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Items: 1 to 50 of 102

1.

Estrogen determines sex differences in adrenergic vessel tone by regulation of endothelial β-adrenoceptor expression.

Riedel K, Deussen AJ, Tolkmitt J, Weber S, Schlinkert P, Zatschler B, Friebel C, Müller B, El-Armouche A, Morawietz H, Matschke K, Kopaliani I.

Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H243-H254. doi: 10.1152/ajpheart.00456.2018. Epub 2019 May 31.

PMID:
31149843
2.

Electrophysiological Properties of Adult Zebrafish Oligodendrocyte Progenitor Cells.

Tsata V, Kroehne V, Reinhardt S, El-Armouche A, Brand M, Wagner M, Reimer MM.

Front Cell Neurosci. 2019 Apr 12;13:102. doi: 10.3389/fncel.2019.00102. eCollection 2019.

3.

Protein kinase/phosphatase balance mediates the effects of increased late sodium current on ventricular calcium cycling.

Eiringhaus J, Herting J, Schatter F, Nikolaev VO, Sprenger J, Wang Y, Köhn M, Zabel M, El-Armouche A, Hasenfuss G, Sossalla S, Fischer TH.

Basic Res Cardiol. 2019 Feb 20;114(2):13. doi: 10.1007/s00395-019-0720-7.

PMID:
30788598
4.

DPP10 is a new regulator of Nav1.5 channels in human heart.

Belau F, Metzner K, Christ T, Ravens U, Schaefer M, Künzel S, Li W, Wettwer E, Dobrev D, El-Armouche A, Kämmerer S.

Int J Cardiol. 2019 Jun 1;284:68-73. doi: 10.1016/j.ijcard.2018.12.072. Epub 2019 Jan 3.

PMID:
30638748
5.

The reduced activity of PP-1α under redox stress condition is a consequence of GSH-mediated transient disulfide formation.

Singh S, Lämmle S, Giese H, Kämmerer S, Meyer-Roxlau S, Alfar EA, Dihazi H, Guan K, El-Armouche A, Richter F.

Sci Rep. 2018 Dec 7;8(1):17711. doi: 10.1038/s41598-018-36267-6.

6.

Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure.

Fischer TH, Eiringhaus J, Dybkova N, Saadatmand A, Pabel S, Weber S, Wang Y, Köhn M, Tirilomis T, Ljubojevic S, Renner A, Gummert J, Maier LS, Hasenfuß G, El-Armouche A, Sossalla S.

Eur J Heart Fail. 2018 Dec;20(12):1673-1685. doi: 10.1002/ejhf.1297. Epub 2018 Sep 7.

PMID:
30191648
7.

Hematopoietic hypoxia-inducible factor 2α deficiency ameliorates pathological retinal neovascularization via modulation of endothelial cell apoptosis.

Korovina I, Neuwirth A, Sprott D, Weber S, Sardar Pasha SPB, Gercken B, Breier G, El-Armouche A, Deussen A, Karl MO, Wielockx B, Chavakis T, Klotzsche-von Ameln A.

FASEB J. 2019 Feb;33(2):1758-1770. doi: 10.1096/fj.201800430R. Epub 2018 Aug 29.

PMID:
30156910
8.

Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation.

Yao C, Veleva T, Scott L Jr, Cao S, Li L, Chen G, Jeyabal P, Pan X, Alsina KM, Abu-Taha I Dr, Ghezelbash S, Reynolds CL, Shen YH, LeMaire SA, Schmitz W, Müller FU, El-Armouche A, Tony Eissa N, Beeton C, Nattel S, Wehrens XHT, Dobrev D, Li N.

Circulation. 2018 Nov 13;138(20):2227-2242. doi: 10.1161/CIRCULATIONAHA.118.035202. Erratum in: Circulation. 2019 Apr 23;139(17):e889.

PMID:
29802206
9.

Continuous monitoring after atrial fibrillation ablation: the LINQ AF study.

Wechselberger S, Kronborg M, Huo Y, Piorkowski J, Neudeck S, Päßler E, El-Armouche A, Richter U, Mayer J, Ulbrich S, Pu L, Kirstein B, Gaspar T, Piorkowski C.

Europace. 2018 Nov 1;20(FI_3):f312-f320. doi: 10.1093/europace/euy038.

10.

MicroRNAs in cardiomyocyte differentiation and maturation.

Alfar EA, El-Armouche A, Guan K.

Cardiovasc Res. 2018 May 1;114(6):779-781. doi: 10.1093/cvr/cvy065. No abstract available.

PMID:
29554224
11.

Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila.

Joos JP, Saadatmand AR, Schnabel C, Viktorinová I, Brand T, Kramer M, Nattel S, Dobrev D, Tomancak P, Backs J, Kleinbongard P, Heusch G, Lorenz K, Koch E, Weber S, El-Armouche A.

Sci Rep. 2018 Feb 13;8(1):2940. doi: 10.1038/s41598-018-21372-3.

12.

Endo-/Epicardial Catheter Ablation of Atrial Fibrillation: Feasibility, Outcome, and Insights Into Arrhythmia Mechanisms.

Piorkowski C, Kronborg M, Hourdain J, Piorkowski J, Kirstein B, Neudeck S, Wechselberger S, Päßler E, Löwen A, El-Armouche A, Mayer J, Ulbrich S, Pu L, Richter U, Gaspar T, Huo Y.

Circ Arrhythm Electrophysiol. 2018 Feb;11(2):e005748. doi: 10.1161/CIRCEP.117.005748.

PMID:
29439000
13.

AAV-9 mediated phosphatase-1 inhibitor-1 overexpression improves cardiac contractility in unchallenged mice but is deleterious in pressure-overload.

Schwab DM, Tilemann L, Bauer R, Heckmann M, Jungmann A, Wagner M, Burgis J, Vettel C, Katus HA, El-Armouche A, Müller OJ.

Gene Ther. 2018 Jan;25(1):13-19. doi: 10.1038/gt.2017.97. Epub 2018 Jan 19.

PMID:
29350681
14.

Post-column infusion of internal standard quantification for liquid chromatography-electrospray ionization-tandem mass spectrometry analysis - Pharmaceuticals in urine as example approach.

Rossmann J, Renner LD, Oertel R, El-Armouche A.

J Chromatogr A. 2018 Feb 2;1535:80-87. doi: 10.1016/j.chroma.2018.01.001. Epub 2018 Jan 2.

PMID:
29306632
15.

A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J.

Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11.

PMID:
29227474
16.

Endothelial Nitric Oxide Synthase-Induced Hypertrophy and Vascular Dysfunction Contribute to the Left Ventricular Dysfunction in Caveolin-1-/- Mice.

Ebner A, Kuerbis N, Brandt A, Zatschler B, Weinert S, Poitz DM, Ebner B, Augstein A, Wunderlich C, El-Armouche A, Strasser RH.

Can J Cardiol. 2017 Dec;33(12):1716-1724. doi: 10.1016/j.cjca.2017.09.015. Epub 2017 Sep 25.

PMID:
29173610
17.

Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4.

Perera RK, Fischer TH, Wagner M, Dewenter M, Vettel C, Bork NI, Maier LS, Conti M, Wess J, El-Armouche A, Hasenfuß G, Nikolaev VO.

Sci Rep. 2017 Nov 9;7(1):15222. doi: 10.1038/s41598-017-15632-x.

18.

Erratum to: Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation.

Meyer-Roxlau S, Lämmle S, Opitz A, Künzel S, Joos JP, Neef S, Sekeres K, Sossalla S, Schöndube F, Alexiou K, Maier LS, Dobrev D, Guan K, Weber S, El-Armouche A.

Basic Res Cardiol. 2017 Sep;112(5):51. doi: 10.1007/s00395-017-0638-x. No abstract available.

PMID:
28688054
19.

PDE2 at the crossway between cAMP and cGMP signalling in the heart.

Weber S, Zeller M, Guan K, Wunder F, Wagner M, El-Armouche A.

Cell Signal. 2017 Oct;38:76-84. doi: 10.1016/j.cellsig.2017.06.020. Epub 2017 Jun 28. Review.

PMID:
28668721
20.

Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation.

Meyer-Roxlau S, Lämmle S, Opitz A, Künzel S, Joos JP, Neef S, Sekeres K, Sossalla S, Schöndube F, Alexiou K, Maier LS, Dobrev D, Guan K, Weber S, El-Armouche A.

Basic Res Cardiol. 2017 Jul;112(4):43. doi: 10.1007/s00395-017-0635-0. Epub 2017 Jun 9. Erratum in: Basic Res Cardiol. 2017 Sep;112(5):51.

PMID:
28597249
21.

Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure.

Dewenter M, Neef S, Vettel C, Lämmle S, Beushausen C, Zelarayan LC, Katz S, von der Lieth A, Meyer-Roxlau S, Weber S, Wieland T, Sossalla S, Backs J, Brown JH, Maier LS, El-Armouche A.

Circ Heart Fail. 2017 May;10(5):e003840. doi: 10.1161/CIRCHEARTFAILURE.117.003840.

22.

Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity.

Neef S, Heijman J, Otte K, Dewenter M, Saadatmand AR, Meyer-Roxlau S, Antos CL, Backs J, Dobrev D, Wagner M, Maier LS, El-Armouche A.

Naunyn Schmiedebergs Arch Pharmacol. 2017 Aug;390(8):857-862. doi: 10.1007/s00210-017-1376-1. Epub 2017 Apr 27.

PMID:
28451724
23.

Sex-difference in expression and function of beta-adrenoceptors in macrovessels: role of the endothelium.

Al-Gburi S, Deussen A, Zatschler B, Weber S, Künzel S, El-Armouche A, Lorenz K, Cybularz M, Morawietz H, Kopaliani I.

Basic Res Cardiol. 2017 May;112(3):29. doi: 10.1007/s00395-017-0617-2. Epub 2017 Apr 7.

PMID:
28389717
24.

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.

Abu-Taha IH, Heijman J, Hippe HJ, Wolf NM, El-Armouche A, Nikolaev VO, Schäfer M, Würtz CM, Neef S, Voigt N, Baczkó I, Varró A, Müller M, Meder B, Katus HA, Spiger K, Vettel C, Lehmann LH, Backs J, Skolnik EY, Lutz S, Dobrev D, Wieland T.

Circulation. 2017 Feb 28;135(9):881-897. doi: 10.1161/CIRCULATIONAHA.116.022852. Epub 2016 Dec 7.

PMID:
27927712
25.

Comment on Ferrannini et al. CV Protection in the EMPA-REG OUTCOME Trial: A "Thrifty Substrate" Hypothesis. Diabetes Care 2016;39:1108-1114.

Jordan J, El-Armouche A, Hanefeld M, Bornstein SR, Birkenfeld AL.

Diabetes Care. 2016 Dec;39(12):e224-e225. No abstract available.

PMID:
27879363
26.

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.

Vettel C, Lindner M, Dewenter M, Lorenz K, Schanbacher C, Riedel M, Lämmle S, Meinecke S, Mason FE, Sossalla S, Geerts A, Hoffmann M, Wunder F, Brunner FJ, Wieland T, Mehel H, Karam S, Lechêne P, Leroy J, Vandecasteele G, Wagner M, Fischmeister R, El-Armouche A.

Circ Res. 2017 Jan 6;120(1):120-132. doi: 10.1161/CIRCRESAHA.116.310069. Epub 2016 Oct 31.

PMID:
27799254
27.

LATITUDE-TIMI: is there still hope for anti-inflammatory therapy in acute myocardial infaction?

Dewenter M, Wagner M, El-Armouche A.

J Thorac Dis. 2016 Sep;8(9):E1047-E1049. No abstract available.

28.

[Monoclonal antibodies, overview and outlook of a promising therapeutic option].

Herschel T, El-Armouche A, Weber S.

Dtsch Med Wochenschr. 2016 Sep;141(19):1390-4. doi: 10.1055/s-0042-102980. Epub 2016 Sep 19. Review. German.

PMID:
27642741
29.

Role of protein phosphatase inhibitor-1 in cardiac beta adrenergic pathway.

Weber S, Meyer-Roxlau S, El-Armouche A.

J Mol Cell Cardiol. 2016 Dec;101:116-126. doi: 10.1016/j.yjmcc.2016.09.007. Epub 2016 Sep 14. Review.

PMID:
27639308
30.

Phosphodiesterase 2: anti-adrenergic friend or hypertrophic foe in heart disease?

Wagner M, Mehel H, Fischmeister R, El-Armouche A.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Nov;389(11):1139-1141. Epub 2016 Aug 24. No abstract available.

PMID:
27553701
31.

Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice.

Swain L, Kesemeyer A, Meyer-Roxlau S, Vettel C, Zieseniss A, Güntsch A, Jatho A, Becker A, Nanadikar MS, Morgan B, Dennerlein S, Shah AM, El-Armouche A, Nikolaev VO, Katschinski DM.

Circ Res. 2016 Oct 14;119(9):1004-1016. Epub 2016 Aug 23.

PMID:
27553648
32.

[PCSK9 Inhibitors - the magic bullet for LDL cholesterol reduction?].

Richter K, Barthel A, Bornstein SR, El-Armouche A, Wagner M.

Dtsch Med Wochenschr. 2016 Jun;141(12):863-9. doi: 10.1055/s-0042-102801. Epub 2016 Jun 15. German.

PMID:
27305302
33.

[Off-label-drug-use: Scientific evidence counts].

Wagner M, El-Armouche A.

Dtsch Med Wochenschr. 2016 Mar;141(5):307. doi: 10.1055/s-0042-101364. Epub 2016 Mar 3. German. No abstract available.

PMID:
26939091
34.

Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein Phosphatases.

Weber S, Meyer-Roxlau S, Wagner M, Dobrev D, El-Armouche A.

Front Pharmacol. 2015 Nov 13;6:270. doi: 10.3389/fphar.2015.00270. eCollection 2015. Review.

35.

Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation.

García-Martín R, Alexaki VI, Qin N, Rubín de Celis MF, Economopoulou M, Ziogas A, Gercken B, Kotlabova K, Phieler J, Ehrhart-Bornstein M, Bornstein SR, Eisenhofer G, Breier G, Blüher M, Hampe J, El-Armouche A, Chatzigeorgiou A, Chung KJ, Chavakis T.

Mol Cell Biol. 2015 Nov 16;36(3):376-93. doi: 10.1128/MCB.00430-15. Print 2016 Feb 1.

36.

I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model.

Friedrich FW, Sotoud H, Geertz B, Weber S, Flenner F, Reischmann S, Eschenhagen T, Carrier L, El-Armouche A.

Int J Cardiol Heart Vasc. 2015 May 29;8:87-94. doi: 10.1016/j.ijcha.2015.05.010. eCollection 2015 Sep 1.

37.

Linking superinhibitory PLN mutations to CaMKII activation: a new arrhythmogenic mechanism in genetic DCM?

Wagner M, Weber S, El-Armouche A.

Cardiovasc Res. 2015 Jul 1;107(1):5-6. doi: 10.1093/cvr/cvv163. Epub 2015 May 26. No abstract available.

PMID:
26014576
38.

Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation.

Godier-Furnémont AF, Tiburcy M, Wagner E, Dewenter M, Lämmle S, El-Armouche A, Lehnart SE, Vunjak-Novakovic G, Zimmermann WH.

Biomaterials. 2015 Aug;60:82-91. doi: 10.1016/j.biomaterials.2015.03.055. Epub 2015 May 15.

39.

Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy.

Perera RK, Sprenger JU, Steinbrecher JH, Hübscher D, Lehnart SE, Abesser M, Schuh K, El-Armouche A, Nikolaev VO.

Circ Res. 2015 Apr 10;116(8):1304-11. doi: 10.1161/CIRCRESAHA.116.306082. Epub 2015 Feb 16.

PMID:
25688144
40.

Development of phosphatase inhibitor-1 peptides acting as indirect activators of phosphatase 1.

Sotoud H, Borgmeyer U, Schulze C, El-Armouche A, Eschenhagen T.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Mar;388(3):283-93. doi: 10.1007/s00210-014-1065-2. Epub 2014 Nov 23.

PMID:
25416155
41.

Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes.

Neuber C, Uebeler J, Schulze T, Sotoud H, El-Armouche A, Eschenhagen T.

PLoS One. 2014 Jun 3;9(6):e98893. doi: 10.1371/journal.pone.0098893. eCollection 2014.

42.

Erythropoietin responsive cardiomyogenic cells contribute to heart repair post myocardial infarction.

Zafiriou MP, Noack C, Unsöld B, Didie M, Pavlova E, Fischer HJ, Reichardt HM, Bergmann MW, El-Armouche A, Zimmermann WH, Zelarayan LC.

Stem Cells. 2014 Sep;32(9):2480-91. doi: 10.1002/stem.1741.

43.

[Tofacitinib].

Döker S, Dewenter M, El-Armouche A.

Dtsch Med Wochenschr. 2014 May;139(19):1003-8. doi: 10.1055/s-0034-1369986. Epub 2014 Apr 29. Review. German.

PMID:
24782154
44.

The Janus face of BNP therapy in chronic heart failure: beneficial effects unmasked by β blockers?

Dewenter M, Vettel C, El-Armouche A.

Heart. 2014 Jun;100(11):819-20. doi: 10.1136/heartjnl-2014-305503. Epub 2014 Mar 25. No abstract available.

PMID:
24667282
45.

Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes.

Haj Slimane Z, Bedioune I, Lechêne P, Varin A, Lefebvre F, Mateo P, Domergue-Dupont V, Dewenter M, Richter W, Conti M, El-Armouche A, Zhang J, Fischmeister R, Vandecasteele G.

Cardiovasc Res. 2014 Apr 1;102(1):97-106. doi: 10.1093/cvr/cvu029. Epub 2014 Feb 18.

46.

PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways.

Vettel C, Lämmle S, Ewens S, Cervirgen C, Emons J, Ongherth A, Dewenter M, Lindner D, Westermann D, Nikolaev VO, Lutz S, Zimmermann WH, El-Armouche A.

Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1246-52. doi: 10.1152/ajpheart.00852.2013. Epub 2014 Feb 14.

47.

Paradoxical effects on force generation after efficient β1-adrenoceptor knockdown in reconstituted heart tissue.

Neuber C, Müller OJ, Hansen FC, Eder A, Witten A, Rühle F, Stoll M, Katus HA, Eschenhagen T, El-Armouche A.

J Pharmacol Exp Ther. 2014 Apr;349(1):39-46. doi: 10.1124/jpet.113.210898. Epub 2014 Jan 15.

PMID:
24431469
48.

Dopamine and lipophilic derivates protect cardiomyocytes against cold preservation injury.

Vettel C, Hottenrott MC, Spindler R, Benck U, Schnuelle P, Tsagogiorgas C, Krämer BK, Hoeger S, El-Armouche A, Wieland T, Yard BA.

J Pharmacol Exp Ther. 2014 Jan;348(1):77-85. doi: 10.1124/jpet.113.207001. Epub 2013 Oct 17.

PMID:
24135075
49.

Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction.

Unsöld B, Kaul A, Sbroggiò M, Schubert C, Regitz-Zagrosek V, Brancaccio M, Damilano F, Hirsch E, Van Bilsen M, Munts C, Sipido K, Bito V, Detre E, Wagner NM, Schäfer K, Seidler T, Vogt J, Neef S, Bleckmann A, Maier LS, Balligand JL, Bouzin C, Ventura-Clapier R, Garnier A, Eschenhagen T, El-Armouche A, Knöll R, Tarone G, Hasenfuß G.

Cardiovasc Res. 2014 Jan 1;101(1):97-107. doi: 10.1093/cvr/cvt235. Epub 2013 Oct 15.

50.

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart.

Heijman J, Dewenter M, El-Armouche A, Dobrev D.

J Mol Cell Cardiol. 2013 Nov;64:90-8. doi: 10.1016/j.yjmcc.2013.09.006. Epub 2013 Sep 16. Review.

PMID:
24051368

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