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Items: 1 to 50 of 126

1.

Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics.

Mohebnasab M, Eriksson O, Persson B, Sandholm K, Mohlin C, Huber-Lang M, Keating BJ, Ekdahl KN, Nilsson B.

Front Immunol. 2019 Nov 8;10:2539. doi: 10.3389/fimmu.2019.02539. eCollection 2019. Review.

2.

Celiac disease and complement activation in response to Streptococcus pneumoniae.

Tjernberg AR, Woksepp H, Sandholm K, Johansson M, Dahle C, Ludvigsson JF, Bonnedahl J, Nilsson P, Ekdahl KN.

Eur J Pediatr. 2019 Nov 5. doi: 10.1007/s00431-019-03490-w. [Epub ahead of print]

PMID:
31691001
3.

Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals.

Sandholm K, Carlsson H, Persson B, Skattum L, Tjernberg I, Nilsson B, Ekdahl KN.

Scand J Immunol. 2019 Sep 19:e12831. doi: 10.1111/sji.12831. [Epub ahead of print] No abstract available.

PMID:
31536648
4.

Is generation of C3(H2O) necessary for activation of the alternative pathway in real life?

Ekdahl KN, Mohlin C, Adler A, Åman A, Manivel VA, Sandholm K, Huber-Lang M, Fromell K, Nilsson B.

Mol Immunol. 2019 Oct;114:353-361. doi: 10.1016/j.molimm.2019.07.032. Epub 2019 Aug 22. Review.

5.

The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System.

Eriksson O, Mohlin C, Nilsson B, Ekdahl KN.

Front Immunol. 2019 Jul 10;10:1590. doi: 10.3389/fimmu.2019.01590. eCollection 2019. Review.

6.

A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity.

Ekdahl KN, Fromell K, Mohlin C, Teramura Y, Nilsson B.

Sci Technol Adv Mater. 2019 Jun 24;20(1):688-698. doi: 10.1080/14686996.2019.1625721. eCollection 2019. Review.

7.

C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases.

Zhao F, Afonso S, Lindner S, Hartmann A, Löschmann I, Nilsson B, Ekdahl KN, Weber LT, Habbig S, Schalk G, Kirschfink M, Zipfel PF, Skerka C.

Front Immunol. 2019 May 31;10:1030. doi: 10.3389/fimmu.2019.01030. eCollection 2019.

8.

Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium.

Noiri M, Asawa K, Okada N, Kodama T, Murayama Y, Inoue Y, Ishihara K, Ekdahl KN, Nilsson B, Teramura Y.

J Biomed Mater Res A. 2019 Aug;107(8):1779-1792. doi: 10.1002/jbm.a.36697. Epub 2019 Apr 26.

PMID:
30983125
9.

Exposure of von Willebrand Factor on Isolated Hepatocytes Promotes Tethering of Platelets to the Cell Surface.

Gustafson E, Hamad OA, Deckmyn H, Barbu A, Ekdahl KN, Nilsson B.

Transplantation. 2019 Aug;103(8):1630-1638. doi: 10.1097/TP.0000000000002707.

PMID:
30896677
10.

Validation of an MPC Polymer Coating to Attenuate Surface-Induced Crosstalk between the Complement and Coagulation Systems in Whole Blood in In Vitro and In Vivo Models.

Asif S, Asawa K, Inoue Y, Ishihara K, Lindell B, Holmgren R, Nilsson B, Rydén A, Jensen-Waern M, Teramura Y, Ekdahl KN.

Macromol Biosci. 2019 May;19(5):e1800485. doi: 10.1002/mabi.201800485. Epub 2019 Feb 20.

PMID:
30786149
11.

Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use.

Sandholm K, Persson B, Skattum L, Eggertsen G, Nyman D, Gunnarsson I, Svenungson E, Nilsson B, Ekdahl KN.

Front Immunol. 2019 Jan 25;10:7. doi: 10.3389/fimmu.2019.00007. eCollection 2019.

12.

Interpretation of Serological Complement Biomarkers in Disease.

Ekdahl KN, Persson B, Mohlin C, Sandholm K, Skattum L, Nilsson B.

Front Immunol. 2018 Oct 24;9:2237. doi: 10.3389/fimmu.2018.02237. eCollection 2018. Review.

13.

The multifaceted role of complement in kidney transplantation.

Biglarnia AR, Huber-Lang M, Mohlin C, Ekdahl KN, Nilsson B.

Nat Rev Nephrol. 2018 Dec;14(12):767-781. doi: 10.1038/s41581-018-0071-x. Review.

PMID:
30367174
14.

Development and evaluation of cationic amphiphilic antimicrobial 2,5-diketopiperazines.

Labrière C, Kondori N, Caous JS, Boomgaren M, Sandholm K, Ekdahl KN, Hansen JH, Svenson J.

J Pept Sci. 2018 Jul;24(7):e3090. doi: 10.1002/psc.3090. Epub 2018 May 29. No abstract available.

PMID:
29845683
15.

Author Correction: Dispersion of TiO2 nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins.

Seisenbaeva GA, Fromell K, Vinogradov VV, Terekhov AN, Pakhomov AV, Nilsson B, Ekdahl KN, Vinogradov VV, Kessler VG.

Sci Rep. 2018 Mar 8;8(1):4416. doi: 10.1038/s41598-018-22717-8.

16.

A model to study complement involvement in experimental retinal degeneration.

Mohlin C, Sandholm K, Kvanta A, Ekdahl KN, Johansson K.

Ups J Med Sci. 2018 Mar;123(1):28-42. doi: 10.1080/03009734.2018.1431744. Epub 2018 Feb 13.

17.

Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles.

Ekdahl KN, Davoodpour P, Ekstrand-Hammarström B, Fromell K, Hamad OA, Hong J, Bucht A, Mohlin C, Seisenbaeva GA, Kessler VG, Nilsson B.

Nanomedicine. 2018 Apr;14(3):735-744. doi: 10.1016/j.nano.2017.12.008. Epub 2017 Dec 24.

PMID:
29277639
18.

Dispersion of TiO2 nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins.

Seisenbaeva GA, Fromell K, Vinogradov VV, Terekhov AN, Pakhomov AV, Nilsson B, Ekdahl KN, Vinogradov VV, Kessler VG.

Sci Rep. 2017 Nov 13;7(1):15448. doi: 10.1038/s41598-017-15792-w. Erratum in: Sci Rep. 2018 Mar 8;8(1):4416.

19.

Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions.

Huber-Lang M, Ekdahl KN, Wiegner R, Fromell K, Nilsson B.

Semin Immunopathol. 2018 Jan;40(1):87-102. doi: 10.1007/s00281-017-0646-9. Epub 2017 Sep 12. Review.

20.

The link between morphology and complement in ocular disease.

Mohlin C, Sandholm K, Ekdahl KN, Nilsson B.

Mol Immunol. 2017 Sep;89:84-99. doi: 10.1016/j.molimm.2017.05.028. Epub 2017 Jun 15. Review.

PMID:
28622910
21.

Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Ekdahl KN, Soveri I, Hilborn J, Fellström B, Nilsson B.

Nat Rev Nephrol. 2017 May;13(5):285-296. doi: 10.1038/nrneph.2017.17. Epub 2017 Feb 27. Review.

PMID:
28239169
22.

Cell Adhesion Induced Using Surface Modification with Cell-Penetrating Peptide-Conjugated Poly(ethylene glycol)-Lipid: A New Cell Glue for 3D Cell-Based Structures.

Teramura Y, Asif S, Ekdahl KN, Gustafson E, Nilsson B.

ACS Appl Mater Interfaces. 2017 Jan 11;9(1):244-254. doi: 10.1021/acsami.6b14584. Epub 2016 Dec 23.

PMID:
27976850
23.

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation.

Ekdahl KN, Teramura Y, Hamad OA, Asif S, Duehrkop C, Fromell K, Gustafson E, Hong J, Kozarcanin H, Magnusson PU, Huber-Lang M, Garred P, Nilsson B.

Immunol Rev. 2016 Nov;274(1):245-269. doi: 10.1111/imr.12471. Review.

PMID:
27782319
24.

Control of IBMIR Induced by Fresh and Cryopreserved Hepatocytes by Low Molecular Weight Dextran Sulfate Versus Heparin.

Gustafson E, Asif S, Kozarcanin H, Elgue G, Meurling S, Ekdahl KN, Nilsson B.

Cell Transplant. 2017 Jan 24;26(1):71-81. doi: 10.3727/096368916X692609. Epub 2016 Jul 22.

25.

Complement inhibition in biomaterial- and biosurface-induced thromboinflammation.

Ekdahl KN, Huang S, Nilsson B, Teramura Y.

Semin Immunol. 2016 Jun;28(3):268-77. doi: 10.1016/j.smim.2016.04.006. Epub 2016 May 17. Review.

PMID:
27211838
26.

Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function.

Lindblom RP, Aeinehband S, Ström M, Al Nimer F, Sandholm K, Khademi M, Nilsson B, Piehl F, Ekdahl KN.

Clin Immunol. 2016 May;166-167:89-95. doi: 10.1016/j.clim.2016.04.003. Epub 2016 Apr 13.

27.

Evidence of contact activation in patients suffering from ST-elevation myocardial infarction.

Christensen K, Kozarcanin H, Ekdahl KN, Nilsson B.

Thromb Res. 2016 May;141:158-62. doi: 10.1016/j.thromres.2016.03.020. Epub 2016 Mar 18.

PMID:
27058272
28.

A hybrid of cells and pancreatic islets toward a new bioartificial pancreas.

Teramura Y, Ekdahl KN, Barbu A.

Regen Ther. 2016 Mar 19;3:68-74. doi: 10.1016/j.reth.2016.03.004. eCollection 2016 Mar. Review.

29.

Development and characterization of an innovative heparin coating to stabilize and protect liposomes against adverse immune reactions.

Duehrkop C, Leneweit G, Heyder C, Fromell K, Edwards K, Ekdahl KN, Nilsson B.

Colloids Surf B Biointerfaces. 2016 May 1;141:576-583. doi: 10.1016/j.colsurfb.2016.02.014. Epub 2016 Feb 8.

PMID:
26897551
30.

Heparinization of cell surfaces with short peptide-conjugated PEG-lipid regulates thromboinflammation in transplantation of human MSCs and hepatocytes.

Asif S, Ekdahl KN, Fromell K, Gustafson E, Barbu A, Le Blanc K, Nilsson B, Teramura Y.

Acta Biomater. 2016 Apr 15;35:194-205. doi: 10.1016/j.actbio.2016.02.018. Epub 2016 Feb 12.

PMID:
26876877
31.

The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.

Kozarcanin H, Lood C, Munthe-Fog L, Sandholm K, Hamad OA, Bengtsson AA, Skjoedt MO, Huber-Lang M, Garred P, Ekdahl KN, Nilsson B.

J Thromb Haemost. 2016 Mar;14(3):531-45. doi: 10.1111/jth.13208. Epub 2016 Feb 15.

32.

Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood.

Huang S, Engberg AE, Jonsson N, Sandholm K, Nicholls IA, Mollnes TE, Fromell K, Nilsson B, Ekdahl KN.

Biomaterials. 2016 Jan;77:111-9. doi: 10.1016/j.biomaterials.2015.10.067. Epub 2015 Nov 9.

PMID:
26584351
33.

Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response.

Lindblom RP, Berg A, Ström M, Aeinehband S, Dominguez CA, Al Nimer F, Abdelmagid N, Heinig M, Zelano J, Harnesk K, Hübner N, Nilsson B, Ekdahl KN, Diez M, Cullheim S, Piehl F.

J Neuroinflammation. 2015 Oct 26;12:192. doi: 10.1186/s12974-015-0413-6.

34.

Complement Interception Across Humoral Incompatibility in Solid Organ Transplantation: A Clinical Perspective.

Biglarnia AR, Ekdahl KN, Nilsson B.

Adv Exp Med Biol. 2015;865:211-33. doi: 10.1007/978-3-319-18603-0_13. Review.

PMID:
26306452
35.

Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy.

Teramura Y, Asif S, Ekdahl KN, Nilsson B.

Adv Exp Med Biol. 2015;865:189-209. doi: 10.1007/978-3-319-18603-0_12. Review.

PMID:
26306451
36.

Thromboinflammation in Therapeutic Medicine.

Ekdahl KN, Teramura Y, Asif S, Jonsson N, Magnusson PU, Nilsson B.

Adv Exp Med Biol. 2015;865:3-17. doi: 10.1007/978-3-319-18603-0_1. Review.

PMID:
26306440
37.

Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18.

Hamad OA, Mitroulis I, Fromell K, Kozarcanin H, Chavakis T, Ricklin D, Lambris JD, Ekdahl KN, Nilsson B.

Thromb Haemost. 2015 Nov 25;114(6):1207-17. doi: 10.1160/TH15-02-0162. Epub 2015 Aug 13.

38.

Heparin molecularly imprinted surfaces for the attenuation of complement activation in blood.

Rosengren-Holmberg JP, Andersson J, Smith JR, Alexander C, Alexander MR, Tovar G, Ekdahl KN, Nicholls IA.

Biomater Sci. 2015 Aug;3(8):1208-17. doi: 10.1039/c5bm00047e. Epub 2015 Jun 10.

PMID:
26222036
39.

Low affinity binding of plasma proteins to lipid-coated quantum dots as observed by in situ fluorescence correlation spectroscopy.

Klapper Y, Maffre P, Shang L, Ekdahl KN, Nilsson B, Hettler S, Dries M, Gerthsen D, Nienhaus GU.

Nanoscale. 2015 Jun 14;7(22):9980-4. doi: 10.1039/c5nr01694k. Epub 2015 May 15.

PMID:
25975280
40.

Preface. 15th European Meeting on Complement in Human Disease 2015, Uppsala, Sweden.

Nilsson B, Ekdahl KN, Kemper C, Mollnes TE.

Mol Immunol. 2015 Sep;67(1):1-2. doi: 10.1016/j.molimm.2015.04.006. Epub 2015 Apr 29. No abstract available.

PMID:
25934434
41.

Complement and platelets: Mutual interference in the immune network.

Speth C, Rambach G, Würzner R, Lass-Flörl C, Kozarcanin H, Hamad OA, Nilsson B, Ekdahl KN.

Mol Immunol. 2015 Sep;67(1):108-18. doi: 10.1016/j.molimm.2015.03.244. Epub 2015 Apr 14. Review.

PMID:
25886718
42.

Complement component C3 and butyrylcholinesterase activity are associated with neurodegeneration and clinical disability in multiple sclerosis.

Aeinehband S, Lindblom RP, Al Nimer F, Vijayaraghavan S, Sandholm K, Khademi M, Olsson T, Nilsson B, Ekdahl KN, Darreh-Shori T, Piehl F.

PLoS One. 2015 Apr 2;10(4):e0122048. doi: 10.1371/journal.pone.0122048. eCollection 2015.

43.

TiO2 nanoparticles tested in a novel screening whole human blood model of toxicity trigger adverse activation of the kallikrein system at low concentrations.

Ekstrand-Hammarström B, Hong J, Davoodpour P, Sandholm K, Ekdahl KN, Bucht A, Nilsson B.

Biomaterials. 2015 May;51:58-68. doi: 10.1016/j.biomaterials.2015.01.031. Epub 2015 Feb 17.

PMID:
25770998
44.

The role of complement factor C3 in lipid metabolism.

Barbu A, Hamad OA, Lind L, Ekdahl KN, Nilsson B.

Mol Immunol. 2015 Sep;67(1):101-7. doi: 10.1016/j.molimm.2015.02.027. Epub 2015 Mar 6. Review.

PMID:
25746915
45.

Low concentrations of citrate reduce complement and granulocyte activation in vitro in human blood.

Huang S, Sandholm K, Jonsson N, Nilsson A, Wieslander A, Grundström G, Hancock V, Ekdahl KN.

Clin Kidney J. 2015 Feb;8(1):31-7. doi: 10.1093/ckj/sfu127. Epub 2014 Dec 1.

46.

Rare loss-of-function mutation in complement component C3 provides insight into molecular and pathophysiological determinants of complement activity.

Sfyroera G, Ricklin D, Reis ES, Chen H, Wu EL, Kaznessis YN, Ekdahl KN, Nilsson B, Lambris JD.

J Immunol. 2015 Apr 1;194(7):3305-16. doi: 10.4049/jimmunol.1402781. Epub 2015 Feb 23.

47.

Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma.

Engberg AE, Nilsson PH, Huang S, Fromell K, Hamad OA, Mollnes TE, Rosengren-Holmberg JP, Sandholm K, Teramura Y, Nicholls IA, Nilsson B, Ekdahl KN.

Biomaterials. 2015 Jan;36:55-65. doi: 10.1016/j.biomaterials.2014.09.011. Epub 2014 Oct 5.

PMID:
25292422
48.

Early cytokine release in response to live Borrelia burgdorferi Sensu Lato Spirochetes is largely complement independent.

Sandholm K, Henningsson AJ, Säve S, Bergström S, Forsberg P, Jonsson N, Ernerudh J, Ekdahl KN.

PLoS One. 2014 Sep 29;9(9):e108013. doi: 10.1371/journal.pone.0108013. eCollection 2014.

49.

The role and regulation of complement activation as part of the thromboinflammation elicited in cell therapies.

Nilsson B, Teramura Y, Ekdahl KN.

Mol Immunol. 2014 Oct;61(2):185-90. doi: 10.1016/j.molimm.2014.06.009. Epub 2014 Jul 3. Review.

PMID:
24998801
50.

Influence of persistent organic pollutants on the complement system in a population-based human sample.

Kumar J, Lind PM, Salihovic S, van Bavel B, Ekdahl KN, Nilsson B, Lind L, Ingelsson E.

Environ Int. 2014 Oct;71:94-100. doi: 10.1016/j.envint.2014.06.009. Epub 2014 Jul 2.

PMID:
24996157

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