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Items: 1 to 50 of 276

1.

B cell tetherin: a flow-cytometric cell-specific assay for response to Type-I interferon predicts clinical features and flares in SLE.

El-Sherbiny YM, Md Yusof Y, Psarras A, Hensor EMA, Kabba KZ, Dutton K, Mohamed AAA, Elewaut D, McGonagle D, Tooze R, Doody G, Wittmann M, Emery P, Vital EM.

Arthritis Rheumatol. 2019 Dec 5. doi: 10.1002/art.41187. [Epub ahead of print]

PMID:
31804007
2.

WITHDRAWN: This article has been withdrawn.

De Spiegeleer A, Elewaut D, Van Den Noortgate N, Janssens Y, Debunne N, Van Langenhove S, Govindarajan S, De Spiegeleer B, Wynendaele E.

Biochim Biophys Acta Mol Basis Dis. 2019 Oct 31:165585. doi: 10.1016/j.bbadis.2019.165585. [Epub ahead of print]

PMID:
31678164
3.

Expert consensus: practical algorithms for management of inflammatory bowel disease patients presenting with back pain or peripheral arthropathies.

Varkas G, Ribbens C, Louis E, Van den Bosch F, Lories R, Vermeire S, Elewaut D, De Vos M.

Aliment Pharmacol Ther. 2019 Dec;50(11-12):1204-1213. doi: 10.1111/apt.15519. Epub 2019 Oct 25.

PMID:
31650573
4.

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.

Bonnardel J, T'Jonck W, Gaublomme D, Browaeys R, Scott CL, Martens L, Vanneste B, De Prijck S, Nedospasov SA, Kremer A, Van Hamme E, Borghgraef P, Toussaint W, De Bleser P, Mannaerts I, Beschin A, van Grunsven LA, Lambrecht BN, Taghon T, Lippens S, Elewaut D, Saeys Y, Guilliams M.

Immunity. 2019 Oct 15;51(4):638-654.e9. doi: 10.1016/j.immuni.2019.08.017. Epub 2019 Sep 24.

5.

MRI of the axial skeleton in spondyloarthritis: the many faces of new bone formation.

Laloo F, Herregods N, Jaremko JL, Carron P, Elewaut D, Van den Bosch F, Verstraete K, Jans L.

Insights Imaging. 2019 Jul 24;10(1):67. doi: 10.1186/s13244-019-0752-4. Review.

6.

Low specificity but high sensitivity of inflammatory back pain criteria in rheumatology settings in Europe: confirmation of findings from a German cohort study.

de Hooge M, van Gaalen FA, Renson T, De Craemer AS, van de Sande MG, Ramonda R, Fagerli KM, Jacobsson LTH, van der Heijde D, Elewaut D, Van den Bosch F.

Ann Rheum Dis. 2019 Nov;78(11):1605-1606. doi: 10.1136/annrheumdis-2019-215742. Epub 2019 Jul 13. No abstract available.

PMID:
31302595
7.

Deletion of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis.

Gilis E, Gaublomme D, Staal J, Venken K, Dhaenens M, Lambrecht S, Coudenys J, Decruy T, Schryvers N, Driege Y, Dumas E, Demeyer A, De Muynck A, van Hengel J, Van Hoorebeke L, Deforce D, Beyaert R, Elewaut D.

Arthritis Rheumatol. 2019 Dec;71(12):2005-2015. doi: 10.1002/art.41029. Epub 2019 Nov 9.

PMID:
31259485
8.

Changing the wolf from outside: how microbiota trigger systemic lupus erythematosus.

Peene I, Elewaut D.

Ann Rheum Dis. 2019 Jul;78(7):867-869. doi: 10.1136/annrheumdis-2019-215221. Epub 2019 May 10. No abstract available.

PMID:
31076388
9.

Risks and benefits of corticosteroids in arthritic diseases in the clinic.

Petta I, Peene I, Elewaut D, Vereecke L, De Bosscher K.

Biochem Pharmacol. 2019 Jul;165:112-125. doi: 10.1016/j.bcp.2019.04.009. Epub 2019 Apr 10. Review.

PMID:
30978323
10.

Running promotes chronicity of arthritis by local modulation of complement activators and impairing T regulatory feedback loops.

Cambré I, Gaublomme D, Schryvers N, Lambrecht S, Lories R, Venken K, Elewaut D.

Ann Rheum Dis. 2019 Jun;78(6):787-795. doi: 10.1136/annrheumdis-2018-214627. Epub 2019 Mar 30.

PMID:
30928902
11.

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients.

Venken K, Jacques P, Mortier C, Labadia ME, Decruy T, Coudenys J, Hoyt K, Wayne AL, Hughes R, Turner M, Van Gassen S, Martens L, Smith D, Harcken C, Wahle J, Wang CT, Verheugen E, Schryvers N, Varkas G, Cypers H, Wittoek R, Piette Y, Gyselbrecht L, Van Calenbergh S, Van den Bosch F, Saeys Y, Nabozny G, Elewaut D.

Nat Commun. 2019 Jan 2;10(1):9. doi: 10.1038/s41467-018-07911-6.

12.

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha.

Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, Tavernier S, Iwawaki T, Bloch Y, Savvides SN, Lambrecht BN, Janssens S, Elewaut D, Drennan MB.

Nat Commun. 2018 Dec 17;9(1):5340. doi: 10.1038/s41467-018-07758-x.

13.

4"-O-Alkylated α-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.

Janssens J, Bitra A, Wang J, Decruy T, Venken K, van der Eycken J, Elewaut D, Zajonc DM, van Calenbergh S.

ChemMedChem. 2019 Jan 8;14(1):147-168. doi: 10.1002/cmdc.201800649. Epub 2018 Dec 17.

PMID:
30556652
14.

New bone formation in the intervertebral joint space in spondyloarthritis: An MRI study.

Laloo F, Herregods N, Jaremko JL, Carron P, Elewaut D, Van den Bosch F, Verstraete K, Jans L.

Eur J Radiol. 2018 Dec;109:210-217. doi: 10.1016/j.ejrad.2018.11.007. Epub 2018 Nov 6.

PMID:
30527307
15.

Born to run: The paradox of biomechanical force in spondyloarthritis from an evolutionary perspective.

Debusschere K, Cambré I, Gracey E, Elewaut D.

Best Pract Res Clin Rheumatol. 2017 Dec;31(6):887-894. doi: 10.1016/j.berh.2018.07.011. Epub 2018 Sep 1. Review.

PMID:
30509447
16.

The ties that bind: skin, gut and spondyloarthritis.

Gracey E, Dumas E, Yerushalmi M, Qaiyum Z, Inman RD, Elewaut D.

Curr Opin Rheumatol. 2019 Jan;31(1):62-69. doi: 10.1097/BOR.0000000000000569.

PMID:
30407224
17.

Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis.

Cambré I, Gaublomme D, Burssens A, Jacques P, Schryvers N, De Muynck A, Meuris L, Lambrecht S, Carter S, de Bleser P, Saeys Y, Van Hoorebeke L, Kollias G, Mack M, Simoens P, Lories R, Callewaert N, Schett G, Elewaut D.

Nat Commun. 2018 Nov 5;9(1):4613. doi: 10.1038/s41467-018-06933-4.

18.

Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial.

Kloppenburg M, Ramonda R, Bobacz K, Kwok WY, Elewaut D, Huizinga TWJ, Kroon FPB, Punzi L, Smolen JS, Vander Cruyssen B, Wolterbeek R, Verbruggen G, Wittoek R.

Ann Rheum Dis. 2018 Dec;77(12):1757-1764. doi: 10.1136/annrheumdis-2018-213202. Epub 2018 Oct 3.

PMID:
30282670
19.

A novel LPS-responsive beige-like anchor protein (LRBA) mutation presents with normal cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and overactive TH17 immunity.

De Bruyne M, Bogaert DJ, Venken K, Van den Bossche L, Bonroy C, Roels L, Tavernier SJ, van de Vijver E, Driessen A, van Gijn M, Gámez-Diaz L, Elewaut D, Grimbacher B, Haerynck F, Moes N, Dullaers M.

J Allergy Clin Immunol. 2018 Dec;142(6):1968-1971. doi: 10.1016/j.jaci.2018.08.026. Epub 2018 Sep 5. No abstract available.

PMID:
30193839
20.

Checkpoint inhibition in the treatment of multiple myeloma: A way to boost innate-like T cell anti-tumor function?

Venken K, Favreau M, Gaublomme D, Menu E, Vanderkerken K, Elewaut D.

Mol Immunol. 2018 Sep;101:521-526. doi: 10.1016/j.molimm.2018.08.019. Epub 2018 Aug 25. Review.

PMID:
30153633
21.

Dysregulation of NF-kB in glandular epithelial cells results in Sjögren's-like features.

Wang X, Shaalan A, Liefers S, Coudenys J, Elewaut D, Proctor GB, Bootsma H, Kroese FGM, Pringle S.

PLoS One. 2018 Aug 1;13(8):e0200212. doi: 10.1371/journal.pone.0200212. eCollection 2018.

22.

It Takes "Guts" to Cause Joint Inflammation: Role of Innate-Like T Cells.

Mortier C, Govindarajan S, Venken K, Elewaut D.

Front Immunol. 2018 Jun 29;9:1489. doi: 10.3389/fimmu.2018.01489. eCollection 2018. Review.

23.

Response to: 'Use of dual-energy CT to detect and depict bone marrow oedema in rheumatoid arthritis: is it ready to substitute MRI?' by Wu et al.

Jans L, De Kock I, Herregods N, Verstraete KL, Van den Bosch FE, Carron P, Oei EH, Elewaut D, Jacques P.

Ann Rheum Dis. 2019 Sep;78(9):e90. doi: 10.1136/annrheumdis-2018-213960. Epub 2018 Jul 12. No abstract available.

PMID:
30002086
24.

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.

Zhao M, Svensson MND, Venken K, Chawla A, Liang S, Engel I, Mydel P, Day J, Elewaut D, Bottini N, Kronenberg M.

Nat Commun. 2018 Jul 6;9(1):2627. doi: 10.1038/s41467-018-05095-7.

25.

The Role of the Microbiome in Gut and Joint Inflammation in Psoriatic Arthritis and Spondyloarthritis.

Gilis E, Mortier C, Venken K, Debusschere K, Vereecke L, Elewaut D.

J Rheumatol Suppl. 2018 Jun;94:36-39. doi: 10.3899/jrheum.180135.

PMID:
29858352
26.

A natural killer T-cell subset that protects against airway hyperreactivity.

Chuang YT, Leung K, Chang YJ, DeKruyff RH, Savage PB, Cruse R, Benoit C, Elewaut D, Baumgarth N, Umetsu DT.

J Allergy Clin Immunol. 2019 Feb;143(2):565-576.e7. doi: 10.1016/j.jaci.2018.03.022. Epub 2018 May 29.

PMID:
29852257
27.

High Rate of Drug-Free Remission After Induction Therapy With Golimumab in Early Peripheral Spondyloarthritis.

Carron P, Varkas G, Renson T, Colman R, Elewaut D, Van den Bosch F.

Arthritis Rheumatol. 2018 Nov;70(11):1769-1777. doi: 10.1002/art.40573.

28.

Association of Inflammatory Bowel Disease and Acute Anterior Uveitis, but Not Psoriasis, With Disease Duration in Patients With Axial Spondyloarthritis: Results From Two Belgian Nationwide Axial Spondyloarthritis Cohorts.

Varkas G, Vastesaeger N, Cypers H, Colman R, Renson T, Praet LV, Carron P, Raeman F, Devinck M, Gyselbrecht L, Corluy L, Piette Y, Lenaerts J, Thevissen K, Vanneuville B, Bosch FVD, Elewaut D.

Arthritis Rheumatol. 2018 Oct;70(10):1588-1596. doi: 10.1002/art.40551.

29.

The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis.

Veale DJ, McGonagle D, McInnes IB, Krueger JG, Ritchlin CT, Elewaut D, Kanik KS, Hendrikx T, Berstein G, Hodge J, Telliez JB.

Rheumatology (Oxford). 2019 Feb 1;58(2):197-205. doi: 10.1093/rheumatology/key070. Review.

30.

Tumour necrosis factor: out of my heart!

Vereecke L, Elewaut D.

Ann Rheum Dis. 2018 Jun;77(6):793-794. doi: 10.1136/annrheumdis-2018-213118. Epub 2018 Apr 3. No abstract available.

PMID:
29615412
31.

Dual-energy CT: a new imaging modality for bone marrow oedema in rheumatoid arthritis.

Jans L, De Kock I, Herregods N, Verstraete K, Van den Bosch F, Carron P, Oei EH, Elewaut D, Jacques P.

Ann Rheum Dis. 2018 Jun;77(6):958-960. doi: 10.1136/annrheumdis-2018-213152. Epub 2018 Mar 1. No abstract available.

PMID:
29496720
32.

Response to: 'Simultaneous inhibition of α4/β7 integrin and tumor necrosis factor-α in concomitant spondyloarthritis and inflammatory bowel disease' by Richard et al.

Varkas G, Elewaut D.

Ann Rheum Dis. 2018 Dec;77(12):e87. doi: 10.1136/annrheumdis-2017-212858. Epub 2018 Jan 26. No abstract available.

PMID:
29374010
33.

Effect of mechanical stress on magnetic resonance imaging of the sacroiliac joints: assessment of military recruits by magnetic resonance imaging study.

Varkas G, de Hooge M, Renson T, De Mits S, Carron P, Jacques P, Moris M, Souverijns G, Jans L, Elewaut D, Van den Bosch F.

Rheumatology (Oxford). 2018 Mar 1;57(3):588. doi: 10.1093/rheumatology/kex534. No abstract available.

PMID:
29329434
34.

Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1.

Bloch Y, Bouchareychas L, Merceron R, Składanowska K, Van den Bossche L, Detry S, Govindarajan S, Elewaut D, Haerynck F, Dullaers M, Adamopoulos IE, Savvides SN.

Immunity. 2018 Jan 16;48(1):45-58.e6. doi: 10.1016/j.immuni.2017.12.008. Epub 2017 Dec 26.

35.

Effect of mechanical stress on magnetic resonance imaging of the sacroiliac joints: assessment of military recruits by magnetic resonance imaging study.

Varkas G, de Hooge M, Renson T, De Mits S, Carron P, Jacques P, Moris M, Souverijns G, Jans L, Elewaut D, Van den Bosch F.

Rheumatology (Oxford). 2018 Mar 1;57(3):508-513. doi: 10.1093/rheumatology/kex491. Erratum in: Rheumatology (Oxford). 2018 Mar 1;57(3):588.

PMID:
29253272
36.

Enthesitis: from pathophysiology to treatment.

Schett G, Lories RJ, D'Agostino MA, Elewaut D, Kirkham B, Soriano ER, McGonagle D.

Nat Rev Rheumatol. 2017 Nov 21;13(12):731-741. doi: 10.1038/nrrheum.2017.188. Review.

PMID:
29158573
37.

Spondyloarthropathies: Ruminococcus on the horizon in arthritic disease.

Vereecke L, Elewaut D.

Nat Rev Rheumatol. 2017 Oct;13(10):574-576. doi: 10.1038/nrrheum.2017.130. Epub 2017 Aug 17. No abstract available.

PMID:
28814815
38.

Galactosylsphingamides: new α-GalCer analogues to probe the F'-pocket of CD1d.

Guillaume J, Wang J, Janssens J, Remesh SG, Risseeuw MDP, Decruy T, Froeyen M, Elewaut D, Zajonc DM, Calenbergh SV.

Sci Rep. 2017 Jun 27;7(1):4276. doi: 10.1038/s41598-017-04461-7.

39.

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues.

Janssens J, Decruy T, Venken K, Seki T, Krols S, Van der Eycken J, Tsuji M, Elewaut D, Van Calenbergh S.

ACS Med Chem Lett. 2017 May 5;8(6):642-647. doi: 10.1021/acsmedchemlett.7b00107. eCollection 2017 Jun 8.

40.

Leptin receptor antagonism of iNKT cell function: a novel strategy to combat multiple myeloma.

Favreau M, Menu E, Gaublomme D, Vanderkerken K, Faict S, Maes K, De Bruyne E, Govindarajan S, Drennan M, Van Calenbergh S, Leleu X, Zabeau L, Tavernier J, Venken K, Elewaut D.

Leukemia. 2017 Dec;31(12):2678-2685. doi: 10.1038/leu.2017.146. Epub 2017 May 11.

PMID:
28490813
41.

ASAS definition for sacroiliitis on MRI in SpA: applicable to children?

Herregods N, Dehoorne J, Van den Bosch F, Jaremko JL, Van Vlaenderen J, Joos R, Baraliakos X, Varkas G, Verstraete K, Elewaut D, Jans L.

Pediatr Rheumatol Online J. 2017 Apr 11;15(1):24. doi: 10.1186/s12969-017-0159-z.

42.

Both mucosal-associated invariant and natural killer T-cell deficiency in multiple myeloma can be countered by PD-1 inhibition.

Favreau M, Venken K, Faict S, Maes K, De Veirman K, De Bruyne E, Leleu X, Boon L, Elewaut D, Vanderkerken K, Menu E.

Haematologica. 2017 Jul;102(7):e266-e270. doi: 10.3324/haematol.2017.163758. Epub 2017 Apr 6. No abstract available.

43.

CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis.

Bogie JF, Boelen E, Louagie E, Delputte P, Elewaut D, van Horssen J, Hendriks JJ, Hellings N.

Mult Scler. 2018 Mar;24(3):290-300. doi: 10.1177/1352458517698759. Epub 2017 Mar 9.

PMID:
28277099
44.

Synthesis of C6''-modified α-C-GalCer analogues as mouse and human iNKT cell agonists.

Guillaume J, Seki T, Decruy T, Venken K, Elewaut D, Tsuji M, Van Calenbergh S.

Org Biomol Chem. 2017 Mar 8;15(10):2217-2225. doi: 10.1039/c7ob00081b.

PMID:
28221388
45.

Anti-TNF-induced remission in very early peripheral spondyloarthritis: the CRESPA study.

Carron P, Varkas G, Cypers H, Van Praet L, Elewaut D, Van den Bosch F; CRESPA investigator group.

Ann Rheum Dis. 2017 Aug;76(8):1389-1395. doi: 10.1136/annrheumdis-2016-210775. Epub 2017 Feb 17.

PMID:
28213565
46.

Response to: 'Clinical benefit of vedolizumab on articular manifestations in patients with active spondyloarthritis associated with inflammatory bowel disease' by Orlando et al.

Varkas G, Van den Bosch F, Elewaut D.

Ann Rheum Dis. 2017 Sep;76(9):e32. doi: 10.1136/annrheumdis-2016-211045. Epub 2017 Feb 9. No abstract available.

PMID:
28183720
47.

Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure.

Verhamme FM, Seys LJM, De Smet EG, Provoost S, Janssens W, Elewaut D, Joos GF, Brusselle GG, Bracke KR.

Mucosal Immunol. 2017 Nov;10(6):1400-1411. doi: 10.1038/mi.2017.3. Epub 2017 Feb 1.

PMID:
28145442
48.

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis.

Ciccia F, Guggino G, Rizzo A, Alessandro R, Luchetti MM, Milling S, Saieva L, Cypers H, Stampone T, Di Benedetto P, Gabrielli A, Fasano A, Elewaut D, Triolo G.

Ann Rheum Dis. 2017 Jun;76(6):1123-1132. doi: 10.1136/annrheumdis-2016-210000. Epub 2017 Jan 9.

49.

Monoclonal antibody binding to the macrophage-specific receptor sialoadhesin alters the phagocytic properties of human and mouse macrophages.

De Schryver M, Cappoen D, Elewaut D, Nauwynck HJ, Maes L, Caljon G, Cos P, Delputte PL.

Cell Immunol. 2017 Feb;312:51-60. doi: 10.1016/j.cellimm.2016.11.009. Epub 2016 Dec 9.

PMID:
27993350
50.

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.

Van Welden S, De Vos M, Wielockx B, Tavernier SJ, Dullaers M, Neyt S, Descamps B, Devisscher L, Devriese S, Van den Bossche L, Holvoet T, Baeyens A, Correale C, D'Alessio S, Vanhove C, De Vos F, Verhasselt B, Breier G, Lambrecht BN, Janssens S, Carmeliet P, Danese S, Elewaut D, Laukens D, Hindryckx P.

J Pathol. 2017 Mar;241(4):547-558. doi: 10.1002/path.4861. Epub 2017 Jan 27.

PMID:
27981571

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