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Items: 46

1.

Prognostic value of platelet and neutrophil to lymphocyte ratio in COPD patients.

El-Gazzar AG, Kamel MH, Elbahnasy OKM, El-Naggar ME.

Expert Rev Respir Med. 2019 Oct 13:1-6. doi: 10.1080/17476348.2019.1675517. [Epub ahead of print]

PMID:
31577911
2.

Carcinogenic effect of potassium octatitanate (POT) fibers in the lung and pleura of male Fischer 344 rats after intrapulmonary administration.

Abdelgied M, El-Gazzar AM, Alexander WT, Numano T, Iigou M, Naiki-Ito A, Takase H, Hirose A, Taquahashi Y, Kanno J, Abdelhamid M, Abdou KA, Takahashi S, Alexander DB, Tsuda H.

Part Fibre Toxicol. 2019 Sep 2;16(1):34. doi: 10.1186/s12989-019-0316-2.

3.

MWCNT-7 administered to the lung by intratracheal instillation induces development of pleural mesothelioma in F344 rats.

Numano T, Higuchi H, Alexander DB, Alexander WT, Abdelgied M, El-Gazzar AM, Saleh D, Takase H, Hirose A, Naiki-Ito A, Suzuki S, Takahashi S, Tsuda H.

Cancer Sci. 2019 Aug;110(8):2485-2492. doi: 10.1111/cas.14121. Epub 2019 Jul 25.

4.

Health care providers' perceptions and practices of screening for domestic violence in Upper Egypt.

Aziz MM, El-Gazzar AF.

Sex Reprod Healthc. 2019 Jun;20:93-99. doi: 10.1016/j.srhc.2019.04.003. Epub 2019 Apr 4.

PMID:
31084827
5.

Pulmonary and pleural toxicity of potassium octatitanate fibers, rutile titanium dioxide nanoparticles, and MWCNT-7 in male Fischer 344 rats.

Abdelgied M, El-Gazzar AM, Alexander DB, Alexander WT, Numano T, Iigou M, Naiki-Ito A, Takase H, Abdou KA, Hirose A, Taquahashi Y, Kanno J, Abdelhamid M, Tsuda H, Takahashi S.

Arch Toxicol. 2019 Apr;93(4):909-920. doi: 10.1007/s00204-019-02410-z. Epub 2019 Feb 13.

PMID:
30759267
6.

Comparative pulmonary toxicity of a DWCNT and MWCNT-7 in rats.

El-Gazzar AM, Abdelgied M, Alexander DB, Alexander WT, Numano T, Iigo M, Naiki A, Takahashi S, Takase H, Hirose A, Kannno J, Elokle OS, Nazem AM, Tsuda H.

Arch Toxicol. 2019 Jan;93(1):49-59. doi: 10.1007/s00204-018-2336-3. Epub 2018 Oct 19.

7.

Persistent Pleural Lesions and Inflammation by Pulmonary Exposure of Multiwalled Carbon Nanotubes.

Liao D, Wang Q, He J, Alexander DB, Abdelgied M, El-Gazzar AM, Futakuchi M, Suzui M, Kanno J, Hirose A, Xu J, Tsuda H.

Chem Res Toxicol. 2018 Oct 15;31(10):1025-1031. doi: 10.1021/acs.chemrestox.8b00067. Epub 2018 Sep 13.

PMID:
30212183
8.

Factors associated with first-year discontinuation of Implanon in Upper Egypt: clients' and providers' perspectives.

Aziz MM, El-Gazzar AF, Elgibaly O.

BMJ Sex Reprod Health. 2018 Jun 28. pii: jfprhc-2017-101860. doi: 10.1136/bmjsrh-2017-101860. [Epub ahead of print]

PMID:
29954878
9.

Potassium octatitanate fibers induce persistent lung and pleural injury and are possibly carcinogenic in male Fischer 344 rats.

Abdelgied M, El-Gazzar AM, Alexander DB, Alexander WT, Numano T, Iigou M, Naiki-Ito A, Takase H, Abdou KA, Hirose A, Taquahashi Y, Kanno J, Tsuda H, Takahashi S.

Cancer Sci. 2018 Jul;109(7):2164-2177. doi: 10.1111/cas.13643. Epub 2018 Jun 22.

10.

2-Amino-3-methylcarboxy-5-heptyl-thiophene (TJ191) is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.

El-Gazzar A, Noppen S, Thomas J, Dehaen W, Balzarini J, Liekens S.

Oncotarget. 2017 Dec 15;9(5):6259-6269. doi: 10.18632/oncotarget.23501. eCollection 2018 Jan 19.

11.

Synthesis and evaluation of antitumor activity of new 4-substituted thieno[3,2-d]pyrimidine and thienotriazolopyrimidine derivatives.

Hafez HN, El-Gazzar ABA.

Acta Pharm. 2017 Dec 20;67(4):527-542. doi: 10.1515/acph-2017-0039.

PMID:
29337675
12.

Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents.

Hafez HN, Alsalamah SA, El-Gazzar ABA.

Acta Pharm. 2017 Sep 1;67(3):275-292. doi: 10.1515/acph-2017-0028.

PMID:
28858838
13.

Maternal mortality in an academic institution in Upper Egypt.

Zahran KM, Fadel KA, Ahmed SM, El-Gazzar AF.

J Obstet Gynaecol. 2017 Apr;37(3):315-319. doi: 10.1080/01443615.2016.1242559. Epub 2016 Dec 14.

PMID:
27960569
14.
15.
16.

Mobile clinics for women's and children's health.

Abdel-Aleem H, El-Gibaly OM, El-Gazzar AF, Al-Attar GS.

Cochrane Database Syst Rev. 2016 Aug 11;(8):CD009677. doi: 10.1002/14651858.CD009677.pub2. Review.

PMID:
27513824
17.

Simple approach to thieno[3,2-d]pyrimidines as new scaffolds of antimicrobial activities.

Hafez HN, El-Gazzar AR, Zaki ME.

Acta Pharm. 2016 Sep 1;66(3):331-51. doi: 10.1515/acph-2016-0029.

PMID:
27383884
18.

Novel pyrazole derivatives with oxa/thiadiazolyl, pyrazolyl moieties and pyrazolo[4,3-d]-pyrimidine derivatives as potential antimicrobial and anticancer agents.

Hafez HN, El-Gazzar ABA, Al-Hussain SA.

Bioorg Med Chem Lett. 2016 May 15;26(10):2428-2433. doi: 10.1016/j.bmcl.2016.03.117. Epub 2016 Apr 2.

PMID:
27080187
19.

Facile heterocyclic synthesis and antimicrobial activity of polysubstituted and condensed pyrazolopyranopyrimidine and pyrazolopyranotriazine derivatives.

Hafez HN, Alshammari AG, El-Gazzar AR.

Acta Pharm. 2015 Dec;65(4):399-412. doi: 10.1515/acph-2015-0037.

PMID:
26677897
20.
21.

Vitamin C modulates cadmium-induced hepatic antioxidants' gene transcripts and toxicopathic changes in Nile tilapia, Oreochromis niloticus.

El-Sayed YS, El-Gazzar AM, El-Nahas AF, Ashry KM.

Environ Sci Pollut Res Int. 2016 Jan;23(2):1664-70. doi: 10.1007/s11356-015-5412-8. Epub 2015 Sep 18.

PMID:
26385855
22.

HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells.

Marhold M, Tomasich E, El-Gazzar A, Heller G, Spittler A, Horvat R, Krainer M, Horak P.

Mol Cancer Res. 2015 Mar;13(3):556-64. doi: 10.1158/1541-7786.MCR-14-0153-T. Epub 2014 Oct 27.

23.

The potential evasion of immune surveillance in mucosa associated lymphoid tissue lymphoma by DcR2-mediated up-regulation of nuclear factor-κB.

Anees M, Horak P, Schiefer AI, Vaňhara P, El-Gazzar A, Perco P, Kiesewetter B, Müllauer L, Streubel B, Raderer M, Krainer M.

Leuk Lymphoma. 2015 May;56(5):1440-9. doi: 10.3109/10428194.2014.953149. Epub 2014 Nov 5.

PMID:
25248880
24.

Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells.

El-Gazzar A, Cai X, Reeves RS, Dai Z, Caballero-Benitez A, McDonald DL, Vazquez J, Gooley TA, Sale GE, Spies T, Groh V.

Oncogene. 2014 Oct 9;33(41):4932-40. doi: 10.1038/onc.2013.435. Epub 2013 Oct 21.

25.

Immunobiology and conflicting roles of the human NKG2D lymphocyte receptor and its ligands in cancer.

El-Gazzar A, Groh V, Spies T.

J Immunol. 2013 Aug 15;191(4):1509-15. doi: 10.4049/jimmunol.1301071. Review.

26.

hVps37A Status affects prognosis and cetuximab sensitivity in ovarian cancer.

Wittinger M, Vanhara P, El-Gazzar A, Savarese-Brenner B, Pils D, Anees M, Grunt TW, Sibilia M, Holcmann M, Horvat R, Schemper M, Zeillinger R, Schöfer C, Dolznig H, Horak P, Krainer M.

Clin Cancer Res. 2011 Dec 15;17(24):7816-27. doi: 10.1158/1078-0432.CCR-11-0408. Epub 2011 Oct 20.

27.

Recurrence-free survival in prostate cancer is related to increased stromal TRAIL expression.

Anees M, Horak P, El-Gazzar A, Susani M, Heinze G, Perco P, Loda M, Lis R, Krainer M, Oh WK.

Cancer. 2011 Mar 15;117(6):1172-82. doi: 10.1002/cncr.25504. Epub 2010 Nov 8.

28.

Synthesis, in vitro antimicrobial and in vivo antitumor evaluation of novel pyrimidoquinolines and its nucleoside derivatives.

Abbas HA, Hafez HN, El-Gazzar AR.

Eur J Med Chem. 2011 Jan;46(1):21-30. doi: 10.1016/j.ejmech.2010.09.071. Epub 2010 Oct 8.

PMID:
21074295
29.

Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents.

Hafez HN, Hussein HA, El-Gazzar AR.

Eur J Med Chem. 2010 Sep;45(9):4026-34. doi: 10.1016/j.ejmech.2010.05.060. Epub 2010 Jun 2.

PMID:
20691339
30.

Natural immunity enhances the activity of a DR5 agonistic antibody and carboplatin in the treatment of ovarian cancer.

El-Gazzar A, Perco P, Eckelhart E, Anees M, Sexl V, Mayer B, Liu Y, Mikulits W, Horvat R, Pangerl T, Zheng D, Krainer M.

Mol Cancer Ther. 2010 Apr;9(4):1007-18. doi: 10.1158/1535-7163.MCT-09-0933. Epub 2010 Apr 6.

31.

The role of c-FLIP(L) in ovarian cancer: chaperoning tumor cells from immunosurveillance and increasing their invasive potential.

El-Gazzar A, Wittinger M, Perco P, Anees M, Horvat R, Mikulits W, Grunt TW, Mayer B, Krainer M.

Gynecol Oncol. 2010 Jun;117(3):451-9. doi: 10.1016/j.ygyno.2010.02.024. Epub 2010 Mar 15.

PMID:
20227749
32.

Synthesis, biological and medicinal significance of S-glycosido-thieno[2,3-d]-pyrimidines as new anti-inflammatory and analgesic agents.

Hafez HN, El-Gazzar AR, Nawwar GA.

Eur J Med Chem. 2010 Apr;45(4):1485-93. doi: 10.1016/j.ejmech.2009.12.056. Epub 2010 Jan 13.

PMID:
20116903
33.

S- and C-nucleosidoquinazoline as new nucleoside analogs with potential analgesic and anti-inflammatory activity.

El-Gazzar AR, Hafez HN, Abbas HA.

Eur J Med Chem. 2009 Oct;44(10):4249-58. doi: 10.1016/j.ejmech.2009.05.025. Epub 2009 May 28.

PMID:
19541393
34.

Synthesis and antitumor activity of substituted triazolo[4,3-a]pyrimidin-6-sulfonamide with an incorporated thiazolidinone moiety.

Hafez HN, El-Gazzar AR.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4143-7. doi: 10.1016/j.bmcl.2009.05.126. Epub 2009 Jun 6.

PMID:
19540114
35.

Synthesis of 4-substituted pyrido[2,3-d]pyrimidin-4(1H)-one as analgesic and anti-inflammatory agents.

El-Gazzar AR, Hafez HN.

Bioorg Med Chem Lett. 2009 Jul 1;19(13):3392-7. doi: 10.1016/j.bmcl.2009.05.044. Epub 2009 May 18.

PMID:
19481936
36.

Synthesis and evaluation of analgesic, anti-inflammatory and ulcerogenic activities of some triazolo- and 2-pyrazolyl-pyrido[2,3-d]-pyrimidines.

Hafez HN, Abbas HA, El-Gazzar AR.

Acta Pharm. 2008 Dec;58(4):359-78. doi: 10.2478/v10007-008-0024-1.

PMID:
19103572
37.

New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines.

el-Gazzar AB, Hafez HN, Nawwar GA.

Eur J Med Chem. 2009 Apr;44(4):1427-36. doi: 10.1016/j.ejmech.2008.09.030. Epub 2008 Oct 2.

PMID:
18977557
38.

Design and synthesis of 3-pyrazolyl-thiophene, thieno[2,3-d]pyrimidines as new bioactive and pharmacological activities.

Hafez HN, El-Gazzar AB.

Bioorg Med Chem Lett. 2008 Oct 1;18(19):5222-7. doi: 10.1016/j.bmcl.2008.08.071. Epub 2008 Aug 26.

PMID:
18783947
39.

A facile regioselective synthesis of novel spiro-thioxanthene and spiro-xanthene-9',2-[1,3,4]thiadiazole derivatives as potential analgesic and anti-inflammatory agents.

Hafez HN, Hegab MI, Ahmed-Farag IS, el-Gazzar AB.

Bioorg Med Chem Lett. 2008 Aug 15;18(16):4538-43. doi: 10.1016/j.bmcl.2008.07.042. Epub 2008 Jul 15.

PMID:
18667305
40.

Design and synthesis of azolopyrimidoquinolines, pyrimidoquinazolines as anti-oxidant, anti-inflammatory and analgesic activities.

El-Gazzar AB, Youssef MM, Youssef AM, Abu-Hashem AA, Badria FA.

Eur J Med Chem. 2009 Feb;44(2):609-24. doi: 10.1016/j.ejmech.2008.03.022. Epub 2008 Apr 8.

PMID:
18462840
41.

Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.

El-Gazzar AR, Hussein HA, Hafez HN.

Acta Pharm. 2007 Dec;57(4):395-411. doi: 10.2478/v10007-007-0032-6.

PMID:
18165185
42.

Synthesis, analgesic, anti-inflammatory, and antimicrobial activity of some novel pyrimido[4,5-b]quinolin-4-ones.

El-Gazzar AR, El-Enany MM, Mahmoud MN.

Bioorg Med Chem. 2008 Mar 15;16(6):3261-73. Epub 2007 Dec 14.

PMID:
18158248
43.

Investigative study of radiopharmaceuticals useful for imaging skeletal muscle injury in experimental animals.

Owunwanne A, Malki A, Sadek S, el-Gazzar A, Yacoub T, Abdel-Dayem HM.

Am J Physiol Imaging. 1989;4(2):62-5.

PMID:
2547406
44.

Experience with thallium-201 imaging in head and neck cancer.

el-Gazzar AH, Sahweil A, Abdel-Dayem HM, Kubasik H, Halker R, Hassan IM, Jamil M, Rageb A, Abdul-Rahim SM, Mahmoud A, et al.

Clin Nucl Med. 1988 Apr;13(4):286-90.

PMID:
3370896
45.

Hydatid disease in Kuwait.

EL GAZZAR A, McCREADIE DW.

Br Med J. 1962 Jul 28;2(5299):232-4. No abstract available.

46.

Pilonidal sinus and cyst. A new method of primary suture.

EL-GAZZAR A.

J Egypt Med Assoc. 1960;43:66-9. No abstract available.

PMID:
13696688

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