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Items: 1 to 50 of 64

1.

Promoter Cre-Specific Genotyping Assays for Authentication of Cre-Driver Mouse Lines.

Couasnay G, Frey C, Elefteriou F.

JBMR Plus. 2019 Jan 18;3(4):e10128. doi: 10.1002/jbm4.10128. eCollection 2019 Apr.

2.

Shared mechanisms: osteoporosis and Alzheimer's disease?

Dengler-Crish CM, Elefteriou F.

Aging (Albany NY). 2019 Feb 19;11(5):1317-1318. doi: 10.18632/aging.101828. No abstract available.

3.

Cortical bone is an extraneuronal site of norepinephrine uptake in adult mice.

Zhu Y, Ma Y, Elefteriou F.

Bone Rep. 2018 Nov 24;9:188-198. doi: 10.1016/j.bonr.2018.11.002. eCollection 2018 Dec.

4.

PiT1/Slc20a1 Is Required for Endoplasmic Reticulum Homeostasis, Chondrocyte Survival, and Skeletal Development.

Couasnay G, Bon N, Devignes CS, Sourice S, Bianchi A, Véziers J, Weiss P, Elefteriou F, Provot S, Guicheux J, Beck-Cormier S, Beck L.

J Bone Miner Res. 2019 Feb;34(2):387-398. doi: 10.1002/jbmr.3609. Epub 2018 Nov 20.

PMID:
30347511
5.

β2ARs stimulation in osteoblasts promotes breast cancer cell adhesion to bone marrow endothelial cells in an IL-1β and selectin-dependent manner.

Clément-Demange L, Mulcrone PL, Tabarestani TQ, Sterling JA, Elefteriou F.

J Bone Oncol. 2018 Sep 8;13:1-10. doi: 10.1016/j.jbo.2018.09.002. eCollection 2018 Nov.

6.

Impact of the Autonomic Nervous System on the Skeleton.

Elefteriou F.

Physiol Rev. 2018 Jul 1;98(3):1083-1112. doi: 10.1152/physrev.00014.2017. Review.

7.

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis.

Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, Martin S, Morrison H, Pasmant E, Ratner N, Schorry E, Ullrich NJ, Viskochil D, Weiss B, Widemann BC, Zhu Y, Bakker A, Serra E.

Am J Med Genet A. 2018 May;176(5):1258-1269. doi: 10.1002/ajmg.a.38675.

8.

Dual targeting c-met and VEGFR2 in osteoblasts suppresses growth and osteolysis of prostate cancer bone metastasis.

Lee C, Whang YM, Campbell P, Mulcrone PL, Elefteriou F, Cho SW, Park SI.

Cancer Lett. 2018 Feb 1;414:205-213. doi: 10.1016/j.canlet.2017.11.016. Epub 2017 Nov 22.

PMID:
29174801
9.

The reduced osteogenic potential of Nf1-deficient osteoprogenitors is EGFR-independent.

Tahaei SE, Couasnay G, Ma Y, Paria N, Gu J, Lemoine BF, Wang X, Rios JJ, Elefteriou F.

Bone. 2018 Jan;106:103-111. doi: 10.1016/j.bone.2017.10.012. Epub 2017 Oct 12.

10.

Skeletal Colonization by Breast Cancer Cells Is Stimulated by an Osteoblast and β2AR-Dependent Neo-Angiogenic Switch.

Mulcrone PL, Campbell JP, Clément-Demange L, Anbinder AL, Merkel AR, Brekken RA, Sterling JA, Elefteriou F.

J Bone Miner Res. 2017 Jul;32(7):1442-1454. doi: 10.1002/jbmr.3133. Epub 2017 Apr 28.

11.

Role of sympathetic nerves in the establishment of metastatic breast cancer cells in bone.

Elefteriou F.

J Bone Oncol. 2016 Apr 21;5(3):132-134. eCollection 2016 Sep.

12.

The Fourth International Symposium on Genetic Disorders of the Ras/MAPK pathway.

Stevenson DA, Schill L, Schoyer L, Andresen BS, Bakker A, Bayrak-Toydemir P, Burkitt-Wright E, Chatfield K, Elefteriou F, Elgersma Y, Fisher MJ, Franz D, Gelb BD, Goriely A, Gripp KW, Hardan AY, Keppler-Noreuil KM, Kerr B, Korf B, Leoni C, McCormick F, Plotkin SR, Rauen KA, Reilly K, Roberts A, Sandler A, Siegel D, Walsh K, Widemann BC.

Am J Med Genet A. 2016 Aug;170(8):1959-66. doi: 10.1002/ajmg.a.37723. Epub 2016 May 7.

13.

Erratum to: Medication therapy for attention deficit/hyperactivity disorder is associated with lower risk of fracture: a retrospective cohort study.

Perry BA, Archer KR, Song Y, Ma Y, Green JK, Elefteriou F, Dahir KM.

Osteoporos Int. 2016 Jul;27(7):2229. doi: 10.1007/s00198-016-3569-8. No abstract available.

PMID:
26984568
14.

Medication therapy for attention deficit/hyperactivity disorder is associated with lower risk of fracture: a retrospective cohort study.

Perry BA, Archer KR, Song Y, Ma Y, Green JK, Elefteriou F, Dahir KM.

Osteoporos Int. 2016 Jul;27(7):2223-2227. doi: 10.1007/s00198-016-3547-1. Epub 2016 Feb 29. Erratum in: Osteoporos Int. 2016 Jul;27(7):2229.

PMID:
26928186
15.

The effect of an inhibitor of gut serotonin (LP533401) during the induction of periodontal disease.

Lima GM, Corazza BJ, Moraes RM, de Oliveira FE, de Oliveira LD, Franco GC, Perrien DS, Elefteriou F, Anbinder AL.

J Periodontal Res. 2016 Oct;51(5):661-8. doi: 10.1111/jre.12346. Epub 2016 Jan 6.

16.

Periodontal disease exacerbates systemic ovariectomy-induced bone loss in mice.

Anbinder AL, Moraes RM, Lima GMG, Oliveira FE, Campos DRC, Rossoni RD, Oliveira LD, Junqueira JC, Ma Y, Elefteriou F.

Bone. 2016 Feb;83:241-247. doi: 10.1016/j.bone.2015.11.014. Epub 2015 Nov 24.

PMID:
26620086
17.

TRIzol and Alu qPCR-based quantification of metastatic seeding within the skeleton.

Preston Campbell J, Mulcrone P, Masood SK, Karolak M, Merkel A, Hebron K, Zijlstra A, Sterling J, Elefteriou F.

Sci Rep. 2015 Aug 14;5:12635. doi: 10.1038/srep12635.

18.

D-amino acid inhibits biofilm but not new bone formation in an ovine model.

Harmata AJ, Ma Y, Sanchez CJ, Zienkiewicz KJ, Elefteriou F, Wenke JC, Guelcher SA.

Clin Orthop Relat Res. 2015 Dec;473(12):3951-61. doi: 10.1007/s11999-015-4465-9. Epub 2015 Jul 23.

19.

The Vestibular System: A Newly Identified Regulator of Bone Homeostasis Acting Through the Sympathetic Nervous System.

Vignaux G, Besnard S, Denise P, Elefteriou F.

Curr Osteoporos Rep. 2015 Aug;13(4):198-205. doi: 10.1007/s11914-015-0271-2. Review.

PMID:
26017583
20.

Chronic stress, sympathetic activation and skeletal metastasis of breast cancer cells.

Elefteriou F.

Bonekey Rep. 2015 May 13;4:693. doi: 10.1038/bonekey.2015.61. eCollection 2015. Review.

21.

Corrigendum: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

de la Croix Ndong J, Makowski AJ, Uppuganti S, Vignaux G, Ono K, Perrien DS, Joubert S, Baglio SR, Granchi D, Stevenson DA, Rios JJ, Nyman JS, Elefteriou F.

Nat Med. 2015 Apr;21(4):414. doi: 10.1038/nm0415-414c. No abstract available.

PMID:
25849275
22.

FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.

Karolak MR, Yang X, Elefteriou F.

Hum Mol Genet. 2015 May 1;24(9):2552-64. doi: 10.1093/hmg/ddv019. Epub 2015 Jan 23.

23.

Evaluation of somatic mutations in tibial pseudarthrosis samples in neurofibromatosis type 1.

Sant DW, Margraf RL, Stevenson DA, Grossmann AH, Viskochil DH, Hanson H, Everitt MD, Rios JJ, Elefteriou F, Hennessey T, Mao R.

J Med Genet. 2015 Apr;52(4):256-61. doi: 10.1136/jmedgenet-2014-102815. Epub 2015 Jan 22.

PMID:
25612910
24.

Inner Ear Vestibular Signals Regulate Bone Remodeling via the Sympathetic Nervous System.

Vignaux G, Ndong JD, Perrien DS, Elefteriou F.

J Bone Miner Res. 2015 Jun;30(6):1103-11. doi: 10.1002/jbmr.2426.

25.

Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx -/- mice.

de la Croix Ndong J, Stevens DM, Vignaux G, Uppuganti S, Perrien DS, Yang X, Nyman JS, Harth E, Elefteriou F.

J Bone Miner Res. 2015 Jan;30(1):55-63. doi: 10.1002/jbmr.2316. Erratum in: J Bone Miner Res. 2015 Jun;30(6):1118.

26.

Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

de la Croix Ndong J, Makowski AJ, Uppuganti S, Vignaux G, Ono K, Perrien DS, Joubert S, Baglio SR, Granchi D, Stevenson DA, Rios JJ, Nyman JS, Elefteriou F.

Nat Med. 2014 Aug;20(8):904-10. doi: 10.1038/nm.3583. Epub 2014 Jul 6. Erratum in: Nat Med. 2015 Apr;21(4):414.

27.

Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models.

Kühnisch J, Seto J, Lange C, Stumpp S, Kobus K, Grohmann J, Elefteriou F, Fratzl P, Mundlos S, Kolanczyk M.

Bone. 2014 Sep;66:155-62. doi: 10.1016/j.bone.2014.06.012. Epub 2014 Jun 17.

PMID:
24947449
28.

Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.

Kühnisch J, Seto J, Lange C, Schrof S, Stumpp S, Kobus K, Grohmann J, Kossler N, Varga P, Osswald M, Emmerich D, Tinschert S, Thielemann F, Duda G, Seifert W, El Khassawna T, Stevenson DA, Elefteriou F, Kornak U, Raum K, Fratzl P, Mundlos S, Kolanczyk M.

PLoS One. 2014 Jan 21;9(1):e86115. doi: 10.1371/journal.pone.0086115. eCollection 2014.

29.

Extracellular norepinephrine clearance by the norepinephrine transporter is required for skeletal homeostasis.

Ma Y, Krueger JJ, Redmon SN, Uppuganti S, Nyman JS, Hahn MK, Elefteriou F.

J Biol Chem. 2013 Oct 18;288(42):30105-13. doi: 10.1074/jbc.M113.481309. Epub 2013 Sep 4.

30.

Control of bone remodeling by the peripheral sympathetic nervous system.

Elefteriou F, Campbell P, Ma Y.

Calcif Tissue Int. 2014 Jan;94(1):140-51. doi: 10.1007/s00223-013-9752-4. Epub 2013 Jun 14. Review.

31.

The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.

Ono K, Karolak MR, Ndong Jde L, Wang W, Yang X, Elefteriou F.

Hum Mol Genet. 2013 Aug 1;22(15):3048-62. doi: 10.1093/hmg/ddt162. Epub 2013 Apr 9.

32.

Bone remodeling is regulated by inner ear vestibular signals.

Vignaux G, Besnard S, Ndong J, Philoxène B, Denise P, Elefteriou F.

J Bone Miner Res. 2013 Oct;28(10):2136-44. doi: 10.1002/jbmr.1940.

33.

Approaches to treating NF1 tibial pseudarthrosis: consensus from the Children's Tumor Foundation NF1 Bone Abnormalities Consortium.

Stevenson DA, Little D, Armstrong L, Crawford AH, Eastwood D, Friedman JM, Greggi T, Gutierrez G, Hunter-Schaedle K, Kendler DL, Kolanczyk M, Monsell F, Oetgen M, Richards BS, Schindeler A, Schorry EK, Wilkes D, Viskochil DH, Yang FC, Elefteriou F.

J Pediatr Orthop. 2013 Apr-May;33(3):269-75. doi: 10.1097/BPO.0b013e31828121b8. Review.

PMID:
23482262
34.

Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.

Edwards JR, Perrien DS, Fleming N, Nyman JS, Ono K, Connelly L, Moore MM, Lwin ST, Yull FE, Mundy GR, Elefteriou F.

J Bone Miner Res. 2013 Apr;28(4):960-9. doi: 10.1002/jbmr.1824.

35.

Models of bone metastasis.

Campbell JP, Merkel AR, Masood-Campbell SK, Elefteriou F, Sterling JA.

J Vis Exp. 2012 Sep 4;(67):e4260. doi: 10.3791/4260.

36.

Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice.

Campbell JP, Karolak MR, Ma Y, Perrien DS, Masood-Campbell SK, Penner NL, Munoz SA, Zijlstra A, Yang X, Sterling JA, Elefteriou F.

PLoS Biol. 2012 Jul;10(7):e1001363. doi: 10.1371/journal.pbio.1001363. Epub 2012 Jul 17.

37.

Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh.

Wang W, Lian N, Ma Y, Li L, Gallant RC, Elefteriou F, Yang X.

Development. 2012 Feb;139(3):601-11. doi: 10.1242/dev.069575. Epub 2011 Dec 21.

38.

Genetic mouse models for bone studies--strengths and limitations.

Elefteriou F, Yang X.

Bone. 2011 Dec;49(6):1242-54. doi: 10.1016/j.bone.2011.08.021. Epub 2011 Aug 31. Review.

39.

Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.

Wang W, Nyman JS, Ono K, Stevenson DA, Yang X, Elefteriou F.

Hum Mol Genet. 2011 Oct 15;20(20):3910-24. doi: 10.1093/hmg/ddr310. Epub 2011 Jul 14.

40.

β2-Adrenergic receptor signaling in osteoblasts contributes to the catabolic effect of glucocorticoids on bone.

Ma Y, Nyman JS, Tao H, Moss HH, Yang X, Elefteriou F.

Endocrinology. 2011 Apr;152(4):1412-22. doi: 10.1210/en.2010-0881. Epub 2011 Jan 25.

41.

Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.

Wang W, Nyman JS, Moss HE, Gutierrez G, Mundy GR, Yang X, Elefteriou F.

J Bone Miner Res. 2010 Jul;25(7):1658-67. doi: 10.1002/jbmr.42.

42.

Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.

Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X.

Development. 2009 Dec;136(24):4143-53. doi: 10.1242/dev.043281. Epub 2009 Nov 11.

43.

Skeletal abnormalities in neurofibromatosis type 1: approaches to therapeutic options.

Elefteriou F, Kolanczyk M, Schindeler A, Viskochil DH, Hock JM, Schorry EK, Crawford AH, Friedman JM, Little D, Peltonen J, Carey JC, Feldman D, Yu X, Armstrong L, Birch P, Kendler DL, Mundlos S, Yang FC, Agiostratidou G, Hunter-Schaedle K, Stevenson DA.

Am J Med Genet A. 2009 Oct;149A(10):2327-38. doi: 10.1002/ajmg.a.33045. Review.

PMID:
19764036
44.

Vimentin inhibits ATF4-mediated osteocalcin transcription and osteoblast differentiation.

Lian N, Wang W, Li L, Elefteriou F, Yang X.

J Biol Chem. 2009 Oct 30;284(44):30518-25. doi: 10.1074/jbc.M109.052373. Epub 2009 Sep 2.

45.

Cocaine and amphetamine-regulated transcript may regulate bone remodeling as a circulating molecule.

Singh MK, Elefteriou F, Karsenty G.

Endocrinology. 2008 Aug;149(8):3933-41. doi: 10.1210/en.2008-0109. Epub 2008 May 1.

46.

Regulation of bone remodeling by the central and peripheral nervous system.

Elefteriou F.

Arch Biochem Biophys. 2008 May 15;473(2):231-6. doi: 10.1016/j.abb.2008.03.016. Epub 2008 Mar 23. Review.

47.

The new field of neuroskeletal biology.

Patel MS, Elefteriou F.

Calcif Tissue Int. 2007 May;80(5):337-47. Epub 2007 Apr 18. Review. Erratum in: Calcif Tissue Int. 2007 Sep;81(3):247.

PMID:
17440766
48.

ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.

Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G.

Cell Metab. 2006 Dec;4(6):441-51.

49.

Boning up on ephrin signaling.

Mundy GR, Elefteriou F.

Cell. 2006 Aug 11;126(3):441-3. Review.

50.

Neuronal signaling and the regulation of bone remodeling.

Elefteriou F.

Cell Mol Life Sci. 2005 Oct;62(19-20):2339-49. Review.

PMID:
16132233

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