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Items: 6


Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.

Zhang Y, Xiong S, Liu B, Pant V, Celii F, Chau G, Elizondo-Fraire AC, Yang P, You MJ, El-Naggar AK, Navin NE, Lozano G.

Nat Commun. 2018 Sep 27;9(1):3953. doi: 10.1038/s41467-018-06146-9.


Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.

Xiong S, Tu H, Kollareddy M, Pant V, Li Q, Zhang Y, Jackson JG, Suh YA, Elizondo-Fraire AC, Yang P, Chau G, Tashakori M, Wasylishen AR, Ju Z, Solomon H, Rotter V, Liu B, El-Naggar AK, Donehower LA, Martinez LA, Lozano G.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11145-50. doi: 10.1073/pnas.1404139111. Epub 2014 Jul 14.


Multiple stress signals activate mutant p53 in vivo.

Suh YA, Post SM, Elizondo-Fraire AC, Maccio DR, Jackson JG, El-Naggar AK, Van Pelt C, Terzian T, Lozano G.

Cancer Res. 2011 Dec 1;71(23):7168-75. doi: 10.1158/0008-5472.CAN-11-0459. Epub 2011 Oct 7.


Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.

Xiong S, Van Pelt CS, Elizondo-Fraire AC, Fernandez-Garcia B, Lozano G.

Circulation. 2007 Jun 12;115(23):2925-30. Epub 2007 May 28.


Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.

Xiong S, Van Pelt CS, Elizondo-Fraire AC, Liu G, Lozano G.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3226-31. Epub 2006 Feb 21.


Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.

Grier JD, Xiong S, Elizondo-Fraire AC, Parant JM, Lozano G.

Mol Cell Biol. 2006 Jan;26(1):192-8.

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