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Items: 1 to 50 of 228

1.

Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers.

Mahdy HA, Ibrahim MK, Metwaly AM, Belal A, Mehany ABM, El-Gamal KMA, El-Sharkawy A, Elhendawy MA, Radwan MM, Elsohly MA, Eissa IH.

Bioorg Chem. 2020 Jan;94:103422. doi: 10.1016/j.bioorg.2019.103422. Epub 2019 Nov 12.

PMID:
31812261
2.

Δ9-Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits.

Taskar PS, Patil A, Lakhani P, Ashour E, Gul W, ElSohly MA, Murphy B, Majumdar S.

Transl Vis Sci Technol. 2019 Sep 19;8(5):15. doi: 10.1167/tvst.8.5.15. eCollection 2019 Sep.

3.

Role of Cannabinoids and Terpenes in Cannabis-Mediated Analgesia in Rats.

Harris HM, Rousseau MA, Wanas AS, Radwan MM, Caldwell S, Sufka KJ, ElSohly MA.

Cannabis Cannabinoid Res. 2019 Sep 23;4(3):177-182. doi: 10.1089/can.2018.0054. eCollection 2019.

PMID:
31579834
4.

Priority Considerations for Medicinal Cannabis-Related Research.

Bonn-Miller MO, Pollack CV Jr, Casarett D, Dart R, ElSohly M, Good L, Guzmán M, Hanuš L, Hill KP, Huestis MA, Marsh E, Sisley S, Skinner N, Spahr J, Vandrey R, Viscusi E, Ware MA, Abrams D.

Cannabis Cannabinoid Res. 2019 Sep 23;4(3):139-157. doi: 10.1089/can.2019.0045. eCollection 2019. No abstract available.

PMID:
31579832
5.

Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.

Eissa IH, Metwaly AM, Belal A, Mehany ABM, Ayyad RR, El-Adl K, Mahdy HA, Taghour MS, El-Gamal KMA, El-Sawah ME, Elmetwally SA, Elhendawy MA, Radwan MM, ElSohly MA.

Arch Pharm (Weinheim). 2019 Nov;352(11):e1900123. doi: 10.1002/ardp.201900123. Epub 2019 Aug 29.

PMID:
31463953
6.

Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration.

Ewing LE, McGill MR, Yee EU, Quick CM, Skinner CM, Kennon-McGill S, Clemens M, Vazquez JH, McCullough SS, Williams DK, Kutanzi KR, Walker LA, ElSohly MA, James LP, Gurley BJ, Koturbash I.

Molecules. 2019 Jun 17;24(12). pii: E2256. doi: 10.3390/molecules24122256.

7.

Correction to: New trends in cannabis potency in USA and Europe during the last decade (2008-2017).

Chandra S, Radwan MM, Majumdar CG, Church JC, Freeman TP, ElSohly MA.

Eur Arch Psychiatry Clin Neurosci. 2019 Dec;269(8):997. doi: 10.1007/s00406-019-01020-1.

PMID:
31123822
8.

Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model.

Ewing LE, Skinner CM, Quick CM, Kennon-McGill S, McGill MR, Walker LA, ElSohly MA, Gurley BJ, Koturbash I.

Molecules. 2019 Apr 30;24(9). pii: E1694. doi: 10.3390/molecules24091694.

9.

Poison Ivy, Oak, and Sumac Dermatitis: What Is Known and What Is New?

Kim Y, Flamm A, ElSohly MA, Kaplan DH, Hage RJ Jr, Hamann CP, Marks JG Jr.

Dermatitis. 2019 May/Jun;30(3):183-190. doi: 10.1097/DER.0000000000000472.

PMID:
31045932
10.

Analog Derivatization of Cannabidiol for Improved Ocular Permeation.

Taskar P, Adelli G, Patil A, Lakhani P, Ashour E, Gul W, ElSohly M, Majumdar S.

J Ocul Pharmacol Ther. 2019 Jun;35(5):301-310. doi: 10.1089/jop.2018.0141. Epub 2019 Apr 18.

PMID:
30998110
11.

New trends in cannabis potency in USA and Europe during the last decade (2008-2017).

Chandra S, Radwan MM, Majumdar CG, Church JC, Freeman TP, ElSohly MA.

Eur Arch Psychiatry Clin Neurosci. 2019 Feb;269(1):5-15. doi: 10.1007/s00406-019-00983-5. Epub 2019 Jan 22. Erratum in: Eur Arch Psychiatry Clin Neurosci. 2019 May 23;:.

PMID:
30671616
12.

Analysis of Terpenes in Cannabis sativa L. Using GC/MS: Method Development, Validation, and Application.

Ibrahim EA, Wang M, Radwan MM, Wanas AS, Majumdar CG, Avula B, Wang YH, Khan IA, Chandra S, Lata H, Hadad GM, Abdel Salam RA, Ibrahim AK, Ahmed SA, ElSohly MA.

Planta Med. 2019 Mar;85(5):431-438. doi: 10.1055/a-0828-8387. Epub 2019 Jan 15.

PMID:
30646402
13.

Chemical constituents, Antibacterial and Acetylcholine esterase inhibitory activity of Cupressus macrocarpa leaves.

Harraz FM, Hammoda HM, El-Hawiet A, Radwan MM, Wanas AS, Eid AM, ElSohly MA.

Nat Prod Res. 2018 Nov 6:1-7. doi: 10.1080/14786419.2018.1508140. [Epub ahead of print]

PMID:
30398365
14.

Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro™ (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments.

Skinner CM, Miousse IR, Ewing LE, Sridharan V, Cao M, Lin H, Williams DK, Avula B, Haider S, Chittiboyina AG, Khan IA, ElSohly MA, Boerma M, Gurley BJ, Koturbash I.

Food Chem Toxicol. 2018 Dec;122:21-32. doi: 10.1016/j.fct.2018.09.067. Epub 2018 Sep 30.

15.

Marijuana's Effects on Brain Structure and Function: What Do We Know and What Should We Do? A Brief Review and Commentary.

deShazo RD, Parker SB, Williams D, Ingram JB, Elsohly M, Rodenmeyer K, McCullouch K.

Am J Med. 2019 Mar;132(3):281-285. doi: 10.1016/j.amjmed.2018.09.006. Epub 2018 Sep 18. Review.

PMID:
30240677
16.

Cannabis and cannabinoid drug development: evaluating botanical versus single molecule approaches.

Bonn-Miller MO, ElSohly MA, Loflin MJE, Chandra S, Vandrey R.

Int Rev Psychiatry. 2018 Jun;30(3):277-284. doi: 10.1080/09540261.2018.1474730.

17.

Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry.

Avula B, Tekwani BL, Chaurasiya ND, Fasinu P, Dhammika Nanayakkara NP, Bhandara Herath HMT, Wang YH, Bae JY, Khan SI, Elsohly MA, McChesney JD, Zimmerman PA, Khan IA, Walker LA.

Malar J. 2018 Aug 13;17(1):294. doi: 10.1186/s12936-018-2433-z.

18.

LC-MS-MS Method Development and Analysis of Stimulants, Opiates, Synthetic Opiates, PCP, and Benzodiazepines in Wastewater. Preponderance of these Drugs During Football Games.

Gul W, Gul SW, Stamper B, Godfrey M, ElSohly MA.

Methods Mol Biol. 2018;1810:149-182. doi: 10.1007/978-1-4939-8579-1_15.

PMID:
29974427
19.

Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.

Ibrahim MK, Taghour MS, Metwaly AM, Belal A, Mehany ABM, Elhendawy MA, Radwan MM, Yassin AM, El-Deeb NM, Hafez EE, ElSohly MA, Eissa IH.

Eur J Med Chem. 2018 Jul 15;155:117-134. doi: 10.1016/j.ejmech.2018.06.004. Epub 2018 Jun 4.

PMID:
29885574
20.

Urushiol Patch Test Using the T.R.U.E. TEST System.

Kim Y, Longenecker A, ElSohly MA, Gul W, Hage RJ Jr, Hamann CP, Marks JG Jr.

Dermatitis. 2018 May/Jun;29(3):127-131. doi: 10.1097/DER.0000000000000360.

PMID:
29762206
21.

Bioactivity-Guided Isolation of Potential Antidiabetic and Antihyperlipidemic Compounds from Trigonella stellata.

Shams Eldin SM, Radwan MM, Wanas AS, Habib AM, Kassem FF, Hammoda HM, Khan SI, Klein ML, Elokely KM, ElSohly MA.

J Nat Prod. 2018 May 25;81(5):1154-1161. doi: 10.1021/acs.jnatprod.7b00707. Epub 2018 Apr 20.

PMID:
29676912
22.

Detection and Quantification of Cannabinoids in Extracts of Cannabis sativa Roots Using LC-MS/MS.

Gul W, Gul SW, Chandra S, Lata H, Ibrahim EA, ElSohly MA.

Planta Med. 2018 Mar;84(4):267-271. doi: 10.1055/s-0044-100798. Epub 2018 Jan 22.

PMID:
29359294
23.

Quantitative Determination of Δ9-THC, CBG, CBD, Their Acid Precursors and Five Other Neutral Cannabinoids by UHPLC-UV-MS.

Wang YH, Avula B, ElSohly MA, Radwan MM, Wang M, Wanas AS, Mehmedic Z, Khan IA.

Planta Med. 2018 Mar;84(4):260-266. doi: 10.1055/s-0043-124873. Epub 2017 Dec 20.

PMID:
29262425
24.

Determination of Acid and Neutral Cannabinoids in Extracts of Different Strains of Cannabis sativa Using GC-FID.

Ibrahim EA, Gul W, Gul SW, Stamper BJ, Hadad GM, Abdel Salam RA, Ibrahim AK, Ahmed SA, Chandra S, Lata H, Radwan MM, ElSohly MA.

Planta Med. 2018 Mar;84(4):250-259. doi: 10.1055/s-0043-124088. Epub 2017 Dec 13.

PMID:
29237190
25.

Bioactive products from singlet oxygen photooxygenation of cannabinoids.

Galal Osman A, Elokely KM, Yadav VK, Carvalho P, Radwan M, Slade D, Gul W, Khan S, Dale OR, Husni AS, Klein ML, Cutler SJ, Ross SA, ElSohly MA.

Eur J Med Chem. 2018 Jan 1;143:983-996. doi: 10.1016/j.ejmech.2017.11.043. Epub 2017 Nov 21.

PMID:
29232588
26.

Decarboxylation Study of Acidic Cannabinoids: A Novel Approach Using Ultra-High-Performance Supercritical Fluid Chromatography/Photodiode Array-Mass Spectrometry.

Wang M, Wang YH, Avula B, Radwan MM, Wanas AS, van Antwerp J, Parcher JF, ElSohly MA, Khan IA.

Cannabis Cannabinoid Res. 2016 Dec 1;1(1):262-271. doi: 10.1089/can.2016.0020. eCollection 2016.

27.

Safety assessment of the dietary supplement OxyELITE™ Pro (New Formula) in inbred and outbred mouse strains.

Miousse IR, Skinner CM, Lin H, Ewing LE, Kosanke SD, Williams DK, Avula B, Khan IA, ElSohly MA, Gurley BJ, Koturbash I.

Food Chem Toxicol. 2017 Nov;109(Pt 1):194-209. doi: 10.1016/j.fct.2017.08.025. Epub 2017 Aug 24.

28.

Effects of Cannabidiol on Morphine Conditioned Place Preference in Mice.

Markos JR, Harris HM, Gul W, ElSohly MA, Sufka KJ.

Planta Med. 2018 Mar;84(4):221-224. doi: 10.1055/s-0043-117838. Epub 2017 Aug 9.

PMID:
28793355
29.

Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of quinazolin-4(3H)-one derivatives as potential PPARγ and SUR agonists.

Ibrahim MK, Eissa IH, Alesawy MS, Metwaly AM, Radwan MM, ElSohly MA.

Bioorg Med Chem. 2017 Sep 1;25(17):4723-4744. doi: 10.1016/j.bmc.2017.07.015. Epub 2017 Jul 8.

PMID:
28720328
30.

Flavonoids of Alcea rosea L. and their immune stimulant, antioxidant and cytotoxic activities on hepatocellular carcinoma HepG-2 cell line.

Abdel-Salam NA, Ghazy NM, Sallam SM, Radwan MM, Wanas AS, ElSohly MA, El-Demellawy MA, Abdel-Rahman NM, Piacente S, Shenouda ML.

Nat Prod Res. 2018 Mar;32(6):702-706. doi: 10.1080/14786419.2017.1332602. Epub 2017 Jun 5.

PMID:
28580799
31.

Development of a Δ9-Tetrahydrocannabinol Amino Acid-Dicarboxylate Prodrug With Improved Ocular Bioavailability.

Adelli GR, Bhagav P, Taskar P, Hingorani T, Pettaway S, Gul W, ElSohly MA, Repka MA, Majumdar S.

Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2167-2179. doi: 10.1167/iovs.16-20757.

32.

Cannabis cultivation: Methodological issues for obtaining medical-grade product.

Chandra S, Lata H, ElSohly MA, Walker LA, Potter D.

Epilepsy Behav. 2017 May;70(Pt B):302-312. doi: 10.1016/j.yebeh.2016.11.029. Epub 2017 Feb 13. Review.

PMID:
28202406
33.

Phytochemistry of Cannabis sativa L.

ElSohly MA, Radwan MM, Gul W, Chandra S, Galal A.

Prog Chem Org Nat Prod. 2017;103:1-36. doi: 10.1007/978-3-319-45541-9_1. Review.

PMID:
28120229
34.

Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPARγ and SUR agonists.

Ibrahim MK, Eissa IH, Abdallah AE, Metwaly AM, Radwan MM, ElSohly MA.

Bioorg Med Chem. 2017 Feb 15;25(4):1496-1513. doi: 10.1016/j.bmc.2017.01.015. Epub 2017 Jan 16.

PMID:
28117121
35.

LC-MS-MS Method for Analysis of Benzodiazepines in Wastewater During Football Games IV.

Stamper B, Gul W, Godfrey M, Gul SW, ElSohly MA.

J Anal Toxicol. 2017 Apr 1;41(3):205-213. doi: 10.1093/jat/bkw122.

PMID:
27979928
36.

Quantitative Determination of Cannabinoids in Cannabis and Cannabis Products Using Ultra-High-Performance Supercritical Fluid Chromatography and Diode Array/Mass Spectrometric Detection.

Wang M, Wang YH, Avula B, Radwan MM, Wanas AS, Mehmedic Z, van Antwerp J, ElSohly MA, Khan IA.

J Forensic Sci. 2017 May;62(3):602-611. doi: 10.1111/1556-4029.13341. Epub 2016 Dec 13.

PMID:
27957741
37.

Ocular Disposition of ∆8-Tetrahydrocannabinol from Various Topical Ophthalmic Formulations.

Punyamurthula NS, Adelli GR, Gul W, Repka MA, ElSohly MA, Majumdar S.

AAPS PharmSciTech. 2017 Aug;18(6):1936-1945. doi: 10.1208/s12249-016-0672-2. Epub 2016 Nov 30.

38.

Cornigerin, a new sesqui-lignan from the hepatoprotective fractions of Cynara cornigera L.

El Sohafy SM, Metwally AM, Omar AA, Amer ME, Radwan MM, Abdel-Kader MS, El Toumy SA, ElSohly MA.

Fitoterapia. 2016 Dec;115:101-105. doi: 10.1016/j.fitote.2016.09.015. Epub 2016 Sep 28.

PMID:
27693744
39.

LC-MS-MS Method for the Analysis of Miscellaneous Drugs in Wastewater During Football Games III.

Stamper B, Gul W, Godfrey M, Gul SW, ElSohly MA.

J Anal Toxicol. 2016 Oct;40(8):694-699. Epub 2016 Aug 25.

PMID:
27562966
40.

Current Status and Prospects for Cannabidiol Preparations as New Therapeutic Agents.

Fasinu PS, Phillips S, ElSohly MA, Walker LA.

Pharmacotherapy. 2016 Jul;36(7):781-96. doi: 10.1002/phar.1780. Review.

PMID:
27285147
41.

Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Cisplatin-Induced Neuropathy in Mice.

Harris HM, Sufka KJ, Gul W, ElSohly MA.

Planta Med. 2016 Aug;82(13):1169-72. doi: 10.1055/s-0042-106303. Epub 2016 May 23.

PMID:
27214593
42.

In Vitro Propagation of Cannabis sativa L. and Evaluation of Regenerated Plants for Genetic Fidelity and Cannabinoids Content for Quality Assurance.

Lata H, Chandra S, Khan IA, ElSohly MA.

Methods Mol Biol. 2016;1391:275-88. doi: 10.1007/978-1-4939-3332-7_19.

PMID:
27108324
43.

Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes.

Fasinu PS, Avula B, Tekwani BL, Nanayakkara NP, Wang YH, Bandara Herath HM, McChesney JD, Reichard GA, Marcsisin SR, Elsohly MA, Khan SI, Khan IA, Walker LA.

Malar J. 2016 Apr 19;15:224. doi: 10.1186/s12936-016-1270-1.

44.

Tandem Mass Spectrometry for Structural Identification of Sesquiterpene Alkaloids from the Stems of Dendrobium nobile Using LC-QToF.

Wang YH, Avula B, Abe N, Wei F, Wang M, Ma SC, Ali Z, Elsohly MA, Khan IA.

Planta Med. 2016 May;82(7):662-70. doi: 10.1055/s-0042-103031. Epub 2016 Apr 7.

PMID:
27054915
45.

LC-MS-MS Method for Analysis of Opiates in Wastewater During Football Games II.

Gul W, Stamper B, Godfrey M, Gul SW, ElSohly MA.

J Anal Toxicol. 2016 Jun;40(5):330-7. doi: 10.1093/jat/bkw022. Epub 2016 Apr 6.

PMID:
27052850
46.

Changes in Cannabis Potency Over the Last 2 Decades (1995-2014): Analysis of Current Data in the United States.

ElSohly MA, Mehmedic Z, Foster S, Gon C, Chandra S, Church JC.

Biol Psychiatry. 2016 Apr 1;79(7):613-9. doi: 10.1016/j.biopsych.2016.01.004. Epub 2016 Jan 19.

47.

Crystal structure of (9S,10S)-10-eth-oxy-9-hy-droxy-6,6,9-trimethyl-3-pentyl-7,8,9,10-tetra-hydro-6H-benzo[c]chromen-1-yl 4-methyl-benzene-sulfonate.

Gul W, Galal A, ElSohly MA, Carvalho P.

Acta Crystallogr E Crystallogr Commun. 2015 Dec 24;71(Pt 12):o1082-3. doi: 10.1107/S2056989015024044. eCollection 2015 Dec 1.

48.

Determination of 11 Cannabinoids in Biomass and Extracts of Different Varieties of Cannabis Using High-Performance Liquid Chromatography.

Gul W, Gul SW, Radwan MM, Wanas AS, Mehmedic Z, Khan II, Sharaf MH, ElSohly MA.

J AOAC Int. 2015 Nov-Dec;98(6):1523-8. doi: 10.5740/jaoacint.15-095.

PMID:
26651563
49.

Controlled release tablet formulation containing natural Δ(9)-tetrahydrocannabinol.

Punyamurthula NS, Hingorani T, Adelli G, Gul W, ElSohly MA, Repka MA, Majumdar S.

Drug Dev Ind Pharm. 2016;42(7):1158-64. doi: 10.3109/03639045.2015.1118490. Epub 2015 Dec 7.

50.

Mechanism of action of antiepileptic ceramide from Red Sea soft coral Sarcophyton auritum.

Eltahawy NA, Ibrahim AK, Radwan MM, Zaitone SA, Gomaa M, ElSohly MA, Hassanean HA, Ahmed SA.

Bioorg Med Chem Lett. 2015 Dec 15;25(24):5819-24. doi: 10.1016/j.bmcl.2015.08.039.

PMID:
26577694

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