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Items: 28

1.

Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension.

Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B.

Nat Commun. 2020 Mar 4;11(1):1185. doi: 10.1038/s41467-020-14966-x.

2.

Genetic Predisposition to High-Altitude Pulmonary Edema.

Eichstaedt CA, Mairbäurl H, Song J, Benjamin N, Fischer C, Dehnert C, Schommer K, Berger MM, Bärtsch P, Grünig E, Hinderhofer K.

High Alt Med Biol. 2020 Mar;21(1):28-36. doi: 10.1089/ham.2019.0083. Epub 2020 Jan 23.

PMID:
31976756
3.

Mutually reinforcing effects of genetic variants and interferon-β 1a therapy for pulmonary arterial hypertension development in multiple sclerosis patients.

Lerche M, Eichstaedt CA, Hinderhofer K, Grünig E, Tausche K, Ziemssen T, Halank M, Wirtz H, Seyfarth HJ.

Pulm Circ. 2019 Nov 18;9(3):2045894019872192. doi: 10.1177/2045894019872192. eCollection 2019 Jul-Sep.

4.

Multicentre trials on specialised exercise training and rehabilitation are useful in patients with pulmonary hypertension.

Grünig E, Benjamin N, Eichstaedt CA, Peacock AJ; ERS task force on pulmonary hypertension rehabilitation co-authors.

Eur Respir J. 2019 Nov 7;54(5). pii: 1901631. doi: 10.1183/13993003.01631-2019. Print 2019 Nov. No abstract available.

PMID:
31699780
5.

Early treatment with ambrisentan of mildly elevated mean pulmonary arterial pressure associated with systemic sclerosis: a randomized, controlled, double-blind, parallel group study (EDITA study).

Pan Z, Marra AM, Benjamin N, Eichstaedt CA, Blank N, Bossone E, Cittadini A, Coghlan G, Denton CP, Distler O, Egenlauf B, Fischer C, Harutyunova S, Xanthouli P, Lorenz HM, Grünig E.

Arthritis Res Ther. 2019 Oct 26;21(1):217. doi: 10.1186/s13075-019-1981-0.

6.

The role of rehabilitation in patients with pulmonary arterial hypertension.

Eichstaedt CA, Benjamin N, Xanthouli P, Marra AM, Grünig E.

Curr Opin Pulm Med. 2019 Sep;25(5):398-404. doi: 10.1097/MCP.0000000000000609.

PMID:
31365372
7.

The role of rehabilitation in patients with pulmonary arterial hypertension.

Eichstaedt CA, Benjamin N, Xanthouli P, Marra AM, Grünig E.

Curr Opin Pulm Med. 2019 Jul 24. doi: 10.1097/MCP.0000000000000609. [Epub ahead of print]

PMID:
31343490
8.

Right ventricular size and function under riociguat in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension (the RIVER study).

Marra AM, Halank M, Benjamin N, Bossone E, Cittadini A, Eichstaedt CA, Egenlauf B, Harutyunova S, Fischer C, Gall H, Ghofrani HA, Hoeper MM, Lange TJ, Olsson KM, Klose H, Grünig E.

Respir Res. 2018 Dec 19;19(1):258. doi: 10.1186/s12931-018-0957-y.

9.

Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018.

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kuebler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT.

Int J Cardiol. 2018 Dec 1;272S:4-10. doi: 10.1016/j.ijcard.2018.09.070. Epub 2018 Sep 20. Review.

PMID:
30314839
10.

Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention.

Grunig G, Eichstaedt CA, Verweyen J, Durmus N, Saxer S, Krafsur G, Stenmark K, Ulrich S, Grünig E, Pylawka S.

Front Physiol. 2018 Jul 25;9:955. doi: 10.3389/fphys.2018.00955. eCollection 2018.

11.

Reference Ranges and Determinants of Tricuspid Regurgitation Velocity in Healthy Adults Assessed by Two-Dimensional Doppler-Echocardiography.

Marra AM, Naeije R, Ferrara F, Vriz O, Stanziola AA, D'Alto M, D'Andrea A, Carannante L, Eichstaedt CA, Cittadini A, Benjamin N, Grünig E, Bossone E.

Respiration. 2018;96(5):425-433. doi: 10.1159/000490191. Epub 2018 Jul 18.

12.

Evidence of Early-Stage Selection on EPAS1 and GPR126 Genes in Andean High Altitude Populations.

Eichstaedt CA, Pagani L, Antao T, Inchley CE, Cardona A, Mörseburg A, Clemente FJ, Sluckin TJ, Metspalu E, Mitt M, Mägi R, Hudjashov G, Metspalu M, Mormina M, Jacobs GS, Kivisild T.

Sci Rep. 2017 Oct 12;7(1):13042. doi: 10.1038/s41598-017-13382-4.

13.

Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model.

Hoeper MM, Kramer T, Pan Z, Eichstaedt CA, Spiesshoefer J, Benjamin N, Olsson KM, Meyer K, Vizza CD, Vonk-Noordegraaf A, Distler O, Opitz C, Gibbs JSR, Delcroix M, Ghofrani HA, Huscher D, Pittrow D, Rosenkranz S, Grünig E.

Eur Respir J. 2017 Aug 3;50(2). pii: 1700740. doi: 10.1183/13993003.00740-2017. Print 2017 Aug.

14.

First identification of Krüppel-like factor 2 mutation in heritable pulmonary arterial hypertension.

Eichstaedt CA, Song J, Viales RR, Pan Z, Benjamin N, Fischer C, Hoeper MM, Ulrich S, Hinderhofer K, Grünig E.

Clin Sci (Lond). 2017 Apr 25;131(8):689-698. doi: 10.1042/CS20160930. Epub 2017 Feb 10.

PMID:
28188237
15.

Selective sweep on human amylase genes postdates the split with Neanderthals.

Inchley CE, Larbey CD, Shwan NA, Pagani L, Saag L, Antão T, Jacobs G, Hudjashov G, Metspalu E, Mitt M, Eichstaedt CA, Malyarchuk B, Derenko M, Wee J, Abdullah S, Ricaut FX, Mormina M, Mägi R, Villems R, Metspalu M, Jones MK, Armour JA, Kivisild T.

Sci Rep. 2016 Nov 17;6:37198. doi: 10.1038/srep37198.

16.

EIF2AK4 mutation as "second hit" in hereditary pulmonary arterial hypertension.

Eichstaedt CA, Song J, Benjamin N, Harutyunova S, Fischer C, Grünig E, Hinderhofer K.

Respir Res. 2016 Nov 4;17(1):141.

17.

[Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016].

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kübler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT.

Dtsch Med Wochenschr. 2016 Oct;141(S 01):S4-S9. Epub 2016 Oct 19. German.

PMID:
27760444
18.

Genomic analyses inform on migration events during the peopling of Eurasia.

Pagani L, Lawson DJ, Jagoda E, Mörseburg A, Eriksson A, Mitt M, Clemente F, Hudjashov G, DeGiorgio M, Saag L, Wall JD, Cardona A, Mägi R, Wilson Sayres MA, Kaewert S, Inchley C, Scheib CL, Järve M, Karmin M, Jacobs GS, Antao T, Iliescu FM, Kushniarevich A, Ayub Q, Tyler-Smith C, Xue Y, Yunusbayev B, Tambets K, Mallick CB, Saag L, Pocheshkhova E, Andriadze G, Muller C, Westaway MC, Lambert DM, Zoraqi G, Turdikulova S, Dalimova D, Sabitov Z, Sultana GNN, Lachance J, Tishkoff S, Momynaliev K, Isakova J, Damba LD, Gubina M, Nymadawa P, Evseeva I, Atramentova L, Utevska O, Ricaut FX, Brucato N, Sudoyo H, Letellier T, Cox MP, Barashkov NA, Skaro V, Mulahasanovic L, Primorac D, Sahakyan H, Mormina M, Eichstaedt CA, Lichman DV, Abdullah S, Chaubey G, Wee JTS, Mihailov E, Karunas A, Litvinov S, Khusainova R, Ekomasova N, Akhmetova V, Khidiyatova I, Marjanović D, Yepiskoposyan L, Behar DM, Balanovska E, Metspalu A, Derenko M, Malyarchuk B, Voevoda M, Fedorova SA, Osipova LP, Lahr MM, Gerbault P, Leavesley M, Migliano AB, Petraglia M, Balanovsky O, Khusnutdinova EK, Metspalu E, Thomas MG, Manica A, Nielsen R, Villems R, Willerslev E, Kivisild T, Metspalu M.

Nature. 2016 Oct 13;538(7624):238-242. doi: 10.1038/nature19792. Epub 2016 Sep 21.

19.

Identification of genetic defects in pulmonary arterial hypertension by a new gene panel diagnostic tool.

Song J, Eichstaedt CA, Viales RR, Benjamin N, Harutyunova S, Fischer C, Grünig E, Hinderhofer K.

Clin Sci (Lond). 2016 Nov 1;130(22):2043-2052. doi: 10.1042/CS20160531. Epub 2016 Sep 9.

PMID:
27613157
20.

Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.

Machado RD, Southgate L, Eichstaedt CA, Aldred MA, Austin ED, Best DH, Chung WK, Benjamin N, Elliott CG, Eyries M, Fischer C, Gräf S, Hinderhofer K, Humbert M, Keiles SB, Loyd JE, Morrell NW, Newman JH, Soubrier F, Trembath RC, Viales RR, Grünig E.

Hum Mutat. 2015 Dec;36(12):1113-27. doi: 10.1002/humu.22904. Epub 2015 Oct 12. Review.

21.

Positive selection of AS3MT to arsenic water in Andean populations.

Eichstaedt CA, Antao T, Cardona A, Pagani L, Kivisild T, Mormina M.

Mutat Res. 2015 Oct;780:97-102. doi: 10.1016/j.mrfmmm.2015.07.007. Epub 2015 Jul 29.

22.

Mutation in BMPR2 Promoter: A 'Second Hit' for Manifestation of Pulmonary Arterial Hypertension?

Viales RR, Eichstaedt CA, Ehlken N, Fischer C, Lichtblau M, Grünig E, Hinderhofer K.

PLoS One. 2015 Jul 13;10(7):e0133042. doi: 10.1371/journal.pone.0133042. eCollection 2015.

23.

[Pulmonary hypertension: Possible genetic causes and therapeutic options].

Grünig E, Eichstaedt CA, Ehlken N, Mayer E, Klose H.

Herz. 2015 May;40(3):457-68; quiz 469-70. doi: 10.1007/s00059-015-4230-6. German.

PMID:
25963173
24.

Genetic and phenotypic differentiation of an Andean intermediate altitude population.

Eichstaedt CA, Antão T, Cardona A, Pagani L, Kivisild T, Mormina M.

Physiol Rep. 2015 May;3(5). pii: e12376. doi: 10.14814/phy2.12376.

25.

Analysis of full-length mitochondrial DNA D-loop sequences from Macaca fascicularis of different geographical origin reveals novel haplotypes.

Badhan A, Eichstaedt CA, Almond NM, Knapp LA, Rose NJ.

J Med Primatol. 2015 Jun;44(3):125-36. doi: 10.1111/jmp.12163. Epub 2015 Feb 23.

26.

[Epigenetics and genetics of pulmonary arterial hypertension--new insights from the last years].

Kwapiszewska G, Viales RR, Ehlken N, Eichstaedt CA, Riemekasten G, Grünig G, Mäder I, Schröder T, Klose H, Hinderhofer K, Fischer C, Ulrich S, Grünig E, Olschewski A.

Dtsch Med Wochenschr. 2014 Dec;139 Suppl 4:S111-5. doi: 10.1055/s-0034-1387454. Epub 2014 Dec 9. Review. German. No abstract available.

PMID:
25489679
27.

Genome-wide analysis of cold adaptation in indigenous Siberian populations.

Cardona A, Pagani L, Antao T, Lawson DJ, Eichstaedt CA, Yngvadottir B, Shwe MT, Wee J, Romero IG, Raj S, Metspalu M, Villems R, Willerslev E, Tyler-Smith C, Malyarchuk BA, Derenko MV, Kivisild T.

PLoS One. 2014 May 21;9(5):e98076. doi: 10.1371/journal.pone.0098076. eCollection 2014.

28.

The Andean adaptive toolkit to counteract high altitude maladaptation: genome-wide and phenotypic analysis of the Collas.

Eichstaedt CA, Antão T, Pagani L, Cardona A, Kivisild T, Mormina M.

PLoS One. 2014 Mar 31;9(3):e93314. doi: 10.1371/journal.pone.0093314. eCollection 2014.

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