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Items: 1 to 50 of 76

1.

Targeting PRPK and TOPK for skin cancer prevention and therapy.

Roh E, Lee MH, Zykova TA, Zhu F, Nadas J, Kim HG, Bae KB, Li Y, Cho YY, Curiel-Lewandrowski C, Einspahr J, Dickinson SE, Bode AM, Dong Z.

Oncogene. 2018 Oct;37(42):5633-5647. doi: 10.1038/s41388-018-0350-9. Epub 2018 Jun 14.

2.

Protein activation mapping of human sun-protected epidermis after an acute dose of erythemic solar simulated light.

Einspahr JG, Curiel-Lewandrowski C, Calvert VS, Stratton SP, Alberts DS, Warneke J, Hu C, Saboda K, Wagener EL, Dickinson S, Dong Z, Bode AM, PetricoinIII EF.

NPJ Precis Oncol. 2017;1. pii: 34. doi: 10.1038/s41698-017-0037-7. Epub 2017 Sep 21.

3.

Effects of Retinoids on Augmentation of Club Cell Secretory Protein.

Chen Y, Vasquez MM, Zhu L, Lizarraga RE, Krutzsch M, Einspahr J, Alberts DS, Di PYP, Martinez FD, Guerra S.

Am J Respir Crit Care Med. 2017 Oct 1;196(7):928-931. doi: 10.1164/rccm.201608-1611LE. No abstract available.

4.

Resatorvid-based Pharmacological Antagonism of Cutaneous TLR4 Blocks UV-induced NF-κB and AP-1 Signaling in Keratinocytes and Mouse Skin.

Janda J, Burkett NB, Blohm-Mangone K, Huang V, Curiel-Lewandrowski C, Alberts DS, Petricoin EF 3rd, Calvert VS, Einspahr J, Dong Z, Bode AM, Wondrak GT, Dickinson SE.

Photochem Photobiol. 2016 Nov;92(6):816-825. doi: 10.1111/php.12659. Epub 2016 Dec 8.

5.

High Proportion of Nuclear Phenotype Identifies Aggressive Cutaneous Squamous Cell Carcinoma.

Glazer ES, Bartels PH, Liang J, Prasad AR, Yozwiak ML, Krutzsch M, Clark C, Kha S, Bartels HG, Einspahr JG, Alberts DS, Krouse RS.

Anal Quant Cytopathol Histpathol. 2015 Oct;37(5):302-9.

PMID:
26856115
6.

Inhibition of Akt Enhances the Chemopreventive Effects of Topical Rapamycin in Mouse Skin.

Dickinson SE, Janda J, Criswell J, Blohm-Mangone K, Olson ER, Liu Z, Barber C, Petricoin EF 3rd, Calvert VS, Einspahr J, Dickinson JE, Stratton SP, Curiel-Lewandrowski C, Saboda K, Hu C, Bode AM, Dong Z, Alberts DS, Timothy Bowden G.

Cancer Prev Res (Phila). 2016 Mar;9(3):215-24. doi: 10.1158/1940-6207.CAPR-15-0419. Epub 2016 Jan 22.

7.

Phase IIB Randomized Study of Topical Difluoromethylornithine and Topical Diclofenac on Sun-Damaged Skin of the Forearm.

Jeter JM, Curiel-Lewandrowski C, Stratton SP, Myrdal PB, Warneke JA, Einspahr JG, Bartels HG, Yozwiak M, Bermudez Y, Hu C, Bartels P, Alberts DS.

Cancer Prev Res (Phila). 2016 Feb;9(2):128-34. doi: 10.1158/1940-6207.CAPR-15-0232. Epub 2015 Dec 28.

8.

Fyn is a redox sensor involved in solar ultraviolet light-induced signal transduction in skin carcinogenesis.

Kim JE, Roh E, Lee MH, Yu DH, Kim DJ, Lim TG, Jung SK, Peng C, Cho YY, Dickinson S, Alberts D, Bowden GT, Einspahr J, Stratton SP, Curiel-Lewandrowski C, Bode AM, Lee KW, Dong Z.

Oncogene. 2016 Aug 4;35(31):4091-101. doi: 10.1038/onc.2015.471. Epub 2015 Dec 21.

9.

Genetic ablation of caspase-7 promotes solar-simulated light-induced mouse skin carcinogenesis: the involvement of keratin-17.

Lee MH, Lim DY, Kim MO, Lee SY, Shin SH, Kim JY, Kim SH, Kim DJ, Jung SK, Yao K, Kundu JK, Lee HS, Lee CJ, Dickinson SE, Alberts D, Bowden GT, Stratton S, Curiel C, Einspahr J, Bode AM, Surh YJ, Cho YY, Dong Z.

Carcinogenesis. 2015 Nov;36(11):1372-80. doi: 10.1093/carcin/bgv110. Epub 2015 Aug 12.

10.

Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin.

Bermudez Y, Stratton SP, Curiel-Lewandrowski C, Warneke J, Hu C, Bowden GT, Dickinson SE, Dong Z, Bode AM, Saboda K, Brooks CA, Petricoin EF 3rd, Hurst CA, Alberts DS, Einspahr JG.

Cancer Prev Res (Phila). 2015 Aug;8(8):720-8. doi: 10.1158/1940-6207.CAPR-14-0407. Epub 2015 Jun 1.

11.

Pilot study on the bioactivity of vitamin d in the skin after oral supplementation.

Curiel-Lewandrowski C, Tang JY, Einspahr JG, Bermudez Y, Hsu CH, Rezaee M, Lee AH, Tangrea J, Parnes HL, Alberts DS, Chow HH.

Cancer Prev Res (Phila). 2015 Jun;8(6):563-9. doi: 10.1158/1940-6207.CAPR-14-0280. Epub 2015 Apr 2.

12.

Randomized, double-blind, placebo-controlled trial of sulindac in individuals at risk for melanoma: evaluation of potential chemopreventive activity.

Curiel-Lewandrowski C, Swetter SM, Einspahr JG, Hsu CH, Nagle R, Sagerman P, Tangrea J, Parnes H, Alberts DS, Chow HH.

Cancer. 2012 Dec 1;118(23):5848-56. doi: 10.1002/cncr.27540. Epub 2012 May 17.

13.

Functional protein pathway activation mapping of the progression of normal skin to squamous cell carcinoma.

Einspahr JG, Calvert V, Alberts DS, Curiel-Lewandrowski C, Warneke J, Krouse R, Stratton SP, Liotta L, Longo C, Pellacani G, Prasad A, Sagerman P, Bermudez Y, Deng J, Bowden GT, Petricoin EF 3rd.

Cancer Prev Res (Phila). 2012 Mar;5(3):403-13. doi: 10.1158/1940-6207.CAPR-11-0427. Erratum in: Cancer Prev Res (Phila). 2012 Aug;5(8):1072. Pellicani, Giovanni [corrected to Pellacani, Giovanni].

14.

Nuclear morphometry identifies a distinct aggressive cellular phenotype in cutaneous squamous cell carcinoma.

Glazer ES, Bartels PH, Prasad AR, Yozwiak ML, Bartels HG, Einspahr JG, Alberts DS, Krouse RS.

Cancer Prev Res (Phila). 2011 Nov;4(11):1770-7. doi: 10.1158/1940-6207.CAPR-10-0404. Epub 2011 Jun 2.

15.

Loss of inositol polyphosphate 5-phosphatase is an early event in development of cutaneous squamous cell carcinoma.

Sekulic A, Kim SY, Hostetter G, Savage S, Einspahr JG, Prasad A, Sagerman P, Curiel-Lewandrowski C, Krouse R, Bowden GT, Warneke J, Alberts DS, Pittelkow MR, DiCaudo D, Nickoloff BJ, Trent JM, Bittner M.

Cancer Prev Res (Phila). 2010 Oct;3(10):1277-83. doi: 10.1158/1940-6207.CAPR-10-0058. Epub 2010 Sep 28.

16.

Chemopreventive efficacy of topical difluoromethylornithine and/or triamcinolone in the treatment of actinic keratoses analyzed by karyometry.

Bartels P, Yozwiak M, Einspahr J, Saboda K, Liu Y, Brooks C, Bartels H, Alberts DS.

Anal Quant Cytol Histol. 2009 Dec;31(6):355-66.

17.

A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.

Stratton SP, Alberts DS, Einspahr JG, Sagerman PM, Warneke JA, Curiel-Lewandrowski C, Myrdal PB, Karlage KL, Nickoloff BJ, Brooks C, Saboda K, Yozwiak ML, Krutzsch MF, Hu C, Lluria-Prevatt M, Dong Z, Bowden GT, Bartels PH.

Cancer Prev Res (Phila). 2010 Feb;3(2):160-9. doi: 10.1158/1940-6207.CAPR-09-0183. Epub 2010 Jan 26.

18.

Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples.

Hostetter G, Kim SY, Savage S, Gooden GC, Barrett M, Zhang J, Alla L, Watanabe A, Einspahr J, Prasad A, Nickoloff BJ, Carpten J, Trent J, Alberts D, Bittner M.

Nucleic Acids Res. 2010 Jan;38(2):e9. doi: 10.1093/nar/gkp881. Epub 2009 Oct 29.

19.

Chemoprevention of human actinic keratoses by topical DL-alpha-tocopherol.

Foote JA, Ranger-Moore JR, Einspahr JG, Saboda K, Kenyon J, Warneke J, Miller RC, Goldman R, Xu MJ, Roe DJ, Alberts DS.

Cancer Prev Res (Phila). 2009 Apr;2(4):394-400. doi: 10.1158/1940-6207.CAPR-08-0210. Epub 2009 Mar 31.

20.

Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer.

Stratton SP, Saboda KL, Myrdal PB, Gupta A, McKenzie NE, Brooks C, Salasche SJ, Warneke JA, Ranger-Moore J, Bozzo PD, Blanchard J, Einspahr JG, Dorr RT, Levine N, Alberts DS.

Nutr Cancer. 2008;60(3):325-30. doi: 10.1080/01635580701840391.

PMID:
18444166
21.

Cross-validation of murine UV signal transduction pathways in human skin.

Einspahr JG, Bowden GT, Alberts DS, McKenzie N, Saboda K, Warneke J, Salasche S, Ranger-Moore J, Curiel-Lewandrowski C, Nagle RB, Nickoloff BJ, Brooks C, Dong Z, Stratton SP.

Photochem Photobiol. 2008 Mar-Apr;84(2):463-76. doi: 10.1111/j.1751-1097.2007.00287.x. Epub 2008 Jan 29.

PMID:
18248498
22.

Karyometry of the colonic mucosa.

Alberts DS, Einspahr JG, Krouse RS, Prasad A, Ranger-Moore J, Hamilton P, Ismail A, Lance P, Goldschmid S, Hess LM, Yozwiak M, Bartels HG, Bartels PH.

Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2704-16.

23.

Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression.

Einspahr JG, Thomas TL, Saboda K, Nickolof BJ, Warneke J, Curiel-Lewandrowski C, Ranger-Moore J, Duckett L, Bangert J, Fruehauf JP, Alberts DS.

Cancer. 2007 Dec 1;110(11):2519-27.

24.

Chromatin phenotype karyometry can predict recurrence in papillary urothelial neoplasms of low malignant potential.

Montironi R, Scarpelli M, Lopez-Beltran A, Mazzucchelli R, Alberts D, Ranger-Moore J, Bartels HG, Hamilton PW, Einspahr J, Bartels PH.

Cell Oncol. 2007;29(1):47-58.

25.

Cyclooxygenase 2 expression in cervical intraepithelial neoplasia and vulvar cancer.

Mitchell A, Newton JM, Brite K, Einspahr J, Ellis M, Davis J, Nuno T, Alberts DS, Garcia F.

J Low Genit Tract Dis. 2007 Apr;11(2):80-5.

PMID:
17415111
26.

Reproducibility and expression of skin biomarkers in sun-damaged skin and actinic keratoses.

Einspahr JG, Xu MJ, Warneke J, Saboda K, Ranger-Moore J, Bozzo P, Duckett L, Goldman R, Lin P, Buckmeier J, Alberts DS.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1841-8. Epub 2006 Oct 4.

27.

Prospects for 3D, nanometer-resolution imaging by confocal STEM.

Einspahr JJ, Voyles PM.

Ultramicroscopy. 2006 Oct-Nov;106(11-12):1041-52. Epub 2006 Jul 5.

PMID:
16916585
28.

Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics.

Einspahr JG, Martinez ME, Jiang R, Hsu CH, Rashid A, Bhattacharrya AK, Ahnen DJ, Jacobs ET, Houlihan PS, Webb CR, Alberts DS, Hamilton SR.

Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1443-50. Erratum in: Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):2016. Rashid, Asif [added].

29.

MGMT promoter methylation and field defect in sporadic colorectal cancer.

Shen L, Kondo Y, Rosner GL, Xiao L, Hernandez NS, Vilaythong J, Houlihan PS, Krouse RS, Prasad AR, Einspahr JG, Buckmeier J, Alberts DS, Hamilton SR, Issa JP.

J Natl Cancer Inst. 2005 Sep 21;97(18):1330-8.

PMID:
16174854
30.

Karyometry in rectal mucosa of patients with previous colorectal adenomas.

Ranger-Moore J, Frank D, Lance P, Alberts D, Yozwiak M, Bartels HG, Einspahr J, Bartels PH.

Anal Quant Cytol Histol. 2005 Jun;27(3):134-42.

PMID:
16121634
31.

Phase III trial of ursodeoxycholic acid to prevent colorectal adenoma recurrence.

Alberts DS, Martínez ME, Hess LM, Einspahr JG, Green SB, Bhattacharyya AK, Guillen J, Krutzsch M, Batta AK, Salen G, Fales L, Koonce K, Parish D, Clouser M, Roe D, Lance P; Phoenix and Tucson Gastroenterologist Networks.

J Natl Cancer Inst. 2005 Jun 1;97(11):846-53.

PMID:
15928305
32.

Karyometric analysis of actinic damage in unexposed and sun-exposed skin and in actinic keratoses in untreated individuals.

Ranger-Moore J, Bartels PH, Bozzo P, Einspahr J, Liu Y, Saboda K, Alberts DS.

Anal Quant Cytol Histol. 2004 Jun;26(3):155-65.

PMID:
15218692
33.

Results of a phase I multiple-dose clinical study of ursodeoxycholic Acid.

Hess LM, Krutzsch MF, Guillen J, Chow HH, Einspahr J, Batta AK, Salen G, Reid ME, Earnest DL, Alberts DS.

Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):861-7.

34.

Safety and efficacy of dose-intensive oral vitamin A in subjects with sun-damaged skin.

Alberts D, Ranger-Moore J, Einspahr J, Saboda K, Bozzo P, Liu Y, Xu XC, Lotan R, Warneke J, Salasche S, Stratton S, Levine N, Goldman R, Islas M, Duckett L, Thompson D, Bartels P, Foote J.

Clin Cancer Res. 2004 Mar 15;10(6):1875-80. Erratum in: Clin Cancer Res. 2004 Aug 15;10(16):5640.

35.

Accuracy of self-reported smoking status among participants in a chemoprevention trial.

Martínez ME, Reid M, Jiang R, Einspahr J, Alberts DS.

Prev Med. 2004 Apr;38(4):492-7.

PMID:
15020184
36.

Karyometry of nuclei from actinic keratosis and squamous cell cancer of the skin.

Ranger-Moore J, Bozzo P, Alberts D, Einspahr J, Liu Y, Thompson D, Stratton S, Stratton MS, Bartels P.

Anal Quant Cytol Histol. 2003 Dec;25(6):353-61.

PMID:
14714302
37.

Reliability and validity of a histologic score as a marker for skin cancer chemoprevention studies.

Bozzo P, Saboda K, Einspahr JG, Ranger-Moore J, Farmer ER, Cockerell CJ, Elder DE, Bangert JL, Hart N, Kramer CB, Alberts DS.

Anal Quant Cytol Histol. 2003 Oct;25(5):285-92.

PMID:
14603727
38.

Skin cancer chemoprevention: strategies to save our skin.

Einspahr JG, Bowden GT, Alberts DS.

Recent Results Cancer Res. 2003;163:151-64; discussion 264-6. Review.

PMID:
12903851
39.

Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival.

Raffel J, Bhattacharyya AK, Gallegos A, Cui H, Einspahr JG, Alberts DS, Powis G.

J Lab Clin Med. 2003 Jul;142(1):46-51.

PMID:
12878985
40.

Association between Cyclooxygenase expression and colorectal adenoma characteristics.

Einspahr JG, Krouse RS, Yochim JM, Danenberg PV, Danenberg KD, Bhattacharyya AK, Martínez ME, Alberts DS.

Cancer Res. 2003 Jul 15;63(14):3891-3.

41.

Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.

Martinez ME, O'Brien TG, Fultz KE, Babbar N, Yerushalmi H, Qu N, Guo Y, Boorman D, Einspahr J, Alberts DS, Gerner EW.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7859-64. Epub 2003 Jun 16.

42.

Variation in cyclooxygenase expression levels within the colorectum.

Wiese FW, Thompson PA, Warneke J, Einspahr J, Alberts DS, Kadlubar FF.

Mol Carcinog. 2003 May;37(1):25-31.

PMID:
12720297
43.

Fecal bile acid concentrations in a subpopulation of the wheat bran fiber colon polyp trial.

Alberts DS, Einspahr JG, Earnest DL, Krutzsch MF, Lin P, Hess LM, Heddens DK, Roe DJ, Martínez ME, Salen G, Batta AK.

Cancer Epidemiol Biomarkers Prev. 2003 Mar;12(3):197-200.

44.

Inhibitory effects of sodium salicylate and acetylsalicylic acid on UVB-induced mouse skin carcinogenesis.

Bair WB 3rd, Hart N, Einspahr J, Liu G, Dong Z, Alberts D, Bowden GT.

Cancer Epidemiol Biomarkers Prev. 2002 Dec;11(12):1645-52.

45.

Statistical analysis of chemopreventive efficacy of vitamin A in sun-exposed, normal skin.

Bartels PH, Ranger-Moore J, Stratton MS, Bozzo P, Einspahr J, Liu Y, Thompson D, Alberts DS.

Anal Quant Cytol Histol. 2002 Aug;24(4):185-97.

PMID:
12199319
46.

Chemoprevention of human skin cancer.

Einspahr JG, Stratton SP, Bowden GT, Alberts DS.

Crit Rev Oncol Hematol. 2002 Mar;41(3):269-85. Review.

PMID:
11880204
47.

Modulation of biologic endpoints by topical difluoromethylornithine (DFMO), in subjects at high-risk for nonmelanoma skin cancer.

Einspahr JG, Nelson MA, Saboda K, Warneke J, Bowden GT, Alberts DS.

Clin Cancer Res. 2002 Jan;8(1):149-55.

48.

Measurement of chemopreventive efficacy in skin biopsies.

Bozzo P, Alberts DS, Vaught L, da Silva VD, Thompson D, Warnecke J, Miller RC, Einspahr J, Bartels PH.

Anal Quant Cytol Histol. 2001 Aug;23(4):300-12.

PMID:
11531145
49.

Ki-ras proto-oncogene mutations in sporadic colorectal adenomas: relationship to histologic and clinical characteristics.

Maltzman T, Knoll K, Martinez ME, Byers T, Stevens BR, Marshall JR, Reid ME, Einspahr J, Hart N, Bhattacharyya AK, Kramer CB, Sampliner R, Alberts DS, Ahnen DJ.

Gastroenterology. 2001 Aug;121(2):302-9.

PMID:
11487539
50.

Effects of piroxicam on prostaglandin E2 levels in rectal mucosa of adenomatous polyp patients: a randomized phase IIb trial.

Calaluce R, Earnest DL, Heddens D, Einspahr JG, Roe D, Bogert CL, Marshall JR, Alberts DS.

Cancer Epidemiol Biomarkers Prev. 2000 Dec;9(12):1287-92.

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