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Items: 4


Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells.

Benjamin D, Robay D, Hindupur SK, Pohlmann J, Colombi M, El-Shemerly MY, Maira SM, Moroni C, Lane HA, Hall MN.

Cell Rep. 2018 Dec 11;25(11):3047-3058.e4. doi: 10.1016/j.celrep.2018.11.043.


Syrosingopine sensitizes cancer cells to killing by metformin.

Benjamin D, Colombi M, Hindupur SK, Betz C, Lane HA, El-Shemerly MY, Lu M, Quagliata L, Terracciano L, Moes S, Sharpe T, Wodnar-Filipowicz A, Moroni C, Hall MN.

Sci Adv. 2016 Dec 23;2(12):e1601756. doi: 10.1126/sciadv.1601756. eCollection 2016 Dec.


Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase.

Urich M, el Shemerly MY, Besser D, Nagamine Y, Ballmer-Hofer K.

J Biol Chem. 1995 Dec 8;270(49):29286-92.

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