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Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes.

Elyahu Y, Hekselman I, Eizenberg-Magar I, Berner O, Strominger I, Schiller M, Mittal K, Nemirovsky A, Eremenko E, Vital A, Simonovsky E, Chalifa-Caspi V, Friedman N, Yeger-Lotem E, Monsonego A.

Sci Adv. 2019 Aug 21;5(8):eaaw8330. doi: 10.1126/sciadv.aaw8330. eCollection 2019 Aug.


Diverse continuum of CD4+ T-cell states is determined by hierarchical additive integration of cytokine signals.

Eizenberg-Magar I, Rimer J, Zaretsky I, Lara-Astiaso D, Reich-Zeliger S, Friedman N.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6447-E6456. doi: 10.1073/pnas.1615590114. Epub 2017 Jul 17.

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