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Items: 17


MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models.

Vena F, Jia R, Esfandiari A, Garcia-Gomez JJ, Rodriguez-Justo M, Ma J, Syed S, Crowley L, Elenbaas B, Goodstal S, Hartley JA, Hochhauser D.

Oncotarget. 2018 Jan 22;9(14):11592-11603. doi: 10.18632/oncotarget.24294. eCollection 2018 Feb 20.


Structure-based design of low-nanomolar PIM kinase inhibitors.

Ishchenko A, Zhang L, Le Brazidec JY, Fan J, Chong JH, Hingway A, Raditsis A, Singh L, Elenbaas B, Hong VS, Marcotte D, Silvian L, Enyedy I, Chao J.

Bioorg Med Chem Lett. 2015 Feb 1;25(3):474-80. doi: 10.1016/j.bmcl.2014.12.041. Epub 2014 Dec 19.


Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer.

Joesting MS, Perrin S, Elenbaas B, Fawell SE, Rubin JS, Franco OE, Hayward SW, Cunha GR, Marker PC.

Cancer Res. 2005 Nov 15;65(22):10423-30.


Immortalization and transformation of primary human airway epithelial cells by gene transfer.

Lundberg AS, Randell SH, Stewart SA, Elenbaas B, Hartwell KA, Brooks MW, Fleming MD, Olsen JC, Miller SW, Weinberg RA, Hahn WC.

Oncogene. 2002 Jul 4;21(29):4577-86.


Enumeration of the simian virus 40 early region elements necessary for human cell transformation.

Hahn WC, Dessain SK, Brooks MW, King JE, Elenbaas B, Sabatini DM, DeCaprio JA, Weinberg RA.

Mol Cell Biol. 2002 Apr;22(7):2111-23. Erratum in: Mol Cell Biol 2002 May;22(10):3562.


Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation.

Elenbaas B, Weinberg RA.

Exp Cell Res. 2001 Mar 10;264(1):169-84. Review.


Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, Popescu NC, Hahn WC, Weinberg RA.

Genes Dev. 2001 Jan 1;15(1):50-65.


Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling.

Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA.

Genes Dev. 2000 Mar 15;14(6):650-4.


Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis.

Marechal V, Elenbaas B, Taneyhill L, Piette J, Mechali M, Nicolas JC, Levine AJ, Moreau J.

Oncogene. 1997 Mar 27;14(12):1427-33.


Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.

Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ, Pavletich NP.

Science. 1996 Nov 8;274(5289):948-53.


The MDM2 oncoprotein binds specifically to RNA through its RING finger domain.

Elenbaas B, Dobbelstein M, Roth J, Shenk T, Levine AJ.

Mol Med. 1996 Jul;2(4):439-51.


The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes.

Marechal V, Elenbaas B, Piette J, Nicolas JC, Levine AJ.

Mol Cell Biol. 1994 Nov;14(11):7414-20.


Two upstream elements activate transcription of a major histocompatibility complex class I gene in vitro.

Driggers PH, Elenbaas BA, An JB, Lee IJ, Ozato K.

Nucleic Acids Res. 1992 May 25;20(10):2533-40.

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