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Items: 48

1.

Tumor cell escape from therapy-induced senescence.

Saleh T, Tyutyunyk-Massey L, Murray GF, Alotaibi MR, Kawale AS, Elsayed Z, Henderson SC, Yakovlev V, Elmore LW, Toor A, Harada H, Reed J, Landry JW, Gewirtz DA.

Biochem Pharmacol. 2019 Apr;162:202-212. doi: 10.1016/j.bcp.2018.12.013. Epub 2018 Dec 19.

PMID:
30576620
2.

Fibronectin fibrils regulate TGF-β1-induced Epithelial-Mesenchymal Transition.

Griggs LA, Hassan NT, Malik RS, Griffin BP, Martinez BA, Elmore LW, Lemmon CA.

Matrix Biol. 2017 Jul;60-61:157-175. doi: 10.1016/j.matbio.2017.01.001. Epub 2017 Jan 19.

3.

Is Senescence Reversible?

Chakradeo S, Elmore LW, Gewirtz DA.

Curr Drug Targets. 2016;17(4):460-6. Review.

PMID:
26302802
4.

Restoring SIRT6 Expression in Hutchinson-Gilford Progeria Syndrome Cells Impedes Premature Senescence and Formation of Dysmorphic Nuclei.

Endisha H, Merrill-Schools J, Zhao M, Bristol M, Wang X, Kubben N, Elmore LW.

Pathobiology. 2015;82(1):9-20. Epub 2015 Feb 28.

5.

Telomere length: a review of methods for measurement.

Montpetit AJ, Alhareeri AA, Montpetit M, Starkweather AR, Elmore LW, Filler K, Mohanraj L, Burton CW, Menzies VS, Lyon DE, Jackson-Cook CK.

Nurs Res. 2014 Jul-Aug;63(4):289-99. doi: 10.1097/NNR.0000000000000037. Review.

6.

Should clinical studies involving "regenerative injection therapy," strive to incorporate a triad of outcome measures instead of only including clinical outcome measures?

Tucker JD, Ericksen JJ, Goetz LL, Elmore LW.

Osteoarthritis Cartilage. 2014 Jun;22(6):715-7. doi: 10.1016/j.joca.2014.04.005. Epub 2014 Apr 22. No abstract available.

7.

Breast epithelial cell infiltration in enhanced electrospun silk scaffolds.

Maghdouri-White Y, Elmore LW, Bowlin GL, Dréau D.

J Tissue Eng Regen Med. 2016 Feb;10(2):E121-31. doi: 10.1002/term.1778. Epub 2013 Jun 24.

PMID:
23798502
8.

Mesenchymal stem cells in mammary adipose tissue stimulate progression of breast cancer resembling the basal-type.

Zhao M, Sachs PC, Wang X, Dumur CI, Idowu MO, Robila V, Francis MP, Ware J, Beckman M, Rizki A, Holt SE, Elmore LW.

Cancer Biol Ther. 2012 Jul;13(9):782-92. Epub 2012 Jun 6.

9.

Defining essential stem cell characteristics in adipose-derived stromal cells extracted from distinct anatomical sites.

Sachs PC, Francis MP, Zhao M, Brumelle J, Rao RR, Elmore LW, Holt SE.

Cell Tissue Res. 2012 Aug;349(2):505-15. doi: 10.1007/s00441-012-1423-7. Epub 2012 May 25.

10.

Electrospinning adipose tissue-derived extracellular matrix for adipose stem cell culture.

Francis MP, Sachs PC, Madurantakam PA, Sell SA, Elmore LW, Bowlin GL, Holt SE.

J Biomed Mater Res A. 2012 Jul;100(7):1716-24. doi: 10.1002/jbm.a.34126. Epub 2012 Mar 23.

PMID:
22447769
11.

Multipotent adipose stromal cells and breast cancer development: Think globally, act locally.

Zhao M, Dumur CI, Holt SE, Beckman MJ, Elmore LW.

Mol Carcinog. 2010 Nov;49(11):923-7. doi: 10.1002/mc.20675.

12.

Elevated TRF2 in advanced breast cancers with short telomeres.

Diehl MC, Idowu MO, Kimmelshue KN, York TP, Jackson-Cook CK, Turner KC, Holt SE, Elmore LW.

Breast Cancer Res Treat. 2011 Jun;127(3):623-30. doi: 10.1007/s10549-010-0988-7. Epub 2010 Jul 13.

13.

Isolating adipose-derived mesenchymal stem cells from lipoaspirate blood and saline fraction.

Francis MP, Sachs PC, Elmore LW, Holt SE.

Organogenesis. 2010 Jan-Mar;6(1):11-4.

14.

Mechanism of dominant-negative telomerase function.

Nguyen BN, Elmore LW, Holt SE.

Cell Cycle. 2009 Oct 1;8(19):3227-33. Epub 2009 Oct 11.

PMID:
19738429
15.

Elevated expression of nuclear Hsp90 in invasive breast tumors.

Diehl MC, Idowu MO, Kimmelshue K, York TP, Elmore LW, Holt SE.

Cancer Biol Ther. 2009 Oct;8(20):1952-61. Epub 2009 Oct 27.

PMID:
19738418
16.

Genetic inhibition of telomerase results in sensitization and recovery of breast tumor cells.

Poynter KR, Sachs PC, Bright AT, Breed MS, Nguyen BN, Elmore LW, Holt SE.

Mol Cancer Ther. 2009 May;8(5):1319-27. doi: 10.1158/1535-7163.MCT-08-0849. Epub 2009 May 5.

17.

Japanese medaka: a new vertebrate model for studying telomere and telomerase biology.

Au DW, Mok HO, Elmore LW, Holt SE.

Comp Biochem Physiol C Toxicol Pharmacol. 2009 Mar;149(2):161-7. doi: 10.1016/j.cbpc.2008.08.005. Epub 2008 Aug 27.

PMID:
18790082
18.

Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas.

Elmore LW, Forsythe R, Forsythe H, Bright AT, Nasim S, Endo K, Holt SE.

Oncol Rep. 2008 Sep;20(3):613-7.

PMID:
18695913
19.

Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation.

Gewirtz DA, Holt SE, Elmore LW.

Biochem Pharmacol. 2008 Oct 15;76(8):947-57. doi: 10.1016/j.bcp.2008.06.024. Epub 2008 Jul 9.

PMID:
18657518
20.

Recovery from stress is a function of age and telomere length.

Strub GM, Depcrynski A, Elmore LW, Holt SE.

Cell Stress Chaperones. 2008 Dec;13(4):475-82. doi: 10.1007/s12192-008-0047-z. Epub 2008 May 20.

21.

Upregulation of telomerase function during tissue regeneration.

Elmore LW, Norris MW, Sircar S, Bright AT, McChesney PA, Winn RN, Holt SE.

Exp Biol Med (Maywood). 2008 Aug;233(8):958-67. doi: 10.3181/0712-RM-345. Epub 2008 May 14.

PMID:
18480423
22.

Vertebrate marine species as model systems for studying telomeres and telomerase.

McChesney PA, Elmore LW, Holt SE.

Zebrafish. 2005;1(4):349-55. doi: 10.1089/zeb.2005.1.349.

PMID:
18248213
23.

Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin.

Sankala HM, Hait NC, Paugh SW, Shida D, Lépine S, Elmore LW, Dent P, Milstien S, Spiegel S.

Cancer Res. 2007 Nov 1;67(21):10466-74.

24.

Telomerase inhibition as an adjuvant anticancer therapy: it is more than just a waiting game.

Elmore LW, Holt SE.

Expert Opin Ther Targets. 2007 Apr;11(4):427-30.

PMID:
17373872
25.

Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells.

Compton SA, Elmore LW, Haydu K, Jackson-Cook CK, Holt SE.

Mol Cell Biol. 2006 Feb;26(4):1452-62.

26.

Apoptosis as the predominant tumor cell response to chemotherapy and irradiation: a case of TUNEL vision?

Gewirtz DA, Elmore LW.

Curr Opin Investig Drugs. 2005 Dec;6(12):1199. No abstract available.

PMID:
16370385
27.

p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells.

Jones KR, Elmore LW, Jackson-Cook C, Demasters G, Povirk LF, Holt SE, Gewirtz DA.

Int J Radiat Biol. 2005 Jun;81(6):445-58.

PMID:
16308915
28.

Evasion of a single-step, chemotherapy-induced senescence in breast cancer cells: implications for treatment response.

Elmore LW, Di X, Dumur C, Holt SE, Gewirtz DA.

Clin Cancer Res. 2005 Apr 1;11(7):2637-43.

29.

Telomerase resets the homeostatic telomere length and prevents telomere dysfunction in immortalized human cells.

McChesney PA, Turner KC, Jackson-Cook C, Elmore LW, Holt SE.

DNA Cell Biol. 2004 May;23(5):293-300. No abstract available.

PMID:
15199944
30.

Telomere maintenance: at the crossroads of mismatch repair?

Nguyen B, Elmore LW, Holt SE.

Cancer Biol Ther. 2004 Mar;3(3):293-5. Epub 2004 Mar 23. Review. No abstract available.

PMID:
15004529
31.

Telomerase-mediated lifespan extension of human bronchial cells does not affect hexavalent chromium-induced cytotoxicity or genotoxicity.

Wise SS, Elmore LW, Holt SE, Little JE, Antonucci PG, Bryant BH, Wise JP Sr.

Mol Cell Biochem. 2004 Jan;255(1-2):103-11.

PMID:
14971651
32.

Telomerase as a target for cancer immunotherapy.

Nguyen B, Elmore LW, Holt SE.

Cancer Biol Ther. 2003 Mar-Apr;2(2):131-6. Review.

PMID:
12750550
33.

Telomerase protects cancer-prone human cells from chromosomal instability and spontaneous immortalization.

Elmore LW, Turner KC, Gollahon LS, Landon MR, Jackson-Cook CK, Holt SE.

Cancer Biol Ther. 2002 Jul-Aug;1(4):391-7.

PMID:
12432253
34.

Pharmacological approaches to defining the role of chaperones in aging and prostate cancer progression.

Harvey SA, Jensen KO, Elmore LW, Holt SE.

Cell Stress Chaperones. 2002 Apr;7(2):230-4. Review. No abstract available.

35.

Real-time quantitative analysis of telomerase activity in breast tumor specimens using a highly specific and sensitive fluorescent-based assay.

Elmore LW, Forsythe HL, Ferreira-Gonzalez A, Garrett CT, Clark GM, Holt SE.

Diagn Mol Pathol. 2002 Sep;11(3):177-85.

PMID:
12218458
36.

Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction.

Elmore LW, Rehder CW, Di X, McChesney PA, Jackson-Cook CK, Gewirtz DA, Holt SE.

J Biol Chem. 2002 Sep 20;277(38):35509-15. Epub 2002 Jul 5.

37.

Retroviral-mediated expression of telomerase in normal human cells provides a selective growth advantage.

Forsythe HL, Elmore LW, Jensen KO, Landon MR, Holt SE.

Int J Oncol. 2002 Jun;20(6):1137-43.

PMID:
12011990
38.

A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.

Akalin A, Elmore LW, Forsythe HL, Amaker BA, McCollum ED, Nelson PS, Ware JL, Holt SE.

Cancer Res. 2001 Jun 15;61(12):4791-6.

39.

Stable association of hsp90 and p23, but Not hsp70, with active human telomerase.

Forsythe HL, Jarvis JL, Turner JW, Elmore LW, Holt SE.

J Biol Chem. 2001 May 11;276(19):15571-4. Epub 2001 Mar 23.

40.

Expression of c-kit (CD117) in benign and malignant human endometrial epithelium.

Elmore LW, Domson K, Moore JR, Kornstein M, Burks RT.

Arch Pathol Lab Med. 2001 Jan;125(1):146-51.

PMID:
11151069
41.

Telomerase and telomere stability: a new class of tumor suppressor?

Elmore LW, Holt SE.

Mol Carcinog. 2000 May;28(1):1-4.

PMID:
10820482
42.

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis.

Elmore LW, Hancock AR, Chang SF, Wang XW, Chang S, Callahan CP, Geller DA, Will H, Harris CC.

Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14707-12.

44.
46.

Characterization of rat hyperplastic bile ductular epithelial cells in culture and in vivo.

Sirica AE, Elmore LW, Sano N.

Dig Dis Sci. 1991 Apr;36(4):494-501.

PMID:
1672518
47.

Isolation, culture, and transplantation of intrahepatic biliary epithelial cells and oval cells.

Sirica AE, Mathis GA, Sano N, Elmore LW.

Pathobiology. 1990;58(1):44-64. Review.

PMID:
2187478
48.

A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor.

Gooding LR, Elmore LW, Tollefson AE, Brady HA, Wold WS.

Cell. 1988 May 6;53(3):341-6.

PMID:
3365766

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