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Items: 44

1.

Demonstrating laboratory proficiency in bacterial mutagenicity assays for regulatory submission.

Levy DD, Hakura A, Elespuru RK, Escobar PA, Kato M, Lott J, Moore MM, Sugiyama KI.

Mutat Res. 2019 Dec;848:403075. doi: 10.1016/j.mrgentox.2019.07.005. Epub 2019 Jul 12.

2.

Are all bacterial strains required by OECD mutagenicity test guideline TG471 needed?

Williams RV, DeMarini DM, Stankowski LF Jr, Escobar PA, Zeiger E, Howe J, Elespuru R, Cross KP.

Mutat Res. 2019 Dec;848:503081. doi: 10.1016/j.mrgentox.2019.503081. Epub 2019 Aug 9.

3.

Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk.

Harris KL, Myers MB, McKim KL, Elespuru RK, Parsons BL.

Environ Mol Mutagen. 2019 Aug 30. doi: 10.1002/em.22326. [Epub ahead of print] Review.

PMID:
31469467
4.

Genotoxicity Assessment of Nanomaterials: Recommendations on Best Practices, Assays, and Methods.

Elespuru R, Pfuhler S, Aardema MJ, Chen T, Doak SH, Doherty A, Farabaugh CS, Kenny J, Manjanatha M, Mahadevan B, Moore MM, Ou├ędraogo G, Stankowski LF Jr, Tanir JY.

Toxicol Sci. 2018 Aug 1;164(2):391-416. doi: 10.1093/toxsci/kfy100. Review.

PMID:
29701824
5.

Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations.

Dearfield KL, Gollapudi BB, Bemis JC, Benz RD, Douglas GR, Elespuru RK, Johnson GE, Kirkland DJ, LeBaron MJ, Li AP, Marchetti F, Pottenger LH, Rorije E, Tanir JY, Thybaud V, van Benthem J, Yauk CL, Zeiger E, Luijten M.

Environ Mol Mutagen. 2017 Jun;58(5):264-283. doi: 10.1002/em.22045. Epub 2016 Sep 21. Review.

PMID:
27650663
6.

Performance characteristics of the AmpliSeq Cancer Hotspot panel v2 in combination with the Ion Torrent Next Generation Sequencing Personal Genome Machine.

Butler KS, Young MY, Li Z, Elespuru RK, Wood SC.

Regul Toxicol Pharmacol. 2016 Feb;74:178-86. doi: 10.1016/j.yrtph.2015.09.011. Epub 2015 Sep 24.

PMID:
26387931
7.

Silver nanoparticles: correlating nanoparticle size and cellular uptake with genotoxicity.

Butler KS, Peeler DJ, Casey BJ, Dair BJ, Elespuru RK.

Mutagenesis. 2015 Jul;30(4):577-91. doi: 10.1093/mutage/gev020. Epub 2015 May 11.

8.

Assessment of titanium dioxide nanoparticle effects in bacteria: association, uptake, mutagenicity, co-mutagenicity and DNA repair inhibition.

Butler KS, Casey BJ, Garborcauskas GV, Dair BJ, Elespuru RK.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Jul 1;768:14-22. doi: 10.1016/j.mrgentox.2014.04.008. Epub 2014 Apr 24.

PMID:
24769488
9.

Genotoxicity of nanomaterials: refining strategies and tests for hazard identification.

Pfuhler S, Elespuru R, Aardema MJ, Doak SH, Maria Donner E, Honma M, Kirsch-Volders M, Landsiedel R, Manjanatha M, Singer T, Kim JH.

Environ Mol Mutagen. 2013 May;54(4):229-39. doi: 10.1002/em.21770. Epub 2013 Mar 21.

PMID:
23519787
10.

Harnessing genomics to identify environmental determinants of heritable disease.

Yauk CL, Lucas Argueso J, Auerbach SS, Awadalla P, Davis SR, Demarini DM, Douglas GR, Dubrova YE, Elespuru RK, Glover TW, Hales BF, Hurles ME, Klein CB, Lupski JR, Manchester DK, Marchetti F, Montpetit A, Mulvihill JJ, Robaire B, Robbins WA, Rouleau GA, Shaughnessy DT, Somers CM, Taylor JG 6th, Trasler J, Waters MD, Wilson TE, Witt KL, Bishop JB.

Mutat Res. 2013 Jan-Mar;752(1):6-9. doi: 10.1016/j.mrrev.2012.08.002. Epub 2012 Aug 28.

11.

Monitoring humans for somatic mutation in the endogenous PIG-a gene using red blood cells.

Dobrovolsky VN, Elespuru RK, Bigger CA, Robison TW, Heflich RH.

Environ Mol Mutagen. 2011 Dec;52(9):784-94. doi: 10.1002/em.20667. Epub 2011 Aug 8.

PMID:
21826740
12.

Assessment of heritable genetic effects using new genetic tools and sentinels in an era of personalized medicine.

Elespuru RK.

Environ Mol Mutagen. 2011 May;52(4):253-63. doi: 10.1002/em.20637. Epub 2011 Jan 6.

PMID:
21472782
13.

New and emerging technologies for genetic toxicity testing.

Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A Jr, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH.

Environ Mol Mutagen. 2011 Apr;52(3):205-23. doi: 10.1002/em.20614. Epub 2010 Aug 25. Review.

PMID:
20740635
14.

Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays.

Elespuru RK, Agarwal R, Atrakchi AH, Bigger CA, Heflich RH, Jagannath DR, Levy DD, Moore MM, Ouyang Y, Robison TW, Sotomayor RE, Cimino MC, Dearfield KL.

Toxicol Sci. 2009 Jun;109(2):172-9. doi: 10.1093/toxsci/kfp067. Epub 2009 Mar 31.

PMID:
19336498
15.

New approaches to assessing the effects of mutagenic agents on the integrity of the human genome.

Elespuru RK, Sankaranarayanan K.

Mutat Res. 2007 Mar 1;616(1-2):83-9. Epub 2006 Dec 15. Review.

PMID:
17174354
16.

The External RNA Controls Consortium: a progress report.

Baker SC, Bauer SR, Beyer RP, Brenton JD, Bromley B, Burrill J, Causton H, Conley MP, Elespuru R, Fero M, Foy C, Fuscoe J, Gao X, Gerhold DL, Gilles P, Goodsaid F, Guo X, Hackett J, Hockett RD, Ikonomi P, Irizarry RA, Kawasaki ES, Kaysser-Kranich T, Kerr K, Kiser G, Koch WH, Lee KY, Liu C, Liu ZL, Lucas A, Manohar CF, Miyada G, Modrusan Z, Parkes H, Puri RK, Reid L, Ryder TB, Salit M, Samaha RR, Scherf U, Sendera TJ, Setterquist RA, Shi L, Shippy R, Soriano JV, Wagar EA, Warrington JA, Williams M, Wilmer F, Wilson M, Wolber PK, Wu X, Zadro R; External RNA Controls Consortium.

Nat Methods. 2005 Oct;2(10):731-4.

PMID:
16179916
17.

Future approaches to genetic toxicology risk assessment.

Elespuru RK.

Mutat Res. 1996 Sep;365(1-3):191-204. Review.

PMID:
8898998
18.

Photoactivated gilvocarcin V induces DNA-protein crosslinking in genes for human ribosomal RNA and dihydrofolate reductase.

Matsumoto A, Fujiwara Y, Elespuru RK, Hanawalt PC.

Photochem Photobiol. 1994 Sep;60(3):225-30.

PMID:
7972373
19.

Examination of alpha-carbonyl derivatives of nitrosodimethylamine and ethylnitrosomethylamine as putative proximate carcinogens.

Elespuru RK, Saavedra JE, Kovatch RM, Lijinsky W.

Carcinogenesis. 1993 Jun;14(6):1189-93.

PMID:
8508506
20.

Mutagenicity of glyceryl trinitrate (nitroglycerin) in Salmonella typhimurium.

Maragos CM, Andrews AW, Keefer LK, Elespuru RK.

Mutat Res. 1993 Jan;298(3):187-95.

PMID:
7678153
21.

DNA deaminating ability and genotoxicity of nitric oxide and its progenitors.

Wink DA, Kasprzak KS, Maragos CM, Elespuru RK, Misra M, Dunams TM, Cebula TA, Koch WH, Andrews AW, Allen JS, et al.

Science. 1991 Nov 15;254(5034):1001-3.

PMID:
1948068
22.
23.

Inhibition of herpes virus plaquing capacity in human diploid fibroblasts treated with gilvocarcin V plus near UV radiation.

Bockstahler LE, Elespuru RK, Hitchins VM, Carney PG, Olvey KM, Lytle CD.

Photochem Photobiol. 1990 Apr;51(4):477-9.

PMID:
2160661
24.

Automation of screening assays for DNA damaging agents which induce the SOS response.

Elespuru RK.

Prog Clin Biol Res. 1990;340D:345-54. No abstract available.

PMID:
2115177
25.

An ESR study of the visible light photochemistry of gilvocarcin V.

Alegria AE, Krishna CM, Elespuru RK, Riesz P.

Photochem Photobiol. 1989 Mar;49(3):257-65.

PMID:
2543995
26.

Induction of lambda prophage near the site of focused UV laser radiation.

Matchette LS, Waynant RW, Royston DD, Hitchins VM, Elespuru RK.

Photochem Photobiol. 1989 Feb;49(2):161-7.

PMID:
2523542
27.

Photosensitized DNA breaks and DNA-to-protein crosslinks induced in human cells by antitumor agent gilvocarcin V.

Peak MJ, Peak JG, Blaumueller CM, Elespuru RK.

Chem Biol Interact. 1988;67(3-4):267-74.

PMID:
3191537
28.

Relative mutagenic and prophage-inducing effects of mono- and di-alkyl nitrosoureas.

Lijinsky W, Elespuru RK, Andrews AW.

Mutat Res. 1987 Jun;178(2):157-65.

PMID:
2953969
29.

Inducible responses to DNA damage in bacteria and mammalian cells.

Elespuru RK.

Environ Mol Mutagen. 1987;10(1):97-116. Review. No abstract available.

PMID:
2826138
30.

Wavelength dependence for the induction of bacteriophage lambda by antitumor agent gilvocarcin V.

Elespuru RK, Hitchins VM.

Photochem Photobiol. 1986 Nov;44(5):607-12. No abstract available.

PMID:
2949330
31.

Micro-BIA, a colorimetric microtiter assay of lambda prophage induction.

Elespuru RK, Moore SG.

Mutat Res. 1986 Feb;164(1):31-40.

PMID:
2936952
32.

Lack of genetic and in vitro metabolic activity of potently carcinogenic azoxyalkanes.

Lijinsky W, Andrews AW, Elespuru RK, Farrelly JG.

Mutat Res. 1985 Jul;157(1):23-7.

PMID:
3159961
33.

Activation of antitumor agent gilvocarcins by visible light.

Elespuru RK, Gonda SK.

Science. 1984 Jan 6;223(4631):69-71.

PMID:
6229029
34.
35.

Platinum complexes with anticancer potential and their evaluation by a colorimetric lambda prophage induction assay.

Das Sarma B, Daley SK, Elespuru RK.

Chem Biol Interact. 1983 Sep 1;46(2):219-32.

PMID:
6226378
36.
37.

The mutagenicity of nitrosopyrrolidine is related to its metabolism.

Hecker LI, Elespuru RK, Farrelly JG.

Mutat Res. 1979 Sep;62(2):213-20.

PMID:
388209
38.
40.

Deuterium isotope effects in mutagenesis by nitroso compounds.

Elespuru RK.

Mutat Res. 1978 Dec;54(3):265-70.

PMID:
368615
41.
42.

Mutagenicity and carcinogenicity of N-nitroso derivatives of carbamate insecticides.

Lijinsky W, Elespuru RK.

IARC Sci Publ. 1976;(14):425-8. No abstract available.

PMID:
793984
43.

Nitrosocarbaryl as a potent mutagen of environmental significance.

Elespuru R, Lijinsky W, Setlow JK.

Nature. 1974 Feb 8;247(5440):386-7. No abstract available.

PMID:
4206363
44.

The formation of carcinogenic nitroso compounds from nitrite and some types of agricultural chemicals.

Elespuru RK, Lijinsky W.

Food Cosmet Toxicol. 1973 Oct;11(5):807-17. No abstract available.

PMID:
4203521

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