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Items: 15


MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells.

Merkenschlager J, Eksmond U, Danelli L, Attig J, Young GR, Nowosad C, Tolar P, Kassiotis G.

Blood. 2019 Mar 7;133(10):1108-1118. doi: 10.1182/blood-2018-11-885467. Epub 2019 Jan 30.


Restoration of Endogenous Retrovirus Infectivity Impacts Mouse Cancer Models.

Ottina E, Levy P, Eksmond U, Merkenschlager J, Young GR, Roels J, Stoye JP, Tüting T, Calado DP, Kassiotis G.

Cancer Immunol Res. 2018 Nov;6(11):1292-1300. doi: 10.1158/2326-6066.CIR-18-0038. Epub 2018 Aug 24.


Mutation of the Putative Immunosuppressive Domain of the Retroviral Envelope Glycoprotein Compromises Infectivity.

Eksmond U, Jenkins B, Merkenschlager J, Mothes W, Stoye JP, Kassiotis G.

J Virol. 2017 Oct 13;91(21). pii: e01152-17. doi: 10.1128/JVI.01152-17. Print 2017 Nov 1.


Antigenicity of peptides comprising the immunosuppressive domain of the retroviral envelope glycoprotein.

Jenkins B, Eksmond U, Young G, Kassiotis G.

Wellcome Open Res. 2016 Dec 6;1:22. doi: 10.12688/wellcomeopenres.10269.2.


Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus.

Donnarumma T, Young GR, Merkenschlager J, Eksmond U, Bongard N, Nutt SL, Boyer C, Dittmer U, Le-Trilling VT, Trilling M, Bayer W, Kassiotis G.

Cell Rep. 2016 Nov 1;17(6):1571-1583. doi: 10.1016/j.celrep.2016.10.013.


Dichotomy between T Cell and B Cell Tolerance to Neonatal Retroviral Infection Permits T Cell Therapy.

Mavrommatis B, Baudino L, Levy P, Merkenschlager J, Eksmond U, Donnarumma T, Young G, Stoye J, Kassiotis G.

J Immunol. 2016 Nov 1;197(9):3628-3638. Epub 2016 Sep 19.


Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response.

Merkenschlager J, Ploquin MJ, Eksmond U, Andargachew R, Thorborn G, Filby A, Pepper M, Evavold B, Kassiotis G.

Nat Commun. 2016 Jan 5;7:10281. doi: 10.1038/ncomms10281.


Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.

Thorborn G, Ploquin MJ, Eksmond U, Pike R, Bayer W, Dittmer U, Hasenkrug KJ, Pepper M, Kassiotis G.

J Immunol. 2014 Aug 15;193(4):1567-77. doi: 10.4049/jimmunol.1400667. Epub 2014 Jul 7.


Resurrection of endogenous retroviruses in antibody-deficient mice.

Young GR, Eksmond U, Salcedo R, Alexopoulou L, Stoye JP, Kassiotis G.

Nature. 2012 Nov 29;491(7426):774-8. doi: 10.1038/nature11599. Epub 2012 Oct 24.


Negative impact of IFN-γ on early host immune responses to retroviral infection.

Duley AK, Ploquin MJ, Eksmond U, Ammann CG, Messer RJ, Myers L, Hasenkrug KJ, Kassiotis G.

J Immunol. 2012 Sep 1;189(5):2521-9. doi: 10.4049/jimmunol.1201125. Epub 2012 Jul 20.


Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection.

Young GR, Ploquin MJ, Eksmond U, Wadwa M, Stoye JP, Kassiotis G.

PLoS Pathog. 2012;8(5):e1002709. doi: 10.1371/journal.ppat.1002709. Epub 2012 May 10.


B cells and TCR avidity determine distinct functions of CD4+ T cells in retroviral infection.

Ploquin MJ, Eksmond U, Kassiotis G.

J Immunol. 2011 Sep 15;187(6):3321-30. doi: 10.4049/jimmunol.1101006. Epub 2011 Aug 12.


Generalized immune activation as a direct result of activated CD4+ T cell killing.

Marques R, Williams A, Eksmond U, Wullaert A, Killeen N, Pasparakis M, Kioussis D, Kassiotis G.

J Biol. 2009;8(10):93. doi: 10.1186/jbiol194.


Race between retroviral spread and CD4+ T-cell response determines the outcome of acute Friend virus infection.

Pike R, Filby A, Ploquin MJ, Eksmond U, Marques R, Antunes I, Hasenkrug K, Kassiotis G.

J Virol. 2009 Nov;83(21):11211-22. doi: 10.1128/JVI.01225-09. Epub 2009 Aug 19.


B lymphocyte activation by coinfection prevents immune control of friend virus infection.

Marques R, Antunes I, Eksmond U, Stoye J, Hasenkrug K, Kassiotis G.

J Immunol. 2008 Sep 1;181(5):3432-40.

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