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Items: 1 to 50 of 142

1.

WNK4 limits distal calcium losses following acute furosemide treatment.

Ferdaus MZ, Gratreak BDK, Miller L, Si J, McCormick JA, Yang CL, Ellison DH, Terker AS.

Physiol Rep. 2019 Sep;7(17):e14195. doi: 10.14814/phy2.14195.

2.

Optical tissue clearing and immunolabeling in kidney research.

Su XT, Saritas T, Ellison DH.

Methods Cell Biol. 2019;154:31-41. doi: 10.1016/bs.mcb.2019.07.001. Epub 2019 Aug 8.

PMID:
31493820
3.

Optical Clearing and Imaging of Immunolabeled Kidney Tissue.

Saritas T, Puelles VG, Su XT, Ellison DH, Kramann R.

J Vis Exp. 2019 Jul 22;(149). doi: 10.3791/60002.

PMID:
31380853
4.

Enemy Action in the Distal Convoluted Tubule.

Ellison DH, Lin SH.

J Am Soc Nephrol. 2019 Aug;30(8):1345-1348. doi: 10.1681/ASN.2019050475. Epub 2019 Jul 8. No abstract available.

PMID:
31366695
5.

Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies.

Chen L, Clark JZ, Nelson JW, Kaissling B, Ellison DH, Knepper MA.

J Am Soc Nephrol. 2019 Aug;30(8):1358-1364. doi: 10.1681/ASN.2019040415. Epub 2019 Jun 28. No abstract available.

PMID:
31253652
6.

Mechanistic Insights into Loop Diuretic Responsiveness in Heart Failure.

Ellison DH.

Clin J Am Soc Nephrol. 2019 May 7;14(5):650-652. doi: 10.2215/CJN.03590319. Epub 2019 Apr 22. No abstract available.

PMID:
31064772
7.

Clinical Pharmacology in Diuretic Use.

Ellison DH.

Clin J Am Soc Nephrol. 2019 Aug 7;14(8):1248-1257. doi: 10.2215/CJN.09630818. Epub 2019 Apr 1. No abstract available. Erratum in: Clin J Am Soc Nephrol. 2019 Sep 26;:.

PMID:
30936153
8.

Salt-sensitive transcriptome of isolated kidney distal tubule cells.

Swanson EA, Nelson JW, Jeng S, Erspamer KJ, Yang CL, McWeeney S, Ellison DH.

Physiol Genomics. 2019 Apr 1;51(4):125-135. doi: 10.1152/physiolgenomics.00119.2018. Epub 2019 Mar 15.

PMID:
30875275
9.

Animal Models of Hypertension: A Scientific Statement From the American Heart Association.

Lerman LO, Kurtz TW, Touyz RM, Ellison DH, Chade AR, Crowley SD, Mattson DL, Mullins JJ, Osborn J, Eirin A, Reckelhoff JF, Iadecola C, Coffman TM.

Hypertension. 2019 Jun;73(6):e87-e120. doi: 10.1161/HYP.0000000000000090.

10.

From bedside to benchmarks: A physician-scientist workforce dashboard for biomedical research institutions.

Zell A, Smith L, Yanez ND, Guise JM, Pelkey R, Ellison DH.

J Clin Transl Sci. 2018 Oct;2(5):305-311. doi: 10.1017/cts.2018.328. Epub 2018 Dec 7.

11.

Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K+ excretion.

Su XT, Ellison DH, Wang WH.

Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F582-F586. doi: 10.1152/ajprenal.00412.2018. Epub 2019 Jan 9.

PMID:
30623727
12.

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans.

Thosar SS, Rueda JF, Berman AM, Lasarev MR, Herzig MX, Clemons NA, Roberts SA, Bowles NP, Emens JS, Ellison DH, Shea SA.

Am J Physiol Regul Integr Comp Physiol. 2019 Feb 1;316(2):R157-R164. doi: 10.1152/ajpregu.00314.2018. Epub 2018 Dec 6.

PMID:
30521366
13.

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling.

Saritas T, Puelles VG, Su XT, McCormick JA, Welling PA, Ellison DH.

Cell Rep. 2018 Dec 4;25(10):2668-2675.e3. doi: 10.1016/j.celrep.2018.11.021.

14.

Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney.

Thomson MN, Schneider W, Mutig K, Ellison DH, Kettritz R, Bachmann S.

Am J Physiol Renal Physiol. 2019 Feb 1;316(2):F292-F300. doi: 10.1152/ajprenal.00464.2018. Epub 2018 Nov 28.

PMID:
30484345
15.

Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.

Cornelius RJ, Si J, Cuevas CA, Nelson JW, Gratreak BDK, Pardi R, Yang CL, Ellison DH.

J Am Soc Nephrol. 2018 Nov;29(11):2627-2640. doi: 10.1681/ASN.2018030333. Epub 2018 Oct 9.

PMID:
30301860
16.

C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity.

Murillo-de-Ozores AR, Rodríguez-Gama A, Bazúa-Valenti S, Leyva-Ríos K, Vázquez N, Pacheco-Álvarez D, De La Rosa-Velázquez IA, Wengi A, Stone KL, Zhang J, Loffing J, Lifton RP, Yang CL, Ellison DH, Gamba G, Castañeda-Bueno M.

J Biol Chem. 2018 Aug 3;293(31):12209-12221. doi: 10.1074/jbc.RA118.003037. Epub 2018 Jun 19.

17.

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.

Cornelius RJ, Zhang C, Erspamer KJ, Agbor LN, Sigmund CD, Singer JD, Yang CL, Ellison DH.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1006-F1018. doi: 10.1152/ajprenal.00602.2017. Epub 2018 Jun 13.

18.

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway.

Bazúa-Valenti S, Rojas-Vega L, Castañeda-Bueno M, Barrera-Chimal J, Bautista R, Cervantes-Pérez LG, Vázquez N, Plata C, Murillo-de-Ozores AR, González-Mariscal L, Ellison DH, Riccardi D, Bobadilla NA, Gamba G.

J Am Soc Nephrol. 2018 Jul;29(7):1838-1848. doi: 10.1681/ASN.2017111155. Epub 2018 May 30.

19.

Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule.

Wu P, Gao ZX, Su XT, Ellison DH, Hadchouel J, Teulon J, Wang WH.

Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F223-F230. doi: 10.1152/ajprenal.00050.2018. Epub 2018 Apr 18.

20.

Diuretic Treatment in Heart Failure.

Ellison DH, Felker GM.

N Engl J Med. 2018 Feb 15;378(7):684-685. doi: 10.1056/NEJMc1716477. No abstract available.

PMID:
29443667
21.

With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo.

Terker AS, Castañeda-Bueno M, Ferdaus MZ, Cornelius RJ, Erspamer KJ, Su XT, Miller LN, McCormick JA, Wang WH, Gamba G, Yang CL, Ellison DH.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F781-F790. doi: 10.1152/ajprenal.00485.2017. Epub 2018 Feb 7.

22.

Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel.

Wang MX, Cuevas CA, Su XT, Wu P, Gao ZX, Lin DH, McCormick JA, Yang CL, Wang WH, Ellison DH.

Kidney Int. 2018 Apr;93(4):893-902. doi: 10.1016/j.kint.2017.10.023. Epub 2018 Jan 6.

23.

Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension.

Nelson JW, Ferdaus MZ, McCormick JA, Minnier J, Kaul S, Ellison DH, Barnes AP.

Physiol Genomics. 2018 Feb 1;50(2):104-116. doi: 10.1152/physiolgenomics.00111.2017. Epub 2018 Jan 8.

24.

Diuretic Treatment in Heart Failure.

Ellison DH, Felker GM.

N Engl J Med. 2017 Nov 16;377(20):1964-1975. doi: 10.1056/NEJMra1703100. Review. No abstract available. Erratum in: N Engl J Med. 2018 Feb 1;378(5):492.

25.

Treatment of Disorders of Sodium Balance in Chronic Kidney Disease.

Ellison DH.

Adv Chronic Kidney Dis. 2017 Sep;24(5):332-341. doi: 10.1053/j.ackd.2017.07.003. Review.

26.

Compensatory Distal Reabsorption Drives Diuretic Resistance in Human Heart Failure.

Rao VS, Planavsky N, Hanberg JS, Ahmad T, Brisco-Bacik MA, Wilson FP, Jacoby D, Chen M, Tang WHW, Cherney DZI, Ellison DH, Testani JM.

J Am Soc Nephrol. 2017 Nov;28(11):3414-3424. doi: 10.1681/ASN.2016111178. Epub 2017 Jul 24.

27.

Nephron Remodeling Underlies Hyperkalemia in Familial Hyperkalemic Hypertension.

McCormick JA, Ellison DH.

J Am Soc Nephrol. 2017 Sep;28(9):2555-2557. doi: 10.1681/ASN.2017060660. Epub 2017 Jul 13. No abstract available.

28.

Genetic Risk, Lifestyle, and Coronary Artery Disease.

Ellison DH.

N Engl J Med. 2017 Mar 23;376(12):1194. doi: 10.1056/NEJMc1700362. No abstract available.

PMID:
28328343
29.

Pseudohypoaldosteronism Type II.

Ellison DH.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019.
2011 Nov 10 [updated 2017 Feb 16].

30.

WNK Kinase Signaling in Ion Homeostasis and Human Disease.

Shekarabi M, Zhang J, Khanna AR, Ellison DH, Delpire E, Kahle KT.

Cell Metab. 2017 Feb 7;25(2):285-299. doi: 10.1016/j.cmet.2017.01.007. Review.

31.

Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failure.

Ter Maaten JM, Rao VS, Hanberg JS, Perry Wilson F, Bellumkonda L, Assefa M, Sam Broughton J, D'Ambrosi J, Wilson Tang WH, Damman K, Voors AA, Ellison DH, Testani JM.

Eur J Heart Fail. 2017 Aug;19(8):1014-1022. doi: 10.1002/ejhf.757. Epub 2017 Jan 19.

32.

Potassium Sensing by Renal Distal Tubules Requires Kir4.1.

Cuevas CA, Su XT, Wang MX, Terker AS, Lin DH, McCormick JA, Yang CL, Ellison DH, Wang WH.

J Am Soc Nephrol. 2017 Jun;28(6):1814-1825. doi: 10.1681/ASN.2016090935. Epub 2017 Jan 4.

33.

Calcineurin inhibitor cyclosporine A activates renal Na-K-Cl cotransporters via local and systemic mechanisms.

Blankenstein KI, Borschewski A, Labes R, Paliege A, Boldt C, McCormick JA, Ellison DH, Bader M, Bachmann S, Mutig K.

Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F489-F501. doi: 10.1152/ajprenal.00575.2016. Epub 2016 Dec 21.

34.

Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Blanchard A, Bockenhauer D, Bolignano D, Calò LA, Cosyns E, Devuyst O, Ellison DH, Karet Frankl FE, Knoers NV, Konrad M, Lin SH, Vargas-Poussou R.

Kidney Int. 2017 Jan;91(1):24-33. doi: 10.1016/j.kint.2016.09.046.

35.

Diuretic Resistance.

Hoorn EJ, Ellison DH.

Am J Kidney Dis. 2017 Jan;69(1):136-142. doi: 10.1053/j.ajkd.2016.08.027. Epub 2016 Nov 1. Review.

36.

Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases.

Hadchouel J, Ellison DH, Gamba G.

Annu Rev Physiol. 2016;78:367-89. doi: 10.1146/annurev-physiol-021115-105431. Review.

PMID:
26863326
37.

Direct and Indirect Mineralocorticoid Effects Determine Distal Salt Transport.

Terker AS, Yarbrough B, Ferdaus MZ, Lazelle RA, Erspamer KJ, Meermeier NP, Park HJ, McCormick JA, Yang CL, Ellison DH.

J Am Soc Nephrol. 2016 Aug;27(8):2436-45. doi: 10.1681/ASN.2015070815. Epub 2015 Dec 28.

38.

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.

Zhang C, Meermeier NP, Terker AS, Blankenstein KI, Singer JD, Hadchouel J, Ellison DH, Yang CL.

Biochem Biophys Res Commun. 2016 Jan 1;469(1):44-48. doi: 10.1016/j.bbrc.2015.11.067. Epub 2015 Nov 23.

39.

Outstanding translational science at American Society of Hypertension 2015.

Ellison DH.

J Am Soc Hypertens. 2015 Nov;9(11):828-30. doi: 10.1016/j.jash.2015.08.016. Epub 2015 Sep 8. No abstract available.

PMID:
26553599
40.

Potassium and Its Discontents: New Insight, New Treatments.

Ellison DH, Terker AS, Gamba G.

J Am Soc Nephrol. 2016 Apr;27(4):981-9. doi: 10.1681/ASN.2015070751. Epub 2015 Oct 28. Review.

41.

An Integrated View of Potassium Homeostasis.

Hoorn EJ, Loffing J, Ellison DH.

N Engl J Med. 2015 Oct 29;373(18):1786. doi: 10.1056/NEJMc1509656. No abstract available.

42.

Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension.

Lazelle RA, McCully BH, Terker AS, Himmerkus N, Blankenstein KI, Mutig K, Bleich M, Bachmann S, Yang CL, Ellison DH.

J Am Soc Nephrol. 2016 May;27(5):1456-64. doi: 10.1681/ASN.2015040466. Epub 2015 Oct 2.

43.

Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis.

Terker AS, Zhang C, Erspamer KJ, Gamba G, Yang CL, Ellison DH.

Kidney Int. 2016 Jan;89(1):127-34. doi: 10.1038/ki.2015.289. Epub 2016 Jan 4.

44.

Why Your Mother Was Right: How Potassium Intake Reduces Blood Pressure.

Ellison DH, Terker AS.

Trans Am Clin Climatol Assoc. 2015;126:46-55.

45.

Renal mineralocorticoid receptor and electrolyte homeostasis.

Terker AS, Ellison DH.

Am J Physiol Regul Integr Comp Physiol. 2015 Nov 1;309(9):R1068-70. doi: 10.1152/ajpregu.00135.2015. Epub 2015 Jul 1. Review.

46.

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.

Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP.

Nat Med. 2015 Jul;21(7):820-6. doi: 10.1038/nm.3890. Epub 2015 Jun 22.

47.

Calcineurin and Sorting-Related Receptor with A-Type Repeats Interact to Regulate the Renal Na⁺-K⁺-2Cl⁻ Cotransporter.

Borschewski A, Himmerkus N, Boldt C, Blankenstein KI, McCormick JA, Lazelle R, Willnow TE, Jankowski V, Plain A, Bleich M, Ellison DH, Bachmann S, Mutig K.

J Am Soc Nephrol. 2016 Jan;27(1):107-19. doi: 10.1681/ASN.2014070728. Epub 2015 May 12.

48.

Evaluating hyponatremia.

Cohen DM, Ellison DH.

JAMA. 2015 Mar 24-31;313(12):1260-1. doi: 10.1001/jama.2014.13967. No abstract available.

49.

Distal convoluted tubule.

McCormick JA, Ellison DH.

Compr Physiol. 2015 Jan;5(1):45-98. doi: 10.1002/cphy.c140002. Review.

50.

Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride.

Terker AS, Zhang C, McCormick JA, Lazelle RA, Zhang C, Meermeier NP, Siler DA, Park HJ, Fu Y, Cohen DM, Weinstein AM, Wang WH, Yang CL, Ellison DH.

Cell Metab. 2015 Jan 6;21(1):39-50. doi: 10.1016/j.cmet.2014.12.006.

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