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Playing a long game.
Eisenstein M.
Nat Methods. 2019 Aug;16(8):683-686. doi: 10.1038/s41592-019-0507-7. No abstract available.
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Biosimilars: mimicking biological drugs.
Nature. 2019 May;569(7755):S1. doi: 10.1038/d41586-019-01400-6. No abstract available.
Bring on the biosimilars.
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Nat Biotechnol. 2019 Apr 5. doi: 10.1038/d41587-019-00011-w. [Epub ahead of print] No abstract available.
High-Fidelity Nanopore Sequencing of Ultra-Short DNA Targets.
Wilson BD, Eisenstein M, Soh HT.
Anal Chem. 2019 May 21;91(10):6783-6789. doi: 10.1021/acs.analchem.9b00856. Epub 2019 May 10.
Cellular censuses to guide cancer care.
Nature. 2019 Mar;567(7749):555-557. doi: 10.1038/d41586-019-00904-5. No abstract available.
Building an annotated ark.
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Tea's value as a cancer therapy is steeped in uncertainty.
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Illumina swallows PacBio in long shot for market domination.
Nat Biotechnol. 2019 Jan 3;37(1):3-4. doi: 10.1038/nbt0119-3. No abstract available.
On their best behavior.
Nat Methods. 2019 Jan;16(1):5-8. doi: 10.1038/s41592-018-0277-7. No abstract available.
Shape-based separation of synthetic microparticles.
Mage PL, Csordas AT, Brown T, Klinger D, Eisenstein M, Mitragotri S, Hawker C, Soh HT.
Nat Mater. 2019 Jan;18(1):82-89. doi: 10.1038/s41563-018-0244-9. Epub 2018 Dec 10.
Direct Selection Strategy for Isolating Aptamers with pH-Sensitive Binding Activity.
Gordon CKL, Eisenstein M, Soh HT.
ACS Sens. 2018 Dec 28;3(12):2574-2580. doi: 10.1021/acssensors.8b00945. Epub 2018 Dec 6.
Transparent tissues bring cells into focus for microscopy.
Nature. 2018 Dec;564(7734):147-149. doi: 10.1038/d41586-018-07593-6. No abstract available.
Lymphoma: 4 big questions.
Nature. 2018 Nov;563(7731):S55. doi: 10.1038/d41586-018-07367-0. No abstract available.
The cost of surviving cancer.
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Ulcerative colitis: towards remission.
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Gut reaction.
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An inner light.
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The clinical code-breakers.
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Immunotherapy offers a promising bet against brain cancer.
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A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation.
Nuta GC, Gilad Y, Gershoni M, Sznajderman A, Schlesinger T, Bialik S, Eisenstein M, Pietrokovski S, Kimchi A.
Autophagy. 2019 Mar;15(3):438-452. doi: 10.1080/15548627.2018.1525476. Epub 2018 Oct 8.
Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis.
Blank M, Bashi T, Lachnish J, Ben-Ami-Shor D, Shovman O, Fridkin M, Eisenstein M, Volkov A, Barshack I, Shoenfeld Y.
PLoS One. 2018 Aug 8;13(8):e0200615. doi: 10.1371/journal.pone.0200615. eCollection 2018.
Drug designers embrace cryo-EM.
Nat Biotechnol. 2018 Jul 6;36(7):557-558. doi: 10.1038/nbt0718-557. No abstract available.
CRISPR takes on Huntington's disease.
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Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy.
Shiloh R, Gilad Y, Ber Y, Eisenstein M, Aweida D, Bialik S, Cohen S, Kimchi A.
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Microbiology: making the best of PCR bias.
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Bat research takes wing.
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Infection forecasts powered by big data.
Nature. 2018 Mar 8;555(7695):S2-S4. doi: 10.1038/d41586-018-02473-5. No abstract available.
Direct Selection of Fluorescence-Enhancing RNA Aptamers.
Gotrik M, Sekhon G, Saurabh S, Nakamoto M, Eisenstein M, Soh HT.
J Am Chem Soc. 2018 Mar 14;140(10):3583-3591. doi: 10.1021/jacs.7b10724. Epub 2018 Mar 5.
Strategy for Generating Sequence-Defined Aptamer Reagent Sets for Detecting Protein Contaminants in Biotherapeutics.
McGivney JB 4th, Csordas AT, Walker FM, Bagley ER, Gruber EM, Mage PL, Casas-Finet J, Nakamoto MA, Eisenstein M, Larkin CJ, Strouse RJ, Soh HT.
Anal Chem. 2018 Mar 6;90(5):3262-3269. doi: 10.1021/acs.analchem.7b04775. Epub 2018 Feb 13.
Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Chorev DS, Volberg T, Livne A, Eisenstein M, Martins B, Kam Z, Jockusch BM, Medalia O, Sharon M, Geiger B.
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An illuminating experience.
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Making cancer immunotherapy a surer bet.
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How social scientists can help to shape climate policy.
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Diagnostics: Missing the point.
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Therapeutics: Spoilt for choice.
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An ace in the hole for DNA sequencing.
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Dual-reporter SERS-based biomolecular assay with reduced false-positive signals.
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Improvement of the Bag-Mediated Filtration System for Sampling Wastewater and Wastewater-Impacted Waters.
Fagnant CS, Sánchez-Gonzalez LM, Zhou NA, Falman JC, Eisenstein M, Guelig D, Ockerman B, Guan Y, Kossik AL, Linden YS, Beck NK, Wilmouth R, Komen E, Mwangi B, Nyangao J, Shirai JH, Novosselov I, Borus P, Boyle DS, Meschke JS.
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Mechanobiology: A measure of molecular muscle.
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Pursuing the simple life.
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Biology: A slow-motion epidemic.
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Regulation: Rewriting the regenerative rulebook.
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A unique type of GSK-3 inhibitor brings new opportunities to the clinic.
Licht-Murava A, Paz R, Vaks L, Avrahami L, Plotkin B, Eisenstein M, Eldar-Finkelman H.
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High-Throughput Discovery of Aptamers for Sandwich Assays.
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Electrotherapy: Shock value.
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