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Items: 9


Canadian regulatory aspects of gene editing technologies.

Ellens KW, Levac D, Pearson C, Savoie A, Strand N, Louter J, Tibelius C.

Transgenic Res. 2019 Aug;28(Suppl 2):165-168. doi: 10.1007/s11248-019-00153-2.


Confronting the catalytic dark matter encoded by sequenced genomes.

Ellens KW, Christian N, Singh C, Satagopam VP, May P, Linster CL.

Nucleic Acids Res. 2017 Nov 16;45(20):11495-11514. doi: 10.1093/nar/gkx937.


Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione.

Peracchi A, Veiga-da-Cunha M, Kuhara T, Ellens KW, Paczia N, Stroobant V, Seliga AK, Marlaire S, Jaisson S, Bommer GT, Sun J, Huebner K, Linster CL, Cooper AJL, Van Schaftingen E.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3233-E3242. doi: 10.1073/pnas.1613736114. Epub 2017 Apr 3.


Evidence that glutamine transaminase and omega-amidase potentially act in tandem to close the methionine salvage cycle in bacteria and plants.

Ellens KW, Richardson LG, Frelin O, Collins J, Ribeiro CL, Hsieh YF, Mullen RT, Hanson AD.

Phytochemistry. 2015 May;113:160-9. doi: 10.1016/j.phytochem.2014.04.012. Epub 2014 May 13.


Identification of mitochondrial coenzyme a transporters from maize and Arabidopsis.

Zallot R, Agrimi G, Lerma-Ortiz C, Teresinski HJ, Frelin O, Ellens KW, Castegna A, Russo A, de Crécy-Lagard V, Mullen RT, Palmieri F, Hanson AD.

Plant Physiol. 2013 Jun;162(2):581-8. doi: 10.1104/pp.113.218081. Epub 2013 Apr 16.


High-level semi-synthetic production of the potent antimalarial artemisinin.

Paddon CJ, Westfall PJ, Pitera DJ, Benjamin K, Fisher K, McPhee D, Leavell MD, Tai A, Main A, Eng D, Polichuk DR, Teoh KH, Reed DW, Treynor T, Lenihan J, Fleck M, Bajad S, Dang G, Dengrove D, Diola D, Dorin G, Ellens KW, Fickes S, Galazzo J, Gaucher SP, Geistlinger T, Henry R, Hepp M, Horning T, Iqbal T, Jiang H, Kizer L, Lieu B, Melis D, Moss N, Regentin R, Secrest S, Tsuruta H, Vazquez R, Westblade LF, Xu L, Yu M, Zhang Y, Zhao L, Lievense J, Covello PS, Keasling JD, Reiling KK, Renninger NS, Newman JD.

Nature. 2013 Apr 25;496(7446):528-32. doi: 10.1038/nature12051. Epub 2013 Apr 10.


Identification and characterization of the missing pyrimidine reductase in the plant riboflavin biosynthesis pathway.

Hasnain G, Frelin O, Roje S, Ellens KW, Ali K, Guan JC, Garrett TJ, de Crécy-Lagard V, Gregory JF 3rd, McCarty DR, Hanson AD.

Plant Physiol. 2013 Jan;161(1):48-56. doi: 10.1104/pp.112.208488. Epub 2012 Nov 13.


Evidence that the folate-dependent proteins YgfZ and MnmEG have opposing effects on growth and on activity of the iron-sulfur enzyme MiaB.

Waller JC, Ellens KW, Hasnain G, Alvarez S, Rocca JR, Hanson AD.

J Bacteriol. 2012 Jan;194(2):362-7. doi: 10.1128/JB.06226-11. Epub 2011 Nov 11.


Mitochondrial and plastidial COG0354 proteins have folate-dependent functions in iron-sulphur cluster metabolism.

Waller JC, Ellens KW, Alvarez S, Loizeau K, Ravanel S, Hanson AD.

J Exp Bot. 2012 Jan;63(1):403-11. doi: 10.1093/jxb/err286. Epub 2011 Oct 6.

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