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Items: 9


The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis.

Aprelikova O, Chen K, El Touny LH, Brignatz-Guittard C, Han J, Qiu T, Yang HH, Lee MP, Zhu M, Green JE.

Clin Epigenetics. 2016 Apr 14;8:38. doi: 10.1186/s13148-016-0205-6. eCollection 2016.


Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells.

El Touny LH, Vieira A, Mendoza A, Khanna C, Hoenerhoff MJ, Green JE.

J Clin Invest. 2014 Jan;124(1):156-68. doi: 10.1172/JCI70259. Epub 2013 Dec 9.


Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß.

Chu IM, Lai WC, Aprelikova O, El Touny LH, Kouros-Mehr H, Green JE.

PLoS One. 2013;8(4):e61125. doi: 10.1371/journal.pone.0061125. Epub 2013 Apr 8.


Biochanin A reduces drug-induced p75NTR expression and enhances cell survival: a new in vitro assay for screening inhibitors of p75NTR expression.

El Touny LH, Henderson F, Djakiew D.

Rejuvenation Res. 2010 Oct;13(5):527-37. doi: 10.1089/rej.2009.1006. Epub 2010 Sep 6.


Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment.

Barkan D, El Touny LH, Michalowski AM, Smith JA, Chu I, Davis AS, Webster JD, Hoover S, Simpson RM, Gauldie J, Green JE.

Cancer Res. 2010 Jul 15;70(14):5706-16. doi: 10.1158/0008-5472.CAN-09-2356. Epub 2010 Jun 22.


Identification of a biphasic role for genistein in the regulation of prostate cancer growth and metastasis.

El Touny LH, Banerjee PP.

Cancer Res. 2009 Apr 15;69(8):3695-703. doi: 10.1158/0008-5472.CAN-08-2958. Epub 2009 Apr 7.


Genistein induces the metastasis suppressor kangai-1 which mediates its anti-invasive effects in TRAMP cancer cells.

El Touny LH, Banerjee PP.

Biochem Biophys Res Commun. 2007 Sep 14;361(1):169-75. Epub 2007 Jul 16.


Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3.

Chau MN, El Touny LH, Jagadeesh S, Banerjee PP.

Carcinogenesis. 2007 Nov;28(11):2282-90. Epub 2007 Jul 5.


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