Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 72

1.

Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.

Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, Lerch JP, Suh H, Glass CK, Muotri AR.

Transl Psychiatry. 2019 Jan 17;9(1):24. doi: 10.1038/s41398-018-0344-y.

2.

Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions.

Arbogast T, Razaz P, Ellegood J, McKinstry S, Erdin S, Currall B, Aneichyk T, Lerch JP, Qiu LR, Rodriguiz RM, Mark Henkelman R, Talkowski ME, Wetsel WC, Golzio C, Katsanis N.

Hum Mol Genet. 2018 Dec 26. doi: 10.1093/hmg/ddy436. [Epub ahead of print]

PMID:
30590535
3.

Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors.

Tsai PT, Rudolph S, Guo C, Ellegood J, Gibson JM, Schaeffer SM, Mogavero J, Lerch JP, Regehr W, Sahin M.

Cell Rep. 2018 Oct 9;25(2):357-367.e4. doi: 10.1016/j.celrep.2018.09.039.

4.

Effects of placental growth factor deficiency on behavior, neuroanatomy, and cerebrovasculature of mice.

Kay VR, Rätsep MT, Cahill LS, Hickman AF, Zavan B, Newport ME, Ellegood J, Laliberte CL, Reynolds JN, Carmeliet P, Tayade C, Sled JG, Croy BA.

Physiol Genomics. 2018 Oct 1;50(10):862-875. doi: 10.1152/physiolgenomics.00076.2018. Epub 2018 Aug 17.

PMID:
30118404
5.

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.

Jung H, Park H, Choi Y, Kang H, Lee E, Kweon H, Roh JD, Ellegood J, Choi W, Kang J, Rhim I, Choi SY, Bae M, Kim SG, Lee J, Chung C, Yoo T, Park H, Kim Y, Ha S, Um SM, Mo S, Kwon Y, Mah W, Bae YC, Kim H, Lerch JP, Paik SB, Kim E.

Nat Neurosci. 2018 Sep;21(9):1218-1228. doi: 10.1038/s41593-018-0208-z. Epub 2018 Aug 13.

PMID:
30104731
6.

Structural covariance of brain region volumes is associated with both structural connectivity and transcriptomic similarity.

Yee Y, Fernandes DJ, French L, Ellegood J, Cahill LS, Vousden DA, Spencer Noakes L, Scholz J, van Eede MC, Nieman BJ, Sled JG, Lerch JP.

Neuroimage. 2018 Oct 1;179:357-372. doi: 10.1016/j.neuroimage.2018.05.028. Epub 2018 May 18.

PMID:
29782994
7.

Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice.

Suetterlin P, Hurley S, Mohan C, Riegman KLH, Pagani M, Caruso A, Ellegood J, Galbusera A, Crespo-Enriquez I, Michetti C, Yee Y, Ellingford R, Brock O, Delogu A, Francis-West P, Lerch JP, Scattoni ML, Gozzi A, Fernandes C, Basson MA.

Cereb Cortex. 2018 Jun 1;28(6):2192-2206. doi: 10.1093/cercor/bhy058.

8.

Analysis of neuroanatomical differences in mice with genetically modified serotonin transporters assessed by structural magnetic resonance imaging.

Ellegood J, Yee Y, Kerr TM, Muller CL, Blakely RD, Henkelman RM, Veenstra-VanderWeele J, Lerch JP.

Mol Autism. 2018 Apr 10;9:24. doi: 10.1186/s13229-018-0210-z. eCollection 2018.

9.

Species-conserved SYNGAP1 phenotypes associated with neurodevelopmental disorders.

Kilinc M, Creson T, Rojas C, Aceti M, Ellegood J, Vaissiere T, Lerch JP, Rumbaugh G.

Mol Cell Neurosci. 2018 Sep;91:140-150. doi: 10.1016/j.mcn.2018.03.008. Epub 2018 Mar 24. Review.

PMID:
29580901
10.

Author Correction: Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice.

Stoodley CJ, D'Mello AM, Ellegood J, Jakkamsetti V, Liu P, Nebel MB, Gibson JM, Kelly E, Meng F, Cano CA, Pascual JM, Mostofsky SH, Lerch JP, Tsai PT.

Nat Neurosci. 2018 Jul;21(7):1016. doi: 10.1038/s41593-018-0096-2.

PMID:
29549317
11.

Behavioral and neuroanatomical approaches in models of neurodevelopmental disorders: opportunities for translation.

Silverman JL, Ellegood J.

Curr Opin Neurol. 2018 Apr;31(2):126-133. doi: 10.1097/WCO.0000000000000537.

PMID:
29493556
12.

Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling.

Richter M, Murtaza N, Scharrenberg R, White SH, Johanns O, Walker S, Yuen RKC, Schwanke B, Bedürftig B, Henis M, Scharf S, Kraus V, Dörk R, Hellmann J, Lindenmaier Z, Ellegood J, Hartung H, Kwan V, Sedlacik J, Fiehler J, Schweizer M, Lerch JP, Hanganu-Opatz IL, Morellini F, Scherer SW, Singh KK, Calderon de Anda F.

Mol Psychiatry. 2018 Feb 21. doi: 10.1038/s41380-018-0025-5. [Epub ahead of print]

PMID:
29467497
13.

Developmental social communication deficits in the Shank3 rat model of phelan-mcdermid syndrome and autism spectrum disorder.

Berg EL, Copping NA, Rivera JK, Pride MC, Careaga M, Bauman MD, Berman RF, Lein PJ, Harony-Nicolas H, Buxbaum JD, Ellegood J, Lerch JP, Wöhr M, Silverman JL.

Autism Res. 2018 Apr;11(4):587-601. doi: 10.1002/aur.1925. Epub 2018 Jan 29.

PMID:
29377611
14.

Shifting priorities: highly conserved behavioral and brain network adaptations to chronic stress across species.

Nikolova YS, Misquitta KA, Rocco BR, Prevot TD, Knodt AR, Ellegood J, Voineskos AN, Lerch JP, Hariri AR, Sibille E, Banasr M.

Transl Psychiatry. 2018 Jan 22;8(1):26. doi: 10.1038/s41398-017-0083-5.

15.

Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice.

Stoodley CJ, D'Mello AM, Ellegood J, Jakkamsetti V, Liu P, Nebel MB, Gibson JM, Kelly E, Meng F, Cano CA, Pascual JM, Mostofsky SH, Lerch JP, Tsai PT.

Nat Neurosci. 2017 Dec;20(12):1744-1751. doi: 10.1038/s41593-017-0004-1. Epub 2017 Oct 30. Erratum in: Nat Neurosci. 2018 Mar 16;:.

16.

Distinct cerebellar foliation anomalies in a CHD7 haploinsufficient mouse model of CHARGE syndrome.

Whittaker DE, Kasah S, Donovan APA, Ellegood J, Riegman KLH, Volk HA, McGonnell I, Lerch JP, Basson MA.

Am J Med Genet C Semin Med Genet. 2017 Dec;175(4). doi: 10.1002/ajmg.c.31595. Epub 2017 Nov 23.

17.

Foxp1 regulation of neonatal vocalizations via cortical development.

Usui N, Araujo DJ, Kulkarni A, Co M, Ellegood J, Harper M, Toriumi K, Lerch JP, Konopka G.

Genes Dev. 2017 Oct 15;31(20):2039-2055. doi: 10.1101/gad.305037.117. Epub 2017 Nov 14.

18.

Kctd13 deletion reduces synaptic transmission via increased RhoA.

Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-García IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM.

Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1.

19.

Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region.

Donovan APA, Yu T, Ellegood J, Riegman KLH, de Geus C, van Ravenswaaij-Arts C, Fernandes C, Lerch JP, Basson MA.

Front Neuroanat. 2017 Oct 4;11:86. doi: 10.3389/fnana.2017.00086. eCollection 2017.

20.

Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.

Copping NA, Christian SGB, Ritter DJ, Islam MS, Buscher N, Zolkowska D, Pride MC, Berg EL, LaSalle JM, Ellegood J, Lerch JP, Reiter LT, Silverman JL, Dindot SV.

Hum Mol Genet. 2017 Oct 15;26(20):3995-4010. doi: 10.1093/hmg/ddx289.

21.

Foxp1 in Forebrain Pyramidal Neurons Controls Gene Expression Required for Spatial Learning and Synaptic Plasticity.

Araujo DJ, Toriumi K, Escamilla CO, Kulkarni A, Anderson AG, Harper M, Usui N, Ellegood J, Lerch JP, Birnbaum SG, Tucker HO, Powell CM, Konopka G.

J Neurosci. 2017 Nov 8;37(45):10917-10931. doi: 10.1523/JNEUROSCI.1005-17.2017. Epub 2017 Oct 4.

22.

Spatial gene expression analysis of neuroanatomical differences in mouse models.

Fernandes DJ, Ellegood J, Askalan R, Blakely RD, Dicicco-Bloom E, Egan SE, Osborne LR, Powell CM, Raznahan A, Robins DM, Salter MW, Sengar AS, Veenstra-VanderWeele J, Henkelman RM, Lerch JP.

Neuroimage. 2017 Dec;163:220-230. doi: 10.1016/j.neuroimage.2017.08.065. Epub 2017 Sep 4.

PMID:
28882630
23.

Systemic inflammation combined with neonatal cerebellar haemorrhage aggravates long-term structural and functional outcomes in a mouse model.

Tremblay S, Pai A, Richter L, Vafaei R, Potluri P, Ellegood J, Lerch JP, Goldowitz D.

Brain Behav Immun. 2017 Nov;66:257-276. doi: 10.1016/j.bbi.2017.07.013. Epub 2017 Jul 27.

PMID:
28755859
24.

Repeated exposure to sucrose for procedural pain in mouse pups leads to long-term widespread brain alterations.

Tremblay S, Ranger M, Chau CMY, Ellegood J, Lerch JP, Holsti L, Goldowitz D, Grunau RE.

Pain. 2017 Aug;158(8):1586-1598. doi: 10.1097/j.pain.0000000000000961.

25.

Germline Chd8 haploinsufficiency alters brain development in mouse.

Gompers AL, Su-Feher L, Ellegood J, Copping NA, Riyadh MA, Stradleigh TW, Pride MC, Schaffler MD, Wade AA, Catta-Preta R, Zdilar I, Louis S, Kaushik G, Mannion BJ, Plajzer-Frick I, Afzal V, Visel A, Pennacchio LA, Dickel DE, Lerch JP, Crawley JN, Zarbalis KS, Silverman JL, Nord AS.

Nat Neurosci. 2017 Aug;20(8):1062-1073. doi: 10.1038/nn.4592. Epub 2017 Jun 26.

26.

Neuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes.

Allemang-Grand R, Ellegood J, Spencer Noakes L, Ruston J, Justice M, Nieman BJ, Lerch JP.

Mol Autism. 2017 Jun 26;8:32. doi: 10.1186/s13229-017-0138-8. eCollection 2017.

27.

Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication.

Kishimoto K, Nomura J, Ellegood J, Fukumoto K, Lerch JP, Moreno-De-Luca D, Bourgeron T, Tamada K, Takumi T.

Genes Cells. 2017 May;22(5):436-451. doi: 10.1111/gtc.12487. Epub 2017 Mar 29.

28.

Prenatal β-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors.

Belinson H, Nakatani J, Babineau BA, Birnbaum RY, Ellegood J, Bershteyn M, McEvilly RJ, Long JM, Willert K, Klein OD, Ahituv N, Lerch JP, Rosenfeld MG, Wynshaw-Boris A.

Mol Psychiatry. 2016 Oct;21(10):1417-33. doi: 10.1038/mp.2015.207. Epub 2016 Feb 2.

29.

Regional brain volumes changes in adult male FMR1-KO mouse on the FVB strain.

Lai JK, Lerch JP, Doering LC, Foster JA, Ellegood J.

Neuroscience. 2016 Mar 24;318:12-21. doi: 10.1016/j.neuroscience.2016.01.021. Epub 2016 Jan 12.

PMID:
26794591
30.

Deep brain stimulation of the ventromedial prefrontal cortex causes reorganization of neuronal processes and vasculature.

Chakravarty MM, Hamani C, Martinez-Canabal A, Ellegood J, Laliberté C, Nobrega JN, Sankar T, Lozano AM, Frankland PW, Lerch JP.

Neuroimage. 2016 Jan 15;125:422-427. doi: 10.1016/j.neuroimage.2015.10.049. Epub 2015 Oct 23.

PMID:
26525655
31.

Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism.

Ellegood J, Crawley JN.

Neurotherapeutics. 2015 Jul;12(3):521-33. doi: 10.1007/s13311-015-0360-z. Review.

32.

Neuroanatomical Phenotypes Are Consistent With Autism-Like Behavioral Phenotypes in the 15q11-13 Duplication Mouse Model.

Ellegood J, Nakai N, Nakatani J, Henkelman M, Takumi T, Lerch J.

Autism Res. 2015 Oct;8(5):545-55. doi: 10.1002/aur.1469. Epub 2015 Mar 7.

PMID:
25755142
33.

Loss of T cells influences sex differences in behavior and brain structure.

Rilett KC, Friedel M, Ellegood J, MacKenzie RN, Lerch JP, Foster JA.

Brain Behav Immun. 2015 May;46:249-60. doi: 10.1016/j.bbi.2015.02.016. Epub 2015 Feb 26.

PMID:
25725160
34.

3D visualization of the regional differences.

Ellegood J, Anagnostou E, Babineau BA, Crawley JN, Lin L, Genestine M, DiCicco-Bloom E, Lai JK, Foster JA, Peñagarikano O, Geschwind DH, Pacey LK, Hampson DR, Laliberté CL, Mills AA, Tam E, Osborne LR, Kouser M, Espinosa-Becerra F, Xuan Z, Powell CM, Raznahan A, Robins DM, Nakai N, Nakatani J, Takumi T, van Eede MC, Kerr TM, Muller C, Blakely RD, Veenstra-VanderWeele J, Henkelman RM, Lerch JP.

Mol Psychiatry. 2015 Feb;20(1):1. doi: 10.1038/mp.2014.168. No abstract available.

35.

Altered brain development in an early-onset murine model of Alzheimer's disease.

Allemang-Grand R, Scholz J, Ellegood J, Cahill LS, Laliberté C, Fraser PE, Josselyn SA, Sled JG, Lerch JP.

Neurobiol Aging. 2015 Feb;36(2):638-47. doi: 10.1016/j.neurobiolaging.2014.08.032. Epub 2014 Sep 6.

PMID:
25311279
36.

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity.

Ellegood J, Anagnostou E, Babineau BA, Crawley JN, Lin L, Genestine M, DiCicco-Bloom E, Lai JK, Foster JA, Peñagarikano O, Geschwind DH, Pacey LK, Hampson DR, Laliberté CL, Mills AA, Tam E, Osborne LR, Kouser M, Espinosa-Becerra F, Xuan Z, Powell CM, Raznahan A, Robins DM, Nakai N, Nakatani J, Takumi T, van Eede MC, Kerr TM, Muller C, Blakely RD, Veenstra-VanderWeele J, Henkelman RM, Lerch JP.

Mol Psychiatry. 2015 Feb;20(1):118-25. doi: 10.1038/mp.2014.98. Epub 2014 Sep 9.

37.

Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome.

Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dolen G, Bader PL, Grueter BA, Goold C, Fisher E, Clifford K, Rengarajan P, Kalikhman D, Loureiro D, Saw NL, Zhengqui Z, Miller MA, Lerch JP, Henkelman M, Shamloo M, Malenka RC, Crawley JN, Dolmetsch RE.

Cell Rep. 2014 May 22;7(4):1077-1092. doi: 10.1016/j.celrep.2014.03.036. Epub 2014 May 1.

38.

A highly specific pattern of volumetric brain changes due to 22q11.2 deletions in both mice and humans.

Ellegood J, Markx S, Lerch JP, Steadman PE, Genç C, Provenzano F, Kushner SA, Henkelman RM, Karayiorgou M, Gogos JA.

Mol Psychiatry. 2014 Jan;19(1):6. doi: 10.1038/mp.2013.179. No abstract available.

PMID:
24362540
39.

A gestational ketogenic diet alters maternal metabolic status as well as offspring physiological growth and brain structure in the neonatal mouse.

Sussman D, Ellegood J, Henkelman M.

BMC Pregnancy Childbirth. 2013 Oct 29;13:198. doi: 10.1186/1471-2393-13-198.

40.

Genetic effects on cerebellar structure across mouse models of autism using a magnetic resonance imaging atlas.

Steadman PE, Ellegood J, Szulc KU, Turnbull DH, Joyner AL, Henkelman RM, Lerch JP.

Autism Res. 2014 Feb;7(1):124-37. doi: 10.1002/aur.1344. Epub 2013 Oct 22.

41.

Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion.

Ellegood J, Markx S, Lerch JP, Steadman PE, Genç C, Provenzano F, Kushner SA, Henkelman RM, Karayiorgou M, Gogos JA.

Mol Psychiatry. 2014 Jan;19(1):99-107. doi: 10.1038/mp.2013.112. Epub 2013 Sep 3.

42.

Vertebrate intersectin1 is repurposed to facilitate cortical midline connectivity and higher order cognition.

Sengar AS, Ellegood J, Yiu AP, Wang H, Wang W, Juneja SC, Lerch JP, Josselyn SA, Henkelman RM, Salter MW, Egan SE.

J Neurosci. 2013 Feb 27;33(9):4055-65. doi: 10.1523/JNEUROSCI.4428-12.2013.

43.

Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging.

Ellegood J, Babineau BA, Henkelman RM, Lerch JP, Crawley JN.

Neuroimage. 2013 Apr 15;70:288-300. doi: 10.1016/j.neuroimage.2012.12.029. Epub 2012 Dec 26.

44.

Neuroanatomical Assessment of the Integrin β3 Mouse Model Related to Autism and the Serotonin System Using High Resolution MRI.

Ellegood J, Henkelman RM, Lerch JP.

Front Psychiatry. 2012 Apr 26;3:37. doi: 10.3389/fpsyt.2012.00037. eCollection 2012.

45.

Preparation of fixed mouse brains for MRI.

Cahill LS, Laliberté CL, Ellegood J, Spring S, Gleave JA, Eede MC, Lerch JP, Henkelman RM.

Neuroimage. 2012 Apr 2;60(2):933-9. doi: 10.1016/j.neuroimage.2012.01.100. Epub 2012 Jan 28.

PMID:
22305951
46.

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism.

Horev G, Ellegood J, Lerch JP, Son YE, Muthuswamy L, Vogel H, Krieger AM, Buja A, Henkelman RM, Wigler M, Mills AA.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17076-81. doi: 10.1073/pnas.1114042108. Epub 2011 Oct 3.

47.

Brain abnormalities in a Neuroligin3 R451C knockin mouse model associated with autism.

Ellegood J, Lerch JP, Henkelman RM.

Autism Res. 2011 Oct;4(5):368-76. doi: 10.1002/aur.215. Epub 2011 Aug 31.

PMID:
21882360
48.

Considerations for measuring the fractional anisotropy of metabolites with diffusion tensor spectroscopy.

Ellegood J, Hanstock CC, Beaulieu C.

NMR Biomed. 2011 Apr;24(3):270-80. doi: 10.1002/nbm.1586. Epub 2010 Oct 6.

PMID:
20925126
49.

Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging.

Ellegood J, Pacey LK, Hampson DR, Lerch JP, Henkelman RM.

Neuroimage. 2010 Nov 15;53(3):1023-9. doi: 10.1016/j.neuroimage.2010.03.038. Epub 2010 Mar 19.

PMID:
20304074
50.

Anisotropic diffusion of metabolites in peripheral nerve using diffusion weighted magnetic resonance spectroscopy at ultra-high field.

Ellegood J, McKay RT, Hanstock CC, Beaulieu C.

J Magn Reson. 2007 Jan;184(1):20-8. Epub 2006 Oct 5.

PMID:
17027305

Supplemental Content

Loading ...
Support Center