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SPARC dependent collagen deposition and gemcitabine delivery in a genetically engineered mouse model of pancreas cancer.

Ramu I, Buchholz SM, Patzak MS, Goetze RG, Singh SK, Richards FM, Jodrell DI, Sipos B, Ströbel P, Ellenrieder V, Hessmann E, Neesse A.

EBioMedicine. 2019 Oct 6. pii: S2352-3964(19)30628-0. doi: 10.1016/j.ebiom.2019.09.024. [Epub ahead of print]


EMR + with the AWC improves endoscopic resection speed compared to ESD: a porcine ex-vivo pilot study.

Wedi E, Knoop R, Jung C, Gromski M, Ho CN, Conrad G, Maiss J, Milenovic S, Klemme D, Baulain U, Seif Amir Hosseini A, Ellenrieder V, Koehler P.

Minim Invasive Ther Allied Technol. 2019 Oct 10:1-8. doi: 10.1080/13645706.2019.1673778. [Epub ahead of print]


Distinct Association of Serum Vitamin D Concentration with Disease Activity and Trough Levels of Infliximab and Adalimumab during Inflammatory Bowel Disease Treatment.

Mechie NC, Mavropoulou E, Ellenrieder V, Kunsch S, Cameron S, Amanzada A.

Digestion. 2019 Sep 19:1-10. doi: 10.1159/000502515. [Epub ahead of print]


[Challenges in diagnostics for intestinal tuberculosis - Pitfalls of a forgotten infectious disease: case series and literature review].

Ammer-Herrmenau C, Henrici P, Eiffert H, Amanzada A, Mechie NC, Bremmer F, Seif Amir Hosseini A, Ellenrieder V, Wedi E.

Z Gastroenterol. 2019 Sep;57(9):1067-1076. doi: 10.1055/a-0981-6580. Epub 2019 Sep 16. Review. German.


Prospective comparison of 2D-shearwave elastography in both liver lobes in healthy subjects and in patients with chronic liver disease.

Petzold G, Grieme B, Bremer SCB, Knoop RF, Goetze RG, Ellenrieder V, Kunsch S, Neesse A.

Scand J Gastroenterol. 2019 Sep;54(9):1138-1145. doi: 10.1080/00365521.2019.1653961. Epub 2019 Aug 21.


Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML.

Solovey M, Wang Y, Michel C, Metzeler KH, Herold T, Göthert JR, Ellenrieder V, Hessmann E, Gattenlöhner S, Neubauer A, Pavlinic D, Benes V, Rupp O, Burchert A.

J Hematol Oncol. 2019 Jul 8;12(1):72. doi: 10.1186/s13045-019-0765-y.


[New milestone in adjuvant therapy for pancreatic cancer].

König A, Ellenrieder V, Nitschmann S.

Internist (Berl). 2019 Aug;60(8):881-884. doi: 10.1007/s00108-019-0628-1. Review. German. No abstract available.


Testing of Helicobacter pylori by Endoscopic Biopsy: The Clinical Dilemma of Suppressive Conditions.

Knoop RF, Petzold G, Amanzada A, Bremer SCB, Gress TM, Ellenrieder V, Neesse A, Kunsch S.

Digestion. 2019 Jun 19:1-5. doi: 10.1159/000501270. [Epub ahead of print]


Hiatal hernias in patients with GERD-like symptoms: evaluation of dynamic real-time MRI vs endoscopy.

Seif Amir Hosseini A, Uhlig J, Streit U, Uhlig A, Sprenger T, Wedi E, Ellenrieder V, Ghadimi M, Uecker M, Voit D, Frahm J, Lotz J, Biggemann L.

Eur Radiol. 2019 Jun 11. doi: 10.1007/s00330-019-06284-8. [Epub ahead of print]


Preclinical Evaluation of 1,2-Diamino-4,5-Dibromobenzene in Genetically Engineered Mouse Models of Pancreatic Cancer.

Goetze RG, Buchholz SM, Ou N, Zhang Q, Patil S, Schirmer M, Singh SK, Ellenrieder V, Hessmann E, Lu QB, Neesse A.

Cells. 2019 Jun 9;8(6). pii: E563. doi: 10.3390/cells8060563.


Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression.

Hasselluhn MC, Schmidt GE, Ellenrieder V, Johnsen SA, Hessmann E.

Cell Death Dis. 2019 Jun 6;10(6):446. doi: 10.1038/s41419-019-1682-2.


Endoscopic submucosal dissection with a novel high viscosity injection solution (LiftUp) in an ex vivo model: a prospective randomized study.

Wedi E, Koehler P, Hochberger J, Maiss J, Milenovic S, Gromski M, Ho N, Gabor C, Baulain U, Ellenrieder V, Jung C.

Endosc Int Open. 2019 May;7(5):E641-E646. doi: 10.1055/a-0874-1844. Epub 2019 May 2.


Serum vitamin D but not zinc levels are associated with different disease activity status in patients with inflammatory bowel disease.

Mechie NC, Mavropoulou E, Ellenrieder V, Petzold G, Kunsch S, Neesse A, Amanzada A.

Medicine (Baltimore). 2019 Apr;98(15):e15172. doi: 10.1097/MD.0000000000015172.


Cytomegalovirus colitis in inflammatory bowel disease and after haematopoietic stem cell transplantation: diagnostic accuracy, predictors, risk factors and disease outcome.

Mavropoulou E, Ternes K, Mechie NC, Bremer SCB, Kunsch S, Ellenrieder V, Neesse A, Amanzada A.

BMJ Open Gastroenterol. 2019 Feb 27;6(1):e000258. doi: 10.1136/bmjgast-2018-000258. eCollection 2019.


Chromatin remodelling controls pancreatic tissue fate.

Hessmann E, Ellenrieder V.

Gut. 2019 Jul;68(7):1139-1140. doi: 10.1136/gutjnl-2018-317486. Epub 2019 Mar 19. No abstract available.


Evaluation of liver stiffness by 2D-SWE in combination with non-invasive parameters as predictors for esophageal varices in patients with advanced chronic liver disease.

Petzold G, Tsaknakis B, Bremer SCB, Knoop RF, G Goetze R, Amanzada A, Ellenrieder V, Neesse A, Kunsch S.

Scand J Gastroenterol. 2019 Mar;54(3):342-349. doi: 10.1080/00365521.2019.1585571. Epub 2019 Mar 17.


Real-time MRI for the dynamic assessment of fundoplication failure in patients with gastroesophageal reflux disease.

Seif Amir Hosseini A, Uhlig J, Streit U, Voit D, Uhlig A, Ellenrieder V, Ghadimi M, Sprenger T, Beham A, Uecker M, Frahm J, Lotz J, Biggemann L.

Eur Radiol. 2019 Sep;29(9):4691-4698. doi: 10.1007/s00330-019-06025-x. Epub 2019 Feb 25.


Colonoscopy-assisted application of a 14/6t over-the-scope clip for treatment of a bleeding Dieulafoy lesion in the distal jejunum.

Jung C, Kunsch S, Bremer S, Knoop RF, Ellenrieder V, Wedi E.

Endoscopy. 2019 Apr;51(4):E92-E93. doi: 10.1055/a-0833-8079. Epub 2019 Feb 8. No abstract available.


Cytosolic 5'-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites.

Patzak MS, Kari V, Patil S, Hamdan FH, Goetze RG, Brunner M, Gaedcke J, Kitz J, Jodrell DI, Richards FM, Pilarsky C, Gruetzmann R, Rümmele P, Knösel T, Hessmann E, Ellenrieder V, Johnsen SA, Neesse A.

EBioMedicine. 2019 Feb;40:394-405. doi: 10.1016/j.ebiom.2019.01.037. Epub 2019 Jan 30.


Preclinical evaluation of a novel thermally sensitive co-polymer (LiftUp) for endoscopic resection.

Wedi E, Ho CN, Conrad G, Weiland T, Freidinger S, Wehrmann M, Meining A, Ellenrieder V, Gottwald T, Schurr MO, Hochberger J.

Minim Invasive Ther Allied Technol. 2019 Jan 19:1-8. doi: 10.1080/13645706.2018.1535440. [Epub ahead of print]


Use of an additional working channel for endoscopic mucosal resection (EMR +)of a pedunculated sessile serrated adenoma in the sigmoid colon.

Wedi E, Knoop RF, Jung C, Ellenrieder V, Kunsch S.

Endoscopy. 2019 Mar;51(3):279-280. doi: 10.1055/a-0809-4814. Epub 2019 Jan 11.


Liver Stiffness Measured by 2-Dimensional Shear Wave Elastography: Prospective Evaluation of Healthy Volunteers and Patients With Liver Cirrhosis.

Petzold G, Hofer J, Ellenrieder V, Neesse A, Kunsch S.

J Ultrasound Med. 2019 Jul;38(7):1769-1777. doi: 10.1002/jum.14866. Epub 2018 Dec 11.


Pantoprazole Does not Affect Serum Trough Levels of Tacrolimus and Everolimus in Liver Transplant Recipients.

Bremer SCB, Reinhardt L, Sobotta M, Hasselluhn MC, Lorf T, Ellenrieder V, Schwörer H.

Front Med (Lausanne). 2018 Nov 19;5:320. doi: 10.3389/fmed.2018.00320. eCollection 2018.


High Prevalence of Pathological Hydrogen Breath Tests in Patients with Functional Dyspepsia.

Petzold G, Amanzada A, Gress TM, Ellenrieder V, Neesse A, Kunsch S.

Digestion. 2019;100(3):186-191. doi: 10.1159/000494718. Epub 2018 Nov 14.


Impact of Food Intake on Liver Stiffness Determined by 2-D Shear Wave Elastography: Prospective Interventional Study in 100 Healthy Patients.

Petzold G, Porsche M, Ellenrieder V, Kunsch S, Neesse A.

Ultrasound Med Biol. 2019 Feb;45(2):402-410. doi: 10.1016/j.ultrasmedbio.2018.09.021. Epub 2018 Nov 2.


Gall bladder wall thickening as non-invasive screening parameter for esophageal varices - a comparative endoscopic - sonographic study.

Tsaknakis B, Masri R, Amanzada A, Petzold G, Ellenrieder V, Neesse A, Kunsch S.

BMC Gastroenterol. 2018 Aug 2;18(1):123. doi: 10.1186/s12876-018-0852-5.


HiGHmed - An Open Platform Approach to Enhance Care and Research across Institutional Boundaries.

Haarbrandt B, Schreiweis B, Rey S, Sax U, Scheithauer S, Rienhoff O, Knaup-Gregori P, Bavendiek U, Dieterich C, Brors B, Kraus I, Thoms CM, Jäger D, Ellenrieder V, Bergh B, Yahyapour R, Eils R, Consortium H, Marschollek M.

Methods Inf Med. 2018 Jul;57(S 01):e66-e81. doi: 10.3414/ME18-02-0002. Epub 2018 Jul 17.


Intra- and interobserver variability in the diagnosis of GERD by real-time MRI.

Seif Amir Hosseini A, Beham A, Uhlig J, Streit U, Uhlig A, Ellenrieder V, Joseph AA, Voit D, Frahm J, Uecker M, Lotz J, Biggemann L.

Eur J Radiol. 2018 Jul;104:14-19. doi: 10.1016/j.ejrad.2018.04.029. Epub 2018 Apr 27.


Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models.

Goetze RG, Buchholz SM, Patil S, Petzold G, Ellenrieder V, Hessmann E, Neesse A.

J Vis Exp. 2018 Apr 7;(134). doi: 10.3791/56979.


Induction of Short NFATc1/αA Isoform Interferes with Peripheral B Cell Differentiation.

Muhammad K, Rudolf R, Pham DAT, Klein-Hessling S, Takata K, Matsushita N, Ellenrieder V, Kondo E, Serfling E.

Front Immunol. 2018 Jan 24;9:32. doi: 10.3389/fimmu.2018.00032. eCollection 2018.


Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature.

Wedi E, Orlandini B, Gromski M, Jung CFM, Tchoumak I, Boucher S, Ellenrieder V, Hochberger J.

Clin Endosc. 2018 Jan;51(1):103-108. doi: 10.5946/ce.2017.093. Epub 2018 Jan 31.


Individual endoscopic management of anastomotic insufficiency after esophagectomy for esophageal squamous cell carcinoma and creation of a neostomach.

Wedi E, Schüler P, Kunsch S, Ghadimi BM, Seif Amir Hosseini A, Ellenrieder V, Jung C.

Endoscopy. 2018 Mar;50(3):E69-E71. doi: 10.1055/s-0043-124180. Epub 2018 Jan 12. No abstract available.


Clinicopathological hallmarks and biomarkers of colorectal neuroendocrine neoplasms.

Koenig A, Krug S, Mueller D, Barth PJ, Koenig U, Scharf M, Ellenrieder V, Michl P, Moll R, Homayunfar K, Kann PH, Stroebel P, Gress TM, Rinke A.

PLoS One. 2017 Dec 12;12(12):e0188876. doi: 10.1371/journal.pone.0188876. eCollection 2017.


[Esomeprazol-induced cutaneous lupus erythematosus].

Gliem N, Broekaert SMC, Seitz CS, Schön MP, Ellenrieder V.

Z Gastroenterol. 2017 Sep;55(9):861-865. doi: 10.1055/s-0043-113833. Epub 2017 Sep 12. German.


A case report of delayed intra-abdominal and intra-luminal haemorrhage after polypectomy.

Neesse A, Grade M, Dango S, Ghadimi M, Ellenrieder V, Kunsch S, Amanzada A.

Z Gastroenterol. 2017 Oct;55(10):1009-1013. doi: 10.1055/s-0043-108125. Epub 2017 Oct 11.


Autoimmune Pancreatitis in Germany: Rare but Relevant.

Petzold G, Ellenrieder V, Neesse A.

Digestion. 2017 Nov;96(4):185-186. doi: 10.1159/000481251. Epub 2017 Sep 29. No abstract available.


[Erratum to: Spontaneous remission of HCV infection after autologous stem cell transplantation in a 58-year-old man].

Reinhardt L, Eiffert H, Wulf G, Ströbel P, Bremer SCB, Amanzada A, Ellenrieder V, Neesse A.

Internist (Berl). 2017 Jun;58(6):626. doi: 10.1007/s00108-017-0228-x. German. No abstract available.


Krüppel-like Transcription Factor KLF10 Suppresses TGFβ-Induced Epithelial-to-Mesenchymal Transition via a Negative Feedback Mechanism.

Mishra VK, Subramaniam M, Kari V, Pitel KS, Baumgart SJ, Naylor RM, Nagarajan S, Wegwitz F, Ellenrieder V, Hawse JR, Johnsen SA.

Cancer Res. 2017 May 1;77(9):2387-2400. doi: 10.1158/0008-5472.CAN-16-2589. Epub 2017 Mar 1.


[Spontaneous remission of HCV infection after autologous stem cell transplantation in a 58-year-old man].

Reinhardt L, Eiffert H, Wulf G, Ströbel P, Bremer SCB, Amanzada A, Ellenrieder V, Neesse A.

Internist (Berl). 2017 Jun;58(6):621-625. doi: 10.1007/s00108-017-0206-3. German. Erratum in: Internist (Berl). 2017 Jun;58(6):626.


Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity.

Chen NM, Neesse A, Dyck ML, Steuber B, Koenig AO, Lubeseder-Martellato C, Winter T, Forster T, Bohnenberger H, Kitz J, Reuter-Jessen K, Griesmann H, Gaedcke J, Grade M, Zhang JS, Tsai WC, Siveke J, Schildhaus HU, Ströbel P, Johnsen SA, Ellenrieder V, Hessmann E.

Gastroenterology. 2017 May;152(6):1507-1520.e15. doi: 10.1053/j.gastro.2017.01.043. Epub 2017 Feb 8.


Relevance of surgery in patients with non-variceal upper gastrointestinal bleeding.

Dango S, Beißbarth T, Weiss E, Seif Amir Hosseini A, Raddatz D, Ellenrieder V, Lotz J, Ghadimi BM, Beham A.

Langenbecks Arch Surg. 2017 May;402(3):509-519. doi: 10.1007/s00423-017-1552-2. Epub 2017 Jan 14.


Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer.

Hessmann E, Patzak MS, Klein L, Chen N, Kari V, Ramu I, Bapiro TE, Frese KK, Gopinathan A, Richards FM, Jodrell DI, Verbeke C, Li X, Heuchel R, Löhr JM, Johnsen SA, Gress TM, Ellenrieder V, Neesse A.

Gut. 2018 Mar;67(3):497-507. doi: 10.1136/gutjnl-2016-311954. Epub 2017 Jan 10.


Severe Acute Respiratory Distress Syndrome during Infliximab Therapy in a Patient with Crohn Disease.

Schoehl J, Mechie NC, Schwoerer H, Moerer O, Quintel M, Buck C, Ellenrieder V, Neesse A, Amanzada A.

Case Rep Gastroenterol. 2016 Oct 18;10(3):574-580. eCollection 2016 Sep-Dec.


Epigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?

Hessmann E, Johnsen SA, Siveke JT, Ellenrieder V.

Gut. 2017 Jan;66(1):168-179. doi: 10.1136/gutjnl-2016-312539. Epub 2016 Nov 3. Review.


[Severe hypoglycemia following tramadol intake in a 79 year old non-diabetic patient].

Kürten C, Tzvetkov M, Ellenrieder V, Schwörer H.

Dtsch Med Wochenschr. 2016 Sep;141(20):1480-1482. Epub 2016 Oct 4. German.


Open Surgical versus Minimal Invasive Necrosectomy of the Pancreas-A Retrospective Multicenter Analysis of the German Pancreatitis Study Group.

Rasch S, Phillip V, Reichel S, Rau B, Zapf C, Rosendahl J, Halm U, Zachäus M, Müller M, Kleger A, Neesse A, Hampe J, Ellrichmann M, Rückert F, Strauß P, Arlt A, Ellenrieder V, Gress TM, Hartwig W, Klar E, Mössner J, Post S, Schmid RM, Seufferlein T, Siech M, Werner J, Will U, Algül H.

PLoS One. 2016 Sep 26;11(9):e0163651. doi: 10.1371/journal.pone.0163651. eCollection 2016.


NEMO-CXCL12/CXCR4 axis: a novel vantage point for antifibrotic therapies in chronic pancreatitis?

Neesse A, Ellenrieder V.

Gut. 2017 Feb;66(2):211-212. doi: 10.1136/gutjnl-2016-312874. Epub 2016 Sep 2. No abstract available.


Current Standard and Future Perspectives in First- and Second-Line Treatment of Metastatic Pancreatic Adenocarcinoma.

Ellenrieder V, König A, Seufferlein T.

Digestion. 2016;94(1):44-9. doi: 10.1159/000447739. Epub 2016 Jul 21. Review.


A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development.

Klein-Hessling S, Rudolf R, Muhammad K, Knobeloch KP, Maqbool MA, Cauchy P, Andrau JC, Avots A, Talora C, Ellenrieder V, Screpanti I, Serfling E, Patra AK.

Nat Commun. 2016 Jun 17;7:11841. doi: 10.1038/ncomms11841.


GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression.

Baumgart S, Chen NM, Zhang JS, Billadeau DD, Gaisina IN, Kozikowski AP, Singh SK, Fink D, Ströbel P, Klindt C, Zhang L, Bamlet WR, Koenig A, Hessmann E, Gress TM, Ellenrieder V, Neesse A.

Mol Cancer Ther. 2016 Mar;15(3):491-502. doi: 10.1158/1535-7163.MCT-15-0309. Epub 2016 Jan 28.

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