pattou F, Konrad D, Matter CM, Fontana A, Rogler G, Schlapbach R, Regairaz C, Carballido JM, Glaser B, McBurney MW, Pociot F, Sinclair DA, Donath MY.

Cell Metab. 2013 Mar 5;17(3):448-455. doi: 10.1016/j.cmet.2013.02.001.

9.

Fc gamma receptor CD64 modulates the inhibitory activity of infliximab.

Wojtal KA, Rogler G, Scharl M, Biedermann L, Frei P, Fried M, Weber A, Eloranta JJ, Kullak-Ublick GA, Vavricka SR.

PLoS One. 2012;7(8):e43361. doi: 10.1371/journal.pone.0043361. Epub 2012 Aug 24.

10.

Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease.

Attinkara R, Mwinyi J, Truninger K, Regula J, Gaj P, Rogler G, Kullak-Ublick GA, Eloranta JJ; Swiss IBD Cohort Study Group.

BMC Res Notes. 2012 Aug 28;5:461. doi: 10.1186/1756-0500-5-461.

11.

The SLCO1A2 gene, encoding human organic anion-transporting polypeptide 1A2, is transactivated by the vitamin D receptor.

Eloranta JJ, Hiller C, Jüttner M, Kullak-Ublick GA.

Mol Pharmacol. 2012 Jul;82(1):37-46. doi: 10.1124/mol.112.077909. Epub 2012 Apr 3.

PMID:
22474172
12.

The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course.

Mwinyi J, Grete-Wenger C, Eloranta JJ, Kullak-Ublick GA.

PPAR Res. 2012;2012:349469. doi: 10.1155/2012/349469. Epub 2012 Feb 14.

13.

Combined effect of 25-OH vitamin D plasma levels and genetic vitamin D receptor (NR 1I1) variants on fibrosis progression rate in HCV patients.

Baur K, Mertens JC, Schmitt J, Iwata R, Stieger B, Eloranta JJ, Frei P, Stickel F, Dill MT, Seifert B, Ferrari HA, von Eckardstein A, Bochud PY, Müllhaupt B, Geier A; Swiss Hepatitis C Cohort Study Group.

Liver Int. 2012 Apr;32(4):635-43. doi: 10.1111/j.1478-3231.2011.02674.x. Epub 2011 Dec 8.

PMID:
22151003
14.

Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy.

Scharl M, Mwinyi J, Fischbeck A, Leucht K, Eloranta JJ, Arikkat J, Pesch T, Kellermeier S, Mair A, Kullak-Ublick GA, Truninger K, Noreen F, Regula J, Gaj P, Pittet V, Mueller C, Hofmann C, Fried M, McCole DF, Rogler G.

Inflamm Bowel Dis. 2012 May;18(5):900-12. doi: 10.1002/ibd.21913. Epub 2011 Oct 21.

PMID:
22021207
15.

Regulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2.

Ma L, Jüttner M, Kullak-Ublick GA, Eloranta JJ.

Am J Physiol Gastrointest Liver Physiol. 2012 Jan 1;302(1):G123-33. doi: 10.1152/ajpgi.00102.2011. Epub 2011 Oct 20.

16.

Association of a common vitamin D-binding protein polymorphism with inflammatory bowel disease.

Eloranta JJ, Wenger C, Mwinyi J, Hiller C, Gubler C, Vavricka SR, Fried M, Kullak-Ublick GA; Swiss IBD Cohort Study Group.

Pharmacogenet Genomics. 2011 Sep;21(9):559-64. doi: 10.1097/FPC.0b013e328348f70c.

PMID:
21832969
17.

The human organic anion transporter genes OAT5 and OAT7 are transactivated by hepatocyte nuclear factor-1α (HNF-1α).

Klein K, Jüngst C, Mwinyi J, Stieger B, Krempler F, Patsch W, Eloranta JJ, Kullak-Ublick GA.

Mol Pharmacol. 2010 Dec;78(6):1079-87. doi: 10.1124/mol.110.065201. Epub 2010 Sep 9.

PMID:
20829431
18.

Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.

Mwinyi J, Wenger C, Eloranta JJ, Kullak-Ublick GA.

World J Gastroenterol. 2010 Aug 21;16(31):3888-96.

19.

Squamous cell carcinoma of the skin shows a distinct microRNA profile modulated by UV radiation.

Dziunycz P, Iotzova-Weiss G, Eloranta JJ, Läuchli S, Hafner J, French LE, Hofbauer GF.

J Invest Dermatol. 2010 Nov;130(11):2686-9. doi: 10.1038/jid.2010.169. Epub 2010 Jun 24. No abstract available.

20.

Vitamin D3 and its nuclear receptor increase the expression and activity of the human proton-coupled folate transporter.

Eloranta JJ, Zaïr ZM, Hiller C, Häusler S, Stieger B, Kullak-Ublick GA.

Mol Pharmacol. 2009 Nov;76(5):1062-71. doi: 10.1124/mol.109.055392. Epub 2009 Aug 7. Erratum in: Mol Pharmacol. 2010 May;77(5):885. Zaïr, Zoulikha M [added].

PMID:
19666701
21.

Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients.

Wojtal KA, Eloranta JJ, Hruz P, Gutmann H, Drewe J, Staumann A, Beglinger C, Fried M, Kullak-Ublick GA, Vavricka SR.

Drug Metab Dispos. 2009 Sep;37(9):1871-7. doi: 10.1124/dmd.109.027367. Epub 2009 Jun 1.

22.

Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.

Klein K, Kullak-Ublick GA, Wagner M, Trauner M, Eloranta JJ.

Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G936-47. doi: 10.1152/ajpgi.90678.2008. Epub 2009 Feb 19.

23.

The role of FXR in disorders of bile acid homeostasis.

Eloranta JJ, Kullak-Ublick GA.

Physiology (Bethesda). 2008 Oct;23:286-95. doi: 10.1152/physiol.00020.2008. Review.

24.

Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival.

Gee JM, Eloranta JJ, Ibbitt JC, Robertson JF, Ellis IO, Williams T, Nicholson RI, Hurst HC.

J Pathol. 2009 Jan;217(1):32-41. doi: 10.1002/path.2430.

25.

Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.

Zaïr ZM, Eloranta JJ, Stieger B, Kullak-Ublick GA.

Pharmacogenomics. 2008 May;9(5):597-624. doi: 10.2217/14622416.9.5.597. Review.

26.

Regional distribution of solute carrier mRNA expression along the human intestinal tract.

Meier Y, Eloranta JJ, Darimont J, Ismair MG, Hiller C, Fried M, Kullak-Ublick GA, Vavricka SR.

Drug Metab Dispos. 2007 Apr;35(4):590-4. Epub 2007 Jan 12.

PMID:
17220238
27.

fMLP induces Hsp27 expression, attenuates NF-kappaB activation, and confers intestinal epithelial cell protection.

Carlson RM, Vavricka SR, Eloranta JJ, Musch MW, Arvans DL, Kles KA, Walsh-Reitz MM, Kullak-Ublick GA, Chang EB.

Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1070-8. Epub 2006 Dec 21.

28.

Cholestasis protects the liver from ischaemic injury and post-ischaemic inflammation in the mouse.

Georgiev P, Navarini AA, Eloranta JJ, Lang KS, Kullak-Ublick GA, Nocito A, Dahm F, Jochum W, Graf R, Clavien PA.

Gut. 2007 Jan;56(1):121-8. Epub 2006 Jun 8.

29.

The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha.

Saborowski M, Kullak-Ublick GA, Eloranta JJ.

J Pharmacol Exp Ther. 2006 May;317(2):778-85. Epub 2006 Jan 25.

PMID:
16436500
30.

Coordinate transcriptional regulation of transport and metabolism.

Eloranta JJ, Meier PJ, Kullak-Ublick GA.

Methods Enzymol. 2005;400:511-30. Review.

PMID:
16399367
31.

Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine.

Vavricka SR, Musch MW, Fujiya M, Kles K, Chang L, Eloranta JJ, Kullak-Ublick GA, Drabik K, Merlin D, Chang EB.

Pflugers Arch. 2006 Apr;452(1):71-80. Epub 2005 Nov 19.

PMID:
16328452
32.

The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes.

Landrier JF, Eloranta JJ, Vavricka SR, Kullak-Ublick GA.

Am J Physiol Gastrointest Liver Physiol. 2006 Mar;290(3):G476-85. Epub 2005 Nov 3.

34.

The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids.

Popowski K, Eloranta JJ, Saborowski M, Fried M, Meier PJ, Kullak-Ublick GA.

Mol Pharmacol. 2005 May;67(5):1629-38. Epub 2005 Feb 3.

PMID:
15692145
35.

Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer.

Dowen SE, Crnogorac-Jurcevic T, Gangeswaran R, Hansen M, Eloranta JJ, Bhakta V, Brentnall TA, Lüttges J, Klöppel G, Lemoine NR.

Am J Pathol. 2005 Jan;166(1):81-92.

36.

Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism.

Eloranta JJ, Kullak-Ublick GA.

Arch Biochem Biophys. 2005 Jan 15;433(2):397-412. Review.

PMID:
15581596
37.

Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.

Bragança J, Eloranta JJ, Bamforth SD, Ibbitt JC, Hurst HC, Bhattacharya S.

J Biol Chem. 2003 May 2;278(18):16021-9. Epub 2003 Feb 12.

38.

Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.

Eloranta JJ, Hurst HC.

J Biol Chem. 2002 Aug 23;277(34):30798-804. Epub 2002 Jun 18.

39.

Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2.

Bragança J, Swingler T, Marques FI, Jones T, Eloranta JJ, Hurst HC, Shioda T, Bhattacharya S.

J Biol Chem. 2002 Mar 8;277(10):8559-65. Epub 2001 Dec 14.

40.

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.

Bamforth SD, Bragança J, Eloranta JJ, Murdoch JN, Marques FI, Kranc KR, Farza H, Henderson DJ, Hurst HC, Bhattacharya S.

Nat Genet. 2001 Dec;29(4):469-74.

PMID:
11694877
41.

Archaeal RNA polymerase subunits F and P are bona fide homologs of eukaryotic RPB4 and RPB12.

Werner F, Eloranta JJ, Weinzierl RO.

Nucleic Acids Res. 2000 Nov 1;28(21):4299-305.

42.

The Drosophila homologue of the 64 kDa subunit of cleavage stimulation factor interacts with the 77 kDa subunit encoded by the suppressor of forked gene.

Hatton LS, Eloranta JJ, Figueiredo LM, Takagaki Y, Manley JL, O'Hare K.

Nucleic Acids Res. 2000 Jan 15;28(2):520-6.

43.

Crystallization and preliminary diffraction studies of the RNA polymerase subunit RPB5 from Saccharomyces cerevisiae.

Hodach M, Todone F, Eloranta JJ, Onesti S, Weinzierl RO.

Acta Crystallogr D Biol Crystallogr. 1999 Jul;55(Pt 7):1373-5.

PMID:
10393311
44.

RNA polymerase subunit H features a beta-ribbon motif within a novel fold that is present in archaea and eukaryotes.

Thiru A, Hodach M, Eloranta JJ, Kostourou V, Weinzierl RO, Matthews S.

J Mol Biol. 1999 Apr 9;287(4):753-60.

PMID:
10191143
45.

In vitro assembly of an archaeal D-L-N RNA polymerase subunit complex reveals a eukaryote-like structural arrangement.

Eloranta JJ, Kato A, Teng MS, Weinzierl RO.

Nucleic Acids Res. 1998 Dec 15;26(24):5562-7.

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