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Items: 1 to 50 of 177

1.

Distinct gene-selective roles for a network of core promoter factors in Drosophila neural stem cell identity.

Neves A, Eisenman RN.

Biol Open. 2019 Apr 4;8(4). pii: bio042168. doi: 10.1242/bio.042168.

2.

Condensin-Dependent Chromatin Compaction Represses Transcription Globally during Quiescence.

Swygert SG, Kim S, Wu X, Fu T, Hsieh TH, Rando OJ, Eisenman RN, Shendure J, McKnight JN, Tsukiyama T.

Mol Cell. 2019 Feb 7;73(3):533-546.e4. doi: 10.1016/j.molcel.2018.11.020. Epub 2018 Dec 27.

PMID:
30595435
3.

The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis.

Carroll PA, Freie BW, Mathsyaraja H, Eisenman RN.

Front Med. 2018 Aug;12(4):412-425. doi: 10.1007/s11684-018-0650-z. Epub 2018 Jul 27. Review.

PMID:
30054853
4.

Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis.

Poudel KR, Roh-Johnson M, Su A, Ho T, Mathsyaraja H, Anderson S, Grady WM, Moens CB, Conacci-Sorrell M, Eisenman RN, Bai J.

Dev Cell. 2018 Jun 18;45(6):738-752.e6. doi: 10.1016/j.devcel.2018.05.021.

5.

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.

Schaub FX, Dhankani V, Berger AC, Trivedi M, Richardson AB, Shaw R, Zhao W, Zhang X, Ventura A, Liu Y, Ayer DE, Hurlin PJ, Cherniack AD, Eisenman RN, Bernard B, Grandori C; Cancer Genome Atlas Network.

Cell Syst. 2018 Mar 28;6(3):282-300.e2. doi: 10.1016/j.cels.2018.03.003.

6.

Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal.

Kanatsu-Shinohara M, Tanaka T, Ogonuki N, Ogura A, Morimoto H, Cheng PF, Eisenman RN, Trumpp A, Shinohara T.

Genes Dev. 2016 Dec 1;30(23):2637-2648. doi: 10.1101/gad.287045.116.

7.

Quantitative Method to Investigate the Balance between Metabolism and Proteome Biomass: Starting from Glycine.

Gu H, Carroll PA, Du J, Zhu J, Neto FC, Eisenman RN, Raftery D.

Angew Chem Int Ed Engl. 2016 Dec 12;55(50):15646-15650. doi: 10.1002/anie.201609236. Epub 2016 Nov 15.

8.

MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation.

Anderson S, Poudel KR, Roh-Johnson M, Brabletz T, Yu M, Borenstein-Auerbach N, Grady WN, Bai J, Moens CB, Eisenman RN, Conacci-Sorrell M.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5481-90. doi: 10.1073/pnas.1610994113. Epub 2016 Aug 26.

9.

Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.

Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D.

Genes Dev. 2016 Jun 1;30(11):1289-99. doi: 10.1101/gad.279307.116.

10.

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause.

Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura S, Reyes A, Prendergast ÁM, Baumgärtner D, Carnevalli LS, Atzberger A, Haas S, von Paleske L, Boroviak T, Wörsdörfer P, Essers MA, Kloz U, Eisenman RN, Edenhofer F, Bertone P, Huber W, van der Hoeven F, Smith A, Trumpp A.

Cell. 2016 Feb 11;164(4):668-80. doi: 10.1016/j.cell.2015.12.033.

11.

Parsing Myc Paralogs in Oncogenesis.

Mathsyaraja H, Eisenman RN.

Cancer Cell. 2016 Jan 11;29(1):1-2. doi: 10.1016/j.ccell.2015.12.009.

12.

The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling.

Hunt LC, Xu B, Finkelstein D, Fan Y, Carroll PA, Cheng PF, Eisenman RN, Demontis F.

Genes Dev. 2015 Dec 1;29(23):2475-89. doi: 10.1101/gad.267419.115. Epub 2015 Nov 19.

13.

Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.

Hiler D, Chen X, Hazen J, Kupriyanov S, Carroll PA, Qu C, Xu B, Johnson D, Griffiths L, Frase S, Rodriguez AR, Martin G, Zhang J, Jeon J, Fan Y, Finkelstein D, Eisenman RN, Baldwin K, Dyer MA.

Cell Stem Cell. 2015 Jul 2;17(1):101-15. doi: 10.1016/j.stem.2015.05.015.

14.

Metabolomics method to comprehensively analyze amino acids in different domains.

Gu H, Du J, Carnevale Neto F, Carroll PA, Turner SJ, Chiorean EG, Eisenman RN, Raftery D.

Analyst. 2015 Apr 21;140(8):2726-34. doi: 10.1039/c4an02386b. Epub 2015 Feb 20.

15.

Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis.

Carroll PA, Diolaiti D, McFerrin L, Gu H, Djukovic D, Du J, Cheng PF, Anderson S, Ulrich M, Hurley JB, Raftery D, Ayer DE, Eisenman RN.

Cancer Cell. 2015 Feb 9;27(2):271-85. doi: 10.1016/j.ccell.2014.11.024. Epub 2015 Jan 29.

16.

Growing old with Myc.

Carroll PA, Eisenman RN.

Cell. 2015 Jan 29;160(3):365-6. doi: 10.1016/j.cell.2015.01.018.

17.

Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis.

Diolaiti D, McFerrin L, Carroll PA, Eisenman RN.

Biochim Biophys Acta. 2015 May;1849(5):484-500. doi: 10.1016/j.bbagrm.2014.05.016. Epub 2014 May 22. Review.

18.

Stress-induced cleavage of Myc promotes cancer cell survival.

Conacci-Sorrell M, Ngouenet C, Anderson S, Brabletz T, Eisenman RN.

Genes Dev. 2014 Apr 1;28(7):689-707. doi: 10.1101/gad.231894.113.

19.

An overview of MYC and its interactome.

Conacci-Sorrell M, McFerrin L, Eisenman RN.

Cold Spring Harb Perspect Med. 2014 Jan 1;4(1):a014357. doi: 10.1101/cshperspect.a014357. Review. Erratum in: Cold Spring Harb Perspect Med. 2014 Apr;4(4). doi:10.1101/cshperspect.a023325.

20.

The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth.

Li L, Anderson S, Secombe J, Eisenman RN.

Development. 2013 Dec;140(23):4776-87. doi: 10.1242/dev.096941. Epub 2013 Oct 30.

21.

Molecular Characteristics in MRI-Classified Group 1 Glioblastoma Multiforme.

Haskins WE, Zablotsky BL, Foret MR, Ihrie RA, Alvarez-Buylla A, Eisenman RN, Berger MS, Lin CH.

Front Oncol. 2013 Jul 11;3:182. doi: 10.3389/fonc.2013.00182. eCollection 2013.

22.

Dual regulation of Myc by Abl.

Sanchez-Arévalo Lobo VJ, Doni M, Verrecchia A, Sanulli S, Fagà G, Piontini A, Bianchi M, Conacci-Sorrell M, Mazzarol G, Peg V, Losa JH, Ronchi P, Ponzoni M, Eisenman RN, Doglioni C, Amati B.

Oncogene. 2013 Nov 7;32(45):5261-71. doi: 10.1038/onc.2012.621. Epub 2013 Jan 14.

23.
24.

Constitutive gray hair in mice induced by melanocyte-specific deletion of c-Myc.

Pshenichnaya I, Schouwey K, Armaro M, Larue L, Knoepfler PS, Eisenman RN, Trumpp A, Delmas V, Beermann F.

Pigment Cell Melanoma Res. 2012 May;25(3):312-25. doi: 10.1111/j.1755-148X.2012.00998.x.

25.

Premetazoan ancestry of the Myc-Max network.

Young SL, Diolaiti D, Conacci-Sorrell M, Ruiz-Trillo I, Eisenman RN, King N.

Mol Biol Evol. 2011 Oct;28(10):2961-71. doi: 10.1093/molbev/msr132. Epub 2011 May 13.

26.

N-myc controls proliferation, morphogenesis, and patterning of the inner ear.

Domínguez-Frutos E, López-Hernández I, Vendrell V, Neves J, Gallozzi M, Gutsche K, Quintana L, Sharpe J, Knoepfler PS, Eisenman RN, Trumpp A, Giráldez F, Schimmang T.

J Neurosci. 2011 May 11;31(19):7178-89. doi: 10.1523/JNEUROSCI.0785-11.2011.

27.

Post-translational control of Myc function during differentiation.

Conacci-Sorrell M, Eisenman RN.

Cell Cycle. 2011 Feb 15;10(4):604-10. Epub 2011 Feb 15.

28.

Essential functions of the histone demethylase lid.

Li L, Greer C, Eisenman RN, Secombe J.

PLoS Genet. 2010 Nov 24;6(11):e1001221. doi: 10.1371/journal.pgen.1001221.

29.

An Integrated Genetic-Genomic Approach for the Identification of Novel Cancer Loci in Mice Sensitized to c-Myc-Induced Apoptosis.

Mendrysa SM, Akagi K, Roayaei J, Lien WH, Copeland NG, Jenkins NA, Eisenman RN.

Genes Cancer. 2010 May;1(5):465-479.

30.

Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis.

Conerly ML, Teves SS, Diolaiti D, Ulrich M, Eisenman RN, Henikoff S.

Genome Res. 2010 Oct;20(10):1383-90. doi: 10.1101/gr.106542.110. Epub 2010 Aug 13.

31.

Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation.

Conacci-Sorrell M, Ngouenet C, Eisenman RN.

Cell. 2010 Aug 6;142(3):480-93. doi: 10.1016/j.cell.2010.06.037.

32.

Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc.

Lin CH, Lin C, Tanaka H, Fero ML, Eisenman RN.

PLoS One. 2009 Nov 13;4(11):e7839. doi: 10.1371/journal.pone.0007839.

33.

Myc-regulated microRNAs attenuate embryonic stem cell differentiation.

Lin CH, Jackson AL, Guo J, Linsley PS, Eisenman RN.

EMBO J. 2009 Oct 21;28(20):3157-70. doi: 10.1038/emboj.2009.254. Epub 2009 Sep 10.

34.

Ratcheting Myc.

Freie BW, Eisenman RN.

Cancer Cell. 2008 Dec 9;14(6):425-6. doi: 10.1016/j.ccr.2008.11.008.

35.

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.

Laurenti E, Varnum-Finney B, Wilson A, Ferrero I, Blanco-Bose WE, Ehninger A, Knoepfler PS, Cheng PF, MacDonald HR, Eisenman RN, Bernstein ID, Trumpp A.

Cell Stem Cell. 2008 Dec 4;3(6):611-24. doi: 10.1016/j.stem.2008.09.005.

36.

Myc's broad reach.

Eilers M, Eisenman RN.

Genes Dev. 2008 Oct 15;22(20):2755-66. doi: 10.1101/gad.1712408. Review.

37.

Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation.

Weber A, Marquardt J, Elzi D, Forster N, Starke S, Glaum A, Yamada D, Defossez PA, Delrow J, Eisenman RN, Christiansen H, Eilers M.

EMBO J. 2008 Jun 4;27(11):1563-74. doi: 10.1038/emboj.2008.85. Epub 2008 May 1.

38.

Drosophila growth and development in the absence of dMyc and dMnt.

Pierce SB, Yost C, Anderson SA, Flynn EM, Delrow J, Eisenman RN.

Dev Biol. 2008 Mar 15;315(2):303-16. doi: 10.1016/j.ydbio.2007.12.026. Epub 2007 Dec 27.

39.

N-myc coordinates retinal growth with eye size during mouse development.

Martins RA, Zindy F, Donovan S, Zhang J, Pounds S, Wey A, Knoepfler PS, Eisenman RN, Roussel MF, Dyer MA.

Genes Dev. 2008 Jan 15;22(2):179-93. doi: 10.1101/gad.1608008.

40.

Myc stimulates B lymphocyte differentiation and amplifies calcium signaling.

Habib T, Park H, Tsang M, de Alborán IM, Nicks A, Wilson L, Knoepfler PS, Andrews S, Rawlings DJ, Eisenman RN, Iritani BM.

J Cell Biol. 2007 Nov 19;179(4):717-31. Epub 2007 Nov 12.

41.

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

Orian A, Delrow JJ, Rosales Nieves AE, Abed M, Metzger D, Paroush Z, Eisenman RN, Parkhurst SM.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15771-6. Epub 2007 Sep 26.

42.

The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection.

Secombe J, Eisenman RN.

Cell Cycle. 2007 Jun 1;6(11):1324-8. Epub 2007 Jun 14. Review.

PMID:
17568193
43.

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth.

Secombe J, Li L, Carlos L, Eisenman RN.

Genes Dev. 2007 Mar 1;21(5):537-51. Epub 2007 Feb 20.

44.

N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.

Hatton BA, Knoepfler PS, Kenney AM, Rowitch DH, de Alborán IM, Olson JM, Eisenman RN.

Cancer Res. 2006 Sep 1;66(17):8655-61.

45.

Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors.

Orian A, Grewal SS, Knoepfler PS, Edgar BA, Parkhurst SM, Eisenman RN.

Cold Spring Harb Symp Quant Biol. 2005;70:299-307.

PMID:
16869766
46.

N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development.

Zindy F, Knoepfler PS, Xie S, Sherr CJ, Eisenman RN, Roussel MF.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11579-83. Epub 2006 Jul 24.

47.

Myc influences global chromatin structure.

Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, McMahon SB, Eisenman RN.

EMBO J. 2006 Jun 21;25(12):2723-34. Epub 2006 May 25.

48.

Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.

Shiio Y, Rose DW, Aur R, Donohoe S, Aebersold R, Eisenman RN.

Mol Cell Biol. 2006 Feb;26(4):1386-97.

49.

Tumor suppression and normal aging in mice with constitutively high p53 activity.

Mendrysa SM, O'Leary KA, McElwee MK, Michalowski J, Eisenman RN, Powell DA, Perry ME.

Genes Dev. 2006 Jan 1;20(1):16-21.

50.

Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4.

Shiio Y, Suh KS, Lee H, Yuspa SH, Eisenman RN, Aebersold R.

J Biol Chem. 2006 Feb 3;281(5):2750-6. Epub 2005 Nov 29.

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