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Items: 1 to 50 of 255

1.

It Takes "Guts" to Cause Joint Inflammation: Role of Innate-Like T Cells.

Mortier C, Govindarajan S, Venken K, Elewaut D.

Front Immunol. 2018 Jun 29;9:1489. doi: 10.3389/fimmu.2018.01489. eCollection 2018. Review.

2.

Response to: 'The use of dual-energy CT to detect and depict bone marrow oedema in rheumatoid arthritis: is it ready to substitute MRI?' by Wu et al.

Jans L, De Kock I, Herregods N, Verstraete KL, Van den Bosch FE, Carron P, Oei EH, Elewaut D, Jacques P.

Ann Rheum Dis. 2018 Jul 12. pii: annrheumdis-2018-213960. doi: 10.1136/annrheumdis-2018-213960. [Epub ahead of print] No abstract available.

PMID:
30002086
3.

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.

Zhao M, Svensson MND, Venken K, Chawla A, Liang S, Engel I, Mydel P, Day J, Elewaut D, Bottini N, Kronenberg M.

Nat Commun. 2018 Jul 6;9(1):2627. doi: 10.1038/s41467-018-05095-7.

4.

The Role of the Microbiome in Gut and Joint Inflammation in Psoriatic Arthritis and Spondyloarthritis.

Gilis E, Mortier C, Venken K, Debusschere K, Vereecke L, Elewaut D.

J Rheumatol Suppl. 2018 Jun;94:36-39. doi: 10.3899/jrheum.180135.

PMID:
29858352
5.

A natural killer T-cell subset that protects against airway hyperreactivity.

Chuang YT, Leung K, Chang YJ, DeKruyff RH, Savage PB, Cruse R, Benoit C, Elewaut D, Baumgarth N, Umetsu DT.

J Allergy Clin Immunol. 2018 May 29. pii: S0091-6749(18)30769-3. doi: 10.1016/j.jaci.2018.03.022. [Epub ahead of print]

PMID:
29852257
6.

High rate of drug-free remission after induction therapy with golimumab in early peripheral spondyloarthritis.

Carron P, Varkas G, Renson T, Colman R, Elewaut D, Van den Bosch F.

Arthritis Rheumatol. 2018 May 27. doi: 10.1002/art.40573. [Epub ahead of print]

PMID:
29806090
7.

Inflammatory bowel disease and acute anterior uveitis, but not psoriasis are associated with disease duration in Axial SpA: results from the (Be)Giant and ASPECT cohort.

Varkas G, Vastesaeger N, Cypers H, Colman R, Renson T, Van Praet L, Carron P, Raeman F, Devinck M, Gyselbrecht L, Corluy L, Piette Y, Lenaerts J, Thevissen K, Vanneuville B, Van den Bosch F, Elewaut D.

Arthritis Rheumatol. 2018 May 9. doi: 10.1002/art.40551. [Epub ahead of print]

PMID:
29740978
8.

The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis.

Veale DJ, McGonagle D, McInnes IB, Krueger JG, Ritchlin CT, Elewaut D, Kanik KS, Hendrikx T, Berstein G, Hodge J, Telliez JB.

Rheumatology (Oxford). 2018 Apr 3. doi: 10.1093/rheumatology/key070. [Epub ahead of print]

PMID:
29618084
9.

Tumour necrosis factor: out of my heart!

Vereecke L, Elewaut D.

Ann Rheum Dis. 2018 Jun;77(6):793-794. doi: 10.1136/annrheumdis-2018-213118. Epub 2018 Apr 3. No abstract available.

PMID:
29615412
10.

Dual-energy CT: a new imaging modality for bone marrow oedema in rheumatoid arthritis.

Jans L, De Kock I, Herregods N, Verstraete K, Van den Bosch F, Carron P, Oei EH, Elewaut D, Jacques P.

Ann Rheum Dis. 2018 Jun;77(6):958-960. doi: 10.1136/annrheumdis-2018-213152. Epub 2018 Mar 1. No abstract available.

PMID:
29496720
11.

Response to: 'Simultaneous inhibition of α4/β7 integrin and tumor necrosis factor-α in concomitant spondyloarthritis and inflammatory bowel disease' by Richard et al.

Varkas G, Elewaut D.

Ann Rheum Dis. 2018 Jan 26. pii: annrheumdis-2017-212858. doi: 10.1136/annrheumdis-2017-212858. [Epub ahead of print] No abstract available.

PMID:
29374010
12.

Effect of mechanical stress on magnetic resonance imaging of the sacroiliac joints: assessment of military recruits by magnetic resonance imaging study.

Varkas G, de Hooge M, Renson T, De Mits S, Carron P, Jacques P, Moris M, Souverijns G, Jans L, Elewaut D, Van den Bosch F.

Rheumatology (Oxford). 2018 Mar 1;57(3):588. doi: 10.1093/rheumatology/kex534. No abstract available.

PMID:
29329434
13.

Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1.

Bloch Y, Bouchareychas L, Merceron R, Składanowska K, Van den Bossche L, Detry S, Govindarajan S, Elewaut D, Haerynck F, Dullaers M, Adamopoulos IE, Savvides SN.

Immunity. 2018 Jan 16;48(1):45-58.e6. doi: 10.1016/j.immuni.2017.12.008. Epub 2017 Dec 26.

PMID:
29287995
14.

Effect of mechanical stress on magnetic resonance imaging of the sacroiliac joints: assessment of military recruits by magnetic resonance imaging study.

Varkas G, de Hooge M, Renson T, De Mits S, Carron P, Jacques P, Moris M, Souverijns G, Jans L, Elewaut D, Van den Bosch F.

Rheumatology (Oxford). 2018 Mar 1;57(3):508-513. doi: 10.1093/rheumatology/kex491. Erratum in: Rheumatology (Oxford). 2018 Mar 1;57(3):588.

PMID:
29253272
15.

Enthesitis: from pathophysiology to treatment.

Schett G, Lories RJ, D'Agostino MA, Elewaut D, Kirkham B, Soriano ER, McGonagle D.

Nat Rev Rheumatol. 2017 Nov 21;13(12):731-741. doi: 10.1038/nrrheum.2017.188. Review.

PMID:
29158573
16.

Spondyloarthropathies: Ruminococcus on the horizon in arthritic disease.

Vereecke L, Elewaut D.

Nat Rev Rheumatol. 2017 Oct;13(10):574-576. doi: 10.1038/nrrheum.2017.130. Epub 2017 Aug 17. No abstract available.

PMID:
28814815
17.

Galactosylsphingamides: new α-GalCer analogues to probe the F'-pocket of CD1d.

Guillaume J, Wang J, Janssens J, Remesh SG, Risseeuw MDP, Decruy T, Froeyen M, Elewaut D, Zajonc DM, Calenbergh SV.

Sci Rep. 2017 Jun 27;7(1):4276. doi: 10.1038/s41598-017-04461-7.

18.

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues.

Janssens J, Decruy T, Venken K, Seki T, Krols S, Van der Eycken J, Tsuji M, Elewaut D, Van Calenbergh S.

ACS Med Chem Lett. 2017 May 5;8(6):642-647. doi: 10.1021/acsmedchemlett.7b00107. eCollection 2017 Jun 8.

19.

Leptin receptor antagonism of iNKT cell function: a novel strategy to combat multiple myeloma.

Favreau M, Menu E, Gaublomme D, Vanderkerken K, Faict S, Maes K, De Bruyne E, Govindarajan S, Drennan M, Van Calenbergh S, Leleu X, Zabeau L, Tavernier J, Venken K, Elewaut D.

Leukemia. 2017 Dec;31(12):2678-2685. doi: 10.1038/leu.2017.146. Epub 2017 May 11.

PMID:
28490813
20.

ASAS definition for sacroiliitis on MRI in SpA: applicable to children?

Herregods N, Dehoorne J, Van den Bosch F, Jaremko JL, Van Vlaenderen J, Joos R, Baraliakos X, Varkas G, Verstraete K, Elewaut D, Jans L.

Pediatr Rheumatol Online J. 2017 Apr 11;15(1):24. doi: 10.1186/s12969-017-0159-z.

21.

Both mucosal-associated invariant and natural killer T-cell deficiency in multiple myeloma can be countered by PD-1 inhibition.

Favreau M, Venken K, Faict S, Maes K, De Veirman K, De Bruyne E, Leleu X, Boon L, Elewaut D, Vanderkerken K, Menu E.

Haematologica. 2017 Jul;102(7):e266-e270. doi: 10.3324/haematol.2017.163758. Epub 2017 Apr 6. No abstract available.

22.

CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis.

Bogie JF, Boelen E, Louagie E, Delputte P, Elewaut D, van Horssen J, Hendriks JJ, Hellings N.

Mult Scler. 2018 Mar;24(3):290-300. doi: 10.1177/1352458517698759. Epub 2017 Mar 9.

PMID:
28277099
23.

Synthesis of C6''-modified α-C-GalCer analogues as mouse and human iNKT cell agonists.

Guillaume J, Seki T, Decruy T, Venken K, Elewaut D, Tsuji M, Van Calenbergh S.

Org Biomol Chem. 2017 Mar 8;15(10):2217-2225. doi: 10.1039/c7ob00081b.

PMID:
28221388
24.

Anti-TNF-induced remission in very early peripheral spondyloarthritis: the CRESPA study.

Carron P, Varkas G, Cypers H, Van Praet L, Elewaut D, Van den Bosch F; CRESPA investigator group.

Ann Rheum Dis. 2017 Aug;76(8):1389-1395. doi: 10.1136/annrheumdis-2016-210775. Epub 2017 Feb 17.

PMID:
28213565
25.

Response to: 'Clinical benefit of vedolizumab on articular manifestations in patients with active spondyloarthritis associated with inflammatory bowel disease' by Orlando et al.

Varkas G, Van den Bosch F, Elewaut D.

Ann Rheum Dis. 2017 Sep;76(9):e32. doi: 10.1136/annrheumdis-2016-211045. Epub 2017 Feb 9. No abstract available.

PMID:
28183720
26.

Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure.

Verhamme FM, Seys LJM, De Smet EG, Provoost S, Janssens W, Elewaut D, Joos GF, Brusselle GG, Bracke KR.

Mucosal Immunol. 2017 Nov;10(6):1400-1411. doi: 10.1038/mi.2017.3. Epub 2017 Feb 1.

PMID:
28145442
27.

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis.

Ciccia F, Guggino G, Rizzo A, Alessandro R, Luchetti MM, Milling S, Saieva L, Cypers H, Stampone T, Di Benedetto P, Gabrielli A, Fasano A, Elewaut D, Triolo G.

Ann Rheum Dis. 2017 Jun;76(6):1123-1132. doi: 10.1136/annrheumdis-2016-210000. Epub 2017 Jan 9.

PMID:
28069576
28.

Monoclonal antibody binding to the macrophage-specific receptor sialoadhesin alters the phagocytic properties of human and mouse macrophages.

De Schryver M, Cappoen D, Elewaut D, Nauwynck HJ, Maes L, Caljon G, Cos P, Delputte PL.

Cell Immunol. 2017 Feb;312:51-60. doi: 10.1016/j.cellimm.2016.11.009. Epub 2016 Dec 9.

PMID:
27993350
29.

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.

Van Welden S, De Vos M, Wielockx B, Tavernier SJ, Dullaers M, Neyt S, Descamps B, Devisscher L, Devriese S, Van den Bossche L, Holvoet T, Baeyens A, Correale C, D'Alessio S, Vanhove C, De Vos F, Verhasselt B, Breier G, Lambrecht BN, Janssens S, Carmeliet P, Danese S, Elewaut D, Laukens D, Hindryckx P.

J Pathol. 2017 Mar;241(4):547-558. doi: 10.1002/path.4861. Epub 2017 Jan 27.

PMID:
27981571
30.

99mTc-labelled S-HYNIC certolizumab pegol in rheumatoid arthritis and spondyloarthritis patients: a biodistribution and dosimetry study.

Lambert B, Carron P, D'Asseler Y, Bacher K, Van den Bosch F, Elewaut D, Verbruggen G, Beyaert R, Dumolyn C, De Vos F.

EJNMMI Res. 2016 Dec;6(1):88. Epub 2016 Dec 12.

31.

Immunoscintigraphic detection of tumour necrosis factor by radiolabelled certolizumab pegol in patients with erosive hand osteoarthritis: a proof-of-concept study.

Wittoek R, Carron P, Lambert B, Meersseman P, Verbruggen G, Van den Bosch F, Elewaut D.

Ann Rheum Dis. 2018 Feb;77(2):310-311. doi: 10.1136/annrheumdis-2016-210354. Epub 2016 Dec 8. No abstract available.

PMID:
27932347
32.

An induction or flare of arthritis and/or sacroiliitis by vedolizumab in inflammatory bowel disease: a case series.

Varkas G, Thevissen K, De Brabanter G, Van Praet L, Czul-Gurdian F, Cypers H, De Kock J, Carron P, De Vos M, Hindryckx P, Arts J, Vanneuville I, Schoenaers P, Claerhout B, Abreu M, Van den Bosch F, Elewaut D.

Ann Rheum Dis. 2017 May;76(5):878-881. doi: 10.1136/annrheumdis-2016-210233. Epub 2016 Nov 29.

PMID:
27899374
33.

A Nationwide Survey on Patient's versus Physician´s Evaluation of Biological Therapy in Rheumatoid Arthritis in Relation to Disease Activity and Route of Administration: The Be-Raise Study.

De Mits S, Lenaerts J, Vander Cruyssen B, Mielants H, Westhovens R, Durez P, Elewaut D; Be-Raise study group.

PLoS One. 2016 Nov 28;11(11):e0166607. doi: 10.1371/journal.pone.0166607. eCollection 2016.

34.

What rheumatologists need to know about innate lymphocytes.

Exley MA, Tsokos GC, Mills KH, Elewaut D, Mulhearn B.

Nat Rev Rheumatol. 2016 Nov;12(11):658-668. doi: 10.1038/nrrheum.2016.140. Epub 2016 Sep 2. Review.

PMID:
27586381
35.

The role of Ly49E receptor expression on murine intraepithelial lymphocytes in intestinal cancer development and progression.

Van Acker A, Louagie E, Filtjens J, Taveirne S, Van Ammel E, Kerre T, Elewaut D, Taghon T, Vandekerckhove B, Plum J, Leclercq G.

Cancer Immunol Immunother. 2016 Nov;65(11):1365-1375. Epub 2016 Sep 1.

PMID:
27585789
36.

Assessment of sensitivity to change of the European Scleroderma Study Group activity index.

Melsens K, De Keyser F, Decuman S, Brusselle G, De Pauw M, Deschepper E, De Wilde K, Elewaut D, Piette Y, Vandecasteele E, Smith V.

Clin Exp Rheumatol. 2016 Sep-Oct;34 Suppl 100(5):148-151. Epub 2016 Jul 18.

PMID:
27463733
37.

MR signal in the sacroiliac joint space in spondyloarthritis: a new sign.

Laloo F, Herregods N, Varkas G, Jaremko JL, Baraliakos X, Elewaut D, Van den Bosch F, Verstraete K, Jans L.

Eur Radiol. 2017 May;27(5):2024-2030. doi: 10.1007/s00330-016-4587-9. Epub 2016 Sep 20.

PMID:
27651143
38.

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.

Drennan MB, Govindarajan S, Verheugen E, Coquet JM, Staal J, McGuire C, Taghon T, Leclercq G, Beyaert R, van Loo G, Lambrecht BN, Elewaut D.

J Exp Med. 2016 Sep 19;213(10):1973-81. doi: 10.1084/jem.20151065. Epub 2016 Aug 22.

39.

A20 inhibition of STAT1 expression in myeloid cells: a novel endogenous regulatory mechanism preventing development of enthesitis.

De Wilde K, Martens A, Lambrecht S, Jacques P, Drennan MB, Debusschere K, Govindarajan S, Coudenys J, Verheugen E, Windels F, Catrysse L, Lories R, McGonagle D, Beyaert R, van Loo G, Elewaut D.

Ann Rheum Dis. 2017 Mar;76(3):585-592. doi: 10.1136/annrheumdis-2016-209454. Epub 2016 Aug 22.

PMID:
27551052
40.

MAIT cells: not just another brick in the wall.

Debusschere K, Lories RJ, Elewaut D.

Ann Rheum Dis. 2016 Dec;75(12):2057-2059. doi: 10.1136/annrheumdis-2016-209695. Epub 2016 Jul 29. No abstract available.

PMID:
27474762
41.

Scintigraphic detection of TNF-driven inflammation by radiolabelled certolizumab pegol in patients with rheumatoid arthritis and spondyloarthritis.

Carron P, Lambert B, Van Praet L, De Vos F, Varkas G, Jans L, Elewaut D, Van den Bosch F.

RMD Open. 2016 Jun 24;2(1):e000265. doi: 10.1136/rmdopen-2016-000265. eCollection 2016.

42.

Brief Report: Dialister as a Microbial Marker of Disease Activity in Spondyloarthritis.

Tito RY, Cypers H, Joossens M, Varkas G, Van Praet L, Glorieus E, Van den Bosch F, De Vos M, Raes J, Elewaut D.

Arthritis Rheumatol. 2017 Jan;69(1):114-121. doi: 10.1002/art.39802. Epub 2016 Dec 1.

43.

How the microbiota shapes rheumatic diseases.

Van de Wiele T, Van Praet JT, Marzorati M, Drennan MB, Elewaut D.

Nat Rev Rheumatol. 2016 Jul;12(7):398-411. doi: 10.1038/nrrheum.2016.85. Epub 2016 Jun 16. Review.

PMID:
27305853
44.

The quest for autoreactive antibodies in nasal polyps.

De Schryver E, Calus L, Bonte H, Natalie R, Gould H, Donovan E, Elewaut D, Valenta R, Mittermann I, Gutermuth J, Seher T, Schleimer RP, Tan BK, Derycke L, Van Zele T, Bachert C, Gevaert P.

J Allergy Clin Immunol. 2016 Sep;138(3):893-895.e5. doi: 10.1016/j.jaci.2016.03.040. Epub 2016 May 6. No abstract available.

45.

New immune cells in spondyloarthritis: Key players or innocent bystanders?

Venken K, Elewaut D.

Best Pract Res Clin Rheumatol. 2015 Dec;29(6):706-14. doi: 10.1016/j.berh.2016.02.002. Epub 2016 Mar 12. Review.

PMID:
27107508
46.

Does an NKT-cell-based immunotherapeutic approach have a future in multiple myeloma?

Favreau M, Vanderkerken K, Elewaut D, Venken K, Menu E.

Oncotarget. 2016 Apr 26;7(17):23128-40. doi: 10.18632/oncotarget.7440. Review.

47.

Elevated calprotectin levels reveal bowel inflammation in spondyloarthritis.

Cypers H, Varkas G, Beeckman S, Debusschere K, Vogl T, Roth J, Drennan MB, Lavric M, Foell D, Cuvelier CA, De Vos M, Delanghe J, Van den Bosch F, Elewaut D.

Ann Rheum Dis. 2016 Jul;75(7):1357-62. doi: 10.1136/annrheumdis-2015-208025. Epub 2015 Dec 23.

48.

An Optimized Method for Isolating and Expanding Invariant Natural Killer T Cells from Mouse Spleen.

Govindarajan S, Elewaut D, Drennan M.

J Vis Exp. 2015 Oct 29;(105):e53256. doi: 10.3791/53256.

49.

Diagnositic value of pelvic enthesitis on MRI of the sacroiliac joints in enthesitis related arthritis.

Herregods N, Dehoorne J, Pattyn E, Jaremko JL, Baraliakos X, Elewaut D, Van Vlaenderen J, Van den Bosch F, Joos R, Verstraete K, Jans L.

Pediatr Rheumatol Online J. 2015 Nov 10;13(1):46. doi: 10.1186/s12969-015-0045-5.

50.

The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFΔARE Mice.

Allais L, Kumar S, Debusschere K, Verschuere S, Maes T, De Smet R, Conickx G, De Vos M, Laukens D, Joos GF, Brusselle GG, Elewaut D, Cuvelier CA, Bracke KR.

PLoS One. 2015 Nov 2;10(11):e0141570. doi: 10.1371/journal.pone.0141570. eCollection 2015.

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