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Items: 34


Lineage specific histories of Mycobacterium tuberculosis dispersal in Africa and Eurasia.

O'Neill MB, Shockey A, Zarley A, Aylward W, Eldholm V, Kitchen A, Pepperell CS.

Mol Ecol. 2019 Jul;28(13):3241-3256. doi: 10.1111/mec.15120. Epub 2019 Jul 9.


Rapid phenotypic evolution in multidrug-resistant Klebsiella pneumoniae hospital outbreak strains.

van Dorp L, Wang Q, Shaw LP, Acman M, Brynildsrud OB, Eldholm V, Wang R, Gao H, Yin Y, Chen H, Ding C, Farrer RA, Didelot X, Balloux F, Wang H.

Microb Genom. 2019 Apr;5(4). doi: 10.1099/mgen.0.000263. Epub 2019 Apr 2.


Transmission of drug-resistant tuberculosis in HIV-endemic settings.

Khan PY, Yates TA, Osman M, Warren RM, van der Heijden Y, Padayatchi N, Nardell EA, Moore D, Mathema B, Gandhi N, Eldholm V, Dheda K, Hesseling AC, Mizrahi V, Rustomjee R, Pym A.

Lancet Infect Dis. 2019 Mar;19(3):e77-e88. doi: 10.1016/S1473-3099(18)30537-1. Epub 2018 Dec 13. Review. Erratum in: Lancet Infect Dis. 2019 Mar 6;:.


Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation.

Brynildsrud OB, Pepperell CS, Suffys P, Grandjean L, Monteserin J, Debech N, Bohlin J, Alfsnes K, Pettersson JO, Kirkeleite I, Fandinho F, da Silva MA, Perdigao J, Portugal I, Viveiros M, Clark T, Caws M, Dunstan S, Thai PVK, Lopez B, Ritacco V, Kitchen A, Brown TS, van Soolingen D, O'Neill MB, Holt KE, Feil EJ, Mathema B, Balloux F, Eldholm V.

Sci Adv. 2018 Oct 17;4(10):eaat5869. doi: 10.1126/sciadv.aat5869. eCollection 2018 Oct.


A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis.

Alfsnes K, Frye SA, Eriksson J, Eldholm V, Brynildsrud OB, Bohlin J, Harrison OB, Hood DW, Maiden MCJ, Tønjum T, Ambur OH.

Microb Genom. 2018 Nov;4(11). doi: 10.1099/mgen.0.000222. Epub 2018 Sep 25.


Genome-based transmission modelling separates imported tuberculosis from recent transmission within an immigrant population.

Ayabina D, Ronning JO, Alfsnes K, Debech N, Brynildsrud OB, Arnesen T, Norheim G, Mengshoel AT, Rykkvin R, Dahle UR, Colijn C, Eldholm V.

Microb Genom. 2018 Oct;4(10). doi: 10.1099/mgen.0.000219. Epub 2018 Sep 14.


From Theory to Practice: Translating Whole-Genome Sequencing (WGS) into the Clinic.

Balloux F, Brønstad Brynildsrud O, van Dorp L, Shaw LP, Chen H, Harris KA, Wang H, Eldholm V.

Trends Microbiol. 2018 Dec;26(12):1035-1048. doi: 10.1016/j.tim.2018.08.004. Epub 2018 Sep 4. Review.


Modeling of the GC content of the substituted bases in bacterial core genomes.

Bohlin J, Eldholm V, Brynildsrud O, Petterson JH, Alfsnes K.

BMC Genomics. 2018 Aug 6;19(1):589. doi: 10.1186/s12864-018-4984-3.


Re-visiting the evolution, dispersal and epidemiology of Zika virus in Asia.

Pettersson JH, Bohlin J, Dupont-Rouzeyrol M, Brynildsrud OB, Alfsnes K, Cao-Lormeau VM, Gaunt MW, Falconar AK, de Lamballerie X, Eldholm V, Musso D, Gould EA.

Emerg Microbes Infect. 2018 May 9;7(1):79. doi: 10.1038/s41426-018-0082-5.


Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa.

Brynildsrud OB, Eldholm V, Bohlin J, Uadiale K, Obaro S, Caugant DA.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):5510-5515. doi: 10.1073/pnas.1802298115. Epub 2018 May 7.


Erratum for Pettersson et al., "How Did Zika Virus Emerge in the Pacific Islands and Latin America?"

Pettersson JH, Eldholm V, Seligman SJ, Lundkvist Å, Falconar AK, Gaunt MW, Musso D, Nougairède A, Charrel R, Gould EA, de Lamballerie X.

MBio. 2018 Mar 20;9(2). pii: e00386-18. doi: 10.1128/mBio.00386-18. No abstract available.


Whole-Transcriptome and -Genome Analysis of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates Identifies Downregulation of ethA as a Mechanism of Ethionamide Resistance.

de Welzen L, Eldholm V, Maharaj K, Manson AL, Earl AM, Pym AS.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01461-17. doi: 10.1128/AAC.01461-17. Print 2017 Dec.


Characterizing the virome of Ixodes ricinus ticks from northern Europe.

Pettersson JH, Shi M, Bohlin J, Eldholm V, Brynildsrud OB, Paulsen KM, Andreassen Å, Holmes EC.

Sci Rep. 2017 Sep 7;7(1):10870. doi: 10.1038/s41598-017-11439-y.


Tuberculosis Outbreak in an Educational Institution in Norway.

Norheim G, Seterelv S, Arnesen TM, Mengshoel AT, Tønjum T, Rønning JO, Eldholm V.

J Clin Microbiol. 2017 May;55(5):1327-1333. doi: 10.1128/JCM.01152-16. Epub 2017 Feb 15.


The nucleotide composition of microbial genomes indicates differential patterns of selection on core and accessory genomes.

Bohlin J, Eldholm V, Pettersson JH, Brynildsrud O, Snipen L.

BMC Genomics. 2017 Feb 10;18(1):151. doi: 10.1186/s12864-017-3543-7.


[Tattooed norwegian tourist with fever and rashes].

Bø K, Skullerud KH, Mengshoel AT, Eldholm V, Brantsæter AB.

Tidsskr Nor Laegeforen. 2017 Feb 7;137(3):205-207. doi: 10.4045/tidsskr.16.0710. eCollection 2017 Feb. Norwegian. No abstract available.


Erratum to: Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary.

Brynildsrud O, Bohlin J, Scheffer L, Eldholm V.

Genome Biol. 2016 Dec 19;17(1):262. No abstract available.


Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary.

Brynildsrud O, Bohlin J, Scheffer L, Eldholm V.

Genome Biol. 2016 Nov 25;17(1):238. Erratum in: Genome Biol. 2016 Dec 19;17 (1):262.


Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis.

Eldholm V, Pettersson JH, Brynildsrud OB, Kitchen A, Rasmussen EM, Lillebaek T, Rønning JO, Crudu V, Mengshoel AT, Debech N, Alfsnes K, Bohlin J, Pepperell CS, Balloux F.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13881-13886. Epub 2016 Nov 21.


How Did Zika Virus Emerge in the Pacific Islands and Latin America?

Pettersson JH, Eldholm V, Seligman SJ, Lundkvist Å, Falconar AK, Gaunt MW, Musso D, Nougairède A, Charrel R, Gould EA, de Lamballerie X.

MBio. 2016 Oct 11;7(5). pii: e01239-16. doi: 10.1128/mBio.01239-16. Erratum in: MBio. 2018 Mar 20;9(2):.


Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis.

Eldholm V, Rieux A, Monteserin J, Lopez JM, Palmero D, Lopez B, Ritacco V, Didelot X, Balloux F.

Elife. 2016 Aug 9;5. pii: e16644. doi: 10.7554/eLife.16644.


Antimicrobial Resistance in Mycobacterium tuberculosis: The Odd One Out.

Eldholm V, Balloux F.

Trends Microbiol. 2016 Aug;24(8):637-648. doi: 10.1016/j.tim.2016.03.007. Epub 2016 Apr 7. Review.


Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain.

Eldholm V, Monteserin J, Rieux A, Lopez B, Sobkowiak B, Ritacco V, Balloux F.

Nat Commun. 2015 May 11;6:7119. doi: 10.1038/ncomms8119.


Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient.

Eldholm V, Norheim G, von der Lippe B, Kinander W, Dahle UR, Caugant DA, Mannsåker T, Mengshoel AT, Dyrhol-Riise AM, Balloux F.

Genome Biol. 2014 Nov 7;15(11):490. doi: 10.1186/s13059-014-0490-3.


CTCF mediates the TERT enhancer-promoter interactions in lung cancer cells: identification of a novel enhancer region involved in the regulation of TERT gene.

Eldholm V, Haugen A, Zienolddiny S.

Int J Cancer. 2014 May 15;134(10):2305-13. doi: 10.1002/ijc.28570. Epub 2013 Nov 14.


Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.

Chymkowitch P, Eldholm V, Lorenz S, Zimmermann C, Lindvall JM, Bjørås M, Meza-Zepeda LA, Enserink JM.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10450-5. doi: 10.1073/pnas.1200067109. Epub 2012 Jun 11.


A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.

Zimmermann C, Chymkowitch P, Eldholm V, Putnam CD, Lindvall JM, Omerzu M, Bjørås M, Kolodner RD, Enserink JM.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18748-53. doi: 10.1073/pnas.1115885108. Epub 2011 Oct 31.


Pneumococcal CbpD is a murein hydrolase that requires a dual cell envelope binding specificity to kill target cells during fratricide.

Eldholm V, Johnsborg O, Straume D, Ohnstad HS, Berg KH, Hermoso JA, Håvarstein LS.

Mol Microbiol. 2010 May;76(4):905-17. doi: 10.1111/j.1365-2958.2010.07143.x. Epub 2010 Mar 25.


The pneumococcal cell envelope stress-sensing system LiaFSR is activated by murein hydrolases and lipid II-interacting antibiotics.

Eldholm V, Gutt B, Johnsborg O, Brückner R, Maurer P, Hakenbeck R, Mascher T, Håvarstein LS.

J Bacteriol. 2010 Apr;192(7):1761-73. doi: 10.1128/JB.01489-09. Epub 2010 Jan 29.


Fratricide in Streptococcus pneumoniae: contributions and role of the cell wall hydrolases CbpD, LytA and LytC.

Eldholm V, Johnsborg O, Haugen K, Ohnstad HS, Håvarstein LS.

Microbiology. 2009 Jul;155(Pt 7):2223-34. doi: 10.1099/mic.0.026328-0. Epub 2009 Apr 23.


A predatory mechanism dramatically increases the efficiency of lateral gene transfer in Streptococcus pneumoniae and related commensal species.

Johnsborg O, Eldholm V, Bjørnstad ML, Håvarstein LS.

Mol Microbiol. 2008 Jul;69(1):245-53. doi: 10.1111/j.1365-2958.2008.06288.x. Epub 2008 May 15.


Natural genetic transformation: prevalence, mechanisms and function.

Johnsborg O, Eldholm V, Håvarstein LS.

Res Microbiol. 2007 Dec;158(10):767-78. Epub 2007 Oct 2. Review.


Impact of immigration on the molecular epidemiology of Mycobacterium tuberculosis in a low-incidence country.

Dahle UR, Eldholm V, Winje BA, Mannsåker T, Heldal E.

Am J Respir Crit Care Med. 2007 Nov 1;176(9):930-5. Epub 2007 Aug 2.


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