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Items: 1 to 50 of 160

1.

The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins.

Thierer JH, Ekker SC, Farber SA.

Nat Commun. 2019 Jul 31;10(1):3426. doi: 10.1038/s41467-019-11259-w.

2.

Taking a closer look at whole organisms.

Ichino N, Ekker SC.

Elife. 2019 Jun 14;8. pii: e48340. doi: 10.7554/eLife.48340.

3.

The Gene Sculpt Suite: a set of tools for genome editing.

Mann CM, Martínez-Gálvez G, Welker JM, Wierson WA, Ata H, Almeida MP, Clark KJ, Essner JJ, McGrail M, Ekker SC, Dobbs D.

Nucleic Acids Res. 2019 Jul 2;47(W1):W175-W182. doi: 10.1093/nar/gkz405.

4.

CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies.

Mochel JP, Ekker SC, Johannes CM, Jergens AE, Allenspach K, Bourgois-Mochel A, Knouse M, Benzekry S, Wierson W, LeBlanc AK, Kenderian SS.

AAPS J. 2019 Apr 8;21(3):50. doi: 10.1208/s12248-019-0322-1.

PMID:
30963322
5.

Workshop Report: Zebrafish and Other Fish Models-Description of Extrinsic Environmental Factors for Rigorous Experiments and Reproducible Results.

Varga ZM, Ekker SC, Lawrence C.

Zebrafish. 2018 Dec;15(6):533-535. doi: 10.1089/zeb.2018.29006.zol.

PMID:
30496034
6.

Case-Based Learning in Translational Biomedical Research Education: Providing Realistic and Adaptive Skills for Early-Career Scientists.

Greenberg-Worisek AJ, Campbell KA, Klee EW, Staff NP, Schimmenti LA, Weavers KM, Ekker SC, Windebank AJ.

Acad Med. 2019 Feb;94(2):213-216. doi: 10.1097/ACM.0000000000002470.

PMID:
30256254
7.

Humidity as a non-pharmaceutical intervention for influenza A.

Reiman JM, Das B, Sindberg GM, Urban MD, Hammerlund MEM, Lee HB, Spring KM, Lyman-Gingerich J, Generous AR, Koep TH, Ewing K, Lilja P, Enders FT, Ekker SC, Huskins WC, Fadel HJ, Pierret C.

PLoS One. 2018 Sep 25;13(9):e0204337. doi: 10.1371/journal.pone.0204337. eCollection 2018.

8.

Robust activation of microhomology-mediated end joining for precision gene editing applications.

Ata H, Ekstrom TL, Martínez-Gálvez G, Mann CM, Dvornikov AV, Schaefbauer KJ, Ma AC, Dobbs D, Clark KJ, Ekker SC.

PLoS Genet. 2018 Sep 12;14(9):e1007652. doi: 10.1371/journal.pgen.1007652. eCollection 2018 Sep.

9.

tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish.

Ignatius MS, Hayes MN, Moore FE, Tang Q, Garcia SP, Blackburn PR, Baxi K, Wang L, Jin A, Ramakrishnan A, Reeder S, Chen Y, Nielsen GP, Chen EY, Hasserjian RP, Tirode F, Ekker SC, Langenau DM.

Elife. 2018 Sep 7;7. pii: e37202. doi: 10.7554/eLife.37202.

10.

Precision gene editing technology and applications in nephrology.

WareJoncas Z, Campbell JM, Martínez-Gálvez G, Gendron WAC, Barry MA, Harris PC, Sussman CR, Ekker SC.

Nat Rev Nephrol. 2018 Nov;14(11):663-677. doi: 10.1038/s41581-018-0047-x. Review.

11.

Fishing for understanding: Unlocking the zebrafish gene editor's toolbox.

Simone BW, Martínez-Gálvez G, WareJoncas Z, Ekker SC.

Methods. 2018 Nov 1;150:3-10. doi: 10.1016/j.ymeth.2018.07.012. Epub 2018 Aug 2. Review.

12.

Adolescent mental health education InSciEd Out: a case study of an alternative middle school population.

Yang J, Lopez Cervera R, Tye SJ, Ekker SC, Pierret C.

J Transl Med. 2018 Apr 3;16(1):84. doi: 10.1186/s12967-018-1459-x.

13.

Correction: RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells (doi:10.1242/jcs.167601).

Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D.

J Cell Sci. 2018 Mar 16;131(6). pii: jcs217604. doi: 10.1242/jcs.217604. No abstract available.

14.

Guidelines for morpholino use in zebrafish.

Stainier DYR, Raz E, Lawson ND, Ekker SC, Burdine RD, Eisen JS, Ingham PW, Schulte-Merker S, Yelon D, Weinstein BM, Mullins MC, Wilson SW, Ramakrishnan L, Amacher SL, Neuhauss SCF, Meng A, Mochizuki N, Panula P, Moens CB.

PLoS Genet. 2017 Oct 19;13(10):e1007000. doi: 10.1371/journal.pgen.1007000. eCollection 2017 Oct. No abstract available.

15.

A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene.

Ding Y, Long PA, Bos JM, Shih YH, Ma X, Sundsbak RS, Chen J, Jiang Y, Zhao L, Hu X, Wang J, Shi Y, Ackerman MJ, Lin X, Ekker SC, Redfield MM, Olson TM, Xu X.

JCI Insight. 2017 Apr 20;2(8). pii: 94086. doi: 10.1172/jci.insight.94086. eCollection 2017 Apr 20. No abstract available.

16.

Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly.

El-Rass S, Eisa-Beygi S, Khong E, Brand-Arzamendi K, Mauro A, Zhang H, Clark KJ, Ekker SC, Wen XY.

Biol Open. 2017 Mar 15;6(3):348-357. doi: 10.1242/bio.021212.

17.

Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute.

Lee SH, Turchiano G, Ata H, Nowsheen S, Romito M, Lou Z, Ryu SM, Ekker SC, Cathomen T, Kim JS.

Nat Biotechnol. 2016 Nov 28;35(1):17-18. doi: 10.1038/nbt.3753. No abstract available.

18.

A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene.

Ding Y, Long PA, Bos JM, Shih YH, Ma X, Sundsbak RS, Chen J, Jiang Y, Zhao L, Hu X, Wang J, Shi Y, Ackerman MJ, Lin X, Ekker SC, Redfield MM, Olson TM, Xu X.

JCI Insight. 2016 Sep 8;1(14). pii: e88797. Erratum in: JCI Insight. 2017 Apr 20;2(8):.

19.

Promotion of Influenza Prevention Beliefs and Behaviors through Primary School Science Education.

Koep TH, Jenkins S, M Hammerlund ME, Clemens C, Fracica E, Ekker SC, Enders FT, Huskins WC, Pierret C.

J Community Med Health Educ. 2016 Jun;6(3). pii: 444. Epub 2016 Jun 27.

20.

TALEN-Mediated Mutagenesis and Genome Editing.

Ma AC, Chen Y, Blackburn PR, Ekker SC.

Methods Mol Biol. 2016;1451:17-30. doi: 10.1007/978-1-4939-3771-4_2.

21.

The zebrafish genome editing toolkit.

Ata H, Clark KJ, Ekker SC.

Methods Cell Biol. 2016;135:149-70. doi: 10.1016/bs.mcb.2016.04.023. Epub 2016 May 30.

PMID:
27443924
22.

Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated with Liver Cirrhosis and Hepatocellular Carcinoma.

Blackburn PR, Hickey RD, Nace RA, Giama NH, Kraft DL, Bordner AJ, Chaiteerakij R, McCormick JB, Radulovic M, Graham RP, Torbenson MS, Tortorelli S, Scott CR, Lindor NM, Milliner DS, Oglesbee D, Al-Qabandi W, Grompe M, Gavrilov DK, El-Youssef M, Clark KJ, Atwal PS, Roberts LR, Klee EW, Ekker SC.

Hum Mutat. 2016 Oct;37(10):1097-105. doi: 10.1002/humu.23047. Epub 2016 Aug 8.

23.

Universal Healthcare for Zebrafish.

Varga ZM, Lawrence C, Ekker SC, Eisen JS.

Zebrafish. 2016 Jul;13 Suppl 1:S1-4. doi: 10.1089/zeb.2016.1311. No abstract available.

24.

Gene Editing: Practical Application in the Lab.

Geurts AM, Ekker SC.

Hum Gene Ther. 2016 Jun;27(6):417-8. doi: 10.1089/hum.2016.29029.amg. No abstract available. Erratum in: Hum Gene Ther. 2016 Jul;27(7):559.

25.

ssDNA and the Argonautes: The Quest for the Next Golden Editor.

Martínez-Gálvez G, Ata H, Campbell JM, Ekker SC.

Hum Gene Ther. 2016 Jun;27(6):419-22. doi: 10.1089/hum.2016.071. Review.

26.

GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly.

Welker JM, Wierson WA, Wang Y, Poshusta TL, McNulty MS, Tisdale EE, Solin SL, Ekker SC, Clark KJ, McGrail M, Essner JJ.

Hum Gene Ther. 2016 Jun;27(6):423-4. doi: 10.1089/hum.2016.012. Epub 2016 May 6. No abstract available.

27.

Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer.

Zhao Y, Wang L, Ren S, Wang L, Blackburn PR, McNulty MS, Gao X, Qiao M, Vessella RL, Kohli M, Zhang J, Karnes RJ, Tindall DJ, Kim Y, MacLeod R, Ekker SC, Kang T, Sun Y, Huang H.

Cell Rep. 2016 Apr 19;15(3):599-610. doi: 10.1016/j.celrep.2016.03.038. Epub 2016 Apr 7.

28.

Active recombinant Tol2 transposase for gene transfer and gene discovery applications.

Ni J, Wangensteen KJ, Nelsen D, Balciunas D, Skuster KJ, Urban MD, Ekker SC.

Mob DNA. 2016 Mar 31;7:6. doi: 10.1186/s13100-016-0062-z. eCollection 2016.

29.

Mayo Clinic Zebrafish Facility Overview.

Leveque RE, Clark KJ, Ekker SC.

Zebrafish. 2016 Jul;13 Suppl 1:S44-6. doi: 10.1089/zeb.2015.1227. Epub 2016 Mar 29.

30.

FusX: A Rapid One-Step Transcription Activator-Like Effector Assembly System for Genome Science.

Ma AC, McNulty MS, Poshusta TL, Campbell JM, Martínez-Gálvez G, Argue DP, Lee HB, Urban MD, Bullard CE, Blackburn PR, Man TK, Clark KJ, Ekker SC.

Hum Gene Ther. 2016 Jun;27(6):451-63. doi: 10.1089/hum.2015.172. Epub 2016 Mar 15.

31.

Students being and becoming scientists: measured success in a novel science education partnership.

Yang J, LaBounty TJ, Ekker SC, Pierret C.

Palgrave Commun. 2016;2. pii: 16005. doi: 10.1057/palcomms.2016.5. Epub 2016 Mar 1.

32.

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells.

Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D.

J Cell Sci. 2015 Oct 1;128(19):3556-68. doi: 10.1242/jcs.167601. Epub 2015 Jul 1. Erratum in: J Cell Sci. 2018 Mar 16;131(6):.

33.

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis.

Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC.

PLoS One. 2015 Jun 25;10(6):e0130688. doi: 10.1371/journal.pone.0130688. eCollection 2015.

34.

Etv2 and fli1b function together as key regulators of vasculogenesis and angiogenesis.

Craig MP, Grajevskaja V, Liao HK, Balciuniene J, Ekker SC, Park JS, Essner JJ, Balciunas D, Sumanas S.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):865-76. doi: 10.1161/ATVBAHA.114.304768. Epub 2015 Feb 26.

35.

Using engineered endonucleases to create knockout and knockin zebrafish models.

Bedell VM, Ekker SC.

Methods Mol Biol. 2015;1239:291-305. doi: 10.1007/978-1-4939-1862-1_17.

36.

Making designer mutants in model organisms.

Peng Y, Clark KJ, Campbell JM, Panetta MR, Guo Y, Ekker SC.

Development. 2014 Nov;141(21):4042-54. doi: 10.1242/dev.102186. Review.

37.

In vivo orientation of single myosin lever arms in zebrafish skeletal muscle.

Sun X, Ekker SC, Shelden EA, Takubo N, Wang Y, Burghardt TP.

Biophys J. 2014 Sep 16;107(6):1403-14. doi: 10.1016/j.bpj.2014.07.055.

38.

TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism.

Fadel HJ, Morrison JH, Saenz DT, Fuchs JR, Kvaratskhelia M, Ekker SC, Poeschla EM.

J Virol. 2014 Sep 1;88(17):9704-17. doi: 10.1128/JVI.01397-14. Epub 2014 Jun 18.

39.

Influenza knowledge, attitude, and behavior survey for grade school students: design and novel assessment methodology.

Koep TH, Huskins WC, Clemens C, Jenkins S, Pierret C, Ekker SC, Enders FT.

J Community Health. 2014 Dec;39(6):1231-40. doi: 10.1007/s10900-014-9884-0.

40.

TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells.

Wu X, Blackburn PR, Tschumper RC, Ekker SC, Jelinek DF.

Blood Cancer J. 2014 May 9;4:e210. doi: 10.1038/bcj.2014.32.

41.

Larval zebrafish model for FDA-approved drug repositioning for tobacco dependence treatment.

Cousin MA, Ebbert JO, Wiinamaki AR, Urban MD, Argue DP, Ekker SC, Klee EW.

PLoS One. 2014 Mar 21;9(3):e90467. doi: 10.1371/journal.pone.0090467. eCollection 2014.

42.

Detection of 1α,25-dihydroxyvitamin D-regulated miRNAs in zebrafish by whole transcriptome sequencing.

Craig TA, Zhang Y, Magis AT, Funk CC, Price ND, Ekker SC, Kumar R.

Zebrafish. 2014 Jun;11(3):207-18. doi: 10.1089/zeb.2013.0899. Epub 2014 Mar 20.

43.

Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia.

He BL, Shi X, Man CH, Ma AC, Ekker SC, Chow HC, So CW, Choi WW, Zhang W, Zhang Y, Leung AY.

Blood. 2014 Apr 17;123(16):2518-29. doi: 10.1182/blood-2013-02-486688. Epub 2014 Mar 3.

44.

The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation.

Singh M, Bhartiya D, Maini J, Sharma M, Singh AR, Kadarkaraisamy S, Rana R, Sabharwal A, Nanda S, Ramachandran A, Mittal A, Kapoor S, Sehgal P, Asad Z, Kaushik K, Vellarikkal SK, Jagga D, Muthuswami M, Chauhan RK, Leonard E, Priyadarshini R, Halimani M, Malhotra S, Patowary A, Vishwakarma H, Joshi P, Bhardwaj V, Bhaumik A, Bhatt B, Jha A, Kumar A, Budakoti P, Lalwani MK, Meli R, Jalali S, Joshi K, Pal K, Dhiman H, Laddha SV, Jadhav V, Singh N, Pandey V, Sachidanandan C, Ekker SC, Klee EW, Scaria V, Sivasubbu S.

Database (Oxford). 2014 Feb 26;2014:bau011. doi: 10.1093/database/bau011. Print 2014.

45.

New and TALENted genome engineering toolbox.

Campbell JM, Hartjes KA, Nelson TJ, Xu X, Ekker SC.

Circ Res. 2013 Aug 16;113(5):571-87. doi: 10.1161/CIRCRESAHA.113.301765. Review.

46.

High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design.

Ma AC, Lee HB, Clark KJ, Ekker SC.

PLoS One. 2013 May 29;8(5):e65259. doi: 10.1371/journal.pone.0065259. Print 2013.

47.

The zebrafish as a model to study polycystic liver disease.

Tietz Bogert PS, Huang BQ, Gradilone SA, Masyuk TV, Moulder GL, Ekker SC, Larusso NF.

Zebrafish. 2013 Jun;10(2):211-7. doi: 10.1089/zeb.2012.0825. Epub 2013 May 13.

48.

A sequence-based variation map of zebrafish.

Patowary A, Purkanti R, Singh M, Chauhan R, Singh AR, Swarnkar M, Singh N, Pandey V, Torroja C, Clark MD, Kocher JP, Clark KJ, Stemple DL, Klee EW, Ekker SC, Scaria V, Sivasubbu S.

Zebrafish. 2013 Mar;10(1):15-20. doi: 10.1089/zeb.2012.0848.

49.

The CRISPR system--keeping zebrafish gene targeting fresh.

Blackburn PR, Campbell JM, Clark KJ, Ekker SC.

Zebrafish. 2013 Mar;10(1):116-8. doi: 10.1089/zeb.2013.9999. Epub 2013 Mar 28. Review.

50.

Primary neuron culture for nerve growth and axon guidance studies in zebrafish (Danio rerio).

Chen Z, Lee H, Henle SJ, Cheever TR, Ekker SC, Henley JR.

PLoS One. 2013;8(3):e57539. doi: 10.1371/journal.pone.0057539. Epub 2013 Mar 4.

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