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Items: 20

1.

Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma.

Wei BR, Michael HT, Halsey CH, Peer CJ, Adhikari A, Dwyer JE, Hoover SB, El Meskini R, Kozlov S, Weaver Ohler Z, Figg WD, Merlino G, Simpson RM.

Pigment Cell Melanoma Res. 2016 Nov;29(6):643-655. doi: 10.1111/pcmr.12512. Epub 2016 Sep 22.

2.

A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors.

El Meskini R, Iacovelli AJ, Kulaga A, Gumprecht M, Martin PL, Baran M, Householder DB, Van Dyke T, Weaver Ohler Z.

Dis Model Mech. 2015 Jan;8(1):45-56. doi: 10.1242/dmm.018168. Epub 2014 Nov 27.

3.

"Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts.

Day CP, Carter J, Weaver Ohler Z, Bonomi C, El Meskini R, Martin P, Graff-Cherry C, Feigenbaum L, Tüting T, Van Dyke T, Hollingshead M, Merlino G.

PLoS One. 2014 Nov 4;9(11):e109956. doi: 10.1371/journal.pone.0109956. eCollection 2014.

4.

Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response.

Weaver Z, Difilippantonio S, Carretero J, Martin PL, El Meskini R, Iacovelli AJ, Gumprecht M, Kulaga A, Guerin T, Schlomer J, Baran M, Kozlov S, McCann T, Mena S, Al-Shahrour F, Alexander D, Wong KK, Van Dyke T.

Cancer Res. 2012 Nov 15;72(22):5921-33. doi: 10.1158/0008-5472.CAN-12-0736. Epub 2012 Sep 11.

5.

Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity.

Kuhajda FP, Aja S, Tu Y, Han WF, Medghalchi SM, El Meskini R, Landree LE, Peterson JM, Daniels K, Wong K, Wydysh EA, Townsend CA, Ronnett GV.

Am J Physiol Regul Integr Comp Physiol. 2011 Jul;301(1):R116-30. doi: 10.1152/ajpregu.00147.2011. Epub 2011 Apr 13.

6.

Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease.

Niciu MJ, Ma XM, El Meskini R, Pachter JS, Mains RE, Eipper BA.

Neurobiol Dis. 2007 Sep;27(3):278-91. Epub 2007 May 23.

7.

Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells.

Zhou W, Han WF, Landree LE, Thupari JN, Pinn ML, Bililign T, Kim EK, Vadlamudi A, Medghalchi SM, El Meskini R, Ronnett GV, Townsend CA, Kuhajda FP.

Cancer Res. 2007 Apr 1;67(7):2964-71.

8.

ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis.

El Meskini R, Crabtree KL, Cline LB, Mains RE, Eipper BA, Ronnett GV.

Mol Cell Neurosci. 2007 Mar;34(3):409-21. Epub 2007 Jan 9.

9.

Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP- and PACAP-deficient mice.

Girard BA, Lelievre V, Braas KM, Razinia T, Vizzard MA, Ioffe Y, El Meskini R, Ronnett GV, Waschek JA, May V.

J Neurochem. 2006 Oct;99(2):499-513.

10.

Developmental changes in the expression of ATP7A during a critical period in postnatal neurodevelopment.

Niciu MJ, Ma XM, El Meskini R, Ronnett GV, Mains RE, Eipper BA.

Neuroscience. 2006;139(3):947-64. Epub 2006 Mar 23.

PMID:
16549268
11.

The developmentally regulated expression of Menkes protein ATP7A suggests a role in axon extension and synaptogenesis.

El Meskini R, Cline LB, Eipper BA, Ronnett GV.

Dev Neurosci. 2005;27(5):333-48.

PMID:
16137991
12.

Mechanistic investigation of peptidylglycine alpha-hydroxylating monooxygenase via intrinsic tryptophan fluorescence and mutagenesis.

Bell J, El Meskini R, D'Amato D, Mains RE, Eipper BA.

Biochemistry. 2003 Jun 17;42(23):7133-42.

PMID:
12795609
13.

Supplying copper to the cuproenzyme peptidylglycine alpha-amidating monooxygenase.

El Meskini R, Culotta VC, Mains RE, Eipper BA.

J Biol Chem. 2003 Apr 4;278(14):12278-84. Epub 2003 Jan 14.

14.

A signal sequence is sufficient for green fluorescent protein to be routed to regulated secretory granules.

El Meskini R, Jin L, Marx R, Bruzzaniti A, Lee J, Emeson R, Mains R.

Endocrinology. 2001 Feb;142(2):864-73.

PMID:
11159860
15.

Targeting of membrane proteins to the regulated secretory pathway in anterior pituitary endocrine cells.

El Meskini R, Galano GJ, Marx R, Mains RE, Eipper BA.

J Biol Chem. 2001 Feb 2;276(5):3384-93. Epub 2000 Nov 1.

16.

Cell type-specific metabolism of peptidylglycine alpha-amidating monooxygenase in anterior pituitary.

El Meskini R, Mains RE, Eipper BA.

Endocrinology. 2000 Aug;141(8):3020-34.

PMID:
10919291
18.

Evidence of high expression of peptidylglycine alpha-amidating monooxygenase in the rat uterus: estrogen regulation.

El Meskini R, Delfino C, Boudouresque F, Oliver C, Martin PM, Ouafik L'H.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7191-6.

19.
20.

Estrogen regulation of peptidylglycine alpha-amidating monooxygenase expression in anterior pituitary gland.

el Meskini R, Delfino C, Boudouresque F, Hery M, Oliver C, Ouafik L.

Endocrinology. 1997 Jan;138(1):379-88.

PMID:
8977427

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