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Items: 1 to 50 of 868

1.

Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma.

Ho AS, Ochoa A, Jayakumaran G, Zehir A, Valero Mayor C, Tepe J, Makarov V, Dalin MG, He J, Bailey M, Montesion M, Ross JS, Miller VA, Chan L, Ganly I, Dogan S, Katabi N, Tsipouras P, Ha P, Agrawal N, Solit DB, Futreal PA, El Naggar AK, Reis-Filho JS, Weigelt B, Ho AL, Schultz N, Chan TA, Morris LG.

J Clin Invest. 2019 Oct 1;129(10):4276-4289. doi: 10.1172/JCI128227.

2.

Pan-Trk immunohistochemistry reliably identifies ETV6-NTRK3 fusion in secretory carcinoma of the salivary gland.

Bell D, Ferrarotto R, Liang L, Goepfert RP, Li J, Ning J, Broaddus R, Weber RS, El-Naggar AK.

Virchows Arch. 2019 Aug 19. doi: 10.1007/s00428-019-02640-7. [Epub ahead of print]

PMID:
31423558
3.
4.

Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors.

Amin LHT, Shawer TZ, El-Naggar AM, El-Sehrawi HMA.

Bioorg Chem. 2019 Oct;91:103159. doi: 10.1016/j.bioorg.2019.103159. Epub 2019 Jul 29.

PMID:
31382056
5.

Editor's Note: Epidermal Growth Factor Receptor (EGFR) Is Overexpressed in Anaplastic Thyroid Cancer, and the EGFR Inhibitor Gefitinib Inhibits the Growth of Anaplastic Thyroid Cancer.

Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN, Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN.

Clin Cancer Res. 2019 Aug 1;25(15):4862. doi: 10.1158/1078-0432.CCR-19-2052. No abstract available.

PMID:
31371312
6.

Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma.

Oh SH, Kim WY, Kim JH, Younes MN, El-Naggar AK, Myers JN, Kies M, Cohen P, Khuri F, Hong WK, Lee HY.

Clin Cancer Res. 2019 Aug 1;25(15):4861. doi: 10.1158/1078-0432.CCR-19-2054. No abstract available.

PMID:
31371311
7.

Ectopic ACTH Production and Cushing's Syndrome in a Patient with Parotid Acinic Cell Carcinoma with High-Grade Transformation: Tumor Context and Clinical Implications.

Saluja K, Ravishankar S, Ferrarotto R, Zhu H, Pytynia KB, El-Naggar AK.

Head Neck Pathol. 2019 Jul 30. doi: 10.1007/s12105-019-01054-w. [Epub ahead of print]

PMID:
31363907
8.

Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma.

Negri GL, Grande BM, Delaidelli A, El-Naggar A, Cochrane D, Lau CC, Triche TJ, Moore RA, Jones SJ, Montpetit A, Marra MA, Malkin D, Morin RD, Sorensen PH.

J Pathol. 2019 Nov;249(3):319-331. doi: 10.1002/path.5319. Epub 2019 Aug 28.

PMID:
31236944
9.

Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation.

Mazloomian A, Araki S, Ohori M, El-Naggar AM, Yap D, Bashashati A, Nakao S, Sorensen PH, Nakanishi A, Shah S, Aparicio S.

Commun Biol. 2019 May 3;2:165. doi: 10.1038/s42003-019-0391-9. eCollection 2019.

10.

Biochar composition-dependent impacts on soil nutrient release, carbon mineralization, and potential environmental risk: A review.

El-Naggar A, El-Naggar AH, Shaheen SM, Sarkar B, Chang SX, Tsang DCW, Rinklebe J, Ok YS.

J Environ Manage. 2019 Jul 1;241:458-467. doi: 10.1016/j.jenvman.2019.02.044. Epub 2019 Apr 24. Review.

PMID:
31027831
11.

Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination.

Aryal NK, Pant V, Wasylishen AR, Rimel BJ, Baseler L, El-Naggar AK, Mutch DG, Goodfellow PJ, Arur S, Lozano G.

Cancer Res. 2019 May 15;79(10):2662-2668. doi: 10.1158/0008-5472.CAN-18-2460. Epub 2019 Mar 26.

PMID:
30914430
12.

Is the cardioprotective effect of the ACE2 activator diminazene aceturate more potent than the ACE inhibitor enalapril on acute myocardial infarction in rats?

Badae NM, El Naggar AS, El Sayed SM.

Can J Physiol Pharmacol. 2019 Jul;97(7):638-646. doi: 10.1139/cjpp-2019-0078. Epub 2019 Mar 6.

PMID:
30840489
13.

Management of biosolids-derived hydrochar (Sewchar): Effect on plant germination, and farmers' acceptance.

Melo TM, Bottlinger M, Schulz E, Leandro WM, Botelho de Oliveira S, Menezes de Aguiar Filho A, El-Naggar A, Bolan N, Wang H, Ok YS, Rinklebe J.

J Environ Manage. 2019 May 1;237:200-214. doi: 10.1016/j.jenvman.2019.02.042. Epub 2019 Feb 21.

PMID:
30798039
14.

Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts.

Zidan A, El-Naggar AM, Abd El-Sattar NEA, Ali AK, El Kaïm L.

Front Chem. 2019 Jan 29;7:20. doi: 10.3389/fchem.2019.00020. eCollection 2019.

15.

Release dynamics of As, Co, and Mo in a biochar treated soil under pre-definite redox conditions.

El-Naggar A, Shaheen SM, Hseu ZY, Wang SL, Ok YS, Rinklebe J.

Sci Total Environ. 2019 Mar 20;657:686-695. doi: 10.1016/j.scitotenv.2018.12.026. Epub 2018 Dec 5.

PMID:
30677934
16.

GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland.

Nikiforova MN, Nikitski AV, Panebianco F, Kaya C, Yip L, Williams M, Chiosea SI, Seethala RR, Roy S, Condello V, Santana-Santos L, Wald AI, Carty SE, Ferris RL, El-Naggar AK, Nikiforov YE.

Thyroid. 2019 Feb;29(2):161-173. doi: 10.1089/thy.2018.0791.

PMID:
30648929
17.

The Role of Vildagliptin in Treating Hypertension Through Modulating Serum VEGF in Diabetic Hypertensive Patients.

El-Naggar AR, Zaafar D, Elyamany M, Hassanin S, Bassyouni A, Abdel-Latif H.

J Cardiovasc Pharmacol Ther. 2019 May;24(3):254-261. doi: 10.1177/1074248418817345. Epub 2019 Jan 10.

PMID:
30630371
18.

HACE1 is a potential tumor suppressor in osteosarcoma.

El-Naggar AM, Clarkson PW, Negri GL, Turgu B, Zhang F, Anglesio MS, Sorensen PH.

Cell Death Dis. 2019 Jan 8;10(1):21. doi: 10.1038/s41419-018-1276-4.

19.

Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo.

Aryal NK, Pant V, Wasylishen AR, Parker-Thornburg J, Baseler L, El-Naggar AK, Liu B, Kalia A, Lozano G, Arur S.

Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):960-969. doi: 10.1073/pnas.1814377116. Epub 2018 Dec 28.

20.

Dissolved organic matter characterization of biochars produced from different feedstock materials.

Rajapaksha AU, Ok YS, El-Naggar A, Kim H, Song F, Kang S, Tsang YF.

J Environ Manage. 2019 Mar 1;233:393-399. doi: 10.1016/j.jenvman.2018.12.069. Epub 2018 Dec 24.

PMID:
30590268
21.

PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.

Ibrahim MY, Nunez MI, Harun N, Lee JJ, El-Naggar AK, Ferrarotto R, Wistuba I, Myers J, Glisson BS, William WN Jr.

Head Neck. 2019 Mar;41(3):615-622. doi: 10.1002/hed.25350. Epub 2018 Dec 16.

PMID:
30556200
22.

Management of persistent juvenile angiofibroma after endoscopic resection: Analysis of a single institution series of 74 patients.

Schreiber A, Bertazzoni G, Ferrari M, Ravanelli M, Rampinelli V, Mattavelli D, El-Naggar A, Nicolai P.

Head Neck. 2019 May;41(5):1297-1303. doi: 10.1002/hed.25555. Epub 2018 Dec 10.

PMID:
30537195
23.

Effect of gasification biochar application on soil quality: Trace metal behavior, microbial community, and soil dissolved organic matter.

Yang X, Tsibart A, Nam H, Hur J, El-Naggar A, Tack FMG, Wang CH, Lee YH, Tsang DCW, Ok YS.

J Hazard Mater. 2019 Mar 5;365:684-694. doi: 10.1016/j.jhazmat.2018.11.042. Epub 2018 Nov 13.

PMID:
30472454
24.

Frequent PTEN loss and differential HER2/PI3K signaling pathway alterations in salivary duct carcinoma: Implications for targeted therapy.

Saintigny P, Mitani Y, Pytynia KB, Ferrarotto R, Roberts DB, Weber RS, Kies MS, Maity SN, Lin SH, El-Naggar AK.

Cancer. 2018 Sep 15;124(18):3693-3705. doi: 10.1002/cncr.31600. Epub 2018 Oct 5.

25.

Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.

Zhang Y, Xiong S, Liu B, Pant V, Celii F, Chau G, Elizondo-Fraire AC, Yang P, You MJ, El-Naggar AK, Navin NE, Lozano G.

Nat Commun. 2018 Sep 27;9(1):3953. doi: 10.1038/s41467-018-06146-9.

26.

Supero-medial reduction mammaplasty: a safe and reliable technique in gigantomastia and severe breast ptosis.

Ashour T, Khachaba Y, El Naggar A.

Electron Physician. 2018 Aug 25;10(8):7230-7234. doi: 10.19082/7230. eCollection 2018 Aug.

27.

A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal.

Rindi G, Klimstra DS, Abedi-Ardekani B, Asa SL, Bosman FT, Brambilla E, Busam KJ, de Krijger RR, Dietel M, El-Naggar AK, Fernandez-Cuesta L, Klöppel G, McCluggage WG, Moch H, Ohgaki H, Rakha EA, Reed NS, Rous BA, Sasano H, Scarpa A, Scoazec JY, Travis WD, Tallini G, Trouillas J, van Krieken JH, Cree IA.

Mod Pathol. 2018 Dec;31(12):1770-1786. doi: 10.1038/s41379-018-0110-y. Epub 2018 Aug 23.

28.

Novel Tetrahydrobenzo [b] Thiophene Compounds Exhibit Anticancer Activity through Enhancing Apoptosis and Inhibiting Tyrosine Kinase.

El-Metwally SA, Khalil AK, El-Naggar AM, El-Sayed WM.

Anticancer Agents Med Chem. 2018;18(12):1761-1769. doi: 10.2174/1871520618666180813120558.

PMID:
30101717
29.

Biochar affects the dissolved and colloidal concentrations of Cd, Cu, Ni, and Zn and their phytoavailability and potential mobility in a mining soil under dynamic redox-conditions.

El-Naggar A, Shaheen SM, Ok YS, Rinklebe J.

Sci Total Environ. 2018 May 15;624:1059-1071. doi: 10.1016/j.scitotenv.2017.12.190. Epub 2017 Dec 27.

PMID:
29929223
30.

Autoimmune Granulomatous Inflammation of Lacrimal Glands and Axonal Neuritis Following Treatment With Ipilimumab and Radiation Therapy.

Ileana Dumbrava E, Smith V, Alfattal R, El-Naggar AK, Penas-Prado M, Tsimberidou AM.

J Immunother. 2018 Sep;41(7):336-339. doi: 10.1097/CJI.0000000000000224.

31.

Novel Nicotinonitrile Derivatives Bearing Imino Moieties Enhance Apoptosis and Inhibit Tyrosine Kinase.

El-Hashash MA, El-Bordany EA, Marzouk MI, El-Naggar AM, Nawar TMS, El-Sayed WM.

Anticancer Agents Med Chem. 2018;18(11):1589-1598. doi: 10.2174/1871520618666180510112614.

PMID:
29745342
32.

Incompletely treated malignancies of the major salivary gland: Toward evidence-based care.

Tam S, Sandulache VC, Metwalli KA, Rock CD, Eraj SA, Sheu T, El-Naggar AK, Fuller CD, Weber RS, Lai SY.

Head Neck. 2018 Aug;40(8):1630-1638. doi: 10.1002/hed.25156. Epub 2018 May 7.

PMID:
29734482
33.

Structure and microanalysis of tear film ferning of camel tears, human tears, and Refresh Plus.

Am M, Ra F, El-Naggar AH, Tm A; Akhtar S.

Mol Vis. 2018 Apr 16;24:305-314. eCollection 2018.

34.

Possible Ameliorative Effect of Ivabradine on the Autonomic and Left Ventricular Dysfunction Induced by Doxorubicin in Male Rats.

El-Naggar AE, El-Gowilly SM, Sharabi FM.

J Cardiovasc Pharmacol. 2018 Jul;72(1):22-31. doi: 10.1097/FJC.0000000000000586.

PMID:
29688913
35.

Propargylation of Ugi Amide Dianion: An Entry into Pyrrolidinone and Benzoindolizidine Alkaloid Analogues.

Zidan A, Cordier M, El-Naggar AM, Abd El-Sattar NEA, Hassan MA, Ali AK, El Kaïm L.

Org Lett. 2018 May 4;20(9):2568-2571. doi: 10.1021/acs.orglett.8b00687. Epub 2018 Apr 23.

PMID:
29683331
36.

Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in thyroid tumor classification.

Kakudo K, El-Naggar AK, Hodak SP, Khanafshar E, Nikiforov YE, Nosé V, Thompson LDR.

Pathol Int. 2018 Jun;68(6):327-333. doi: 10.1111/pin.12673. Epub 2018 Apr 19. No abstract available.

PMID:
29675873
37.

Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer.

Saintigny P, William WN Jr, Foy JP, Papadimitrakopoulou V, Lang W, Zhang L, Fan YH, Feng L, Kim ES, El-Naggar AK, Lee JJ, Mao L, Hong WK, Lingen MW, Lippman SM.

J Natl Cancer Inst. 2018 Mar 1;110(3). doi: 10.1093/jnci/djx186.

38.

Three-dimensional imaging assessment of anatomic invasion and volumetric considerations for chemo/radiotherapy-based laryngeal preservation in T3 larynx cancer.

Kamal M, Ng SP, Eraj SA, Rock CD, Pham B, Messer JA, Garden AS, Morrison WH, Phan J, Frank SJ, El-Naggar AK, Johnson JM, Ginsberg LE, Ferrarotto R, Lewin JS, Hutcheson KA, Cardenas CE, Zafereo ME, Lai SY, Hessel AC, Weber RS, Gunn GB, Fuller CD, Mohamed ASR, Rosenthal DI.

Oral Oncol. 2018 Apr;79:1-8. doi: 10.1016/j.oraloncology.2018.01.025. Epub 2018 Feb 10.

39.

Transcriptomes define distinct subgroups of salivary gland adenoid cystic carcinoma with different driver mutations and outcomes.

Frerich CA, Brayer KJ, Painter BM, Kang H, Mitani Y, El-Naggar AK, Ness SA.

Oncotarget. 2017 Dec 23;9(7):7341-7358. doi: 10.18632/oncotarget.23641. eCollection 2018 Jan 26.

40.

Frequent and differential mutations of the CYLD gene in basal cell salivary neoplasms: linkage to tumor development and progression.

Rito M, Mitani Y, Bell D, Mariano FV, Almalki ST, Pytynia KB, Fonseca I, El-Naggar AK.

Mod Pathol. 2018 Jul;31(7):1064-1072. doi: 10.1038/s41379-018-0018-6. Epub 2018 Feb 20.

41.

World Health Organization 4th edition of head and neck tumor classification: insight into the consequential modifications.

Slootweg PJ, El-Naggar AK.

Virchows Arch. 2018 Mar;472(3):311-313. doi: 10.1007/s00428-018-2320-6. Epub 2018 Feb 15. No abstract available.

PMID:
29450648
42.

Synergistic and additive effect of retinoic acid in circumventing resistance to p53 restoration.

Larsson CA, Moyer SM, Liu B, Michel KA, Pant V, Yang P, Wong J, El-Naggar AK, Krahe R, Lozano G.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2198-2203. doi: 10.1073/pnas.1719001115. Epub 2018 Feb 13.

43.

A 60-year-old woman with an asymptomatic left lacrimal gland mass found incidentally.

Thakar SD, Sagiv O, Tetzlaff MT, El-Naggar A, Debnam JM, Kandl TJ, Esmaeli B.

Digit J Ophthalmol. 2017 Oct 18;23(4):27-29. doi: 10.5693/djo.03.2017.07.001. eCollection 2017. No abstract available.

44.

Translational control of aberrant stress responses as a hallmark of cancer.

El-Naggar AM, Sorensen PH.

J Pathol. 2018 Apr;244(5):650-666. doi: 10.1002/path.5030. Epub 2018 Feb 20. Review.

PMID:
29293271
45.

Malignant perivascular epithelioid cell tumor of the oropharynx with strong TFE3 expression mimicking alveolar soft part sarcoma: a case report and review of the literature.

Saluja K, Thomas J, Zhang S, Sturgis EM, Jain KS, Prieto VG, El-Naggar AK, Bell D.

Hum Pathol. 2018 Jun;76:149-155. doi: 10.1016/j.humpath.2017.11.016. Epub 2017 Dec 5. Review.

PMID:
29208563
46.

Spatio-Temporal Genomic Heterogeneity, Phylogeny, and Metastatic Evolution in Salivary Adenoid Cystic Carcinoma.

Liu B, Mitani Y, Rao X, Zafereo M, Zhang J, Zhang J, Futreal PA, Lozano G, El-Naggar AK.

J Natl Cancer Inst. 2017 Oct 1;109(10). doi: 10.1093/jnci/djx033.

47.

Blood Hematological and Biochemical Constituents, Antioxidant Enzymes, Immunity and Lymphoid Organs of Broiler Chicks Supplemented with Propolis, Bee Pollen and Mannan Oligosaccharides Continuously or Intermittently.

Attia YA, Al-Khalaifah H, Ibrahim MS, Al-Hamid AEA, Al-Harthi MA, El-Naggar A.

Poult Sci. 2017 Dec 1;96(12):4182-4192. doi: 10.3382/ps/pex173.

PMID:
29053876
48.

Potential of macroalgae for biodiesel production: Screening and evaluation studies.

Abomohra AE, El-Naggar AH, Baeshen AA.

J Biosci Bioeng. 2018 Feb;125(2):231-237. doi: 10.1016/j.jbiosc.2017.08.020. Epub 2017 Oct 13.

PMID:
29037768
49.

PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions.

Wang J, Xie T, Wang B, William WN Jr, Heymach JV, El-Naggar AK, Myers JN, Caulin C.

Cancer Prev Res (Phila). 2017 Dec;10(12):684-693. doi: 10.1158/1940-6207.CAPR-17-0108. Epub 2017 Oct 10.

50.

Brain derived neutrophic factor (BDNF) coordinates lympho-vascular metastasis through a fibroblast-governed paracrine axis in the tumor microenvironment.

Jiffar T, Yilmaz T, Lee J, Miller Y, Feng L, El-Naggar A, Kupferman ME.

Cancer Cell Microenviron. 2017;4(2). pii: e1566. doi: 10.14800/ccm.1566. Epub 2017 Jul 10.

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