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Items: 26

1.

Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing.

Lewis TA, de Waal L, Wu X, Youngsaye W, Wengner A, Kopitz C, Lange M, Gradl S, Ellermann M, Lienau P, Schreiber SL, Greulich H, Meyerson M.

ACS Med Chem Lett. 2019 Oct 18;10(11):1537-1542. doi: 10.1021/acsmedchemlett.9b00360. eCollection 2019 Nov 14.

PMID:
31749907
2.

Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10-/- Mice.

Ellermann M, Gharaibeh RZ, Fulbright L, Dogan B, Moore LN, Broberg CA, Lopez LR, Rothemich AM, Herzog JW, Rogala A, Gordon IO, Rieder F, Brouwer CR, Simpson KW, Jobin C, Sartor RB, Arthur JC.

Infect Immun. 2019 Oct 18;87(11). pii: e00587-19. doi: 10.1128/IAI.00587-19. Print 2019 Nov.

3.

Taming the Beast: Interplay between Gut Small Molecules and Enteric Pathogens.

Kumar A, Ellermann M, Sperandio V.

Infect Immun. 2019 Aug 21;87(9). pii: e00131-19. doi: 10.1128/IAI.00131-19. Print 2019 Sep. Review.

PMID:
31262983
4.

Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice.

Ellermann M, Gharaibeh RZ, Maharshak N, Peréz-Chanona E, Jobin C, Carroll IM, Arthur JC, Plevy SE, Fodor AA, Brouwer CR, Sartor RB.

Gut Microbes. 2019 Jun 10:1-19. doi: 10.1080/19490976.2019.1599794. [Epub ahead of print]

PMID:
31179826
5.

Intestinal bacterial biofilms modulate mucosal immune responses.

Ellermann M, Sartor RB.

J Immunol Sci. 2018;2(2):13-18.

6.

Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design.

Rahm F, Viklund J, Trésaugues L, Ellermann M, Giese A, Ericsson U, Forsblom R, Ginman T, Günther J, Hallberg K, Lindström J, Persson LB, Silvander C, Talagas A, Díaz-Sáez L, Fedorov O, Huber KVM, Panagakou I, Siejka P, Gorjánácz M, Bauser M, Andersson M.

J Med Chem. 2018 Mar 22;61(6):2533-2551. doi: 10.1021/acs.jmedchem.7b01884. Epub 2018 Mar 7.

PMID:
29485874
7.

The microbiome and the hallmarks of cancer.

Fulbright LE, Ellermann M, Arthur JC.

PLoS Pathog. 2017 Sep 21;13(9):e1006480. doi: 10.1371/journal.ppat.1006480. eCollection 2017 Sep. Review. No abstract available.

8.

Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.

Ellermann M, Eheim A, Rahm F, Viklund J, Guenther J, Andersson M, Ericsson U, Forsblom R, Ginman T, Lindström J, Silvander C, Trésaugues L, Giese A, Bunse S, Neuhaus R, Weiske J, Quanz M, Glasauer A, Nowak-Reppel K, Bader B, Irlbacher H, Meyer H, Queisser N, Bauser M, Haegebarth A, Gorjánácz M.

ACS Chem Biol. 2017 Aug 18;12(8):1986-1992. doi: 10.1021/acschembio.7b00370. Epub 2017 Jul 12.

9.

Siderophore-mediated iron acquisition and modulation of host-bacterial interactions.

Ellermann M, Arthur JC.

Free Radic Biol Med. 2017 Apr;105:68-78. doi: 10.1016/j.freeradbiomed.2016.10.489. Epub 2016 Oct 22. Review.

10.

Adherent-Invasive Escherichia coli Production of Cellulose Influences Iron-Induced Bacterial Aggregation, Phagocytosis, and Induction of Colitis.

Ellermann M, Huh EY, Liu B, Carroll IM, Tamayo R, Sartor RB.

Infect Immun. 2015 Oct;83(10):4068-80. doi: 10.1128/IAI.00904-15. Epub 2015 Jul 27.

11.

Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2.

Maharshak N, Huh EY, Paiboonrungruang C, Shanahan M, Thurlow L, Herzog J, Djukic Z, Orlando R, Pawlinski R, Ellermann M, Borst L, Patel S, Dotan I, Sartor RB, Carroll IM.

Infect Immun. 2015 Jul;83(7):2762-70. doi: 10.1128/IAI.00425-15. Epub 2015 Apr 27.

12.

Molecular detection of bacterial contamination in gnotobiotic rodent units.

Packey CD, Shanahan MT, Manick S, Bower MA, Ellermann M, Tonkonogy SL, Carroll IM, Sartor RB.

Gut Microbes. 2013 Sep-Oct;4(5):361-70. doi: 10.4161/gmic.25824. Epub 2013 Jul 24.

13.

Altered enteric microbiota ecology in interleukin 10-deficient mice during development and progression of intestinal inflammation.

Maharshak N, Packey CD, Ellermann M, Manick S, Siddle JP, Huh EY, Plevy S, Sartor RB, Carroll IM.

Gut Microbes. 2013 Jul-Aug;4(4):316-24. doi: 10.4161/gmic.25486. Epub 2013 Jun 20.

14.

Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application.

Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou KC, Juvonen RO, Petersen D, Deitrich RA, Hurley TD, Vasiliou V.

Pharmacol Rev. 2012 Jul;64(3):520-39. doi: 10.1124/pr.111.005538. Epub 2012 Apr 27. Review.

15.

Catechol-O-methyltransferase in complex with substituted 3'-deoxyribose bisubstrate inhibitors.

Ellermann M, Lerner C, Burgy G, Ehler A, Bissantz C, Jakob-Roetne R, Paulini R, Allemann O, Tissot H, Grünstein D, Stihle M, Diederich F, Rudolph MG.

Acta Crystallogr D Biol Crystallogr. 2012 Mar;68(Pt 3):253-60. doi: 10.1107/S0907444912001138. Epub 2012 Feb 14.

PMID:
22349227
16.

Aromatic rings in chemical and biological recognition: energetics and structures.

Salonen LM, Ellermann M, Diederich F.

Angew Chem Int Ed Engl. 2011 May 16;50(21):4808-42. doi: 10.1002/anie.201007560. Epub 2011 Apr 28. Review.

PMID:
21538733
17.

Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors.

Ellermann M, Paulini R, Jakob-Roetne R, Lerner C, Borroni E, Roth D, Ehler A, Schweizer WB, Schlatter D, Rudolph MG, Diederich F.

Chemistry. 2011 May 27;17(23):6369-81. doi: 10.1002/chem.201003648. Epub 2011 Apr 27.

PMID:
21538606
18.

Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor.

Ellermann M, Jakob-Roetne R, Lerner C, Borroni E, Schlatter D, Roth D, Ehler A, Rudolph MG, Diederich F.

Angew Chem Int Ed Engl. 2009;48(48):9092-6. doi: 10.1002/anie.200904410. No abstract available.

PMID:
19882607
19.

Entirely artificial signal transduction with adrenaline.

Schrader T, Maue M, Ellermann M.

J Recept Signal Transduct Res. 2006;26(5-6):473-85.

PMID:
17118794
20.

[ON MISJUDGMENT OF INTELLIGENCE].

ELLERMANN M.

Militaerlaegen. 1963 Oct;69:31-40. Danish. No abstract available.

PMID:
14097688
21.

[Does psychiatric expertise fulfill its function?].

ELLERMANN M.

Ugeskr Laeger. 1962 Jun 29;124:987-90. Danish. No abstract available.

PMID:
13889906
22.

[Mental disorders and compulsory military service].

ELLERMANN M.

Militaerlaegen. 1961 Dec;67:29-50. Danish. No abstract available.

PMID:
13889907
23.

[The effect of covatine, a new daytime sedative, in outpatients].

ELLERMANN M.

Nord Med. 1955 Oct 6;54(40):1531. Danish. No abstract available.

PMID:
13280115
24.

Further experiences with epidon and some experiments with other anticonvulsant drugs.

ELLERMANN M.

Acta Psychiatr Neurol. 1949;24(3-4):411-20. No abstract available.

PMID:
15390912
25.

Social and clinical features of chronic alcoholism based on a study of 231 male patients.

ELLERMANN M.

J Nerv Ment Dis. 1948 Jun;107(6):556-68. No abstract available.

PMID:
18865000
26.

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