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Items: 12


Improved segmented-scan spectral stitching for stable isotope resolved metabolomics (SIRM) by ultra-high-resolution Fourier transform mass spectrometry.

Kang WY, Thompson PT, El-Amouri SS, Fan TWM, Lane AN, Higashi RM.

Anal Chim Acta. 2019 Nov 8;1080:104-115. doi: 10.1016/j.aca.2019.06.019. Epub 2019 Jun 11.


Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis.

Che L, Yang X, Ge C, El-Amouri SS, Wang QE, Pan D, Herzog TJ, Du C.

PLoS One. 2019 May 15;14(5):e0216553. doi: 10.1371/journal.pone.0216553. eCollection 2019.


Getting the Most: Enhancing Efficacy by Promoting Erythropoiesis and Thrombopoiesis after Gene Therapy in Mice with Hurler Syndrome.

Han JF, El-Amouri SS, Dai M, Cao P, Pan D.

Mol Ther Methods Clin Dev. 2018 Oct 10;11:52-64. doi: 10.1016/j.omtm.2018.10.001. eCollection 2018 Dec 14.


Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids versus 2D Cell Cultures.

Fan TW, El-Amouri SS, Macedo JKA, Wang QJ, Song H, Cassel T, Lane AN.

Metabolites. 2018 Jul 10;8(3). pii: E40. doi: 10.3390/metabo8030040.


Comprehensive evaluation of blood-brain barrier-forming micro-vasculatures: Reference and marker genes with cellular composition.

Dai M, Lin Y, El-Amouri SS, Kohls M, Pan D.

PLoS One. 2018 May 15;13(5):e0197379. doi: 10.1371/journal.pone.0197379. eCollection 2018.


Normalization and improvement of CNS deficits in mice with Hurler syndrome after long-term peripheral delivery of BBB-targeted iduronidase.

El-Amouri SS, Dai M, Han JF, Brady RO, Pan D.

Mol Ther. 2014 Dec;22(12):2028-37. doi: 10.1038/mt.2014.152. Epub 2014 Aug 4.


Platelets are efficient and protective depots for storage, distribution, and delivery of lysosomal enzyme in mice with Hurler syndrome.

Dai M, Han J, El-Amouri SS, Brady RO, Pan D.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2680-5. doi: 10.1073/pnas.1323155111. Epub 2014 Feb 3.


Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier.

Wang D, El-Amouri SS, Dai M, Kuan CY, Hui DY, Brady RO, Pan D.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2999-3004. doi: 10.1073/pnas.1222742110. Epub 2013 Feb 4.


Secreted luciferase for in vivo evaluation of systemic protein delivery in mice.

El-Amouri SS, Cao P, Miao C, Pan D.

Mol Biotechnol. 2013 Jan;53(1):63-73. doi: 10.1007/s12033-012-9519-6.


Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.

El-Amouri SS, Zhu H, Yu J, Marr R, Verma IM, Kindy MS.

Am J Pathol. 2008 May;172(5):1342-54. doi: 10.2353/ajpath.2008.070620. Epub 2008 Apr 10.


Neprilysin protects neurons against Abeta peptide toxicity.

El-Amouri SS, Zhu H, Yu J, Gage FH, Verma IM, Kindy MS.

Brain Res. 2007 Jun 4;1152:191-200. Epub 2007 Mar 28.

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