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Items: 45

1.

Effect of combined irradiation and EGFR/Erb-B inhibition with BIBW 2992 on proliferation and tumour cure in cell lines and xenografts.

Gurtner K, Ebert N, Pfitzmann D, Eicheler W, Zips D, Baumann M, Krause M.

Radiat Oncol. 2014 Dec 2;9:261. doi: 10.1186/s13014-014-0261-z.

2.

ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition.

Toulany M, Minjgee M, Saki M, Holler M, Meier F, Eicheler W, Rodemann HP.

Cancer Biol Ther. 2014 Mar 1;15(3):317-28. doi: 10.4161/cbt.27311. Epub 2013 Dec 9.

3.

Simultaneous PLK1 inhibition improves local tumour control after fractionated irradiation.

Krause M, Kummer B, Deparade A, Eicheler W, Pfitzmann D, Yaromina A, Kunz-Schughart LA, Baumann M.

Radiother Oncol. 2013 Sep;108(3):422-8. doi: 10.1016/j.radonc.2013.06.038. Epub 2013 Jul 25.

PMID:
23891096
4.

Combined treatment of the immunoconjugate bivatuzumab mertansine and fractionated irradiation improves local tumour control in vivo.

Gurtner K, Hessel F, Eicheler W, Dörfler A, Zips D, Heider KH, Krause M, Baumann M.

Radiother Oncol. 2012 Mar;102(3):444-9. doi: 10.1016/j.radonc.2011.10.013. Epub 2011 Nov 17.

PMID:
22100655
5.

Cancer stem cells: targets and potential biomarkers for radiotherapy.

Krause M, Yaromina A, Eicheler W, Koch U, Baumann M.

Clin Cancer Res. 2011 Dec 1;17(23):7224-9. doi: 10.1158/1078-0432.CCR-10-2639. Epub 2011 Oct 5.

6.

Residual DNA double strand breaks in perfused but not in unperfused areas determine different radiosensitivity of tumours.

Menegakis A, Eicheler W, Yaromina A, Thames HD, Krause M, Baumann M.

Radiother Oncol. 2011 Jul;100(1):137-44. doi: 10.1016/j.radonc.2011.07.001. Epub 2011 Aug 5.

PMID:
21821302
7.

Diverse effects of combined radiotherapy and EGFR inhibition with antibodies or TK inhibitors on local tumour control and correlation with EGFR gene expression.

Gurtner K, Deuse Y, Bütof R, Schaal K, Eicheler W, Oertel R, Grenman R, Thames H, Yaromina A, Baumann M, Krause M.

Radiother Oncol. 2011 Jun;99(3):323-30. doi: 10.1016/j.radonc.2011.05.035. Epub 2011 Jun 12.

PMID:
21665304
8.

Cellular and tumor radiosensitivity is correlated to epidermal growth factor receptor protein expression level in tumors without EGFR amplification.

Kasten-Pisula U, Saker J, Eicheler W, Krause M, Yaromina A, Meyer-Staeckling S, Scherkl B, Kriegs M, Brandt B, Grénman R, Petersen C, Baumann M, Dikomey E.

Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1181-8. doi: 10.1016/j.ijrobp.2011.02.043. Epub 2011 Apr 20.

PMID:
21514063
9.

Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation.

Toulany M, Schickfluss TA, Eicheler W, Kehlbach R, Schittek B, Rodemann HP.

Breast Cancer Res. 2011 Mar 10;13(2):R28. doi: 10.1186/bcr2845.

10.

Analysis of chemokine and chemokine receptor expression in squamous cell carcinoma of the head and neck (SCCHN) cell lines.

Wolff HA, Rolke D, Rave-Fränk M, Schirmer M, Eicheler W, Doerfler A, Hille A, Hess CF, Matthias C, Rödel RM, Christiansen H.

Radiat Environ Biophys. 2011 Mar;50(1):145-54. doi: 10.1007/s00411-010-0341-x. Epub 2010 Nov 18.

11.

Effect of cetuximab and fractionated irradiation on tumour micro-environment.

Santiago A, Eicheler W, Bussink J, Rijken P, Yaromina A, Beuthien-Baumann B, van der Kogel AJ, Baumann M, Krause M.

Radiother Oncol. 2010 Nov;97(2):322-9. doi: 10.1016/j.radonc.2010.07.007.

PMID:
20667608
12.

Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation.

Yaromina A, Thames H, Zhou X, Hering S, Eicheler W, Dörfler A, Leichtner T, Zips D, Baumann M.

Radiother Oncol. 2010 Jul;96(1):116-22. doi: 10.1016/j.radonc.2010.04.020.

PMID:
20570380
13.

Prediction of clonogenic cell survival curves based on the number of residual DNA double strand breaks measured by gammaH2AX staining.

Menegakis A, Yaromina A, Eicheler W, Dörfler A, Beuthien-Baumann B, Thames HD, Baumann M, Krause M.

Int J Radiat Biol. 2009 Nov;85(11):1032-41. doi: 10.3109/09553000903242149.

PMID:
19895280
14.

Core needle biopsies for determination of the microenvironment in individual tumours for longitudinal radiobiological studies.

Yaromina A, Eckardt A, Zips D, Eicheler W, Schuetze C, Thames H, Baumann M.

Radiother Oncol. 2009 Sep;92(3):460-5. doi: 10.1016/j.radonc.2009.07.008. Epub 2009 Aug 12.

PMID:
19682759
15.

Triple angiokinase inhibition, tumour hypoxia and radiation response of FaDu human squamous cell carcinomas.

Zips D, Le K, Yaromina A, Dörfler A, Eicheler W, Zhou X, Geyer P, Hilberg F, Baumann M.

Radiother Oncol. 2009 Sep;92(3):405-10. doi: 10.1016/j.radonc.2009.04.006. Epub 2009 May 4.

PMID:
19409639
16.

Epidermal growth factor receptor inhibitors for radiotherapy: biological rationale and preclinical results.

Zips D, Krause M, Yaromina A, Dörfler A, Eicheler W, Schütze C, Gurtner K, Baumann M.

J Pharm Pharmacol. 2008 Aug;60(8):1019-28. doi: 10.1211/jpp.60.8.0008. Review.

PMID:
18644194
17.

Experimental evaluation of functional imaging for radiotherapy.

Zips D, Yaromina A, Schütze C, Wüllrich K, Krause M, Krause M, Hessel F, Eicheler W, Dörfler A, Brüchner K, Menegakis A, Zhou X, Bergmann R, van den Hoff J, Beuthien-Baumann B, Baumann M.

Strahlenther Onkol. 2007 Dec;183 Spec No 2:41-2. doi: 10.1007/s00066-007-2016-3. No abstract available.

PMID:
18167009
18.

EGFR-TK inhibition before radiotherapy reduces tumour volume but does not improve local control: differential response of cancer stem cells and nontumourigenic cells?

Krause M, Prager J, Zhou X, Yaromina A, Dörfler A, Eicheler W, Baumann M.

Radiother Oncol. 2007 Jun;83(3):316-25. Epub 2007 May 24.

PMID:
17531334
19.

Combination of EGFR/HER2 tyrosine kinase inhibition by BIBW 2992 and BIBW 2669 with irradiation in FaDu human squamous cell carcinoma.

Schütze C, Dörfler A, Eicheler W, Zips D, Hering S, Solca F, Baumann M, Krause M.

Strahlenther Onkol. 2007 May;183(5):256-64.

PMID:
17497097
20.

Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: the need for a multivariate approach in biomarker studies.

Yaromina A, Zips D, Thames HD, Eicheler W, Krause M, Rosner A, Haase M, Petersen C, Raleigh JA, Quennet V, Walenta S, Mueller-Klieser W, Baumann M.

Radiother Oncol. 2006 Nov;81(2):122-9. Epub 2006 Sep 7.

PMID:
16956683
21.

Low-dose hyperradiosensitivity of human glioblastoma cell lines in vitro does not translate into improved outcome of ultrafractionated radiotherapy in vivo.

Krause M, Wohlfarth J, Georgi B, Pimentel N, Dorner D, Zips D, Eicheler W, Hessel F, Short SC, Joiner MC, Baumann M.

Int J Radiat Biol. 2005 Oct;81(10):751-8.

PMID:
16449082
22.

Kinetics of EGFR expression during fractionated irradiation varies between different human squamous cell carcinoma lines in nude mice.

Eicheler W, Krause M, Hessel F, Zips D, Baumann M.

Radiother Oncol. 2005 Aug;76(2):151-6.

PMID:
16026875
23.

Does heterogeneity of pimonidazole labelling correspond to the heterogeneity of radiation-response of FaDu human squamous cell carcinoma?

Yaromina A, Hölscher T, Eicheler W, Rosner A, Krause M, Hessel F, Petersen C, Thames HD, Baumann M, Zips D.

Radiother Oncol. 2005 Aug;76(2):206-12.

PMID:
16024121
24.

Enhanced susceptibility of irradiated tumor vessels to vascular endothelial growth factor receptor tyrosine kinase inhibition.

Zips D, Eicheler W, Geyer P, Hessel F, Dörfler A, Thames HD, Haberey M, Baumann M.

Cancer Res. 2005 Jun 15;65(12):5374-9.

25.

Experimental study on different combination schedules of VEGF-receptor inhibitor PTK787/ZK222584 and fractionated irradiation.

Zips D, Krause M, Hessel F, Westphal J, Brüchner K, Eicheler W, Dörfler A, Grenman R, Petersen C, Haberey M, Baumann M.

Anticancer Res. 2003 Sep-Oct;23(5A):3869-76.

PMID:
14666690
26.
27.

Proliferation and micromilieu during fractionated irradiation of human FaDu squamous cell carcinoma in nude mice.

Petersen C, Eicheler W, Frömmel A, Krause M, Balschukat S, Zips D, Baumann M.

Int J Radiat Biol. 2003 Jul;79(7):469-77.

PMID:
14530154
28.

Wild-type sequence of TP53, intron 7.

Eicheler W, Baumann M.

Radiat Res. 2001 Apr;155(4):641. No abstract available.

PMID:
12931731
29.
30.

COX-2 expression in rectal carcinoma: immunohistochemical pattern and clinical outcome.

Petersen S, Haroske G, Hellmich G, Ludwig K, Petersen C, Eicheler W.

Anticancer Res. 2002 Mar-Apr;22(2B):1225-30.

PMID:
12168930
31.

Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection.

Eicheler W, Zips D, Dörfler A, Grénman R, Baumann M.

J Histochem Cytochem. 2002 Feb;50(2):197-204.

PMID:
11799138
32.

Impact of the tumour bed effect on microenvironment, radiobiological hypoxia and the outcome of fractionated radiotherapy of human FaDu squamous-cell carcinoma growing in the nude mouse.

Zips D, Eicheler W, Brüchner K, Jackisch T, Geyer P, Petersen C, van der Kogel AJ, Baumann M.

Int J Radiat Biol. 2001 Dec;77(12):1185-93.

PMID:
11747543
33.

Repopulation of FaDu human squamous cell carcinoma during fractionated radiotherapy correlates with reoxygenation.

Petersen C, Zips D, Krause M, Schöne K, Eicheler W, Hoinkis C, Thames HD, Baumann M.

Int J Radiat Oncol Biol Phys. 2001 Oct 1;51(2):483-93.

PMID:
11567825
34.

Radiobiological hypoxia, oxygen tension, interstitial fluid pressure and relative viable tumour area in two human squamous cell carcinomas in nude mice during fractionated radiotherapy.

Baumann M, Appold S, Zimmer J, Scharf M, Beuthien-Baumann B, Dubben HH, Enghardt W, Schreiber A, Eicheler W, Petersen C.

Acta Oncol. 2001;40(4):519-28.

PMID:
11504313
35.

Impact of preirradiation of the tumour bed on cell production rate and cell loss of human FaDu squamous cell carcinoma growing in nude mice.

Petersen C, Eicheler W, Baisch H, Zips D, Baumann M.

Int J Radiat Biol. 1999 Oct;75(10):1293-7.

PMID:
10549606
36.

5 alpha-reductase activity in the human hair follicle concentrates in the dermal papilla.

Eicheler W, Happle R, Hoffmann R.

Arch Dermatol Res. 1998 Mar;290(3):126-32.

PMID:
9558487
38.

Interleukin-1beta-induced inhibition of hair growth in vitro is mediated by cyclic AMP.

Hoffmann R, Eicheler W, Wenzel E, Happle R.

J Invest Dermatol. 1997 Jan;108(1):40-2.

39.

Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata.

Hoffmann R, Eicheler W, Huth A, Wenzel E, Happle R.

Arch Dermatol Res. 1996 Mar;288(3):153-6.

PMID:
8967784
40.

Immunocytochemical evidence for differential subcellular localization of 5 alpha-reductase isoenzymes in human tissues.

Aumüller G, Eicheler W, Renneberg H, Adermann K, Vilja P, Forssmann WG.

Acta Anat (Basel). 1996;156(4):241-52.

PMID:
9078395
41.

Immunohistochemical evidence for differential distribution of 5 alpha-reductase isoenzymes in human skin.

Eicheler W, Dreher M, Hoffmann R, Happle R, Aumüller G.

Br J Dermatol. 1995 Sep;133(3):371-6.

PMID:
8546990
42.

Distribution of rat hepatic steroid 5 alpha-reductase 1 as shown by immunohistochemistry.

Eicheler W, Seitz J, Steinhoff M, Forssmann WG, Adermann K, Aumüller G.

Exp Clin Endocrinol Diabetes. 1995;103(2):105-12.

PMID:
7553073
43.

Hormonally induced changes in apocrine secretion of transglutaminase in the rat dorsal prostate and coagulating gland.

Steinhoff M, Eicheler W, Holterhus PM, Rausch U, Seitz J, Aumüller G.

Eur J Cell Biol. 1994 Oct;65(1):49-59.

PMID:
7889995
44.

Immunocytochemical localization of human 5 alpha-reductase 2 with polyclonal antibodies in androgen target and non-target human tissues.

Eicheler W, Tuohimaa P, Vilja P, Adermann K, Forssmann WG, Aumüller G.

J Histochem Cytochem. 1994 May;42(5):667-75.

PMID:
8157936
45.

[Current aspects on morphology and functions of the prostate].

Aumüller G, Goebel HW, Bacher M, Eicheler W, Rausch U.

Verh Dtsch Ges Pathol. 1993;77:1-18. Review. German.

PMID:
7511262

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