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Choosing the harder road: Naming the challenges for families in person-centred planning.
Ellem K, Chenoweth L, Edwards R.
J Intellect Disabil. 2019 Sep;23(3):397-412. doi: 10.1177/1744629518784154. Epub 2018 Jul 18.
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Crafting and retelling everyday lives--disabled people's contribution to bioethical concerns.
Matthews N, Ellem K, Chenoweth L.
Narrat Inq Bioeth. 2013 Winter;3(3):235-40. doi: 10.1353/nib.2013.0074.
Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3.
Piva TJ, Davern CM, Hall PM, Winterford CM, Ellem KA.
Int J Mol Sci. 2012;13(3):2650-75. doi: 10.3390/ijms13032650. Epub 2012 Feb 28.
Dendritic cell immunotherapy for stage IV melanoma.
O'Rourke MG, Johnson MK, Lanagan CM, See JL, O'Connor LE, Slater GJ, Thomas D, Lopez JA, Martinez NR, Ellem KA, Schmidt CW.
Melanoma Res. 2007 Oct;17(5):316-22.
Facultative or obligate anaerobic bacteria have the potential for multimodality therapy of solid tumours.
Wei MQ, Ellem KA, Dunn P, West MJ, Bai CX, Vogelstein B.
Eur J Cancer. 2007 Feb;43(3):490-6. Epub 2006 Nov 17. Review.
The development and characterization of an HEK293-derived cell line for use in an intratumoral cytokine delivery system.
Hamilton MJ, Huang QX, Li CL, Ellem KA.
Cell Transplant. 2006;15(4):343-50.
An extraordinarily high level of IL-15 expression by a cell line transduced with a modified BMGneo vector displays hypoxic upregulation.
Huang XQ, Hamilton MJ, Li CL, Schmidt C, Ellem KA.
Mol Biotechnol. 2006 May;33(1):49-56.
Immunological characteristics correlating with clinical response to immunotherapy in patients with advanced metastatic melanoma.
Marshall JA, Forster TH, Purdie DM, Lanagan CM, O'Connor LE, O'Rourke MG, Johnson MK, See JL, Ellem KA, Martinez NR, López JA, Schmidt CW.
Immunol Cell Biol. 2006 Jun;84(3):295-302.
The Development and Characterization of an HEK293-Derived Cell Line for Use in an Intratumoral Cytokine Delivery System.
Hamilton MJ, Huang QX, Li CL, Ellem KAO.
Cell Transplant. 2006 Apr;15(4):343-350. doi: 10.3727/000000006783981891.
Search for "weapons of mass destruction" for cancer -- immuno/ gene therapy comes of age.
Wei MQ, Metharom P, Ellem KA, Barth S.
Cell Mol Immunol. 2005 Oct;2(5):351-7. Review.
Gene transfer to dendritic cells induced a protective immunity against melanoma.
Metharom P, Ellem KA, Wei MQ.
Cell Mol Immunol. 2005 Aug;2(4):281-8.
The significance of controlled conditions in lentiviral vector titration and in the use of multiplicity of infection (MOI) for predicting gene transfer events.
Zhang B, Metharom P, Jullie H, Ellem KA, Cleghorn G, West MJ, Wei MQ.
Genet Vaccines Ther. 2004 Aug 4;2(1):6.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Pavey S, Johansson P, Packer L, Taylor J, Stark M, Pollock PM, Walker GJ, Boyle GM, Harper U, Cozzi SJ, Hansen K, Yudt L, Schmidt C, Hersey P, Ellem KA, O'Rourke MG, Parsons PG, Meltzer P, Ringnér M, Hayward NK.
Oncogene. 2004 May 20;23(23):4060-7.
Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine.
O'Rourke MG, Johnson M, Lanagan C, See J, Yang J, Bell JR, Slater GJ, Kerr BM, Crowe B, Purdie DM, Elliott SL, Ellem KA, Schmidt CW.
Cancer Immunol Immunother. 2003 Jun;52(6):387-95. Epub 2003 Apr 8.
Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells.
Ladhams A, Schmidt C, Sing G, Butterworth L, Fielding G, Tesar P, Strong R, Leggett B, Powell L, Maddern G, Ellem K, Cooksley G.
J Gastroenterol Hepatol. 2002 Aug;17(8):889-96.
Lentiviral vector-mediated tyrosinase-related protein 2 gene transfer to dendritic cells for the therapy of melanoma.
Metharom P, Ellem KA, Schmidt C, Wei MQ.
Hum Gene Ther. 2001 Dec 10;12(18):2203-13.
John Kerr and apoptosis.
O'Rourke MG, Ellem KA.
Med J Aust. 2000 Dec 4-18;173(11-12):616-7.
VP22 enhanced intercellular trafficking of HSV thymidine kinase reduced the level of ganciclovir needed to cause suicide cell death.
Liu CS, Kong B, Xia HH, Ellem KA, Wei MQ.
J Gene Med. 2001 Mar-Apr;3(2):145-52.
Development of disabled, replication-defective gene transfer vectors from the Jembrana disease virus, a new infectious agent of cattle.
Metharom P, Takyar S, Xia HQ, Ellem KA, Wilcox GE, Wei MQ.
Vet Microbiol. 2001 May 3;80(1):9-22.
Increased cell surface protease activity in UV-irradiated cells undergoing apoptosis.
Piva TJ, Davern CM, Winterford CM, Ellem KA.
Redox Rep. 2000;5(2-3):133-6.
Novel bovine lentiviral vectors based on Jembrana disease virus.
Metharom P, Takyar S, Xia HH, Ellem KA, Macmillan J, Shepherd RW, Wilcox GE, Wei MQ.
J Gene Med. 2000 May-Jun;2(3):176-85.
Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events.
De Souza CP, Ellem KA, Gabrielli BG.
Exp Cell Res. 2000 May 25;257(1):11-21.
Increased ecto-metallopeptidase activity in cells undergoing apoptosis.
Piva TJ, Davern CM, Francis KG, Chojnowski GM, Hall PM, Ellem KA.
J Cell Biochem. 2000 Jan;76(4):625-38.
Multiple splicing variants of cdc25B regulate G2/M progression.
Forrest AR, McCormack AK, DeSouza CP, Sinnamon JM, Tonks ID, Hayward NK, Ellem KA, Gabrielli BG.
Biochem Biophys Res Commun. 1999 Jul 5;260(2):510-5.
Tumor metastasis biopsy as a surrogate marker of response to melanoma immunotherapy.
Zehntner S, Townsend W, Parkes J, Schmidt C, Down M, Bell J, Mulligan R, O'Rourke M, Ellem K, Thomas R.
Pathology. 1999 May;31(2):116-22. Erratum in: Pathology 2000 Feb;32(1):following 64.
A cyclin D-Cdk4 activity required for G2 phase cell cycle progression is inhibited in ultraviolet radiation-induced G2 phase delay.
Gabrielli BG, Sarcevic B, Sinnamon J, Walker G, Castellano M, Wang XQ, Ellem KA.
J Biol Chem. 1999 May 14;274(20):13961-9.
Effect of UV irradiation on cell surface protease activity and amino acid uptake.
Piva TJ, Francis KG, Krause DR, Chojnowski GM, Ellem KA.
Mutat Res. 1998 Nov 9;422(1):55-67.
Involvement of p16CDKN2A in cell cycle delays after low dose UV irradiation.
Milligan A, Gabrielli BG, Clark JM, Hayward NK, Ellem KA.
Mutat Res. 1998 Nov 9;422(1):43-53.
The labyrinthine ways of cancer immunotherapy--T cell, tumor cell encounter: "how do I lose thee? Let me count the ways".
Ellem KA, Schmidt CW, Li CL, Misko I, Kelso A, Sing G, Macdonald G, O'Rourke MG.
Adv Cancer Res. 1998;75:203-49. Review. No abstract available.
Immunotherapy, including gene therapy, for metastatic melanoma.
O'Rourke MG, Schmidt CW, O'Rourke TR, Ellem KA.
Aust N Z J Surg. 1997 Dec;67(12):834-41. Review.
Hyperphosphorylation of the N-terminal domain of Cdc25 regulates activity toward cyclin B1/Cdc2 but not cyclin A/Cdk2.
Gabrielli BG, Clark JM, McCormack AK, Ellem KA.
J Biol Chem. 1997 Nov 7;272(45):28607-14.
Characterization and localization of mitochondrial oligopeptidase (MOP) (EC 3.4.24.16) activity in the human cervical adenocarcinoma cell line HeLa.
Krause DR, Piva TJ, Brown SB, Ellem KA.
J Cell Biochem. 1997 Sep 1;66(3):297-308.
Ultraviolet light-induced G2 phase cell cycle checkpoint blocks cdc25-dependent progression into mitosis.
Oncogene. 1997 Aug 14;15(7):749-58.
Multiple centrosomal microtubule organising centres and increased microtubule stability are early features of VP-16-induced apoptosis in CCRF-CEM cells.
Pittman S, Geyp M, Fraser M, Ellem K, Peaston A, Ireland C.
Leuk Res. 1997 Jun;21(6):491-9.
A case report: immune responses and clinical course of the first human use of granulocyte/macrophage-colony-stimulating-factor-transduced autologous melanoma cells for immunotherapy.
Ellem KA, O'Rourke MG, Johnson GR, Parry G, Misko IS, Schmidt CW, Parsons PG, Burrows SR, Cross S, Fell A, Li CL, Bell JR, Dubois PJ, Moss DJ, Good MF, Kelso A, Cohen LK, Dranoff G, Mulligan RC.
Cancer Immunol Immunother. 1997 Mar;44(1):10-20.
UVC activation of the HeLa cell membrane "TGF alpha ase," a metalloenzyme.
Piva TJ, Krause DR, Ellem KO.
J Cell Biochem. 1997 Mar 1;64(3):353-68.
Accumulation of p16CDKN2A in response to ultraviolet irradiation correlates with late S-G(2)-phase cell cycle delay.
Wang XQ, Gabrielli BG, Milligan A, Dickinson JL, Antalis TM, Ellem KA.
Cancer Res. 1996 Jun 1;56(11):2510-4.
In memoriam Peter F.L. Boreham (1942-1995).
Upcroft J, Ellem K, Upcroft P, McManus D.
Int J Parasitol. 1996 May;26(5):461-9. No abstract available.
Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells.
Gabrielli BG, De Souza CP, Tonks ID, Clark JM, Hayward NK, Ellem KA.
J Cell Sci. 1996 May;109 ( Pt 5):1081-93.
Peter F.L. Boreham (1942-1995).
Acta Trop. 1996 Feb;60(4):221-4. No abstract available.
Loss and shedding of surface markers from the leukemic myeloid monocytic line THP-1 induced to undergo apoptosis.
Brown SB, Kluck RM, Ellem KA.
J Cell Biochem. 1996 Feb;60(2):246-59.
Heterogeneity in the HeLa cell cycle response to UVC analyzed by the BrdUrd two-parameter method.
Wang XQ, Ellem KA.
Exp Cell Res. 1994 Jun;212(2):176-89.
Induction of cell surface peptidase activity: a global response to cell stress correlated with apoptosis.
J Cell Biochem. 1994 Mar;54(3):320-31.
The human cell cycle gene CDC25B is located at 20p13.
Lane SA, Baker E, Sutherland GR, Tonks I, Hayward N, Ellem K.
Genomics. 1993 Mar;15(3):693-4. No abstract available.
Low fluences of ultraviolet irradiation stimulate HeLa cell surface aminopeptidase and candidate "TGF alpha ase" activity.
Brown SB, Krause D, Ellem KA.
J Cell Biochem. 1993 Jan;51(1):102-15.
UV induction of transforming growth factor alpha in melanoma cell lines is a posttranslational event.
Chenevix-Trench G, Cullinan M, Ellem KA, Hayward NK.
J Cell Physiol. 1992 Aug;152(2):328-36.
Development of a sensitive peptidase assay: in search of cell associated proteases responsible for the cleavage of preproTGF alpha.
Brown SB, Krause D, Townsend E, Ellem KA.
J Cell Biochem. 1992 Apr;48(4):411-23.
UVC modulation of epidermal growth factor receptor number in HeLa S3 cells.
Ley KD, Ellem KA.
Carcinogenesis. 1992 Feb;13(2):183-7.
A monoclonal antibody raised against an undecapeptide sequence from human transforming growth factor alpha recognizes a hexapeptide epitope in mitotic centrosomes.
Ellem KA, Wilson MS, Fardoulys C, Dunstan A, Kemp BE, Geysen HM.
Lab Invest. 1990 Nov;63(5):690-7.
Gene expression in melanoma cell lines and cultured melanocytes: correlation between levels of c-src-1, c-myc and p53.
Chenevix-Trench G, Martin NG, Ellem KA.
Oncogene. 1990 Aug;5(8):1187-93.
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