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Chromosome arm aneuploidies shape tumour evolution and drug response.

Shukla A, Nguyen THM, Moka SB, Ellis JJ, Grady JP, Oey H, Cristino AS, Khanna KK, Kroese DP, Krause L, Dray E, Fink JL, Duijf PHG.

Nat Commun. 2020 Jan 23;11(1):449. doi: 10.1038/s41467-020-14286-0.


Best practices in DNA methylation: lessons from inflammatory bowel disease, psoriasis and ankylosing spondylitis.

Whyte JM, Ellis JJ, Brown MA, Kenna TJ.

Arthritis Res Ther. 2019 Jun 3;21(1):133. doi: 10.1186/s13075-019-1922-y. Review.


Whole-genome sequencing of human malignant mesothelioma tumours and cell lines.

Oey H, Daniels M, Relan V, Chee TM, Davidson MR, Yang IA, Ellis JJ, Fong KM, Krause L, Bowman RV.

Carcinogenesis. 2019 Jul 6;40(6):724-734. doi: 10.1093/carcin/bgz066.


Comprehensive genetic screening: The prevalence of maturity-onset diabetes of the young gene variants in a population-based childhood diabetes cohort.

Johnson SR, Ellis JJ, Leo PJ, Anderson LK, Ganti U, Harris JE, Curran JA, McInerney-Leo AM, Paramalingam N, Song X, Conwell LS, Harris M, Jones TW, Brown MA, Davis EA, Duncan EL.

Pediatr Diabetes. 2019 Feb;20(1):57-64. doi: 10.1111/pedi.12766. Epub 2018 Nov 14.


The impact of real-world cardiovascular-related pharmacogenetic testing in an insured population.

Billings J, Racsa PN, Bordenave K, Long CL, Ellis JJ.

Int J Clin Pract. 2018 Jun;72(6):e13088. doi: 10.1111/ijcp.13088. Epub 2018 May 16.


Transcriptome analysis of ankylosing spondylitis patients before and after TNF-α inhibitor therapy reveals the pathways affected.

Wang XB, Ellis JJ, Pennisi DJ, Song X, Batra J, Hollis K, Bradbury LA, Li Z, Kenna TJ, Brown MA.

Genes Immun. 2017 Sep;18(3):184-190. doi: 10.1038/gene.2017.19. Epub 2017 Aug 24.


Environmental enrichment choices of shelter cats.

Ellis JJ, Stryhn H, Spears J, Cockram MS.

Behav Processes. 2017 Aug;141(Pt 3):291-296. doi: 10.1016/j.beproc.2017.03.023. Epub 2017 Apr 3.


Comparative Effectiveness of Rapid-Acting Insulins in Adults with Diabetes.

Racsa PN, Meah Y, Ellis JJ, Saverno KR.

J Manag Care Spec Pharm. 2017 Mar;23(3):291-298. doi: 10.18553/jmcp.2017.23.3.291.


Does previous use affect litter box appeal in multi-cat households?

Ellis JJ, McGowan RTS, Martin F.

Behav Processes. 2017 Aug;141(Pt 3):284-290. doi: 10.1016/j.beproc.2017.02.008. Epub 2017 Feb 14.


RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation.

Wilson JA, Prow NA, Schroder WA, Ellis JJ, Cumming HE, Gearing LJ, Poo YS, Taylor A, Hertzog PJ, Di Giallonardo F, Hueston L, Le Grand R, Tang B, Le TT, Gardner J, Mahalingam S, Roques P, Bird PI, Suhrbier A.

PLoS Pathog. 2017 Feb 16;13(2):e1006155. doi: 10.1371/journal.ppat.1006155. eCollection 2017 Feb.


Calypso: a user-friendly web-server for mining and visualizing microbiome-environment interactions.

Zakrzewski M, Proietti C, Ellis JJ, Hasan S, Brion MJ, Berger B, Krause L.

Bioinformatics. 2017 Mar 1;33(5):782-783. doi: 10.1093/bioinformatics/btw725.


STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction.

Legrand JMD, Roy E, Ellis JJ, Francois M, Brooks AJ, Khosrotehrani K.

J Invest Dermatol. 2016 Sep;136(9):1781-1791. doi: 10.1016/j.jid.2016.04.014. Epub 2016 Apr 27. Review.


SerpinB2 Deficiency Results in a Stratum Corneum Defect and Increased Sensitivity to Topically Applied Inflammatory Agents.

Schroder WA, Anraku I, Le TT, Hirata TD, Nakaya HI, Major L, Ellis JJ, Suhrbier A.

Am J Pathol. 2016 Jun;186(6):1511-23. doi: 10.1016/j.ajpath.2016.02.017. Epub 2016 Apr 22.


Transcriptomic analysis of monocytes and macrophages derived from CLL patients which display differing abilities to respond to therapeutic antibody immune complexes.

Burgess M, Ellis JJ, Mapp S, Mollee P, Mazzieri R, Mattarollo SR, Gill D, Saunders NA.

Genom Data. 2015 Nov 11;7:4-6. doi: 10.1016/j.gdata.2015.11.010. eCollection 2016 Mar.


A novel ATM-dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma.

Spoerri L, Brooks K, Chia K, Grossman G, Ellis JJ, Dahmer-Heath M, Škalamera D, Pavey S, Burmeister B, Gabrielli B.

Pigment Cell Melanoma Res. 2016 May;29(3):329-39. doi: 10.1111/pcmr.12466. Epub 2016 Mar 17.


Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis.

Zhou Y, Zhu G, Charlesworth JC, Simpson S Jr, Rubicz R, Göring HH, Patsopoulos NA, Laverty C, Wu F, Henders A, Ellis JJ, van der Mei I, Montgomery GW, Blangero J, Curran JE, Johnson MP, Martin NG, Nyholt DR, Taylor BV; ANZgene consortium.

Mult Scler. 2016 Nov;22(13):1655-1664. Epub 2016 Jan 27.


Development and Validation of a Predictive Model to Identify Individuals Likely to Have Undiagnosed Chronic Obstructive Pulmonary Disease Using an Administrative Claims Database.

Moretz C, Zhou Y, Dhamane AD, Burslem K, Saverno K, Jain G, Devercelli G, Kaila S, Ellis JJ, Hernandez G, Renda A.

J Manag Care Spec Pharm. 2015 Dec;21(12):1149-59.


A retrospective, matched cohort study of potential drug-drug interaction prevalence and opioid utilization in a diabetic peripheral neuropathy population initiated on pregabalin or duloxetine.

Ellis JJ, Sadosky AB, Ten Eyck LL, Mudumby P, Cappelleri JC, Ndehi L, Suehs BT, Parsons B.

BMC Health Serv Res. 2015 Apr 15;15:159. doi: 10.1186/s12913-015-0829-9.


Impact of roflumilast on exacerbations of COPD, health care utilization, and costs in a predominantly elderly Medicare Advantage population.

Moll K, Sun SX, Ellis JJ, Howe A, Amin A.

Int J Chron Obstruct Pulmon Dis. 2015 Mar 16;10:565-76. doi: 10.2147/COPD.S79025. eCollection 2015.


A bioinformatics tool for epitope-based vaccine design that accounts for human ethnic diversity: application to emerging infectious diseases.

Oyarzun P, Ellis JJ, Gonzalez-Galarza FF, Jones AR, Middleton D, Boden M, Kobe B.

Vaccine. 2015 Mar 3;33(10):1267-73. doi: 10.1016/j.vaccine.2015.01.040. Epub 2015 Jan 25.


Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation.

Róna G, Borsos M, Ellis JJ, Mehdi AM, Christie M, Környei Z, Neubrandt M, Tóth J, Bozóky Z, Buday L, Madarász E, Bodén M, Kobe B, Vértessy BG.

Cell Cycle. 2014;13(22):3551-64. doi: 10.4161/15384101.2014.960740.


Impact of potential pregabalin or duloxetine drug-drug interactions on health care costs and utilization among Medicare members with fibromyalgia.

Ellis JJ, Sadosky AB, Ten Eyck LL, Cappelleri JC, Brown CR, Suehs BT, Parsons B.

Clinicoecon Outcomes Res. 2014 Oct 14;6:389-99. doi: 10.2147/CEOR.S66759. eCollection 2014.


The Einstellung effect in anagram problem solving: evidence from eye movements.

Ellis JJ, Reingold EM.

Front Psychol. 2014 Jul 2;5:679. doi: 10.3389/fpsyg.2014.00679. eCollection 2014.


Behavioural and faecal glucocorticoid metabolite responses of single caging in six cats over 30 days.

Ellis JJ, Protopapadaki V, Stryhn H, Spears J, Cockram MS.

Vet Rec Open. 2014 Nov 8;1(1):e000056. doi: 10.1136/vropen-2014-000056. eCollection 2014.


PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells.

Neviani P, Harb JG, Oaks JJ, Santhanam R, Walker CJ, Ellis JJ, Ferenchak G, Dorrance AM, Paisie CA, Eiring AM, Ma Y, Mao HC, Zhang B, Wunderlich M, May PC, Sun C, Saddoughi SA, Bielawski J, Blum W, Klisovic RB, Solt JA, Byrd JC, Volinia S, Cortes J, Huettner CS, Koschmieder S, Holyoake TL, Devine S, Caligiuri MA, Croce CM, Garzon R, Ogretmen B, Arlinghaus RB, Chen CS, Bittman R, Hokland P, Roy DC, Milojkovic D, Apperley J, Goldman JM, Reid A, Mulloy JC, Bhatia R, Marcucci G, Perrotti D.

J Clin Invest. 2013 Oct;123(10):4144-57. doi: 10.1172/JCI68951. Epub 2013 Sep 3.


Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.

Walker CJ, Oaks JJ, Santhanam R, Neviani P, Harb JG, Ferenchak G, Ellis JJ, Landesman Y, Eisfeld AK, Gabrail NY, Smith CL, Caligiuri MA, Hokland P, Roy DC, Reid A, Milojkovic D, Goldman JM, Apperley J, Garzon R, Marcucci G, Shacham S, Kauffman MG, Perrotti D.

Blood. 2013 Oct 24;122(17):3034-44. doi: 10.1182/blood-2013-04-495374. Epub 2013 Aug 22.


Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation.

Mould AW, Pang Z, Pakusch M, Tonks ID, Stark M, Carrie D, Mukhopadhyay P, Seidel A, Ellis JJ, Deakin J, Wakefield MJ, Krause L, Blewitt ME, Kay GF.

Epigenetics Chromatin. 2013 Jul 2;6(1):19. doi: 10.1186/1756-8935-6-19.


Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target.

Harb JG, Neviani P, Chyla BJ, Ellis JJ, Ferenchak GJ, Oaks JJ, Walker CJ, Hokland P, Roy DC, Caligiuri MA, Marcucci G, Huettner CS, Perrotti D.

Leukemia. 2013 Oct;27(10):1996-2005. doi: 10.1038/leu.2013.151. Epub 2013 May 14.


PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity.

Oyarzún P, Ellis JJ, Bodén M, Kobe B.

BMC Bioinformatics. 2013 Feb 14;14:52. doi: 10.1186/1471-2105-14-52.


Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.

Stark MS, Woods SL, Gartside MG, Bonazzi VF, Dutton-Regester K, Aoude LG, Chow D, Sereduk C, Niemi NM, Tang N, Ellis JJ, Reid J, Zismann V, Tyagi S, Muzny D, Newsham I, Wu Y, Palmer JM, Pollak T, Youngkin D, Brooks BR, Lanagan C, Schmidt CW, Kobe B, MacKeigan JP, Yin H, Brown KM, Gibbs R, Trent J, Hayward NK.

Nat Genet. 2011 Dec 25;44(2):165-9. doi: 10.1038/ng.1041.


Predicting protein kinase specificity: Predikin update and performance in the DREAM4 challenge.

Ellis JJ, Kobe B.

PLoS One. 2011;6(7):e21169. doi: 10.1371/journal.pone.0021169. Epub 2011 Jul 28.


Eye movements reveal solution knowledge prior to insight.

Ellis JJ, Glaholt MG, Reingold EM.

Conscious Cogn. 2011 Sep;20(3):768-76. doi: 10.1016/j.concog.2010.12.007. Epub 2011 Jan 26.


Molecular basis for specificity of nuclear import and prediction of nuclear localization.

Marfori M, Mynott A, Ellis JJ, Mehdi AM, Saunders NF, Curmi PM, Forwood JK, Bodén M, Kobe B.

Biochim Biophys Acta. 2011 Sep;1813(9):1562-77. doi: 10.1016/j.bbamcr.2010.10.013. Epub 2010 Oct 25. Review.


Directionality in protein fold prediction.

Ellis JJ, Huard FP, Deane CM, Srivastava S, Wood GR.

BMC Bioinformatics. 2010 Apr 7;11:172. doi: 10.1186/1471-2105-11-172.


Effects of an adverse-drug-event alert system on cost and quality outcomes in community hospitals.

Piontek F, Kohli R, Conlon P, Ellis JJ, Jablonski J, Kini N.

Am J Health Syst Pharm. 2010 Apr 15;67(8):613-20. doi: 10.2146/ajhp090056.


Satisfaction with current health status in patients with a history of acute coronary syndrome.

Erickson SR, Ellis JJ, Kucukarslan SN, Kline-Rogers E, Smith DE, Eagle KA.

Curr Med Res Opin. 2009 Mar;25(3):683-9. doi: 10.1185/03007990802714473 .


Comparative cost-effectiveness of posaconazole versus fluconazole or itraconazole prophylaxis in patients with prolonged neutropenia.

Collins CD, Ellis JJ, Kaul DR.

Am J Health Syst Pharm. 2008 Dec 1;65(23):2237-43. doi: 10.2146/ajhp070588.


Cost-effectiveness of quantitative fecal lactoferrin assay for diagnosis of symptomatic patients with ileal pouch-anal anastomosis.

Parsi MA, Ellis JJ, Lashner BA.

J Clin Gastroenterol. 2008 Aug;42(7):799-805. doi: 10.1097/MCG.0b013e318074fdfe.


Jefferson: post-DNA.

Ellis JJ.

William Mary Q. 2000;57(1):125-38. No abstract available.


Evaluating conformational changes in protein structures binding RNA.

Ellis JJ, Jones S.

Proteins. 2008 Mar;70(4):1518-26.


Effect of pharmacy practice residency training on residents' knowledge of and interest in clinical research.

Ellis JJ, McCreadie SR, McGregory M, Streetman DS.

Am J Health Syst Pharm. 2007 Oct 1;64(19):2055-63.


Protein-RNA interactions: structural analysis and functional classes.

Ellis JJ, Broom M, Jones S.

Proteins. 2007 Mar 1;66(4):903-11.


Evaluation of clinical research knowledge and interest among pharmacy residents: survey design and validation.

Streetman DS, McCreadie SR, McGregory M, Ellis JJ.

Am J Health Syst Pharm. 2006 Dec 1;63(23):2372-7.


Patient-reported underuse of prescription medications: a comparison of nine surveys.

Kirking DM, Lee JA, Ellis JJ, Briesacher B, McKercher PL.

Med Care Res Rev. 2006 Aug;63(4):427-46.


Gender and perceived severity of cardiac disease: evidence that women are "tougher".

Nau DP, Ellis JJ, Kline-Rogers EM, Mallya U, Eagle KA, Erickson SR.

Am J Med. 2005 Nov;118(11):1256-61.


Perceived work performance of patients who experienced an acute coronary syndrome event.

Ellis JJ, Eagle KA, Kline-Rogers EM, Erickson SR.

Cardiology. 2005;104(3):120-6. Epub 2005 Aug 12.


Validation of the EQ-5D in patients with a history of acute coronary syndrome.

Ellis JJ, Eagle KA, Kline-Rogers EM, Erickson SR.

Curr Med Res Opin. 2005 Aug;21(8):1209-16.


Depressive symptoms and treatment after acute coronary syndrome.

Ellis JJ, Eagle KA, Kline-Rogers EM, Erickson SR.

Int J Cardiol. 2005 Mar 30;99(3):443-7.


Herbal use among US elderly: 2002 National Health Interview Survey.

Bruno JJ, Ellis JJ.

Ann Pharmacother. 2005 Apr;39(4):643-8. Epub 2005 Mar 1.


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