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Items: 22


Local and systemic Curcumin C3 complex inhibits 4NQO-induced oral tumorigenesis via modulating FGF-2/FGFR-2 activation.

Khandelwal AR, Moore-Medlin T, Ekshyyan O, Gu X, Abreo F, Nathan CO.

Am J Cancer Res. 2018 Dec 1;8(12):2538-2547. eCollection 2018.


Survival outcomes based on systemic agent used concurrently with radiation in human-papillomavirus associated oropharyngeal cancer.

Mehta V, Moore-Medlin T, Flores JM, Ma X, Ekshyyan O, Nathan CO.

Oncotarget. 2017 Aug 10;8(41):70907-70915. doi: 10.18632/oncotarget.20197. eCollection 2017 Sep 19.


Rapamycin targets Interleukin 6 (IL-6) expression and suppresses endothelial cell invasion stimulated by tumor cells.

Ekshyyan O, Khandelwal AR, Rong X, Moore-Medlin T, Ma X, Alexander JS, Nathan CO.

Am J Transl Res. 2016 Nov 15;8(11):4822-4830. eCollection 2016.


Photopreventive Effect and Mechanism of AZD4547 and Curcumin C3 Complex on UVB-Induced Epidermal Hyperplasia.

Khandelwal AR, Rong X, Moore-Medlin T, Ekshyyan O, Abreo F, Gu X, Nathan CA.

Cancer Prev Res (Phila). 2016 Apr;9(4):296-304. doi: 10.1158/1940-6207.CAPR-15-0366. Epub 2016 Feb 9.


Enhanced Systemic Bioavailability of Curcumin Through Transmucosal Administration of a Novel Microgranular Formulation.

Latimer B, Ekshyyan O, Nathan N, Moore-Medlin T, Rong X, Ma X, Khandelwal A, Christy HT, Abreo F, McClure G, Vanchiere JA, Caldito G, Dugas T, McMartin K, Lian T, Mehta V, Nathan CA.

Anticancer Res. 2015 Dec;35(12):6411-8.


EBV and not HPV sensitizes tobacco-associated head and neck cancer cell line FaDu to radiotherapy.

Anandharaj A, Ekshyyan O, Jia Y, Rong X, Harrison L, Shi R, Scott RS, Nathan CA.

Acta Otolaryngol. 2016;136(4):354-62. doi: 10.3109/00016489.2015.1114182. Epub 2015 Dec 4.


Association between human papilloma virus/Epstein-Barr virus coinfection and oral carcinogenesis.

Jiang R, Ekshyyan O, Moore-Medlin T, Rong X, Nathan S, Gu X, Abreo F, Rosenthal EL, Shi M, Guidry JT, Scott RS, Hutt-Fletcher LM, Nathan CA.

J Oral Pathol Med. 2015 Jan;44(1):28-36. doi: 10.1111/jop.12221. Epub 2014 Jul 18.


Serum biomarkers in head and neck squamous cell cancer.

Kaskas NM, Moore-Medlin T, McClure GB, Ekshyyan O, Vanchiere JA, Nathan CA.

JAMA Otolaryngol Head Neck Surg. 2014 Jan;140(1):5-11. doi: 10.1001/jamaoto.2013.5688.


Anti-lymphangiogenic properties of mTOR inhibitors in head and neck squamous cell carcinoma experimental models.

Ekshyyan O, Moore-Medlin TN, Raley MC, Sonavane K, Rong X, Brodt MA, Abreo F, Alexander JS, Nathan CA.

BMC Cancer. 2013 Jul 1;13:320. doi: 10.1186/1471-2407-13-320.


Dual PI3K/mTOR inhibitors: does p53 modulate response?

Ekshyyan O, Anandharaj A, Nathan CA.

Clin Cancer Res. 2013 Jul 15;19(14):3719-21. doi: 10.1158/1078-0432.CCR-13-1291. Epub 2013 Jun 5.


Curcumin inhibits UV radiation-induced skin cancer in SKH-1 mice.

Phillips J, Moore-Medlin T, Sonavane K, Ekshyyan O, McLarty J, Nathan CA.

Otolaryngol Head Neck Surg. 2013 May;148(5):797-803. doi: 10.1177/0194599813476845. Epub 2013 Feb 5.


Topical curcumin-based cream is equivalent to dietary curcumin in a skin cancer model.

Sonavane K, Phillips J, Ekshyyan O, Moore-Medlin T, Roberts Gill J, Rong X, Lakshmaiah RR, Abreo F, Boudreaux D, Clifford JL, Nathan CA.

J Skin Cancer. 2012;2012:147863. doi: 10.1155/2012/147863. Epub 2012 Dec 13.


18F-fluorodeoxythymidine micro-positron-emission tomography versus 18F-fluorodeoxyglucose micro-positron-emission tomography for in vivo minimal residual disease imaging.

Ekshyyan O, Sibley D, Caldito GC, Sunderland J, Vascoe C, Nathan CA.

Laryngoscope. 2013 Jan;123(1):107-11. doi: 10.1002/lary.23600. Epub 2012 Sep 27.


Efficacy and comparative effectiveness of sirolimus as an anticancer drug.

Hu M, Ekshyyan O, Herman Ferdinandez L, Rong X, Caldito G, Nathan CO.

Laryngoscope. 2011 May;121(5):978-82. doi: 10.1002/lary.21724.


Teasing out the best molecular marker in the AKT/mTOR pathway in head and neck squamous cell cancer patients.

Clark C, Shah S, Herman-Ferdinandez L, Ekshyyan O, Abreo F, Rong X, McLarty J, Lurie A, Milligan EJ, Nathan CO.

Laryngoscope. 2010 Jun;120(6):1159-65. doi: 10.1002/lary.20917.


Pharmacodynamic evaluation of temsirolimus in patients with newly diagnosed advanced-stage head and neck squamous cell carcinoma.

Ekshyyan O, Mills GM, Lian T, Amirghahari N, Rong X, Lowery-Nordberg M, Abreo F, Veillon DM, Caldito G, Speicher L, Glass J, Nathan CO.

Head Neck. 2010 Dec;32(12):1619-28. doi: 10.1002/hed.21374.


Comparison of radiosensitizing effects of the mammalian target of rapamycin inhibitor CCI-779 to cisplatin in experimental models of head and neck squamous cell carcinoma.

Ekshyyan O, Rong Y, Rong X, Pattani KM, Abreo F, Caldito G, Chang JK, Ampil F, Glass J, Nathan CO.

Mol Cancer Ther. 2009 Aug;8(8):2255-65. doi: 10.1158/1535-7163.MCT-08-1184. Epub 2009 Jul 22.


Neuronal apoptosis in neurodegeneration.

Okouchi M, Ekshyyan O, Maracine M, Aw TY.

Antioxid Redox Signal. 2007 Aug;9(8):1059-96. Review.


Apoptosis: a key in neurodegenerative disorders.

Ekshyyan O, Aw TY.

Curr Neurovasc Res. 2004 Oct;1(4):355-71. Review.


Apoptosis in acute and chronic neurological disorders.

Ekshyyan O, Aw TY.

Front Biosci. 2004 May 1;9:1567-76. Review.


Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells.

Pias EK, Ekshyyan OY, Rhoads CA, Fuseler J, Harrison L, Aw TY.

J Biol Chem. 2003 Apr 11;278(15):13294-301. Epub 2003 Jan 27.

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