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Items: 1 to 50 of 93

1.

Visualizing context-dependent calcium signaling in encephalitogenic T cells in vivo by two-photon microscopy.

Kyratsous NI, Bauer IJ, Zhang G, Pesic M, Bartholomäus I, Mues M, Fang P, Wörner M, Everts S, Ellwart JW, Watt JM, Potter BVL, Hohlfeld R, Wekerle H, Kawakami N.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6381-E6389. doi: 10.1073/pnas.1701806114. Epub 2017 Jul 17.

2.

Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement.

Schuh E, Musumeci A, Thaler FS, Laurent S, Ellwart JW, Hohlfeld R, Krug A, Meinl E.

J Immunol. 2017 Apr 15;198(8):3081-3088. doi: 10.4049/jimmunol.1601746. Epub 2017 Mar 10.

3.

Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells.

Zhao L, Zhao Y, Schwarz B, Mysliwietz J, Hartig R, Camaj P, Bao Q, Jauch KW, Guba M, Ellwart JW, Nelson PJ, Bruns CJ.

Int J Oncol. 2016 Jul;49(1):99-110. doi: 10.3892/ijo.2016.3512. Epub 2016 May 10.

4.

Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells.

Pasquarella A, Ebert A, Pereira de Almeida G, Hinterberger M, Kazerani M, Nuber A, Ellwart J, Klein L, Busslinger M, Schotta G.

Development. 2016 May 15;143(10):1788-99. doi: 10.1242/dev.130203. Epub 2016 Mar 24.

5.

Atrx promotes heterochromatin formation at retrotransposons.

Sadic D, Schmidt K, Groh S, Kondofersky I, Ellwart J, Fuchs C, Theis FJ, Schotta G.

EMBO Rep. 2015 Jul;16(7):836-50. doi: 10.15252/embr.201439937. Epub 2015 May 26.

6.

Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer.

Zhao Y, Zhao L, Ischenko I, Bao Q, Schwarz B, Nieß H, Wang Y, Renner A, Mysliwietz J, Jauch KW, Nelson PJ, Ellwart JW, Bruns CJ, Camaj P.

Target Oncol. 2015 Dec;10(4):535-48. doi: 10.1007/s11523-015-0360-2. Epub 2015 Feb 3.

PMID:
25639539
7.

CD8+ CD122+ PD-1- effector cells promote the development of diabetes in NOD mice.

Arndt B, Witkowski L, Ellwart J, Seissler J.

J Leukoc Biol. 2015 Jan;97(1):111-20. doi: 10.1189/jlb.3A0613-344RR. Epub 2014 Nov 11.

PMID:
25387835
8.

Side population cells of pancreatic cancer show characteristics of cancer stem cells responsible for resistance and metastasis.

Niess H, Camaj P, Renner A, Ischenko I, Zhao Y, Krebs S, Mysliwietz J, Jäckel C, Nelson PJ, Blum H, Jauch KW, Ellwart JW, Bruns CJ.

Target Oncol. 2015 Jun;10(2):215-27. doi: 10.1007/s11523-014-0323-z. Epub 2014 Jun 22.

PMID:
24950733
9.

Differential kinetics of antigen dependency of CD4+ and CD8+ T cells.

Rabenstein H, Behrendt AC, Ellwart JW, Naumann R, Horsch M, Beckers J, Obst R.

J Immunol. 2014 Apr 15;192(8):3507-17. doi: 10.4049/jimmunol.1302725. Epub 2014 Mar 17.

10.

T cell-activation in neuromyelitis optica lesions plays a role in their formation.

Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer MT, Machado-Santos J, Mader S, Ellwart JW, Misu T, Fujihara K, Wekerle H, Reindl M, Lassmann H, Bradl M.

Acta Neuropathol Commun. 2013 Dec 24;1:85. doi: 10.1186/2051-5960-1-85.

11.

Stem cell-like side populations in esophageal cancer: a source of chemotherapy resistance and metastases.

Zhao Y, Bao Q, Schwarz B, Zhao L, Mysliwietz J, Ellwart J, Renner A, Hirner H, Niess H, Camaj P, Angele M, Gros S, Izbicki J, Jauch KW, Nelson PJ, Bruns CJ.

Stem Cells Dev. 2014 Jan 15;23(2):180-92. doi: 10.1089/scd.2013.0103. Epub 2013 Nov 13.

PMID:
24021093
12.

Abortive lytic reactivation of KSHV in CBF1/CSL deficient human B cell lines.

Scholz BA, Harth-Hertle ML, Malterer G, Haas J, Ellwart J, Schulz TF, Kempkes B.

PLoS Pathog. 2013;9(5):e1003336. doi: 10.1371/journal.ppat.1003336. Epub 2013 May 16.

13.

Systemic TNFα gene therapy synergizes with liposomal doxorubicine in the treatment of metastatic cancer.

Su B, Cengizeroglu A, Farkasova K, Viola JR, Anton M, Ellwart JW, Haase R, Wagner E, Ogris M.

Mol Ther. 2013 Feb;21(2):300-8. doi: 10.1038/mt.2012.229. Epub 2012 Nov 13.

14.

T cells become licensed in the lung to enter the central nervous system.

Odoardi F, Sie C, Streyl K, Ulaganathan VK, Schläger C, Lodygin D, Heckelsmiller K, Nietfeld W, Ellwart J, Klinkert WE, Lottaz C, Nosov M, Brinkmann V, Spang R, Lehrach H, Vingron M, Wekerle H, Flügel-Koch C, Flügel A.

Nature. 2012 Aug 30;488(7413):675-9. doi: 10.1038/nature11337.

PMID:
22914092
15.

Subcellular localization of FOXP3 in human regulatory and nonregulatory T cells.

Magg T, Mannert J, Ellwart JW, Schmid I, Albert MH.

Eur J Immunol. 2012 Jun;42(6):1627-38. doi: 10.1002/eji.201141838.

16.

Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells.

Oak PS, Kopp F, Thakur C, Ellwart JW, Rapp UR, Ullrich A, Wagner E, Knyazev P, Roidl A.

Int J Cancer. 2012 Dec 15;131(12):2808-19. doi: 10.1002/ijc.27595. Epub 2012 May 21.

17.

Vascular incorporation of endothelial colony-forming cells is essential for functional recovery of murine ischemic tissue following cell therapy.

Schwarz TM, Leicht SF, Radic T, Rodriguez-Arabaolaza I, Hermann PC, Berger F, Saif J, Böcker W, Ellwart JW, Aicher A, Heeschen C.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):e13-21. doi: 10.1161/ATVBAHA.111.239822. Epub 2011 Dec 22. Erratum in: Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):e36.

PMID:
22199368
18.

Effects of the Hedgehog pathway inhibitor GDC-0449 on lung cancer cell lines are mediated by side populations.

Tian F, Mysliwietz J, Ellwart J, Gamarra F, Huber RM, Bergner A.

Clin Exp Med. 2012 Mar;12(1):25-30. doi: 10.1007/s10238-011-0135-8. Epub 2011 Apr 26.

PMID:
21519961
19.

Inhibition of ataxia telangiectasia- and Rad3-related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor-initiating cell fraction.

Gallmeier E, Hermann PC, Mueller MT, Machado JG, Ziesch A, De Toni EN, Palagyi A, Eisen C, Ellwart JW, Rivera J, Rubio-Viqueira B, Hidalgo M, Bunz F, Göke B, Heeschen C.

Stem Cells. 2011 Mar;29(3):418-29. doi: 10.1002/stem.595.

20.

A high-throughput DNA methylation analysis of a single cell.

Kantlehner M, Kirchner R, Hartmann P, Ellwart JW, Alunni-Fabbroni M, Schumacher A.

Nucleic Acids Res. 2011 Apr;39(7):e44. doi: 10.1093/nar/gkq1357. Epub 2011 Jan 25.

21.

Bistability in myo-inositol utilization by Salmonella enterica serovar Typhimurium.

Kröger C, Srikumar S, Ellwart J, Fuchs TM.

J Bacteriol. 2011 Mar;193(6):1427-35. doi: 10.1128/JB.00043-10. Epub 2011 Jan 14.

22.

CD103 is a hallmark of tumor-infiltrating regulatory T cells.

Anz D, Mueller W, Golic M, Kunz WG, Rapp M, Koelzer VH, Ellermeier J, Ellwart JW, Schnurr M, Bourquin C, Endres S.

Int J Cancer. 2011 Nov 15;129(10):2417-26. doi: 10.1002/ijc.25902. Epub 2011 Apr 1.

23.

The CD6 scavenger receptor is differentially expressed on a CD56 natural killer cell subpopulation and contributes to natural killer-derived cytokine and chemokine secretion.

Braun M, Müller B, ter Meer D, Raffegerst S, Simm B, Wilde S, Spranger S, Ellwart J, Mosetter B, Umansky L, Lerchl T, Schendel DJ, Falk CS.

J Innate Immun. 2011;3(4):420-34. doi: 10.1159/000322720. Epub 2010 Dec 18.

24.

ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.

Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF.

EMBO J. 2010 Sep 1;29(17):3020-32. doi: 10.1038/emboj.2010.167. Epub 2010 Jul 30.

25.

A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire.

Liang X, Weigand LU, Schuster IG, Eppinger E, van der Griendt JC, Schub A, Leisegang M, Sommermeyer D, Anderl F, Han Y, Ellwart J, Moosmann A, Busch DH, Uckert W, Peschel C, Krackhardt AM.

J Immunol. 2010 Feb 1;184(3):1617-29. doi: 10.4049/jimmunol.0902155. Epub 2009 Dec 30.

26.

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions.

Bartholomäus I, Kawakami N, Odoardi F, Schläger C, Miljkovic D, Ellwart JW, Klinkert WE, Flügel-Koch C, Issekutz TB, Wekerle H, Flügel A.

Nature. 2009 Nov 5;462(7269):94-8. doi: 10.1038/nature08478. Epub 2009 Oct 14.

PMID:
19829296
27.

Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.

Mueller MT, Hermann PC, Witthauer J, Rubio-Viqueira B, Leicht SF, Huber S, Ellwart JW, Mustafa M, Bartenstein P, D'Haese JG, Schoenberg MH, Berger F, Jauch KW, Hidalgo M, Heeschen C.

Gastroenterology. 2009 Sep;137(3):1102-13. doi: 10.1053/j.gastro.2009.05.053. Epub 2009 Jun 6.

PMID:
19501590
28.

Non-conservative homologous recombination in human B lymphocytes is promoted by activation-induced cytidine deaminase and transcription.

Mierau M, Drexler GA, Kutzera A, Braunschmidt K, Ellwart J, Eckardt-Schupp F, Fritz E, Bachl J, Jungnickel B.

Nucleic Acids Res. 2008 Oct;36(17):5591-601. doi: 10.1093/nar/gkn542. Epub 2008 Aug 30.

29.

Calcium signaling in dendritic cells by human or mycobacterial Hsp70 is caused by contamination and is not required for Hsp70-mediated enhancement of cross-presentation.

Bendz H, Marincek BC, Momburg F, Ellwart JW, Issels RD, Nelson PJ, Noessner E.

J Biol Chem. 2008 Sep 26;283(39):26477-83. doi: 10.1074/jbc.M803310200. Epub 2008 Jul 24.

30.

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing.

Ansel KM, Pastor WA, Rath N, Lapan AD, Glasmacher E, Wolf C, Smith LC, Papadopoulou N, Lamperti ED, Tahiliani M, Ellwart JW, Shi Y, Kremmer E, Rao A, Heissmeyer V.

Nat Struct Mol Biol. 2008 May;15(5):523-30. doi: 10.1038/nsmb.1417. Epub 2008 Apr 27.

31.

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer.

Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ, Heeschen C.

Cell Stem Cell. 2007 Sep 13;1(3):313-23. doi: 10.1016/j.stem.2007.06.002.

32.

Protein evolution by hypermutation and selection in the B cell line DT40.

Arakawa H, Kudo H, Batrak V, Caldwell RB, Rieger MA, Ellwart JW, Buerstedde JM.

Nucleic Acids Res. 2008 Jan;36(1):e1. Epub 2007 Dec 11.

33.

Single lymphocytes from two healthy individuals with mitochondrial point heteroplasmy are mainly homoplasmic.

Lutz-Bonengel S, Sänger T, Parson W, Müller H, Ellwart JW, Follo M, Bonengel B, Niederstätter H, Heinrich M, Schmidt U.

Int J Legal Med. 2008 May;122(3):189-97. Epub 2007 Oct 6.

PMID:
17922134
34.

Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies.

Schuster IG, Busch DH, Eppinger E, Kremmer E, Milosevic S, Hennard C, Kuttler C, Ellwart JW, Frankenberger B, Nössner E, Salat C, Bogner C, Borkhardt A, Kolb HJ, Krackhardt AM.

Blood. 2007 Oct 15;110(8):2931-9. Epub 2007 Jul 12.

35.

Inhibition of IL-6-dependent growth of myeloma cells by an acidic peptide repressing the gp130-mediated activation of Src family kinases.

Hausherr A, Tavares R, Schäffer M, Obermeier A, Miksch C, Mitina O, Ellwart J, Hallek M, Krause G.

Oncogene. 2007 Jul 26;26(34):4987-98. Epub 2007 Feb 19.

PMID:
17310994
36.

Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia.

Aicher A, Rentsch M, Sasaki K, Ellwart JW, Fändrich F, Siebert R, Cooke JP, Dimmeler S, Heeschen C.

Circ Res. 2007 Mar 2;100(4):581-9. Epub 2007 Feb 1.

PMID:
17272807
37.

Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis.

Odoardi F, Kawakami N, Li Z, Cordiglieri C, Streyl K, Nosov M, Klinkert WE, Ellwart JW, Bauer J, Lassmann H, Wekerle H, Flügel A.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):920-5. Epub 2007 Jan 9.

38.

RhoH is important for positive thymocyte selection and T-cell receptor signaling.

Dorn T, Kuhn U, Bungartz G, Stiller S, Bauer M, Ellwart J, Peters T, Scharffetter-Kochanek K, Semmrich M, Laschinger M, Holzmann B, Klinkert WE, Straten PT, Køllgaard T, Sixt M, Brakebusch C.

Blood. 2007 Mar 15;109(6):2346-55. Epub 2006 Nov 21.

39.

Identical TCR beta-chain rearrangements in streptococcal angina and skin lesions of patients with psoriasis vulgaris.

Diluvio L, Vollmer S, Besgen P, Ellwart JW, Chimenti S, Prinz JC.

J Immunol. 2006 Jun 1;176(11):7104-11.

40.

Point mutations in the juxtamembrane domain of FLT3 define a new class of activating mutations in AML.

Reindl C, Bagrintseva K, Vempati S, Schnittger S, Ellwart JW, Wenig K, Hopfner KP, Hiddemann W, Spiekermann K.

Blood. 2006 May 1;107(9):3700-7. Epub 2006 Jan 12.

41.

Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations.

Saribasak H, Saribasak NN, Ipek FM, Ellwart JW, Arakawa H, Buerstedde JM.

J Immunol. 2006 Jan 1;176(1):365-71.

42.

Identification of antigen-capturing cells as basophils.

Mack M, Schneider MA, Moll C, Cihak J, Brühl H, Ellwart JW, Hogarth MP, Stangassinger M, Schlöndorff D.

J Immunol. 2005 Jan 15;174(2):735-41.

43.

FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L).

Bagrintseva K, Geisenhof S, Kern R, Eichenlaub S, Reindl C, Ellwart JW, Hiddemann W, Spiekermann K.

Blood. 2005 May 1;105(9):3679-85. Epub 2004 Dec 30.

44.

KIT exon 8 mutations associated with core-binding factor (CBF)-acute myeloid leukemia (AML) cause hyperactivation of the receptor in response to stem cell factor.

Kohl TM, Schnittger S, Ellwart JW, Hiddemann W, Spiekermann K.

Blood. 2005 Apr 15;105(8):3319-21. Epub 2004 Dec 23.

45.

Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells.

Gehrmann M, Marienhagen J, Eichholtz-Wirth H, Fritz E, Ellwart J, Jäättelä M, Zilch T, Multhoff G.

Cell Death Differ. 2005 Jan;12(1):38-51.

46.

The rate of extrachromosomal homologous recombination within a novel reporter plasmid is elevated in cells lacking functional ATM protein.

Drexler GA, Wilde S, Beisker W, Ellwart J, Eckardt-Schupp F, Fritz E.

DNA Repair (Amst). 2004 Oct 5;3(10):1345-53.

PMID:
15336629
47.

High phylogenetic diversity of transconjugants carrying plasmid pJP4 in an activated sludge-derived microbial community.

Bathe S, Lebuhn M, Ellwart JW, Wuertz S, Hausner M.

FEMS Microbiol Lett. 2004 Jun 15;235(2):215-9.

48.

Heat shock protein 70-reactivity is associated with increased cell surface density of CD94/CD56 on primary natural killer cells.

Gross C, Schmidt-Wolf IG, Nagaraj S, Gastpar R, Ellwart J, Kunz-Schughart LA, Multhoff G.

Cell Stress Chaperones. 2003 Winter;8(4):348-60.

49.

The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis.

Kawakami N, Lassmann S, Li Z, Odoardi F, Ritter T, Ziemssen T, Klinkert WE, Ellwart JW, Bradl M, Krivacic K, Lassmann H, Ransohoff RM, Volk HD, Wekerle H, Linington C, Flügel A.

J Exp Med. 2004 Jan 19;199(2):185-97.

50.

The cell surface-localized heat shock protein 70 epitope TKD induces migration and cytolytic activity selectively in human NK cells.

Gastpar R, Gross C, Rossbacher L, Ellwart J, Riegger J, Multhoff G.

J Immunol. 2004 Jan 15;172(2):972-80.

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