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Human host defence peptide LL37 and anti-cyclic citrullinated peptide antibody in early inflammatory arthritis.

Hitchon CA, Meng X, El Gabalawy HS, Larcombe L.

RMD Open. 2019 Apr 29;5(1):e000874. doi: 10.1136/rmdopen-2018-000874. eCollection 2019.


N-Linked Glycans in the Variable Domain of IgG Anti-Citrullinated Protein Antibodies Predict the Development of Rheumatoid Arthritis.

Hafkenscheid L, de Moel E, Smolik I, Tanner S, Meng X, Jansen BC, Bondt A, Wuhrer M, Huizinga TWJ, Toes REM, El-Gabalawy H, Scherer HU.

Arthritis Rheumatol. 2019 May 8. doi: 10.1002/art.40920. [Epub ahead of print]


A Prospective Study of the Development of Inflammatory Arthritis in the Family Members of Indigenous North American People With Rheumatoid Arthritis.

Tanner S, Dufault B, Smolik I, Meng X, Anaparti V, Hitchon C, Robinson DB, Robinson W, Sokolove J, Lahey L, Ferucci ED, El-Gabalawy H.

Arthritis Rheumatol. 2019 Sep;71(9):1494-1503. doi: 10.1002/art.40880. Epub 2019 Aug 1.


A comparative study of the gut microbiota in immune-mediated inflammatory diseases-does a common dysbiosis exist?

Forbes JD, Chen CY, Knox NC, Marrie RA, El-Gabalawy H, de Kievit T, Alfa M, Bernstein CN, Van Domselaar G.

Microbiome. 2018 Dec 13;6(1):221. doi: 10.1186/s40168-018-0603-4.


Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects.

Anaparti V, Smolik I, Meng X, Spicer V, Mookherjee N, El-Gabalawy H.

Arthritis Res Ther. 2017 Nov 10;19(1):249. doi: 10.1186/s13075-017-1459-x.


The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease.

Amir Shaghaghi M, Zhouyao H, Tu H, El-Gabalawy H, Crow GH, Levine M, Bernstein CN, Eck P.

Am J Clin Nutr. 2017 Dec;106(6):1508-1513. doi: 10.3945/ajcn.116.147603. Epub 2017 Sep 27.


Impact of risk factors associated with cardiovascular outcomes in patients with rheumatoid arthritis.

Crowson CS, Rollefstad S, Ikdahl E, Kitas GD, van Riel PLCM, Gabriel SE, Matteson EL, Kvien TK, Douglas K, Sandoo A, Arts E, Wållberg-Jonsson S, Innala L, Karpouzas G, Dessein PH, Tsang L, El-Gabalawy H, Hitchon C, Ramos VP, Yáñez IC, Sfikakis PP, Zampeli E, Gonzalez-Gay MA, Corrales A, Laar MV, Vonkeman HE, Meek I, Semb AG; A Trans-Atlantic Cardiovascular Consortium for Rheumatoid Arthritis (ATACC-RA).

Ann Rheum Dis. 2018 Jan;77(1):48-54. doi: 10.1136/annrheumdis-2017-211735. Epub 2017 Sep 6.


Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

Scally SW, Law SC, Ting YT, Heemst JV, Sokolove J, Deutsch AJ, Bridie Clemens E, Moustakas AK, Papadopoulos GK, van der Woude D, Smolik I, Hitchon CA, Robinson DB, Ferucci ED, Bernstein CN, Meng X, Anaparti V, Huizinga T, Kedzierska K, Reid HH, Raychaudhuri S, Toes RE, Rossjohn J, El-Gabalawy H, Thomas R.

Ann Rheum Dis. 2017 Nov;76(11):1915-1923. doi: 10.1136/annrheumdis-2017-211300. Epub 2017 Aug 11.


Effect of chitosan and coagulation factors on the wound repair phenotype of bioengineered blood clots.

Hoemann CD, Marchand C, Rivard GE, El-Gabalawy H, Poubelle PE.

Int J Biol Macromol. 2017 Nov;104(Pt B):1916-1924. doi: 10.1016/j.ijbiomac.2017.04.114. Epub 2017 May 13.


Characterization of Autoantigens Targeted by Anti-Citrullinated Protein Antibodies In Vivo: Prominent Role for Epitopes Derived from Histone 4 Proteins.

Meng X, Ezzati P, Smolik I, Bernstein CN, Hitchon CA, El-Gabalawy HS.

PLoS One. 2016 Oct 27;11(10):e0165501. doi: 10.1371/journal.pone.0165501. eCollection 2016.



Hitchon CA, Koppejan H, Trouw LA, Huizinga TJ, Toes RE, El-Gabalawy HS.

Arthritis Rheumatol. 2016 Nov;68(11):2826-2827. doi: 10.1002/art.39831. Epub 2016 Oct 9. No abstract available.


Genre, travail et vieillissement.

Tannenbaum C, Voss P, El-Gabalawy H, Joanette Y.

Can J Aging. 2016 Sep;35(3):412-9. doi: 10.1017/S0714980816000428. Epub 2016 Aug 1. No abstract available.


Gender, Work, and Aging.

Tannenbaum C, Voss P, El-Gabalawy H, Joanette Y.

Can J Aging. 2016 Sep;35(3):405-11. doi: 10.1017/S0714980816000416. Epub 2016 Jul 15. No abstract available.


Inflammatory Arthritis Prevalence and Health Services Use in the First Nations and Non-First Nations Populations of Alberta, Canada.

Barnabe C, Jones CA, Bernatsky S, Peschken CA, Voaklander D, Homik J, Crowshoe LF, Esdaile JM, El-Gabalawy H, Hemmelgarn B.

Arthritis Care Res (Hoboken). 2017 Apr;69(4):467-474. doi: 10.1002/acr.22959. Epub 2017 Mar 9.


Role of Anti-Carbamylated Protein Antibodies Compared to Anti-Citrullinated Protein Antibodies in Indigenous North Americans With Rheumatoid Arthritis, Their First-Degree Relatives, and Healthy Controls.

Koppejan H, Trouw LA, Sokolove J, Lahey LJ, Huizinga TJ, Smolik IA, Robinson DB, El-Gabalawy HS, Toes RE, Hitchon CA.

Arthritis Rheumatol. 2016 Sep;68(9):2090-8. doi: 10.1002/art.39664.


Effects of Rituximab and Infliximab Treatment on Carboxypeptidase B and Its Substrates in RA Synovium.

Edginton S, Hitchon C, Froese W, El-Gabalawy H.

J Rheumatol. 2016 May;43(5):846-54. doi: 10.3899/jrheum.150869. Epub 2016 Mar 1.


Development of an SRM method for absolute quantitation of MYDGF/C19orf10 protein.

Dwivedi RC, Krokhin OV, El-Gabalawy HS, Wilkins JA.

Proteomics Clin Appl. 2016 Jun;10(6):663-70. doi: 10.1002/prca.201500057. Epub 2015 Dec 15.


Protracted superficial granulomatosis with polyangiitis: a therapeutic challenge.

O'Neil L, Robinson D, Hamza S, El-Gabalawy H.

J Clin Rheumatol. 2015 Jan;21(1):49-51. doi: 10.1097/RHU.0000000000000206. No abstract available.


A computational method to differentiate normal individuals, osteoarthritis and rheumatoid arthritis patients using serum biomarkers.

Heard BJ, Rosvold JM, Fritzler MJ, El-Gabalawy H, Wiley JP, Krawetz RJ.

J R Soc Interface. 2014 Aug 6;11(97):20140428. doi: 10.1098/rsif.2014.0428.


Enhancement of Rituximab-induced cell death by the physical association of CD20 with CD40 molecules on the cell surface.

Al-Zoobi L, Salti S, Colavecchio A, Jundi M, Nadiri A, Hassan GS, El-Gabalawy H, Mourad W.

Int Immunol. 2014 Aug;26(8):451-65. doi: 10.1093/intimm/dxu046. Epub 2014 May 15.


Single-nucleotide polymorphisms in SLC22A23 are associated with ulcerative colitis in a Canadian white cohort.

Serrano León A, Amir Shaghaghi M, Yurkova N, Bernstein CN, El-Gabalawy H, Eck P.

Am J Clin Nutr. 2014 Jul;100(1):289-94. doi: 10.3945/ajcn.113.080549. Epub 2014 Apr 16.


Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE.

Deane KD, El-Gabalawy H.

Nat Rev Rheumatol. 2014 Apr;10(4):212-28. doi: 10.1038/nrrheum.2014.6. Epub 2014 Feb 11. Review.


Polymorphisms in the sodium-dependent ascorbate transporter gene SLC23A1 are associated with susceptibility to Crohn disease.

Amir Shaghaghi M, Bernstein CN, Serrano León A, El-Gabalawy H, Eck P.

Am J Clin Nutr. 2014 Feb;99(2):378-83. doi: 10.3945/ajcn.113.068015. Epub 2013 Nov 27.


High degree of correlation between whole blood and PBMC expression levels of miR-155 and miR-146a in healthy controls and rheumatoid arthritis patients.

Mookherjee N, El-Gabalawy HS.

J Immunol Methods. 2013 Dec 31;400-401:106-10. doi: 10.1016/j.jim.2013.10.001. Epub 2013 Oct 11.


Prevalence of anti-peptidylarginine deiminase type 4 antibodies in rheumatoid arthritis and unaffected first-degree relatives in indigenous North American Populations.

Ferucci ED, Darrah E, Smolik I, Choromanski TL, Robinson DB, Newkirk MM, Fritzler MJ, Rosen A, El-Gabalawy HS.

J Rheumatol. 2013 Sep;40(9):1523-8. doi: 10.3899/jrheum.130293. Epub 2013 Aug 1.


Intraarticular and systemic inflammatory profiles may identify patients with osteoarthritis.

Heard BJ, Fritzler MJ, Wiley JP, McAllister J, Martin L, El-Gabalawy H, Hart DA, Frank CB, Krawetz R.

J Rheumatol. 2013 Aug;40(8):1379-87. doi: 10.3899/jrheum.121204. Epub 2013 May 15.


First-degree relatives of patients with rheumatoid arthritis exhibit high prevalence of joint symptoms.

Smolik I, Robinson DB, Bernstein CN, El-Gabalawy HS.

J Rheumatol. 2013 Jun;40(6):818-24. doi: 10.3899/jrheum.121016. Epub 2013 Mar 15.


Cancer risk in systemic lupus: an updated international multi-centre cohort study.

Bernatsky S, Ramsey-Goldman R, Labrecque J, Joseph L, Boivin JF, Petri M, Zoma A, Manzi S, Urowitz MB, Gladman D, Fortin PR, Ginzler E, Yelin E, Bae SC, Wallace DJ, Edworthy S, Jacobsen S, Gordon C, Dooley MA, Peschken CA, Hanly JG, Alarcón GS, Nived O, Ruiz-Irastorza G, Isenberg D, Rahman A, Witte T, Aranow C, Kamen DL, Steinsson K, Askanase A, Barr S, Criswell LA, Sturfelt G, Patel NM, Senécal JL, Zummer M, Pope JE, Ensworth S, El-Gabalawy H, McCarthy T, Dreyer L, Sibley J, St Pierre Y, Clarke AE.

J Autoimmun. 2013 May;42:130-5. doi: 10.1016/j.jaut.2012.12.009. Epub 2013 Feb 12.


Pregnancy and the risk of rheumatoid arthritis in a highly predisposed North American Native population.

Peschken CA, Robinson DB, Hitchon CA, Smolik I, Hart D, Bernstein CN, El-Gabalawy HS.

J Rheumatol. 2012 Dec;39(12):2253-60. doi: 10.3899/jrheum.120269. Epub 2012 Oct 15.


Kinematic Analysis of Gait Following Intra-articular Corticosteroid Injection into the Knee Joint with an Acute Exacerbation of Arthritis.

Mehta S, Shay BL, Szturm T, El-Gabalawy HS.

Physiother Can. 2011 Fall;63(4):395-404. doi: 10.3138/ptc.2010-26. Epub 2011 Oct 20.


Vitamin D receptor polymorphism rs2228570 (Fok1) is associated with rheumatoid arthritis in North American natives.

Hitchon CA, Sun Y, Robinson DB, Peschken CA, Bernstein CN, Siminovitch KA, El-Gabalawy HS.

J Rheumatol. 2012 Sep;39(9):1792-7. doi: 10.3899/jrheum.120387. Epub 2012 Aug 1.


Evaluating systemic lupus erythematosus patients for lung involvement.

Allen D, Fischer A, Bshouty Z, Robinson DB, Peschken CA, Hitchon C, El-Gabalawy H, Meyers M, Mittoo S.

Lupus. 2012 Oct;21(12):1316-25. Epub 2012 Jul 19.


Chronic smoke exposure induces rheumatoid factor and anti-heat shock protein 70 autoantibodies in susceptible mice and humans with lung disease.

Newkirk MM, Mitchell S, Procino M, Li Z, Cosio M, Mazur W, Kinnula VL, Hudson M, Baron M, Fritzler MJ, El-Gabalawy HS.

Eur J Immunol. 2012 Apr;42(4):1051-61. doi: 10.1002/eji.201141856.


Prevalence of genetic variants associated with inflammatory bowel disease in a healthy First Nations cohort.

Murdoch TB, Bernstein CN, El-Gabalawy H, Stempak JM, Sargent M, Elias B, Xu W, Pathan S, Silverberg MS.

CMAJ. 2012 May 15;184(8):E435-41. doi: 10.1503/cmaj.110613. Epub 2012 Apr 10. Erratum in: CMAJ. 2012 Jul 10;184(10):1176.


Oral health in a First Nations and a non-Aboriginal population in Manitoba.

Blanchard AK, Wang X, El-Gabalawy H, Tan Q, Orr P, Elias B, Rawsthorne P, Hart D, Chubey S, Bernstein CN.

Int J Circumpolar Health. 2012 Mar 19;71:17394. doi: 10.3402/ijch.v71i0.17394.


Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients.

El-Gabalawy HS, Robinson DB, Smolik I, Hart D, Elias B, Wong K, Peschken CA, Hitchon CA, Li X, Bernstein CN, Newkirk MM, Fritzler MJ.

Arthritis Rheum. 2012 Jun;64(6):1720-9. doi: 10.1002/art.34449. Epub 2012 Feb 21.


The synovium in rheumatoid arthritis.

Hitchon CA, El-Gabalawy HS.

Open Rheumatol J. 2011;5:107-14. doi: 10.2174/1874312901105010107. Epub 2011 Dec 30.


Enrichment of variations in KIR3DL1/S1 and KIR2DL2/L3 among H1N1/09 ICU patients: an exploratory study.

La D, Czarnecki C, El-Gabalawy H, Kumar A, Meyers AF, Bastien N, Simonsen JN, Plummer FA, Luo M.

PLoS One. 2011;6(12):e29200. doi: 10.1371/journal.pone.0029200. Epub 2011 Dec 28.


Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis.

Suwannalai P, van de Stadt LA, Radner H, Steiner G, El-Gabalawy HS, Zijde CM, van Tol MJ, van Schaardenburg D, Huizinga TW, Toes RE, Trouw LA.

Arthritis Rheum. 2012 May;64(5):1323-8. doi: 10.1002/art.33489.


If at first you don't succeed: try, try again.

Saeed M, Rubinger M, Ahsanuddin A, Morales C, Penner B, Robinson D, El-Gabalawy H, Zarychanski R.

Am J Hematol. 2012 Mar;87(3):295-7. doi: 10.1002/ajh.22236. Epub 2011 Nov 16. No abstract available.


The role of inflammation in the pathophysiology of depression: different treatments and their effects.

Lotrich FE, El-Gabalawy H, Guenther LC, Ware CF.

J Rheumatol Suppl. 2011 Nov;88:48-54. doi: 10.3899/jrheum.110903. Review.


The influence of uveitis on patients with immune-mediated inflammatory disease.

Rosenbaum JT, Russell AS, Guenther LC, El-Gabalawy H.

J Rheumatol Suppl. 2011 Nov;88:26-30. doi: 10.3899/jrheum.110907. Review.


Defining the mechanism of action of herbal therapies in rheumatoid arthritis: is this the road to clinical development and acceptance?

Mookherjee N, El-Gabalawy H.

J Rheumatol. 2011 Sep;38(9):1817-9. doi: 10.3899/jrheum.110823. No abstract available.


Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts.

Turner-Brannen E, Choi KY, Lippert DN, Cortens JP, Hancock RE, El-Gabalawy H, Mookherjee N.

Arthritis Res Ther. 2011 Aug 11;13(4):R129. doi: 10.1186/ar3440.


Assessing inflammatory bowel disease-associated antibodies in Caucasian and First Nations cohorts.

Bernstein CN, El-Gabalawy H, Sargent M, Landers C, Rawsthorne P, Elias B, Targan SR.

Can J Gastroenterol. 2011 May;25(5):269-73.


Non-HLA genes modulate the risk of rheumatoid arthritis associated with HLA-DRB1 in a susceptible North American Native population.

El-Gabalawy HS, Robinson DB, Daha NA, Oen KG, Smolik I, Elias B, Hart D, Bernstein CN, Sun Y, Lu Y, Houwing-Duistermaat JJ, Siminovitch KA.

Genes Immun. 2011 Oct;12(7):568-74. doi: 10.1038/gene.2011.30. Epub 2011 May 26.


Inflammatory cytokines IL-32 and IL-17 have common signaling intermediates despite differential dependence on TNF-receptor 1.

Turner-Brannen E, Choi KY, Arsenault R, El-Gabalawy H, Napper S, Mookherjee N.

J Immunol. 2011 Jun 15;186(12):7127-35. doi: 10.4049/jimmunol.1002306. Epub 2011 May 20.


Infection and rheumatoid arthritis: still an open question.

Hitchon CA, El-Gabalawy HS.

Curr Opin Rheumatol. 2011 Jul;23(4):352-7. doi: 10.1097/BOR.0b013e3283477b7b. Review.


Pathophysiology and pathogenesis of immune-mediated inflammatory diseases: commonalities and differences.

Rahman P, Inman RD, El-Gabalawy H, Krause DO.

J Rheumatol Suppl. 2010 May;85:11-26. doi: 10.3899/jrheum.091462. Review.


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