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Items: 5

1.

Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment.

Ellegaard AM, Dehlendorff C, Vind AC, Anand A, Cederkvist L, Petersen NHT, Nylandsted J, Stenvang J, Mellemgaard A, Østerlind K, Friis S, Jäättelä M.

EBioMedicine. 2016 Jul;9:130-139. doi: 10.1016/j.ebiom.2016.06.013. Epub 2016 Jun 7.

2.

Visualizing Lysosomal Membrane Permeabilization by Fluorescent Dextran Release.

Ellegaard AM, Jäättelä M, Nylandsted J.

Cold Spring Harb Protoc. 2015 Oct 1;2015(10):900-3. doi: 10.1101/pdb.prot086173.

PMID:
26430253
3.

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay.

Aits S, Kricker J, Liu B, Ellegaard AM, Hämälistö S, Tvingsholm S, Corcelle-Termeau E, Høgh S, Farkas T, Holm Jonassen A, Gromova I, Mortensen M, Jäättelä M.

Autophagy. 2015;11(8):1408-24. doi: 10.1080/15548627.2015.1063871.

4.

Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.

Petersen NH, Olsen OD, Groth-Pedersen L, Ellegaard AM, Bilgin M, Redmer S, Ostenfeld MS, Ulanet D, Dovmark TH, Lønborg A, Vindeløv SD, Hanahan D, Arenz C, Ejsing CS, Kirkegaard T, Rohde M, Nylandsted J, Jäättelä M.

Cancer Cell. 2013 Sep 9;24(3):379-93. doi: 10.1016/j.ccr.2013.08.003.

5.

Sunitinib and SU11652 inhibit acid sphingomyelinase, destabilize lysosomes, and inhibit multidrug resistance.

Ellegaard AM, Groth-Pedersen L, Oorschot V, Klumperman J, Kirkegaard T, Nylandsted J, Jäättelä M.

Mol Cancer Ther. 2013 Oct;12(10):2018-30. doi: 10.1158/1535-7163.MCT-13-0084. Epub 2013 Aug 6.

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