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Items: 1 to 50 of 69

1.

Optoelectronic control of single cells using organic photocapacitors.

Jakešová M, Silverå Ejneby M, Đerek V, Schmidt T, Gryszel M, Brask J, Schindl R, Simon DT, Berggren M, Elinder F, Głowacki ED.

Sci Adv. 2019 Apr 5;5(4):eaav5265. doi: 10.1126/sciadv.aav5265. eCollection 2019 Apr.

2.

Alpha and omega in potassium-channel opening.

Elinder F.

Acta Physiol (Oxf). 2019 Feb;225(2):e13240. doi: 10.1111/apha.13240. Epub 2018 Dec 31. No abstract available.

PMID:
30554471
3.

Biaryl sulfonamide motifs up- or down-regulate ion channel activity by activating voltage sensors.

Liin SI, Lund PE, Larsson JE, Brask J, Wallner B, Elinder F.

J Gen Physiol. 2018 Aug 6;150(8):1215-1230. doi: 10.1085/jgp.201711942. Epub 2018 Jul 12.

4.

Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid.

Silverå Ejneby M, Wu X, Ottosson NE, Münger EP, Lundström I, Konradsson P, Elinder F.

J Gen Physiol. 2018 May 7;150(5):731-750. doi: 10.1085/jgp.201711965. Epub 2018 Apr 6.

5.

A drug pocket at the lipid bilayer-potassium channel interface.

Ottosson NE, Silverå Ejneby M, Wu X, Yazdi S, Konradsson P, Lindahl E, Elinder F.

Sci Adv. 2017 Oct 25;3(10):e1701099. doi: 10.1126/sciadv.1701099. eCollection 2017 Oct.

6.

Neural inhibition can explain negative BOLD responses: A mechanistic modelling and fMRI study.

Sten S, Lundengård K, Witt ST, Cedersund G, Elinder F, Engström M.

Neuroimage. 2017 Sep;158:219-231. doi: 10.1016/j.neuroimage.2017.07.002. Epub 2017 Jul 4.

PMID:
28687518
7.

Isopimaric acid - a multi-targeting ion channel modulator reducing excitability and arrhythmicity in a spontaneously beating mouse atrial cell line.

Salari S, Silverå Ejneby M, Brask J, Elinder F.

Acta Physiol (Oxf). 2018 Jan;222(1). doi: 10.1111/apha.12895. Epub 2017 Jun 9.

8.

Actions and Mechanisms of Polyunsaturated Fatty Acids on Voltage-Gated Ion Channels.

Elinder F, Liin SI.

Front Physiol. 2017 Feb 6;8:43. doi: 10.3389/fphys.2017.00043. eCollection 2017. Review.

9.

Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1.

Elinder F, Madeja M, Zeberg H, Århem P.

Biophys J. 2016 Oct 18;111(8):1679-1691. doi: 10.1016/j.bpj.2016.08.043.

10.

Mechanistic Mathematical Modeling Tests Hypotheses of the Neurovascular Coupling in fMRI.

Lundengård K, Cedersund G, Sten S, Leong F, Smedberg A, Elinder F, Engström M.

PLoS Comput Biol. 2016 Jun 16;12(6):e1004971. doi: 10.1371/journal.pcbi.1004971. eCollection 2016 Jun.

11.

Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.

Conti L, Renhorn J, Gabrielsson A, Turesson F, Liin SI, Lindahl E, Elinder F.

Sci Rep. 2016 Jun 9;6:27562. doi: 10.1038/srep27562.

12.

Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes.

Liin SI, Karlsson U, Bentzen BH, Schmitt N, Elinder F.

Acta Physiol (Oxf). 2016 Sep;218(1):28-37. doi: 10.1111/apha.12663. Epub 2016 Mar 23.

13.

The Molecular Basis of Polyunsaturated Fatty Acid Interactions with the Shaker Voltage-Gated Potassium Channel.

Yazdi S, Stein M, Elinder F, Andersson M, Lindahl E.

PLoS Comput Biol. 2016 Jan 11;12(1):e1004704. doi: 10.1371/journal.pcbi.1004704. eCollection 2016 Jan.

14.

Resin-acid derivatives as potent electrostatic openers of voltage-gated K channels and suppressors of neuronal excitability.

Ottosson NE, Wu X, Nolting A, Karlsson U, Lund PE, Ruda K, Svensson S, Konradsson P, Elinder F.

Sci Rep. 2015 Aug 24;5:13278. doi: 10.1038/srep13278.

15.

Electronic polymers in lipid membranes.

Johansson PK, Jullesson D, Elfwing A, Liin SI, Musumeci C, Zeglio E, Elinder F, Solin N, Inganäs O.

Sci Rep. 2015 Jun 10;5:11242. doi: 10.1038/srep11242.

16.

Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel.

Liin SI, Silverå Ejneby M, Barro-Soria R, Skarsfeldt MA, Larsson JE, Starck Härlin F, Parkkari T, Bentzen BH, Schmitt N, Larsson HP, Elinder F.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5714-9. doi: 10.1073/pnas.1503488112. Epub 2015 Apr 21.

17.

A voltage dependent non-inactivating Na+ channel activated during apoptosis in Xenopus oocytes.

Englund UH, Gertow J, Kågedal K, Elinder F.

PLoS One. 2014 Feb 28;9(2):e88381. doi: 10.1371/journal.pone.0088381. eCollection 2014.

18.

Drug-induced ion channel opening tuned by the voltage sensor charge profile.

Ottosson NE, Liin SI, Elinder F.

J Gen Physiol. 2014 Feb;143(2):173-82. doi: 10.1085/jgp.201311087. Epub 2014 Jan 13.

19.

The conserved phenylalanine in the K+ channel voltage-sensor domain creates a barrier with unidirectional effects.

Schwaiger CS, Liin SI, Elinder F, Lindahl E.

Biophys J. 2013 Jan 8;104(1):75-84. doi: 10.1016/j.bpj.2012.11.3827. Epub 2013 Jan 8.

20.

The free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain.

Schwaiger CS, Börjesson SI, Hess B, Wallner B, Elinder F, Lindahl E.

PLoS One. 2012;7(10):e45880. doi: 10.1371/journal.pone.0045880. Epub 2012 Oct 19.

21.

Dampening of hyperexcitability in CA1 pyramidal neurons by polyunsaturated fatty acids acting on voltage-gated ion channels.

Tigerholm J, Börjesson SI, Lundberg L, Elinder F, Fransén E.

PLoS One. 2012;7(9):e44388. doi: 10.1371/journal.pone.0044388. Epub 2012 Sep 25.

22.

Exploration of human, rat, and rabbit embryonic cardiomyocytes suggests K-channel block as a common teratogenic mechanism.

Danielsson C, Brask J, Sköld AC, Genead R, Andersson A, Andersson U, Stockling K, Pehrson R, Grinnemo KH, Salari S, Hellmold H, Danielsson B, Sylvén C, Elinder F.

Cardiovasc Res. 2013 Jan 1;97(1):23-32. doi: 10.1093/cvr/cvs296. Epub 2012 Sep 20.

PMID:
22997158
23.

Tracking a complete voltage-sensor cycle with metal-ion bridges.

Henrion U, Renhorn J, Börjesson SI, Nelson EM, Schwaiger CS, Bjelkmar P, Wallner B, Lindahl E, Elinder F.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8552-7. doi: 10.1073/pnas.1116938109. Epub 2012 Apr 25.

24.

Intracellular K+ concentration decrease is not obligatory for apoptosis.

Börjesson SI, Englund UH, Asif MH, Willander M, Elinder F.

J Biol Chem. 2011 Nov 18;286(46):39823-8. doi: 10.1074/jbc.M111.262725. Epub 2011 Sep 26.

25.

An electrostatic potassium channel opener targeting the final voltage sensor transition.

Börjesson SI, Elinder F.

J Gen Physiol. 2011 Jun;137(6):563-77. doi: 10.1085/jgp.201110599.

26.

Functionalized ZnO nanorod-based selective magnesium ion sensor for intracellular measurements.

Asif MH, Ali SM, Nur O, Willander M, Englund UH, Elinder F.

Biosens Bioelectron. 2010 Nov 15;26(3):1118-23. doi: 10.1016/j.bios.2010.08.017. Epub 2010 Aug 20.

PMID:
20846846
27.

Growth and Structure of ZnO Nanorods on a Sub-Micrometer Glass Pipette and Their Application as Intracellular Potentiometric Selective Ion Sensors.

Asif MH, Nur O, Willander M, Strålfors P, Brännmark C, Elinder F, Englund UH, Lu J, Hultman L.

Materials (Basel). 2010 Sep 9;3(9):4657-4667. doi: 10.3390/ma3094657.

28.

Functionalised ZnO-nanorod-based selective electrochemical sensor for intracellular glucose.

Asif MH, Ali SM, Nur O, Willander M, Brännmark C, Strålfors P, Englund UH, Elinder F, Danielsson B.

Biosens Bioelectron. 2010 Jun 15;25(10):2205-11. doi: 10.1016/j.bios.2010.02.025. Epub 2010 Mar 3.

PMID:
20303253
29.

Electrostatic tuning of cellular excitability.

Börjesson SI, Parkkari T, Hammarström S, Elinder F.

Biophys J. 2010 Feb 3;98(3):396-403. doi: 10.1016/j.bpj.2009.10.026.

30.

Oxaliplatin neurotoxicity--no general ion channel surface-charge effect.

Broomand A, Jerremalm E, Yachnin J, Ehrsson H, Elinder F.

J Negat Results Biomed. 2009 Jan 12;8:2. doi: 10.1186/1477-5751-8-2.

31.

Structure, function, and modification of the voltage sensor in voltage-gated ion channels.

Börjesson SI, Elinder F.

Cell Biochem Biophys. 2008;52(3):149-74. doi: 10.1007/s12013-008-9032-5. Epub 2008 Nov 7. Review.

PMID:
18989792
32.

Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells.

Akanda N, Tofighi R, Brask J, Tamm C, Elinder F, Ceccatelli S.

Cell Cycle. 2008 Oct;7(20):3225-34. Epub 2008 Oct 20.

PMID:
18927501
33.

Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics.

Nilsson J, Madeja M, Elinder F, Arhem P.

Biophys J. 2008 Dec;95(11):5138-52. doi: 10.1529/biophysj.108.130518. Epub 2008 Sep 12.

34.

Large-scale movement within the voltage-sensor paddle of a potassium channel-support for a helical-screw motion.

Broomand A, Elinder F.

Neuron. 2008 Sep 11;59(5):770-7. doi: 10.1016/j.neuron.2008.07.008.

35.

Lipoelectric modification of ion channel voltage gating by polyunsaturated fatty acids.

Börjesson SI, Hammarström S, Elinder F.

Biophys J. 2008 Sep;95(5):2242-53. doi: 10.1529/biophysj.108.130757. Epub 2008 May 23.

36.

Polyunsaturated fatty acids and cerebrospinal fluid from children on the ketogenic diet open a voltage-gated K channel: a putative mechanism of antiseizure action.

Xu XP, Erichsen D, Börjesson SI, Dahlin M, Amark P, Elinder F.

Epilepsy Res. 2008 Jul;80(1):57-66. doi: 10.1016/j.eplepsyres.2008.03.013. Epub 2008 May 2.

PMID:
18448313
37.

A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation.

Klement G, Nilsson J, Arhem P, Elinder F.

Biophys J. 2008 Apr 15;94(8):3014-22. doi: 10.1529/biophysj.107.119842. Epub 2008 Jan 11.

38.

Kinetic relationship between the voltage sensor and the activation gate in spHCN channels.

Bruening-Wright A, Elinder F, Larsson HP.

J Gen Physiol. 2007 Jul;130(1):71-81.

39.

On the opening of voltage-gated ion channels.

Elinder F, Nilsson J, Arhem P.

Physiol Behav. 2007 Sep 10;92(1-2):1-7. Epub 2007 May 25. Review.

PMID:
17585963
40.

Electrostatic domino effect in the Shaker K channel turret.

Broomand A, Osterberg F, Wardi T, Elinder F.

Biophys J. 2007 Oct 1;93(7):2307-14. Epub 2007 Jun 1.

41.

Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels.

Elinder F, Männikkö R, Pandey S, Larsson HP.

J Physiol. 2006 Sep 1;575(Pt 2):417-31. Epub 2006 Jun 15.

42.

Biophysical properties of the apoptosis-inducing plasma membrane voltage-dependent anion channel.

Akanda N, Elinder F.

Biophys J. 2006 Jun 15;90(12):4405-17. Epub 2006 Mar 31.

43.

Opening of plasma membrane voltage-dependent anion channels (VDAC) precedes caspase activation in neuronal apoptosis induced by toxic stimuli.

Elinder F, Akanda N, Tofighi R, Shimizu S, Tsujimoto Y, Orrenius S, Ceccatelli S.

Cell Death Differ. 2005 Aug;12(8):1134-40.

44.

Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties.

Männikkö R, Pandey S, Larsson HP, Elinder F.

J Gen Physiol. 2005 Mar;125(3):305-26. Epub 2005 Feb 14.

45.

Metal ion effects on ion channel gating.

Elinder F, Arhem P.

Q Rev Biophys. 2003 Nov;36(4):373-427. Review.

PMID:
15267168
46.

Molecular movement of the voltage sensor in a K channel.

Broomand A, Männikkö R, Larsson HP, Elinder F.

J Gen Physiol. 2003 Dec;122(6):741-8. Epub 2003 Nov 10.

47.

Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.

Männikkö R, Elinder F, Larsson HP.

Nature. 2002 Oct 24;419(6909):837-41.

PMID:
12397358
48.

Na channel kinetics: developing models from non-stationary current fluctuations by analytic methods.

Blomberg C, Elinder F, Arhem P.

Biosystems. 2001 Sep-Oct;62(1-3):29-43.

PMID:
11595317
49.
50.

S4 charges move close to residues in the pore domain during activation in a K channel.

Elinder F, Männikkö R, Larsson HP.

J Gen Physiol. 2001 Jul;118(1):1-10.

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