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RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe.

Chung CZ, Jaramillo JE, Ellis MJ, Bour DYN, Seidl LE, Jo DHS, Turk MA, Mann MR, Bi Y, Haniford DB, Duennwald ML, Heinemann IU.

Nucleic Acids Res. 2019 Feb 1. doi: 10.1093/nar/gkz043. [Epub ahead of print]


Early Subthreshold Aerobic Exercise for Sport-Related Concussion: A Randomized Clinical Trial.

Leddy JJ, Haider MN, Ellis MJ, Mannix R, Darling SR, Freitas MS, Suffoletto HN, Leiter J, Cordingley DM, Willer B.

JAMA Pediatr. 2019 Feb 4. doi: 10.1001/jamapediatrics.2018.4397. [Epub ahead of print]


Evaluation of a pilot paediatric concussion telemedicine programme for northern communities in Manitoba.

Ellis MJ, Boles S, Derksen V, Dawyduk B, Amadu A, Stelmack K, Kowalchuk M, Russell K.

Int J Circumpolar Health. 2019 Dec;78(1):1573163. doi: 10.1080/22423982.2019.1573163.


Early onset of airway de-recruitment assessed using the forced oscillation technique in subjects with asthma.

Nilsen K, Thien F, Thamrin C, Ellis MJ, Prisk GK, King GG, Thompson BR.

J Appl Physiol (1985). 2019 Jan 31. doi: 10.1152/japplphysiol.00534.2018. [Epub ahead of print]


Health-related quality of life following adolescent sports-related concussion or fracture: a prospective cohort study.

Russell K, Selci E, Black B, Ellis MJ.

J Neurosurg Pediatr. 2019 Jan 15:1-10. doi: 10.3171/2018.8.PEDS18356. [Epub ahead of print]


A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium.

Ellis MJ, Tsai CN, Johnson JW, French S, Elhenawy W, Porwollik S, Andrews-Polymenis H, McClelland M, Magolan J, Coombes BK, Brown ED.

Nat Commun. 2019 Jan 14;10(1):197. doi: 10.1038/s41467-018-08190-x.


A Physiological Approach to Assessment and Rehabilitation of Acute Concussion in Collegiate and Professional Athletes.

Ellis MJ, Leddy J, Cordingley D, Willer B.

Front Neurol. 2018 Dec 20;9:1115. doi: 10.3389/fneur.2018.01115. eCollection 2018.


Concussion education in Canadian medical schools: a 5 year follow-up survey.

Mathieu F, Ellis MJ, Tator CH.

BMC Med Educ. 2018 Dec 20;18(1):316. doi: 10.1186/s12909-018-1416-7.


DNA damage repair defects as a new class of endocrine treatment resistance driver.

Anurag M, Ellis MJ, Haricharan S.

Oncotarget. 2018 Nov 20;9(91):36252-36253. doi: 10.18632/oncotarget.26363. eCollection 2018 Nov 20. No abstract available.


ESR1 fusions drive endocrine therapy resistance and metastasis in breast cancer.

Lei JT, Gou X, Ellis MJ.

Mol Cell Oncol. 2018 Oct 9;5(6):e1526005. doi: 10.1080/23723556.2018.1526005. eCollection 2018.


DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.

Matsunuma R, Chan DW, Kim BJ, Singh P, Han A, Saltzman AB, Cheng C, Lei JT, Wang J, Roberto da Silva L, Sahin E, Leng M, Fan C, Perou CM, Malovannaya A, Ellis MJ.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11978-E11987. doi: 10.1073/pnas.1810598115. Epub 2018 Nov 29.


Author Correction: The prognostic effects of somatic mutations in ER-positive breast cancer.

Griffith OL, Spies NC, Anurag M, Griffith M, Luo J, Tu D, Yeo B, Kunisaki J, Miller CA, Krysiak K, Hundal J, Ainscough BJ, Skidmore ZL, Campbell K, Kumar R, Fronick C, Cook L, Snider JE, Davies S, Kavuri SM, Chang EC, Magrini V, Larson DE, Fulton RS, Liu S, Leung S, Voduc D, Bose R, Dowsett M, Wilson RK, Nielsen TO, Mardis ER, Ellis MJ.

Nat Commun. 2018 Nov 14;9(1):4850. doi: 10.1038/s41467-018-07407-3.


Next generation in vitro liver model design: Combining a permeable polystyrene membrane with a transdifferentiated cell line.

Luetchford KA, Wung N, Argyle IS, Storm MP, Weston SD, Tosh D, Ellis MJ.

J Memb Sci. 2018 Nov 1;565:425-438. doi: 10.1016/j.memsci.2018.07.063.


Long noncoding RNA MALAT1 suppresses breast cancer metastasis.

Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, Xiao Z, Siverly AN, Lawhon SE, Ton BN, Lee H, Zhou Z, Gan B, Nakagawa S, Ellis MJ, Liang H, Hung MC, You MJ, Sun Y, Ma L.

Nat Genet. 2018 Dec;50(12):1705-1715. doi: 10.1038/s41588-018-0252-3. Epub 2018 Oct 22.


Disease-Free and Overall Survival Among Patients With Operable HER2-Positive Breast Cancer Treated With Sequential vs Concurrent Chemotherapy: The ACOSOG Z1041 (Alliance) Randomized Clinical Trial.

Buzdar AU, Suman VJ, Meric-Bernstam F, Leitch AM, Ellis MJ, Boughey JC, Unzeitig GW, Royce ME, Hunt KK.

JAMA Oncol. 2018 Sep 6. doi: 10.1001/jamaoncol.2018.3691. [Epub ahead of print]


The prognostic effects of somatic mutations in ER-positive breast cancer.

Griffith OL, Spies NC, Anurag M, Griffith M, Luo J, Tu D, Yeo B, Kunisaki J, Miller CA, Krysiak K, Hundal J, Ainscough BJ, Skidmore ZL, Campbell K, Kumar R, Fronick C, Cook L, Snider JE, Davies S, Kavuri SM, Chang EC, Magrini V, Larson DE, Fulton RS, Liu S, Leung S, Voduc D, Bose R, Dowsett M, Wilson RK, Nielsen TO, Mardis ER, Ellis MJ.

Nat Commun. 2018 Sep 4;9(1):3476. doi: 10.1038/s41467-018-05914-x. Erratum in: Nat Commun. 2018 Nov 14;9(1):4850.


gpGrouper: A Peptide Grouping Algorithm for Gene-Centric Inference and Quantitation of Bottom-Up Proteomics Data.

Saltzman AB, Leng M, Bhatt B, Singh P, Chan DW, Dobrolecki L, Chandrasekaran H, Choi JM, Jain A, Jung SY, Lewis MT, Ellis MJ, Malovannaya A.

Mol Cell Proteomics. 2018 Nov;17(11):2270-2283. doi: 10.1074/mcp.TIR118.000850. Epub 2018 Aug 9.


Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer.

Lei JT, Shao J, Zhang J, Iglesia M, Chan DW, Cao J, Anurag M, Singh P, He X, Kosaka Y, Matsunuma R, Crowder R, Hoog J, Phommaly C, Goncalves R, Ramalho S, Peres RMR, Punturi N, Schmidt C, Bartram A, Jou E, Devarakonda V, Holloway KR, Lai WV, Hampton O, Rogers A, Tobias E, Parikh PA, Davies SR, Li S, Ma CX, Suman VJ, Hunt KK, Watson MA, Hoadley KA, Thompson EA, Chen X, Kavuri SM, Creighton CJ, Maher CA, Perou CM, Haricharan S, Ellis MJ.

Cell Rep. 2018 Aug 7;24(6):1434-1444.e7. doi: 10.1016/j.celrep.2018.07.009.


Endocrine therapy for ER-positive/HER2-negative metastatic breast cancer.

Reinert T, de Paula B, Shafaee MN, Souza PH, Ellis MJ, Bines J.

Chin Clin Oncol. 2018 Jun;7(3):25. doi: 10.21037/cco.2018.06.06. Review.


Cervical Spine Dysfunction Following Pediatric Sports-Related Head Trauma.

Ellis MJ, McDonald PJ, Olson A, Koenig J, Russell K.

J Head Trauma Rehabil. 2018 Jul 24. doi: 10.1097/HTR.0000000000000411. [Epub ahead of print]


Cancer incidence and mortality rates and trends in Trinidad and Tobago.

Warner WA, Lee TY, Badal K, Williams TM, Bajracharya S, Sundaram V, Bascombe NA, Maharaj R, Lamont-Greene M, Roach A, Bondy M, Ellis MJ, Rebbeck TR, Slovacek S, Luo J, Toriola AT, Llanos AAM.

BMC Cancer. 2018 Jul 4;18(1):712. doi: 10.1186/s12885-018-4625-x.


Evaluation of a Medically Supervised Concussion Protocol for Youth Hockey in Canada.

Ellis MJ, Leiter J, Cordingley DM, Reimer K, Koenig J, Russell KF.

Can J Neurol Sci. 2018 Jul;45(4):424-431. doi: 10.1017/cjn.2018.30. Epub 2018 Jul 3.


The prognostic significance of chronotropic incompetence in patients with severe left ventricular systolic function referred for cardiac transplant assessment.

Patel HC, Yo S, Nanayakkara S, Selkrig L, Ellis MJ, Naughton MT, Kaye DM, Mariani JA.

Eur J Prev Cardiol. 2018 Jan 1:2047487318783880. doi: 10.1177/2047487318783880. [Epub ahead of print] No abstract available.


Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.

Sparano JA, Gray RJ, Makower DF, Pritchard KI, Albain KS, Hayes DF, Geyer CE Jr, Dees EC, Goetz MP, Olson JA Jr, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Paik S, Wood WC, Ravdin PM, Keane MM, Gomez Moreno HL, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Berenberg JL, Abrams J, Sledge GW Jr.

N Engl J Med. 2018 Jul 12;379(2):111-121. doi: 10.1056/NEJMoa1804710. Epub 2018 Jun 3.


FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.

Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM.

Cancer Res. 2018 Aug 1;78(15):4229-4240. doi: 10.1158/0008-5472.CAN-18-0631. Epub 2018 May 29.


Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers.

Anurag M, Punturi N, Hoog J, Bainbridge MN, Ellis MJ, Haricharan S.

Clin Cancer Res. 2018 Oct 1;24(19):4887-4899. doi: 10.1158/1078-0432.CCR-17-3702. Epub 2018 May 23.


Fulvestrant in management of hormone receptor-positive metastatic breast cancer.

Shafaee MN, Ellis MJ.

Future Oncol. 2018 Aug;14(18):1789-1800. doi: 10.2217/fon-2017-0489. Epub 2018 May 22.


Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets.

Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SAW, O'Malley BW, Foulds CE.

Oncogene. 2018 Aug;37(33):4581-4598. doi: 10.1038/s41388-018-0284-2. Epub 2018 May 11.


Current Status of Neoadjuvant Endocrine Therapy in Early Stage Breast Cancer.

Reinert T, Gonçalves R, Ellis MJ.

Curr Treat Options Oncol. 2018 Apr 16;19(5):23. doi: 10.1007/s11864-018-0538-9. Review.


Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.

Nair A, Chung HC, Sun T, Tyagi S, Dobrolecki LE, Dominguez-Vidana R, Kurley SJ, Orellana M, Renwick A, Henke DM, Katsonis P, Schmitt E, Chan DW, Li H, Mao S, Petrovic I, Creighton CJ, Gutierrez C, Dubrulle J, Stossi F, Tyner JW, Lichtarge O, Lin CY, Zhang B, Scott KL, Hilsenbeck SG, Sun J, Yu X, Osborne CK, Schiff R, Christensen JG, Shields DJ, Rimawi MF, Ellis MJ, Shaw CA, Lewis MT, Westbrook TF.

Nat Med. 2018 May;24(4):505-511. doi: 10.1038/nm.4507. Epub 2018 Mar 26.


Health-related quality of life from the FALCON phase III randomised trial of fulvestrant 500 mg versus anastrozole for hormone receptor-positive advanced breast cancer.

Robertson JFR, Cheung KL, Noguchi S, Shao Z, Degboe A, Lichfield J, Thirlwell J, Fazal M, Ellis MJ.

Eur J Cancer. 2018 May;94:206-215. doi: 10.1016/j.ejca.2018.02.026. Epub 2018 Mar 22.


Effects of Celecoxib and Low-dose Aspirin on Outcomes in Adjuvant Aromatase Inhibitor-Treated Patients: CCTG MA.27.

Strasser-Weippl K, Higgins MJ, Chapman JW, Ingle JN, Sledge GW, Budd GT, Ellis MJ, Pritchard KI, Clemons MJ, Badovinac-Crnjevic T, Han L, Gelmon KA, Rabaglio M, Elliott C, Shepherd LE, Goss PE.

J Natl Cancer Inst. 2018 Sep 1;110(9):1003-1008. doi: 10.1093/jnci/djy017.


Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers.

Mundt F, Rajput S, Li S, Ruggles KV, Mooradian AD, Mertins P, Gillette MA, Krug K, Guo Z, Hoog J, Erdmann-Gilmore P, Primeau T, Huang S, Edwards DP, Wang X, Wang X, Kawaler E, Mani DR, Clauser KR, Gao F, Luo J, Davies SR, Johnson GL, Huang KL, Yoon CJ, Ding L, Fenyö D, Ellis MJ, Townsend RR, Held JM, Carr SA, Ma CX.

Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990. Epub 2018 Feb 22.


ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models.

Guo S, Zhang C, Bratton M, Mottamal M, Liu J, Ma P, Zheng S, Zhong Q, Yang L, Wiese TE, Wu Y, Ellis MJ, Matossian M, Burow ME, Miele L, Houtman R, Wang G.

Oncotarget. 2018 Jan 8;9(6):6924-6937. doi: 10.18632/oncotarget.24023. eCollection 2018 Jan 23.


Progression-free survival results in postmenopausal Asian women: subgroup analysis from a phase III randomized trial of fulvestrant 500 mg vs anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON).

Noguchi S, Ellis MJ, Robertson JFR, Thirlwell J, Fazal M, Shao Z.

Breast Cancer. 2018 May;25(3):356-364. doi: 10.1007/s12282-018-0838-8. Epub 2018 Feb 15.


Patient-Specific Alterations in CO2 Cerebrovascular Responsiveness in Acute and Sub-Acute Sports-Related Concussion.

Mutch WAC, Ellis MJ, Ryner LN, McDonald PJ, Morissette MP, Pries P, Essig M, Mikulis DJ, Duffin J, Fisher JA.

Front Neurol. 2018 Jan 24;9:23. doi: 10.3389/fneur.2018.00023. eCollection 2018.


Management and Return to Play Considerations in an Elite Hockey Player with Temporal Lobe Epilepsy.

Ellis MJ, Ritchie L, Essig M, Ng M, Tamayo A, Serletis D.

Curr Sports Med Rep. 2018 Jan;17(1):10-12. doi: 10.1249/JSR.0000000000000439. No abstract available.


Management of an Adolescent Athlete with Sports-Related Concussion and Intraparenchymal Hemorrhage.

Ellis MJ, Barnes J, Cordingley DM, Bunge M, McDonald PJ, Ritchie L.

Curr Sports Med Rep. 2018 Jan;17(1):7-9. doi: 10.1249/JSR.0000000000000438. No abstract available.


Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model.

Pillai SG, Li S, Siddappa CM, Ellis MJ, Watson MA, Aft R.

Breast Cancer Res. 2018 Jan 2;20(1):2. doi: 10.1186/s13058-017-0927-1.


TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer.

Byrd TT, Fousek K, Pignata A, Szot C, Samaha H, Seaman S, Dobrolecki L, Salsman VS, Oo HZ, Bielamowicz K, Landi D, Rainusso N, Hicks J, Powell S, Baker ML, Wels WS, Koch J, Sorensen PH, Deneen B, Ellis MJ, Lewis MT, Hegde M, Fletcher BS, St Croix B, Ahmed N.

Cancer Res. 2018 Jan 15;78(2):489-500. doi: 10.1158/0008-5472.CAN-16-1911. Epub 2017 Nov 28. Erratum in: Cancer Res. 2018 Jun 15;78(12):3403.


Quality Assessments of Long-Term Quantitative Proteomic Analysis of Breast Cancer Xenograft Tissues.

Zhou JY, Chen L, Zhang B, Tian Y, Liu T, Thomas SN, Chen L, Schnaubelt M, Boja E, Hiltke T, Kinsinger CR, Rodriguez H, Davies SR, Li S, Snider JE, Erdmann-Gilmore P, Tabb DL, Townsend RR, Ellis MJ, Rodland KD, Smith RD, Carr SA, Zhang Z, Chan DW, Zhang H.

J Proteome Res. 2017 Dec 1;16(12):4523-4530. doi: 10.1021/acs.jproteome.7b00362. Epub 2017 Nov 16.


Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium.

Ellis MJ, Carfrae LA, Macnair CR, Trussler RS, Brown ED, Haniford DB.

RNA Biol. 2018 Feb 1;15(2):176-181. doi: 10.1080/15476286.2017.1403001. Epub 2017 Dec 8.



Ellis MJ, Ritchie L, McDonald P, Russell K.

Clin J Sport Med. 2018 Nov;28(6):e99-e101. doi: 10.1097/JSM.0000000000000490. No abstract available.


Defects in mismatch repair: the Achilles heel of estrogen receptor positive breast cancer with intrinsic endocrine therapy resistance?

Haricharan S, Ellis MJ.

Oncoscience. 2017 Sep 21;4(7-8):77-78. doi: 10.18632/oncoscience.363. eCollection 2017 Jul. No abstract available.


Chemical genomics reveals mechanistic hypotheses for uncharacterized bioactive molecules in bacteria.

French S, Ellis MJ, Coutts BE, Brown ED.

Curr Opin Microbiol. 2017 Oct;39:42-47. doi: 10.1016/j.mib.2017.09.005. Epub 2017 Sep 26. Review.


Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer.

Doostan I, Karakas C, Kohansal M, Low KH, Ellis MJ, Olson JA Jr, Suman VJ, Hunt KK, Moulder SL, Keyomarsi K.

Clin Cancer Res. 2017 Dec 1;23(23):7288-7300. doi: 10.1158/1078-0432.CCR-17-1544. Epub 2017 Sep 25.


A Phase II Trial of Neoadjuvant MK-2206, an AKT Inhibitor, with Anastrozole in Clinical Stage II or III PIK3CA-Mutant ER-Positive and HER2-Negative Breast Cancer.

Ma CX, Suman V, Goetz MP, Northfelt D, Burkard ME, Ademuyiwa F, Naughton M, Margenthaler J, Aft R, Gray R, Tevaarwerk A, Wilke L, Haddad T, Moynihan T, Loprinzi C, Hieken T, Barnell EK, Skidmore ZL, Feng YY, Krysiak K, Hoog J, Guo Z, Nehring L, Wisinski KB, Mardis E, Hagemann IS, Vij K, Sanati S, Al-Kateb H, Griffith OL, Griffith M, Doyle L, Erlichman C, Ellis MJ.

Clin Cancer Res. 2017 Nov 15;23(22):6823-6832. doi: 10.1158/1078-0432.CCR-17-1260. Epub 2017 Sep 5.


Zirconium amine tris(phenolate): A more effective initiator for biomedical lactide.

Jones MD, Wu X, Chaudhuri J, Davidson MG, Ellis MJ.

Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:69-74. doi: 10.1016/j.msec.2017.03.242. Epub 2017 Mar 29.


Graded Aerobic Treadmill Testing in Adolescent Traumatic Brain Injury Patients.

Cordingley DM, Girardin R, Morissette MP, Reimer K, Leiter J, Russell K, Ellis MJ.

Can J Neurol Sci. 2017 Nov;44(6):684-691. doi: 10.1017/cjn.2017.209. Epub 2017 Aug 29.


CDK4/6 inhibition triggers anti-tumour immunity.

Goel S, DeCristo MJ, Watt AC, BrinJones H, Sceneay J, Li BB, Khan N, Ubellacker JM, Xie S, Metzger-Filho O, Hoog J, Ellis MJ, Ma CX, Ramm S, Krop IE, Winer EP, Roberts TM, Kim HJ, McAllister SS, Zhao JJ.

Nature. 2017 Aug 24;548(7668):471-475. doi: 10.1038/nature23465. Epub 2017 Aug 16.

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