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Hypothesis: amyotrophic lateral sclerosis and environmental pollutants.

Swash M, Eisen A.

Muscle Nerve. 2020 Mar 5. doi: 10.1002/mus.26855. [Epub ahead of print]


ALS Split Phenotypes - To what extent do they exist?

Henderson RD, Eisen A.

Clin Neurophysiol. 2020 Apr;131(4):847-849. doi: 10.1016/j.clinph.2019.12.417. Epub 2020 Jan 30. No abstract available.


A case of SAPHO syndrome with Staphylococcus saprophyticus and Cutibacterium acnes osteitis.

Waters M, Krajden S, Stein J, Elmaraghy A, Eisen A, Aziz Z.

Rheumatol Adv Pract. 2020 Feb 6;4(1):rkz051. doi: 10.1093/rap/rkz051. eCollection 2020. No abstract available.


Temporal trends of patients with acute coronary syndrome and multi-vessel coronary artery disease - from the ACSIS registry.

Shiyovich A, Shlomo N, Cohen T, Iakobishvili Z, Kornowski R, Eisen A.

Int J Cardiol. 2020 Apr 1;304:8-13. doi: 10.1016/j.ijcard.2020.01.040. Epub 2020 Jan 21.


Temporal Trends of the Management and Outcome of Patients With Myocardial Infarction According to the Risk for Recurrent Cardiovascular Events.

Grinberg T, Bental T, Hammer Y, Assali A, Vaknin-Assa H, Kornowski R, Eisen A.

Am J Med. 2020 Jan 23. pii: S0002-9343(20)30038-3. doi: 10.1016/j.amjmed.2019.12.027. [Epub ahead of print]


Temporal Trends Analysis of the Characteristics, Management, and Outcomes of Women With Acute Coronary Syndrome (ACS): ACS Israeli Survey Registry 2000-2016.

Porter A, Paradkar A, Goldenberg I, Shlomo N, Cohen T, Kornowski R, Eisen A.

J Am Heart Assoc. 2020 Jan 7;9(1):e014721. doi: 10.1161/JAHA.119.014721. Epub 2019 Dec 19.


Effectiveness of the Genomics ADvISER decision aid for the selection of secondary findings from genomic sequencing: a randomized clinical trial.

Bombard Y, Clausen M, Shickh S, Mighton C, Casalino S, Kim THM, Muir SM, Carlsson L, Baxter N, Scheer A, Elser C, Eisen A, Panchal S, Graham T, Aronson M, Piccinin C, Mancuso T, Semotiuk K, Evans M, Carroll JC, Offit K, Robson M, Hamilton JG, Glogowski E, Schrader K, Kim RH, Lerner-Ellis J, Thorpe KE, Laupacis A; Incidental Genomics Study Team.

Genet Med. 2019 Dec 11. doi: 10.1038/s41436-019-0702-z. [Epub ahead of print]


Teschovirus and other swine and human enteric viruses in Brazilian watersheds impacted by swine husbandry.

Souza FG, Gularte JS, Demoliner M, Lima AF, Siebert JC, Rigotto C, Henzel A, Eisen AKA, Spilki FR.

Braz J Microbiol. 2019 Nov 30. doi: 10.1007/s42770-019-00197-w. [Epub ahead of print]


Soil contamination of a public park by human and canine mastadenovirus, as well as hookworms and Toxocara spp eggs.

Eisen AKA, Demoliner M, Oliveira KG, Troian EA, Mallmann L, Filippi M, Almeida PR, Spilki FR.

Rev Inst Med Trop Sao Paulo. 2019 Nov 25;61:e60. doi: 10.1590/S1678-9946201961060. eCollection 2019.


Cost-utility analysis of 21-gene assay for node-positive early breast cancer.

Masucci L, Torres S, Eisen A, Trudeau M, Tyono I, Saunders H, Chan KW, Isaranuwatchai W.

Curr Oncol. 2019 Oct;26(5):307-318. doi: 10.3747/co.26.4769. Epub 2019 Oct 1.


Temporal Trends in the Characteristics, Management and Outcomes of Patients With Acute Coronary Syndrome According to Their Killip Class.

Itzahki Ben Zadok O, Ben-Gal T, Abelow A, Shechter A, Zusman O, Iakobishvili Z, Cohen T, Shlomo N, Kornowski R, Eisen A.

Am J Cardiol. 2019 Dec 15;124(12):1862-1868. doi: 10.1016/j.amjcard.2019.09.012. Epub 2019 Sep 26.


Comparison of Outcomes in Patients With Acute Coronary Syndrome Presenting With Typical Versus Atypical Symptoms.

Hammer Y, Eisen A, Hasdai D, Goldenberg I, Shlomo N, Cohen T, Beigel R, Kornowski R, Iakobishvili Z.

Am J Cardiol. 2019 Dec 15;124(12):1851-1856. doi: 10.1016/j.amjcard.2019.09.007. Epub 2019 Sep 26.


Health outcomes, utility and costs of returning incidental results from genomic sequencing in a Canadian cancer population: protocol for a mixed-methods randomised controlled trial.

Shickh S, Clausen M, Mighton C, Gutierrez Salazar M, Zakoor KR, Kodida R, Reble E, Elser C, Eisen A, Panchal S, Aronson M, Graham T, Armel SR, Morel CF, Fattouh R, Glogowski E, Schrader KA, Hamilton JG, Offit K, Robson M, Carroll JC, Isaranuwatchai W, Kim RH, Lerner-Ellis J, Thorpe KE, Laupacis A, Bombard Y; Incidental Genomics Study Team.

BMJ Open. 2019 Oct 7;9(10):e031092. doi: 10.1136/bmjopen-2019-031092.


Predictors of mammographic density among women with a strong family history of breast cancer.

Moran O, Eisen A, Demsky R, Blackmore K, Knight JA, Panchal S, Ginsburg O, Zbuk K, Yaffe M, Metcalfe KA, Narod SA, Kotsopoulos J.

BMC Cancer. 2019 Jun 26;19(1):631. doi: 10.1186/s12885-019-5855-2.


Amyotrophic lateral sclerosis: Origins traced to impaired balance between neural excitation and inhibition in the neonatal period.

Kiernan MC, Ziemann U, Eisen A.

Muscle Nerve. 2019 Sep;60(3):232-235. doi: 10.1002/mus.26617. Epub 2019 Jul 5. Review.


Performance Measures of Magnetic Resonance Imaging Plus Mammography in the High Risk Ontario Breast Screening Program.

Chiarelli AM, Blackmore KM, Muradali D, Done SJ, Majpruz V, Weerasinghe A, Mirea L, Eisen A, Rabeneck L, Warner E.

J Natl Cancer Inst. 2020 Feb 1;112(2):136-144. doi: 10.1093/jnci/djz079.


Human mastadenovirus in water, sediment, sea surface microlayer, and bivalve mollusk from southern Brazilian beaches.

Gularte JS, Girardi V, Demoliner M, de Souza FG, Filippi M, Eisen AKA, Mena KD, de Quevedo DM, Rigotto C, de Barros MP, Spilki FR.

Mar Pollut Bull. 2019 May;142:335-349. doi: 10.1016/j.marpolbul.2018.12.046. Epub 2019 Apr 3.


A priori prediction of breast tumour response to chemotherapy using quantitative ultrasound imaging and artificial neural networks.

Tadayyon H, Gangeh M, Sannachi L, Trudeau M, Pritchard K, Ghandi S, Eisen A, Look-Hong N, Holloway C, Wright F, Rakovitch E, Vesprini D, Tran WT, Curpen B, Czarnota G.

Oncotarget. 2019 Jun 11;10(39):3910-3923. doi: 10.18632/oncotarget.26996. eCollection 2019 Jun 11.


Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision Making for Early-Stage, Operable Breast Cancer: Update of the ASCO Endorsement of the Cancer Care Ontario Guideline.

Henry NL, Somerfield MR, Abramson VG, Ismaila N, Allison KH, Anders CK, Chingos DT, Eisen A, Ferrari BL, Openshaw TH, Spears PA, Vikas P, Stearns V.

J Clin Oncol. 2019 Aug 1;37(22):1965-1977. doi: 10.1200/JCO.19.00948. Epub 2019 Jun 17.


Practitioner Opinion on Contralateral Prophylactic Mastectomy: How Do We Steer a Patient-Driven Discussion?

Schellenberg AE, Stypulkowski A, Cordeiro E, Holloway CMB, Eisen A, Scheer AS.

Ann Surg Oncol. 2019 Oct;26(11):3489-3494. doi: 10.1245/s10434-019-07432-6. Epub 2019 Jun 11.


Determining the Cancer Diagnostic Interval Using Administrative Health Care Data in a Breast Cancer Cohort.

Groome PA, Webber C, Whitehead M, Moineddin R, Grunfeld E, Eisen A, Gilbert J, Holloway C, Irish JC, Langley H.

JCO Clin Cancer Inform. 2019 May;3:1-10. doi: 10.1200/CCI.18.00131.


Human non-olfactory cognition phase-locked with inhalation.

Perl O, Ravia A, Rubinson M, Eisen A, Soroka T, Mor N, Secundo L, Sobel N.

Nat Hum Behav. 2019 May;3(5):501-512. doi: 10.1038/s41562-019-0556-z. Epub 2019 Mar 11.


Impact of a novel prioritization framework on clinician-led oncology drug submissions.

Keech J, Beca J, Eisen A, Kennedy E, Kim J, Kouroukis CT, Darling G, Ferguson SE, Finelli A, Petrella TM, Perry JR, Chan K, Gavura S.

Curr Oncol. 2019 Apr;26(2):e155-e161. doi: 10.3747/co.26.4501. Epub 2019 Apr 1.


International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation.

Metcalfe K, Eisen A, Senter L, Armel S, Bordeleau L, Meschino WS, Pal T, Lynch HT, Tung NM, Kwong A, Ainsworth P, Karlan B, Moller P, Eng C, Weitzel JN, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.

Br J Cancer. 2019 Jul;121(1):15-21. doi: 10.1038/s41416-019-0446-1. Epub 2019 Apr 11.


Development of patient "profiles" to tailor counseling for incidental genomic sequencing results.

Mighton C, Carlsson L, Clausen M, Casalino S, Shickh S, McCuaig L, Joshi E, Panchal S, Graham T, Aronson M, Piccinin C, Winter-Paquette L, Semotiuk K, Lorentz J, Mancuso T, Ott K, Silberman Y, Elser C, Eisen A, Kim RH, Lerner-Ellis J, Carroll JC, Glogowski E, Schrader K, Bombard Y; Incidental Genomics Study Team.

Eur J Hum Genet. 2019 Jul;27(7):1008-1017. doi: 10.1038/s41431-019-0352-2. Epub 2019 Mar 8.


A response to "Personalised medicine and population health: breast and ovarian cancer".

Antoniou A, Anton-Culver H, Borowsky A, Broeders M, Brooks J, Chiarelli A, Chiquette J, Cuzick J, Delaloge S, Devilee P, Dorval M, Easton D, Eisen A, Eklund M, Eloy L, Esserman L, Garcia-Closas M, Goldgar D, Hall P, Knoppers BM, Kraft P, La Croix A, Madalensky L, Mavaddat N, Mittman N, Nabi H, Olopade O, Pashayan N, Schmidt M, Shieh Y, Simard J, Stover-Fiscallini A, Tice JA, Van't Veer L, Wenger N, Wolfson M, Yau C, Ziv E.

Hum Genet. 2019 Mar;138(3):287-289. doi: 10.1007/s00439-019-01984-z. Epub 2019 Feb 27. No abstract available.


Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers.

Kotsopoulos J, Lubinski J, Lynch HT, Tung N, Armel S, Senter L, Singer CF, Fruscio R, Couch F, Weitzel JN, Karlan B, Foulkes WD, Moller P, Eisen A, Ainsworth P, Neuhausen SL, Olopade O, Sun P, Gronwald J, Narod SA; Hereditary Breast Cancer Clinical Study Group.

Breast Cancer Res Treat. 2019 Jun;175(2):443-449. doi: 10.1007/s10549-019-05162-7. Epub 2019 Feb 12.


Oestrogen receptor status and survival in women with BRCA2-associated breast cancer.

Metcalfe K, Lynch HT, Foulkes WD, Tung N, Olopade OI, Eisen A, Lerner-Ellis J, Snyder C, Kim SJ, Sun P, Narod SA.

Br J Cancer. 2019 Feb;120(4):398-403. doi: 10.1038/s41416-019-0376-y. Epub 2019 Feb 6.


The association between red cell distribution width and clinical outcomes in patients hospitalised due to chest pain.

Topaz G, Yeruchimovich M, Pereg D, Eitan M, Kitay-Cohen Y, Hammer Y, Itzhaki Ben Zadok O, Eisen A.

Acta Cardiol. 2019 Oct;74(5):413-418. doi: 10.1080/00015385.2018.1521055. Epub 2019 Jan 16.


Guideline-Recommended Therapies and Clinical Outcomes According to the Risk for Recurrent Cardiovascular Events After an Acute Coronary Syndrome.

Hammer Y, Iakobishvili Z, Hasdai D, Goldenberg I, Shlomo N, Einhorn M, Bental T, Witberg G, Kornowski R, Eisen A.

J Am Heart Assoc. 2018 Sep 18;7(18):e009885. doi: 10.1161/JAHA.118.009885.


Response to: The Survival Time of 8376 Male Breast Cancer Patients.

Wan BA, Ganesh V, Zhang L, Sousa P, Drost L, Lorentz J, Vesprini D, Lee J, Rakovitch E, Lu FI, Eisen A, Yee C, Lam H, Chow E.

Clin Oncol (R Coll Radiol). 2018 Dec;30(12):818-819. doi: 10.1016/j.clon.2018.08.011. Epub 2018 Sep 10. No abstract available.


Real-world health services utilisation and outcomes after BRCA1 and BRCA2 testing in Ontario, Canada: the What Comes Next Cohort Study protocol.

Dossa F, Cusimano MC, Sutradhar R, Metcalfe K, Little T, Lerner-Ellis J, Eisen A, Meschino WS, Baxter NN.

BMJ Open. 2018 Sep 4;8(9):e025317. doi: 10.1136/bmjopen-2018-025317.


Correction to "A Lattice Model of Charge-Pattern-Dependent Polyampholyte Phase Separation".

Das S, Eisen A, Lin YH, Chan HS.

J Phys Chem B. 2018 Aug 23;122(33):8111. doi: 10.1021/acs.jpcb.8b07367. Epub 2018 Aug 14. No abstract available.


Impact of Self-Reported Family History of Premature Cardiovascular Disease on the Outcomes of Patients Hospitalized for Acute Coronary Syndrome (from the Acute Coronary Syndrome Israel Survey [ACSIS] 2000 to 2013).

Levi A, Chezar-Azerrad C, Hasdai D, Beigel R, Gottlieb S, Eisen A, Shlomo N, Goldenberg I, Landes U, Kornowski R, Iakobishvili Z.

Am J Cardiol. 2018 Sep 15;122(6):917-921. doi: 10.1016/j.amjcard.2018.06.008. Epub 2018 Jun 25.


Early treatment with high-potency statins in patients with acute coronary syndrome-an example of personalized medicine.

Harari E, Eisen A.

J Thorac Dis. 2018 Jun;10(Suppl 17):S2062-S2066. doi: 10.21037/jtd.2018.05.185. No abstract available.


Iatrogenic atrial septal defect post mitral valve in valve implantation.

Chezar-Azerrad C, Assali A, Vaknin-Assa H, Shapira Y, Eisen A, Kornowski R.

Cardiovasc Revasc Med. 2018 Dec;19(8S):82-85. doi: 10.1016/j.carrev.2018.06.010. Epub 2018 Jun 15.


Safety, pharmacokinetics, and preliminary efficacy of E6201 in patients with advanced solid tumours, including melanoma: results of a phase 1 study.

Tibes R, Borad MJ, Dutcus CE, Reyderman L, Feit K, Eisen A, Verbel DA, Von Hoff DD.

Br J Cancer. 2018 Jun;118(12):1580-1585. doi: 10.1038/s41416-018-0099-5. Epub 2018 Jun 5.


Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation.

Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA; Hereditary Ovarian Cancer Clinical Study Group.

Gynecol Oncol. 2018 Jul;150(1):85-91. doi: 10.1016/j.ygyno.2018.05.011. Epub 2018 May 21.


Selection of Optimal Adjuvant Chemotherapy and Targeted Therapy for Early Breast Cancer: ASCO Clinical Practice Guideline Focused Update.

Denduluri N, Chavez-MacGregor M, Telli ML, Eisen A, Graff SL, Hassett MJ, Holloway JN, Hurria A, King TA, Lyman GH, Partridge AH, Somerfield MR, Trudeau ME, Wolff AC, Giordano SH.

J Clin Oncol. 2018 Aug 10;36(23):2433-2443. doi: 10.1200/JCO.2018.78.8604. Epub 2018 May 22.


Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.

Breast Cancer Res Treat. 2018 Sep;171(2):421-426. doi: 10.1007/s10549-018-4822-y. Epub 2018 May 17.


The association between eGFR in the normal or mildly impaired range and incident cadiovascular disease: Age and sex analysis.

Eisen A, Porter A, Hoshen M, Balicer RD, Reges O, Rabi Y, Leibowitz M, Iakobishvili Z, Hasdai D.

Eur J Intern Med. 2018 Aug;54:70-75. doi: 10.1016/j.ejim.2018.05.015.


Gender-Related Differences in Outcomes of Patients with Cardiac Resynchronization Therapy.

Nevzorov R, Porter A, Mostov S, Kazum S, Eisen A, Goldenberg G, Iakobishvili Z, Kusniec J, Golovchiner G, Strasberg B, Haim M.

Isr Med Assoc J. 2018 May;20(5):311-315.


Ataxia-telangiectasia gene (ATM) mutation heterozygosity in breast cancer: a narrative review.

Jerzak KJ, Mancuso T, Eisen A.

Curr Oncol. 2018 Apr;25(2):e176-e180. doi: 10.3747/co.25.3707. Epub 2018 Apr 30. Review.


Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers.

Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.

JAMA Oncol. 2018 Aug 1;4(8):1059-1065. doi: 10.1001/jamaoncol.2018.0211. Erratum in: JAMA Oncol. 2018 Aug 1;4(8):1139.


Evaluation of a decision aid for incidental genomic results, the Genomics ADvISER: protocol for a mixed methods randomised controlled trial.

Shickh S, Clausen M, Mighton C, Casalino S, Joshi E, Glogowski E, Schrader KA, Scheer A, Elser C, Panchal S, Eisen A, Graham T, Aronson M, Semotiuk KM, Winter-Paquette L, Evans M, Lerner-Ellis J, Carroll JC, Hamilton JG, Offit K, Robson M, Thorpe KE, Laupacis A, Bombard Y.

BMJ Open. 2018 Apr 26;8(4):e021876. doi: 10.1136/bmjopen-2018-021876.


Central nervous system in motor neuron disease.

Eisen A.

J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):901-902. doi: 10.1136/jnnp-2018-318186. Epub 2018 Apr 21. No abstract available.


Serum osteoprotegerin levels and mammographic density among high-risk women.

Moran O, Zaman T, Eisen A, Demsky R, Blackmore K, Knight JA, Elser C, Ginsburg O, Zbuk K, Yaffe M, Narod SA, Salmena L, Kotsopoulos J.

Cancer Causes Control. 2018 Jun;29(6):507-517. doi: 10.1007/s10552-018-1035-y. Epub 2018 Apr 20.


Human cerebral evolution and the clinical syndrome of amyotrophic lateral sclerosis.

Henderson RD, Garton FC, Kiernan MC, Turner MR, Eisen A.

J Neurol Neurosurg Psychiatry. 2019 May;90(5):570-575. doi: 10.1136/jnnp-2017-317245. Epub 2018 Apr 17. No abstract available.


Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers.

Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, Olopade O, Zakalik D, Lubinski J, Narod SA, Kotsopoulos J; Hereditary Breast Cancer Clinical Study Group .

Int J Epidemiol. 2018 Jun 1;47(3):987-997. doi: 10.1093/ije/dyy039.


Treatment Outcomes in Male Breast Cancer: A Retrospective Analysis of 161 Patients.

Wan BA, Ganesh V, Zhang L, Sousa P, Drost L, Lorentz J, Vesprini D, Lee J, Rakovitch E, Lu FI, Eisen A, Yee C, Lam H, Chow E.

Clin Oncol (R Coll Radiol). 2018 Jun;30(6):354-365. doi: 10.1016/j.clon.2018.02.026. Epub 2018 Mar 2.


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