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Items: 1 to 50 of 77

1.

The zinc-finger transcription factor MAZR regulates iNKT cell subset differentiation.

Orola MJ, Tizian C, Zhu C, Andersen L, Gülich AF, Alteneder M, Stojakovic T, Wiedermann U, Trauner M, Ellmeier W, Sakaguchi S.

Cell Mol Life Sci. 2019 May 7. doi: 10.1007/s00018-019-03119-z. [Epub ahead of print]

PMID:
31065747
2.

Differential Requirement of Cd8 Enhancers E8I and E8VI in Cytotoxic Lineage T Cells and in Intestinal Intraepithelial Lymphocytes.

Gülich AF, Preglej T, Hamminger P, Alteneder M, Tizian C, Orola MJ, Muroi S, Taniuchi I, Ellmeier W, Sakaguchi S.

Front Immunol. 2019 Mar 11;10:409. doi: 10.3389/fimmu.2019.00409. eCollection 2019.

3.

Author Correction: Histone deacetylase function in CD4+ T cells.

Ellmeier W, Seiser C.

Nat Rev Immunol. 2019 Apr;19(4):266. doi: 10.1038/s41577-019-0153-4.

PMID:
30862885
4.

NCOR1-a new player on the field of T cell development.

Müller L, Hainberger D, Stolz V, Ellmeier W.

J Leukoc Biol. 2018 Dec;104(6):1061-1068. doi: 10.1002/JLB.1RI0418-168R. Epub 2018 Aug 17. Review.

PMID:
30117609
5.

Histone deacetylase function in CD4+ T cells.

Ellmeier W, Seiser C.

Nat Rev Immunol. 2018 Oct;18(10):617-634. doi: 10.1038/s41577-018-0037-z. Review. Erratum in: Nat Rev Immunol. 2019 Apr;19(4):266.

PMID:
30022149
6.

CXCL5 as Regulator of Neutrophil Function in Cutaneous Melanoma.

Forsthuber A, Lipp K, Andersen L, Ebersberger S, Graña-Castro ', Ellmeier W, Petzelbauer P, Lichtenberger BM, Loewe R.

J Invest Dermatol. 2019 Jan;139(1):186-194. doi: 10.1016/j.jid.2018.07.006. Epub 2018 Oct 4.

PMID:
30009831
7.

The corepressor NCOR1 regulates the survival of single-positive thymocytes.

Müller L, Hainberger D, Stolz V, Hamminger P, Hassan H, Preglej T, Boucheron N, Sakaguchi S, Wiegers GJ, Villunger A, Auwerx J, Ellmeier W.

Sci Rep. 2017 Nov 21;7(1):15928. doi: 10.1038/s41598-017-15918-0.

8.

Immunity meets metabolism and then they start talking.

Nagy L, Ellmeier W.

FEBS Lett. 2017 Oct;591(19):2957-2958. doi: 10.1002/1873-3468.12857. No abstract available.

9.

A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis.

Göschl L, Preglej T, Hamminger P, Bonelli M, Andersen L, Boucheron N, Gülich AF, Müller L, Saferding V, Mufazalov IA, Hirahara K, Seiser C, Matthias P, Penz T, Schuster M, Bock C, Waisman A, Steiner G, Ellmeier W.

J Autoimmun. 2018 Jan;86:51-61. doi: 10.1016/j.jaut.2017.09.008. Epub 2017 Sep 28.

PMID:
28964722
10.

Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling.

de Bruijn MJ, Rip J, van der Ploeg EK, van Greuningen LW, Ta VT, Kil LP, Langerak AW, Rimmelzwaan GF, Ellmeier W, Hendriks RW, Corneth OB.

J Immunol. 2017 Apr 15;198(8):3058-3068. doi: 10.4049/jimmunol.1601285. Epub 2017 Mar 8.

11.

The AMP analog AICAR modulates the Treg/Th17 axis through enhancement of fatty acid oxidation.

Gualdoni GA, Mayer KA, Göschl L, Boucheron N, Ellmeier W, Zlabinger GJ.

FASEB J. 2016 Nov;30(11):3800-3809. Epub 2016 Aug 4.

PMID:
27492924
12.

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Newman DM, Sakaguchi S, Lun A, Preston S, Pellegrini M, Khamina K, Bergthaler A, Nutt SL, Smyth GK, Voss AK, Thomas T, Ellmeier W, Belz GT, Allan RS.

Cell Rep. 2016 Sep 20;16(12):3311-3321. doi: 10.1016/j.celrep.2016.08.056.

13.

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.

Prochazkova J, Sakaguchi S, Owusu M, Mazouzi A, Wiedner M, Velimezi G, Moder M, Turchinovich G, Hladik A, Gurnhofer E, Hayday A, Behrens A, Knapp S, Kenner L, Ellmeier W, Loizou JI.

PLoS Genet. 2015 Nov 6;11(11):e1005645. doi: 10.1371/journal.pgen.1005645. eCollection 2015 Nov.

14.

Rapid multiplex analysis of lipid raft components with single-cell resolution.

Schatzlmaier P, Supper V, Göschl L, Zwirzitz A, Eckerstorfer P, Ellmeier W, Huppa JB, Stockinger H.

Sci Signal. 2015 Sep 22;8(395):rs11. doi: 10.1126/scisignal.aac5584.

PMID:
26396269
15.

MAZR and Runx Factors Synergistically Repress ThPOK during CD8+ T Cell Lineage Development.

Sakaguchi S, Hainberger D, Tizian C, Tanaka H, Okuda T, Taniuchi I, Ellmeier W.

J Immunol. 2015 Sep 15;195(6):2879-87. doi: 10.4049/jimmunol.1500387. Epub 2015 Aug 7.

16.

Molecular control of CD4(+) T cell lineage plasticity and integrity.

Ellmeier W.

Int Immunopharmacol. 2015 Oct;28(2):813-7. doi: 10.1016/j.intimp.2015.03.050. Epub 2015 Apr 9. Review.

PMID:
25864621
17.

Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.

Manne BK, Badolia R, Dangelmaier C, Eble JA, Ellmeier W, Kahn M, Kunapuli SP.

J Biol Chem. 2015 May 1;290(18):11557-68. doi: 10.1074/jbc.M114.629527. Epub 2015 Mar 12.

18.

PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.

Keskin N, Deniz E, Eryilmaz J, Un M, Batur T, Ersahin T, Cetin Atalay R, Sakaguchi S, Ellmeier W, Erman B.

Mol Cell Biol. 2015 May;35(10):1741-53. doi: 10.1128/MCB.01475-14. Epub 2015 Mar 9.

19.

A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.

Sakaguchi S, Hombauer M, Hassan H, Tanaka H, Yasmin N, Naoe Y, Bilic I, Moser MA, Hainberger D, Mayer H, Seiser C, Bergthaler A, Taniuchi I, Ellmeier W.

J Leukoc Biol. 2015 Apr;97(4):635-44. doi: 10.1189/jlb.1HI1113-597RR. Epub 2014 Dec 29.

PMID:
25548254
20.

The non-receptor tyrosine kinase Tec controls assembly and activity of the noncanonical caspase-8 inflammasome.

Zwolanek F, Riedelberger M, Stolz V, Jenull S, Istel F, Köprülü AD, Ellmeier W, Kuchler K.

PLoS Pathog. 2014 Dec 4;10(12):e1004525. doi: 10.1371/journal.ppat.1004525. eCollection 2014 Dec.

21.

HDAC1 controls CD8+ T cell homeostasis and antiviral response.

Tschismarov R, Firner S, Gil-Cruz C, Göschl L, Boucheron N, Steiner G, Matthias P, Seiser C, Ludewig B, Ellmeier W.

PLoS One. 2014 Oct 21;9(10):e110576. doi: 10.1371/journal.pone.0110576. eCollection 2014.

22.

The role of BTB-zinc finger transcription factors during T cell development and in the regulation of T cell-mediated immunity.

Ellmeier W, Taniuchi I.

Curr Top Microbiol Immunol. 2014;381:21-49. doi: 10.1007/82_2014_374. Review.

PMID:
24850219
23.

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

Boucheron N, Tschismarov R, Goeschl L, Moser MA, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Müller L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C, Ellmeier W.

Nat Immunol. 2014 May;15(5):439-448. doi: 10.1038/ni.2864. Epub 2014 Mar 30. Erratum in: Nat Immunol. 2014 Sep;15(9):894. Goeschl, Lisa [corrected to Göschl, Lisa].

24.

The transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcεRI stimulation.

Abramova A, Sakaguchi S, Schebesta A, Hassan H, Boucheron N, Valent P, Roers A, Ellmeier W.

PLoS One. 2013 Oct 17;8(10):e77677. doi: 10.1371/journal.pone.0077677. eCollection 2013.

25.

Transcriptional control of CD4 and CD8 coreceptor expression during T cell development.

Ellmeier W, Haust L, Tschismarov R.

Cell Mol Life Sci. 2013 Dec;70(23):4537-53. doi: 10.1007/s00018-013-1393-2. Epub 2013 Jun 21. Review.

26.

The tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infection.

Köprülü AD, Kastner R, Wienerroither S, Lassnig C, Putz EM, Majer O, Reutterer B, Sexl V, Kuchler K, Müller M, Decker T, Ellmeier W.

PLoS One. 2013;8(3):e60476. doi: 10.1371/journal.pone.0060476. Epub 2013 Mar 27.

27.

Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes.

Mucida D, Husain MM, Muroi S, van Wijk F, Shinnakasu R, Naoe Y, Reis BS, Huang Y, Lambolez F, Docherty M, Attinger A, Shui JW, Kim G, Lena CJ, Sakaguchi S, Miyamoto C, Wang P, Atarashi K, Park Y, Nakayama T, Honda K, Ellmeier W, Kronenberg M, Taniuchi I, Cheroutre H.

Nat Immunol. 2013 Mar;14(3):281-9. doi: 10.1038/ni.2523. Epub 2013 Jan 20.

28.

The role of Tec family kinases in the regulation of T-helper-cell differentiation.

Boucheron N, Ellmeier W.

Int Rev Immunol. 2012 Apr;31(2):133-54. doi: 10.3109/08830185.2012.664798. Review.

PMID:
22449074
29.

Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells.

Hassan H, Sakaguchi S, Tenno M, Kopf A, Boucheron N, Carpenter AC, Egawa T, Taniuchi I, Ellmeier W.

Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18330-5. doi: 10.1073/pnas.1105835108. Epub 2011 Oct 24.

30.

Transcriptional and epigenetic regulation of CD4/CD8 lineage choice.

Taniuchi I, Ellmeier W.

Adv Immunol. 2011;110:71-110. doi: 10.1016/B978-0-12-387663-8.00003-X. Review.

PMID:
21762816
31.

Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.

Ormsby T, Schlecker E, Ferdin J, Tessarz AS, Angelisová P, Köprülü AD, Borte M, Warnatz K, Schulze I, Ellmeier W, Horejsí V, Cerwenka A.

Blood. 2011 Jul 28;118(4):936-45. doi: 10.1182/blood-2010-11-317016. Epub 2011 Jun 9.

PMID:
21659545
32.

Central nervous system mast cells in peripheral inflammatory nociception.

Xanthos DN, Gaderer S, Drdla R, Nuro E, Abramova A, Ellmeier W, Sandkühler J.

Mol Pain. 2011 Jun 3;7:42. doi: 10.1186/1744-8069-7-42.

33.

Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis.

Todoric J, Strobl B, Jais A, Boucheron N, Bayer M, Amann S, Lindroos J, Teperino R, Prager G, Bilban M, Ellmeier W, Krempler F, Müller M, Wagner O, Patsch W, Pospisilik JA, Esterbauer H.

Diabetes. 2011 Jun;60(6):1668-76. doi: 10.2337/db10-1628. Epub 2011 May 2.

34.

RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.

Collins A, Hewitt SL, Chaumeil J, Sellars M, Micsinai M, Allinne J, Parisi F, Nora EP, Bolland DJ, Corcoran AE, Kluger Y, Bosselut R, Ellmeier W, Chong MM, Littman DR, Skok JA.

Immunity. 2011 Mar 25;34(3):303-14. doi: 10.1016/j.immuni.2011.03.004.

35.

Tec family kinases: regulation of FcεRI-mediated mast-cell activation.

Ellmeier W, Abramova A, Schebesta A.

FEBS J. 2011 Jun;278(12):1990-2000. doi: 10.1111/j.1742-4658.2011.08073.x. Epub 2011 Mar 29. Review.

36.

The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset.

Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, Vigl B, Bauer J, Bankoti R, Lassmann H, Epstein MM, Knapp S, Waisman A, Ellmeier W.

J Immunol. 2010 Nov 1;185(9):5111-9. doi: 10.4049/jimmunol.1001734. Epub 2010 Sep 24.

37.

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.

Grausenburger R, Bilic I, Boucheron N, Zupkovitz G, El-Housseiny L, Tschismarov R, Zhang Y, Rembold M, Gaisberger M, Hartl A, Epstein MM, Matthias P, Seiser C, Ellmeier W.

J Immunol. 2010 Sep 15;185(6):3489-97. doi: 10.4049/jimmunol.0903610. Epub 2010 Aug 11.

38.

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.

Sakaguchi S, Hombauer M, Bilic I, Naoe Y, Schebesta A, Taniuchi I, Ellmeier W.

Nat Immunol. 2010 May;11(5):442-8. doi: 10.1038/ni.1860. Epub 2010 Apr 11.

39.

The protein tyrosine kinase Tec regulates mast cell function.

Schmidt U, Abramova A, Boucheron N, Eckelhart E, Schebesta A, Bilic I, Kneidinger M, Unger B, Hammer M, Sibilia M, Valent P, Ellmeier W.

Eur J Immunol. 2009 Nov;39(11):3228-38. doi: 10.1002/eji.200838839.

40.

The role of Tec family kinases in mononuclear phagocytes.

Koprulu AD, Ellmeier W.

Crit Rev Immunol. 2009;29(4):317-33. Review.

PMID:
19673686
41.

Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells.

Blomberg KE, Boucheron N, Lindvall JM, Yu L, Raberger J, Berglöf A, Ellmeier W, Smith CE.

BMC Genomics. 2009 May 18;10:233. doi: 10.1186/1471-2164-10-233.

42.

Impaired T-cell development in the absence of Vav1 and Itk.

Raberger J, Boucheron N, Sakaguchi S, Penninger JM, Ellmeier W.

Eur J Immunol. 2008 Dec;38(12):3530-42. doi: 10.1002/eji.200838388.

43.

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells.

Raberger J, Schebesta A, Sakaguchi S, Boucheron N, Blomberg KE, Berglöf A, Kolbe T, Smith CI, Rülicke T, Ellmeier W.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17919-24. doi: 10.1073/pnas.0805733105. Epub 2008 Nov 12.

44.

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival.

Melcher M, Unger B, Schmidt U, Rajantie IA, Alitalo K, Ellmeier W.

J Immunol. 2008 Jun 15;180(12):8048-56.

45.

Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

Shinohara M, Koga T, Okamoto K, Sakaguchi S, Arai K, Yasuda H, Takai T, Kodama T, Morio T, Geha RS, Kitamura D, Kurosaki T, Ellmeier W, Takayanagi H.

Cell. 2008 Mar 7;132(5):794-806. doi: 10.1016/j.cell.2007.12.037.

46.

The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils.

Kneidinger M, Schmidt U, Rix U, Gleixner KV, Vales A, Baumgartner C, Lupinek C, Weghofer M, Bennett KL, Herrmann H, Schebesta A, Thomas WR, Vrtala S, Valenta R, Lee FY, Ellmeier W, Superti-Furga G, Valent P.

Blood. 2008 Mar 15;111(6):3097-107. doi: 10.1182/blood-2007-08-104372. Epub 2008 Jan 7.

PMID:
18180381
47.

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

Park JH, Adoro S, Lucas PJ, Sarafova SD, Alag AS, Doan LL, Erman B, Liu X, Ellmeier W, Bosselut R, Feigenbaum L, Singer A.

Nat Immunol. 2007 Oct;8(10):1049-59. Epub 2007 Sep 16.

PMID:
17873878
48.

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.

Hantschel O, Rix U, Schmidt U, Bürckstümmer T, Kneidinger M, Schütze G, Colinge J, Bennett KL, Ellmeier W, Valent P, Superti-Furga G.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13283-8. Epub 2007 Aug 7.

49.

Regulation of dendritic cell differentiation and subset distribution by the zinc finger protein CTCF.

Koesters C, Unger B, Bilic I, Schmidt U, Bluml S, Lichtenberger B, Schreiber M, Stockl J, Ellmeier W.

Immunol Lett. 2007 Apr 15;109(2):165-74. Epub 2007 Mar 8.

PMID:
17368809
50.

The role of BTB domain-containing zinc finger proteins in T cell development and function.

Bilic I, Ellmeier W.

Immunol Lett. 2007 Jan 15;108(1):1-9. Epub 2006 Oct 18. Review.

PMID:
17084908

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