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Items: 5


Activation loop phosphorylation of ERK3 is important for its kinase activity and ability to promote lung cancer cell invasiveness.

Elkhadragy L, Alsaran H, Morel M, Long W.

J Biol Chem. 2018 Oct 19;293(42):16193-16205. doi: 10.1074/jbc.RA118.003699. Epub 2018 Aug 30.


L290P/V mutations increase ERK3's cytoplasmic localization and migration/invasion-promoting capability in cancer cells.

Alsaran H, Elkhadragy L, Shakya A, Long W.

Sci Rep. 2017 Nov 3;7(1):14979. doi: 10.1038/s41598-017-15135-9.


A regulatory BMI1/let-7i/ERK3 pathway controls the motility of head and neck cancer cells.

Elkhadragy L, Chen M, Miller K, Yang MH, Long W.

Mol Oncol. 2017 Feb;11(2):194-207. doi: 10.1002/1878-0261.12021. Epub 2017 Jan 12.


A Repertoire of MicroRNAs Regulates Cancer Cell Starvation by Targeting Phospholipase D in a Feedback Loop That Operates Maximally in Cancer Cells.

Fite K, Elkhadragy L, Gomez-Cambronero J.

Mol Cell Biol. 2016 Jan 19;36(7):1078-89. doi: 10.1128/MCB.00711-15.


ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells.

Bian K, Muppani NR, Elkhadragy L, Wang W, Zhang C, Chen T, Jung S, Seternes OM, Long W.

Oncotarget. 2016 Feb 9;7(6):6665-75. doi: 10.18632/oncotarget.6682.

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