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FGF21 gene therapy as treatment for obesity and insulin resistance.

Jimenez V, Jambrina C, Casana E, Sacristan V, Muñoz S, Darriba S, Rodó J, Mallol C, Garcia M, León X, Marcó S, Ribera A, Elias I, Casellas A, Grass I, Elias G, Ferré T, Motas S, Franckhauser S, Mulero F, Navarro M, Haurigot V, Ruberte J, Bosch F.

EMBO Mol Med. 2018 Aug;10(8). pii: e8791. doi: 10.15252/emmm.201708791.


Phase I results of a phase I/II study of weekly nab-paclitaxel in paediatric patients with recurrent/refractory solid tumours: A collaboration with innovative therapies for children with cancer.

Moreno L, Casanova M, Chisholm JC, Berlanga P, Chastagner PB, Baruchel S, Amoroso L, Gallego Melcón S, Gerber NU, Bisogno G, Fagioli F, Geoerger B, Glade Bender JL, Aerts I, Bergeron C, Hingorani P, Elias I, Simcock M, Ferrara S, Le Bruchec Y, Slepetis R, Chen N, Vassal G.

Eur J Cancer. 2018 Sep;100:27-34. doi: 10.1016/j.ejca.2018.05.002. Epub 2018 Jun 21.


Synchronous ipsilateral renal cell carcinoma and transitional cell carcinoma of the renal pelvic with complete remission of TCC after neoadjuvant chemotherapy.

Safadi A, Elias I, Visoki A, Zick A, Schwalb S, Katz R.

Urol Case Rep. 2018 May 4;19:28-30. doi: 10.1016/j.eucr.2018.05.003. eCollection 2018 Jul. No abstract available.


Cost-effectiveness analysis of sensor-augmented pump therapy with low glucose-suspend in patients with type 1 diabetes mellitus and high risk of hypoglycemia in Spain.

Conget I, Martín-Vaquero P, Roze S, Elías I, Pineda C, Álvarez M, Delbaere A, Ampudia-Blasco FJ.

Endocrinol Diabetes Nutr. 2018 Aug - Sep;65(7):380-386. doi: 10.1016/j.endinu.2018.03.008. Epub 2018 May 19. English, Spanish.


[Consumption of free sugars and excess weight in infants. A longitudinal study].

Jardí C, Aranda N, Bedmar C, Ribot B, Elias I, Aparicio E, Arija V; Grupo investigador DeFensas.

An Pediatr (Barc). 2018 May 14. pii: S1695-4033(18)30153-X. doi: 10.1016/j.anpedi.2018.03.018. [Epub ahead of print] Spanish.


Multiple sclerosis risk perception and acceptance for Brazilian patients.

Bichuetti DB, Franco CA, Elias I, Mendonça ACR, Carvalho LFD, Diniz DS, Tur C, Tintoré M, Oliveira EML.

Arq Neuropsiquiatr. 2018 Jan;76(1):6-12. doi: 10.1590/0004-282X20170167.


Budget impact of continuous subcutaneous insulin infusion therapy in patients with type 1 diabetes who experience severe recurrent hypoglycemic episodes in Spain.

Giménez M, Elías I, Álvarez M, Quirós C, Conget I.

Endocrinol Diabetes Nutr. 2017 Aug - Sep;64(7):377-383. doi: 10.1016/j.endinu.2017.04.006. Epub 2017 Jun 7. English, Spanish.


BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue.

Hoffmann JM, Grünberg JR, Church C, Elias I, Palsdottir V, Jansson JO, Bosch F, Hammarstedt A, Hedjazifar S, Smith U.

Cell Rep. 2017 Aug 1;20(5):1038-1049. doi: 10.1016/j.celrep.2017.07.020.


Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs.

Jaén ML, Vilà L, Elias I, Jimenez V, Rodó J, Maggioni L, Ruiz-de Gopegui R, Garcia M, Muñoz S, Callejas D, Ayuso E, Ferré T, Grifoll I, Andaluz A, Ruberte J, Haurigot V, Bosch F.

Mol Ther Methods Clin Dev. 2017 Apr 5;6:1-7. doi: 10.1016/j.omtm.2017.03.008. eCollection 2017 Sep 15.


AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance.

Vilà L, Roca C, Elias I, Casellas A, Lage R, Franckhauser S, Bosch F.

Mol Ther Methods Clin Dev. 2016 Nov 16;5:16072. eCollection 2016.


The Cost of Psoriasis and Psoriatic Arthritis in 5 European Countries: A Systematic Review.

Burgos-Pol R, Martínez-Sesmero JM, Ventura-Cerdá JM, Elías I, Caloto MT, Casado MÁ.

Actas Dermosifiliogr. 2016 Sep;107(7):577-90. doi: 10.1016/ Epub 2016 Jun 15. Review. English, Spanish.


ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.

Elias I, Ferré T, Vilà L, Muñoz S, Casellas A, Garcia M, Molas M, Agudo J, Roca C, Ruberte J, Bosch F, Franckhauser S.

Diabetes. 2016 Aug;65(8):2139-50. doi: 10.2337/db16-0040. Epub 2016 May 3.


Cost-effectiveness analysis of apixaban compared to low-molecularweight heparins and vitamin k antagonists for treatment and secondary prevention of venous thromboembolism.

Elías I, Oyagüez I, Alvarez-Sala LA, García-Bragado F, Navarro A, González P, De Andrés-Nogales F, Soto J.

Farm Hosp. 2016 May 1;40(3):187-208. doi: 10.7399/fh.2016.40.3.10461.


Cost-Effectiveness and Cost-Utility Analysis of Ingenol Mebutate Versus Diclofenac 3% and Imiquimod 5% in the Treatment of Actinic Keratosis in Spain.

Elías I, Ortega-Joaquín N, de la Cueva P, Del Pozo LJ, Moreno-Ramírez D, Boada A, Aguilar M, Mirada A, Mosquera E, Gibbons C, Oyagüez I.

Actas Dermosifiliogr. 2016 Jul-Aug;107(6):498-508. doi: 10.1016/ Epub 2016 Apr 26. English, Spanish.


Postural adjustments in young ballet dancers compared to age matched controls.

Iunes DH, Elias IF, Carvalho LC, Dionísio VC.

Phys Ther Sport. 2016 Jan;17:51-7. doi: 10.1016/j.ptsp.2015.04.004. Epub 2015 May 9.


Budget Impact Analysis of Apremilast In Patients With Psoriatic Arthritis In Spain.

Almodóvar R, Gonzalez CM, Caloto T, Elías I, Oyagüez I, Tencer T.

Value Health. 2015 Nov;18(7):A646. doi: 10.1016/j.jval.2015.09.2313. Epub 2015 Oct 20. No abstract available.


Cost-Utility Analysis of Apremilast for The Treatment of Psoriatic Arthritis Patients In Spain.

Gonzalez CM, Almodóvar R, Caloto T, Echave M, Elías I, Tencer T.

Value Health. 2015 Nov;18(7):A645. doi: 10.1016/j.jval.2015.09.2308. Epub 2015 Oct 20. No abstract available.


Cost-Effectiveness Of Tiotropium In The Treatment Of Patients With Asthma.

Echave M, Ojanguren ME, Elías I, de Andrés-Nogales F, Oyagüez I, Casado M, Crespo C.

Value Health. 2015 Nov;18(7):A501-2. doi: 10.1016/j.jval.2015.09.1420. Epub 2015 Oct 20. No abstract available.


Cost-Utility Analysis of Ingenol Mebutate Versus Diclofenac 3% for Actinic Keratosis Treatment In Spain.

Elias I, Ortega-Joaquin N, Aguilar M, Moreno D, Boada A, Del Pozo LJ, de la Cueva P, Mirada A, Mosquera E, Gibbons C, Oyagüez I.

Value Health. 2015 Nov;18(7):A423-4. doi: 10.1016/j.jval.2015.09.573. Epub 2015 Oct 20. No abstract available.


Cost-Utility Analysis of Ingenol Mebutate Versus Imiquimod 5% for Actinic Keratosis Treatment In Spain.

Ortega-Joaquin N, Elías I, de la Cueva P, Del Pozo LJ, Boada A, Moreno D, Aguilar M, Mosquera E, Mirada A, Gibbons C, Oyagüez I.

Value Health. 2015 Nov;18(7):A423. doi: 10.1016/j.jval.2015.09.569. Epub 2015 Oct 20. No abstract available.


Budget Impact Analysis of Apremilast on Moderate to Severe Psoriasis In Spain.

Vanaclocha F, Carrascosa JM, Caloto T, Elías I, Echave M, Tencer T.

Value Health. 2015 Nov;18(7):A421. doi: 10.1016/j.jval.2015.09.559. Epub 2015 Oct 20. No abstract available.


HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance.

Arce-Cerezo A, García M, Rodríguez-Nuevo A, Crosa-Bonell M, Enguix N, Peró A, Muñoz S, Roca C, Ramos D, Franckhauser S, Elias I, Ferre T, Pujol A, Ruberte J, Villena JA, Bosch F, Riu E.

Sci Rep. 2015 Sep 28;5:14487. doi: 10.1038/srep14487.


A randomized, controlled phase III trial of nab-Paclitaxel versus dacarbazine in chemotherapy-naïve patients with metastatic melanoma.

Hersh EM, Del Vecchio M, Brown MP, Kefford R, Loquai C, Testori A, Bhatia S, Gutzmer R, Conry R, Haydon A, Robert C, Ernst S, Homsi J, Grob JJ, Kendra K, Agarwala SS, Li M, Clawson A, Brachmann C, Karnoub M, Elias I, Renschler MF, Hauschild A.

Ann Oncol. 2015 Nov;26(11):2267-74. doi: 10.1093/annonc/mdv324. Epub 2015 Sep 26.


AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease.

Vilà L, Elias I, Roca C, Ribera A, Ferré T, Casellas A, Lage R, Franckhauser S, Bosch F.

Mol Ther Methods Clin Dev. 2014 Oct 1;1:14039. doi: 10.1038/mtm.2014.39. eCollection 2014.


Fastphylo: fast tools for phylogenetics.

Khan MA, Elias I, Sjölund E, Nylander K, Guimera RV, Schobesberger R, Schmitzberger P, Lagergren J, Arvestad L.

BMC Bioinformatics. 2013 Nov 20;14:334. doi: 10.1186/1471-2105-14-334.


Weekly nab-Rapamycin in patients with advanced nonhematologic malignancies: final results of a phase I trial.

Gonzalez-Angulo AM, Meric-Bernstam F, Chawla S, Falchook G, Hong D, Akcakanat A, Chen H, Naing A, Fu S, Wheler J, Moulder S, Helgason T, Li S, Elias I, Desai N, Kurzrock R.

Clin Cancer Res. 2013 Oct 1;19(19):5474-84. doi: 10.1158/1078-0432.CCR-12-3110.


In vivo adeno-associated viral vector-mediated genetic engineering of white and brown adipose tissue in adult mice.

Jimenez V, Muñoz S, Casana E, Mallol C, Elias I, Jambrina C, Ribera A, Ferre T, Franckhauser S, Bosch F.

Diabetes. 2013 Dec;62(12):4012-22. doi: 10.2337/db13-0311. Epub 2013 Sep 16.


New insights into adipose tissue VEGF-A actions in the control of obesity and insulin resistance.

Elias I, Franckhauser S, Bosch F.

Adipocyte. 2013 Apr 1;2(2):109-12. doi: 10.4161/adip.22880.


The detrimental danger of Water-Pipe (Hookah) transcends the hazardous consequences of general health to the driving behavior.

Elias W, Assy N, Elias I, Toledo T, Yassin M, Bowirrat A.

J Transl Med. 2012 Jun 18;10:126. doi: 10.1186/1479-5876-10-126.


Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance.

Elias I, Franckhauser S, Ferré T, Vilà L, Tafuro S, Muñoz S, Roca C, Ramos D, Pujol A, Riu E, Ruberte J, Bosch F.

Diabetes. 2012 Jul;61(7):1801-13. doi: 10.2337/db11-0832. Epub 2012 Apr 20.


Stomatin-like protein 2 binds cardiolipin and regulates mitochondrial biogenesis and function.

Christie DA, Lemke CD, Elias IM, Chau LA, Kirchhof MG, Li B, Ball EH, Dunn SD, Hatch GM, Madrenas J.

Mol Cell Biol. 2011 Sep;31(18):3845-56. doi: 10.1128/MCB.05393-11. Epub 2011 Jul 11.


Chronically increased glucose uptake by adipose tissue leads to lactate production and improved insulin sensitivity rather than obesity in the mouse.

Muñoz S, Franckhauser S, Elias I, Ferré T, Hidalgo A, Monteys AM, Molas M, Cerdán S, Pujol A, Ruberte J, Bosch F.

Diabetologia. 2010 Nov;53(11):2417-30. doi: 10.1007/s00125-010-1840-7. Epub 2010 Jul 10.


Osteochondral lesions of the distal tibial plafond: localization and morphologic characteristics with an anatomical grid.

Elias I, Raikin SM, Schweitzer ME, Besser MP, Morrison WB, Zoga AC.

Foot Ankle Int. 2009 Jun;30(6):524-9. doi: 10.3113/FAI.2009.0524.


Heavy vehicle driver fatalities: learning's from fatal road crash investigations in Victoria.

Brodie L, Lyndal B, Elias IJ.

Accid Anal Prev. 2009 May;41(3):557-64. doi: 10.1016/j.aap.2009.02.005. Epub 2009 Feb 26.


Prediction of midfoot instability in the subtle Lisfranc injury. Comparison of magnetic resonance imaging with intraoperative findings.

Raikin SM, Elias I, Dheer S, Besser MP, Morrison WB, Zoga AC.

J Bone Joint Surg Am. 2009 Apr;91(4):892-9. doi: 10.2106/JBJS.H.01075.


Outcomes of chronic insertional Achilles tendinosis using FHL autograft through single incision.

Elias I, Raikin SM, Besser MP, Nazarian LN.

Foot Ankle Int. 2009 Mar;30(3):197-204. doi: 10.3113/FAI.2009.0197.


The effect of prostaglandin analogs and prostamide on central corneal thickness.

Hatanaka M, Vessani RM, Elias IR, Morita C, Susanna R Jr.

J Ocul Pharmacol Ther. 2009 Feb;25(1):51-3. doi: 10.1089/jop.2007.0125.


MRI of injuries to the first interosseous cuneometatarsal (Lisfranc) ligament.

Macmahon PJ, Dheer S, Raikin SM, Elias I, Morrison WB, Kavanagh EC, Zoga A.

Skeletal Radiol. 2009 Mar;38(3):255-60. doi: 10.1007/s00256-008-0613-6. Epub 2008 Dec 2.


Magnetic resonance imaging findings in bipartite medial cuneiform - a potential pitfall in diagnosis of midfoot injuries: a case series.

Elias I, Dheer S, Zoga AC, Raikin SM, Morrison WB.

J Med Case Rep. 2008 Aug 13;2:272. doi: 10.1186/1752-1947-2-272.


Combination chemotherapy and ALVAC-CEA/B7.1 vaccine in patients with metastatic colorectal cancer.

Kaufman HL, Lenz HJ, Marshall J, Singh D, Garett C, Cripps C, Moore M, von Mehren M, Dalfen R, Heim WJ, Conry RM, Urba WJ, Benson AB 3rd, Yu M, Caterini J, Kim-Schulze S, Debenedette M, Salha D, Vogel T, Elias I, Berinstein NL.

Clin Cancer Res. 2008 Aug 1;14(15):4843-9. doi: 10.1158/1078-0432.CCR-08-0276.


Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease.

Blohmke CJ, Victor RE, Hirschfeld AF, Elias IM, Hancock DG, Lane CR, Davidson AG, Wilcox PG, Smith KD, Overhage J, Hancock RE, Turvey SE.

J Immunol. 2008 Jun 1;180(11):7764-73.


Intrasheath subluxation of the peroneal tendons.

Raikin SM, Elias I, Nazarian LN.

J Bone Joint Surg Am. 2008 May;90(5):992-9. doi: 10.2106/JBJS.G.00801.


Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice.

Franckhauser S, Elias I, Rotter Sopasakis V, Ferré T, Nagaev I, Andersson CX, Agudo J, Ruberte J, Bosch F, Smith U.

Diabetologia. 2008 Jul;51(7):1306-16. doi: 10.1007/s00125-008-0998-8. Epub 2008 Apr 24.


Bone stress injury of the ankle in professional ballet dancers seen on MRI.

Elias I, Zoga AC, Raikin SM, Peterson JR, Besser MP, Morrison WB, Schweitzer ME.

BMC Musculoskelet Disord. 2008 Mar 28;9:39. doi: 10.1186/1471-2474-9-39.


Inferring horizontal transfers in the presence of rearrangements by the minimum evolution criterion.

Birin H, Gal-Or Z, Elias I, Tuller T.

Bioinformatics. 2008 Mar 15;24(6):826-32. doi: 10.1093/bioinformatics/btn024. Epub 2008 Jan 18.


Reconstruction for missed or neglected Achilles tendon rupture with V-Y lengthening and flexor hallucis longus tendon transfer through one incision.

Elias I, Besser M, Nazarian LN, Raikin SM.

Foot Ankle Int. 2007 Dec;28(12):1238-48. doi: 10.3113/FAI.2007.1238.


Incidence and morphologic characteristics of benign calcaneal cystic lesions on MRI.

Elias I, Zoga AC, Raikin SM, Schweitzer ME, Morrison WB.

Foot Ankle Int. 2007 Jun;28(6):707-14.


Recurrent burner syndrome due to presumed cervical spine osteoblastoma in a collision sport athlete - a case report.

Elias I, Pahl MA, Zoga AC, Goins ML, Vaccaro AR.

J Brachial Plex Peripher Nerve Inj. 2007 Jun 6;2:13.


A specific bone marrow edema around the foot and ankle following trauma and immobilization therapy: pattern description and potential clinical relevance.

Elias I, Zoga AC, Schweitzer ME, Ballehr L, Morrison WB, Raikin SM.

Foot Ankle Int. 2007 Apr;28(4):463-71.


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