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Items: 1 to 50 of 265

1.

Correction: Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration.

Zhang W, Muck-Hausl M, Wang J, Sun C, Gebbing M, Miskey C, Ivics Z, Izsvak Z, Ehrhardt A.

PLoS One. 2020 Feb 4;15(2):e0228902. doi: 10.1371/journal.pone.0228902. eCollection 2020.

2.

Correction: Hybrid Adeno-Associated Viral Vectors Utilizing Transposase-Mediated Somatic Integration for Stable Transgene Expression in Human Cells.

Zhang W, Solanki M, Müther N, Ebel M, Wang J, Sun C, Izsvak Z, Ehrhardt A.

PLoS One. 2020 Jan 30;15(1):e0228707. doi: 10.1371/journal.pone.0228707. eCollection 2020.

3.

Cold atmospheric plasma as antiviral therapy - effect on human herpes simplex virus type 1.

Bunz O, Mese K, Funk C, Wulf M, Bailer SM, Piwowarczyk A, Ehrhardt A.

J Gen Virol. 2020 Jan 21. doi: 10.1099/jgv.0.001382. [Epub ahead of print]

PMID:
31961788
4.

State-of-the-art human adenovirus vectorology for therapeutic approaches.

Gao J, Mese K, Bunz O, Ehrhardt A.

FEBS Lett. 2019 Dec;593(24):3609-3622. doi: 10.1002/1873-3468.13691. Epub 2019 Dec 9. Review.

PMID:
31758807
5.

Cystic fibrosis precision therapeutics: Emerging considerations.

Joshi D, Ehrhardt A, Hong JS, Sorscher EJ.

Pediatr Pulmonol. 2019 Nov;54 Suppl 3:S13-S17. doi: 10.1002/ppul.24547. Review.

PMID:
31715091
6.

Engaging Adolescents With Sexual Health Messaging: A Qualitative Analysis.

Chernick LS, Berrigan M, Gonzalez A, Konja A, Stockwell MS, Ehrhardt A, Bakken S, Westhoff CL, Santelli J, Dayan PS.

J Adolesc Health. 2019 Nov;65(5):660-666. doi: 10.1016/j.jadohealth.2019.05.029. Epub 2019 Sep 6.

PMID:
31495641
7.

Enhanced Tropism of Species B1 Adenoviral-Based Vectors for Primary Human Airway Epithelial Cells.

Li N, Cooney AL, Zhang W, Ehrhardt A, Sinn PL.

Mol Ther Methods Clin Dev. 2019 Jul 12;14:228-236. doi: 10.1016/j.omtm.2019.07.001. eCollection 2019 Sep 13.

8.

High-Throughput Analysis of Clinical Flow Cytometry Data by Automated Gating.

Lee H, Sun Y, Patti-Diaz L, Hedrick M, Ehrhardt AG.

Bioinform Biol Insights. 2019 Apr 3;13:1177932219838851. doi: 10.1177/1177932219838851. eCollection 2019.

9.

Viral Vector-Based Delivery of CRISPR/Cas9 and Donor DNA for Homology-Directed Repair in an In Vitro Model for Canine Hemophilia B.

Gao J, Bergmann T, Zhang W, Schiwon M, Ehrke-Schulz E, Ehrhardt A.

Mol Ther Nucleic Acids. 2019 Mar 1;14:364-376. doi: 10.1016/j.omtn.2018.12.008. Epub 2018 Dec 20.

10.

In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.

Wang H, Georgakopoulou A, Psatha N, Li C, Capsali C, Samal HB, Anagnostopoulos A, Ehrhardt A, Izsvák Z, Papayannopoulou T, Yannaki E, Lieber A.

J Clin Invest. 2019 Feb 1;129(2):598-615. doi: 10.1172/JCI122836. Epub 2018 Dec 18.

11.

Effect of cold atmospheric plasma (CAP) on human adenoviruses is adenovirus type-dependent.

Bunz O, Mese K, Zhang W, Piwowarczyk A, Ehrhardt A.

PLoS One. 2018 Oct 26;13(10):e0202352. doi: 10.1371/journal.pone.0202352. eCollection 2018.

12.

Lateral tarsal strip versus lateral tarsal strip with three-snip punctoplasty for managing epiphora in involutional ectropion.

Ehrhardt A, Guechi O, Zaidi M, Sot M, Lhuillier L, Houmad N, Ouamara N, Goetz C, Perone JM.

J Fr Ophtalmol. 2018 Oct;41(8):752-758. doi: 10.1016/j.jfo.2017.12.018. Epub 2018 Sep 11.

PMID:
30217604
13.

One-Vector System for Multiplexed CRISPR/Cas9 against Hepatitis B Virus cccDNA Utilizing High-Capacity Adenoviral Vectors.

Schiwon M, Ehrke-Schulz E, Oswald A, Bergmann T, Michler T, Protzer U, Ehrhardt A.

Mol Ther Nucleic Acids. 2018 Sep 7;12:242-253. doi: 10.1016/j.omtn.2018.05.006. Epub 2018 Jun 7.

14.

Human adenovirus type 17 from species D transduces endothelial cells and human CD46 is involved in cell entry.

Liu J, Boehme P, Zhang W, Fu J, Yumul R, Mese K, Tsoukas R, Solanki M, Kaufmann M, Lu R, Schmidtko A, Stewart AF, Lieber A, Ehrhardt A.

Sci Rep. 2018 Sep 7;8(1):13442. doi: 10.1038/s41598-018-31713-x.

15.

In Vivo Labelling of Adenovirus DNA Identifies Chromatin Anchoring and Biphasic Genome Replication.

Komatsu T, Quentin-Froignant C, Carlon-Andres I, Lagadec F, Rayne F, Ragues J, Kehlenbach RH, Zhang W, Ehrhardt A, Bystricky K, Morin R, Lagarde JM, Gallardo F, Wodrich H.

J Virol. 2018 Aug 29;92(18). pii: e00795-18. doi: 10.1128/JVI.00795-18. Print 2018 Sep 15.

16.

Integrating HDAd5/35++ Vectors as a New Platform for HSC Gene Therapy of Hemoglobinopathies.

Li C, Psatha N, Wang H, Singh M, Samal HB, Zhang W, Ehrhardt A, Izsvák Z, Papayannopoulou T, Lieber A.

Mol Ther Methods Clin Dev. 2018 Feb 15;9:142-152. doi: 10.1016/j.omtm.2018.02.004. eCollection 2018 Jun 15.

17.

Novel Vector Construction Based on Alternative Adenovirus Types via Homologous Recombination.

Zhang W, Fu J, Ehrhardt A.

Hum Gene Ther Methods. 2018 Jun;29(3):124-134. doi: 10.1089/hgtb.2018.044. Epub 2018 Jun 7.

PMID:
29756505
18.

Designer nuclease-mediated gene correction via homology-directed repair in an in vitro model of canine hemophilia B.

Bergmann T, Ehrke-Schulz E, Gao J, Schiwon M, Schildgen V, David S, Schildgen O, Ehrhardt A.

J Gene Med. 2018 May;20(5):e3020. doi: 10.1002/jgm.3020. Epub 2018 May 3.

PMID:
29608237
19.

A Combined In Vivo HSC Transduction/Selection Approach Results in Efficient and Stable Gene Expression in Peripheral Blood Cells in Mice.

Wang H, Richter M, Psatha N, Li C, Kim J, Liu J, Ehrhardt A, Nilsson SK, Cao B, Palmer D, Ng P, Izsvák Z, Haworth KG, Kiem HP, Papayannopoulou T, Lieber A.

Mol Ther Methods Clin Dev. 2017 Nov 10;8:52-64. doi: 10.1016/j.omtm.2017.11.004. eCollection 2018 Mar 16.

20.

CRISPR/Cas9 delivery with one single adenoviral vector devoid of all viral genes.

Ehrke-Schulz E, Schiwon M, Leitner T, Dávid S, Bergmann T, Liu J, Ehrhardt A.

Sci Rep. 2017 Dec 7;7(1):17113. doi: 10.1038/s41598-017-17180-w.

21.

[Practical assessment of DSAEK in the management of endothelial decompensation following penetrating keratoplasty].

Neiter E, Goetz C, Tortuyaux F, Ehrhardt A, Houmad N, Perone JM.

J Fr Ophtalmol. 2017 Dec;40(10):844-852. doi: 10.1016/j.jfo.2017.05.011. Epub 2017 Nov 11. French.

PMID:
29132691
22.

Eliminating the Glass Ceiling in Academic Psychiatry.

Lieberman JA, Ehrhardt AA, Simpson HB, Arbuckle MR, Fyer AJ, Essock SM.

Acad Psychiatry. 2018 Aug;42(4):523-528. doi: 10.1007/s40596-017-0810-5. Epub 2017 Nov 6. No abstract available.

23.

Establishment of the CRISPR/Cas9 System for Targeted Gene Disruption and Gene Tagging.

Ehrke-Schulz E, Schiwon M, Hagedorn C, Ehrhardt A.

Methods Mol Biol. 2017;1654:165-176. doi: 10.1007/978-1-4939-7231-9_11.

PMID:
28986789
24.

From Virus to vector to medicine: Foreword by guest editors.

Kreppel F, Ehrhardt A.

Virus Genes. 2017 Oct;53(5):673-674. doi: 10.1007/s11262-017-1503-6. No abstract available.

PMID:
28921483
25.

Recent Advances in Preclinical Developments Using Adenovirus Hybrid Vectors.

Ehrke-Schulz E, Zhang W, Gao J, Ehrhardt A.

Hum Gene Ther. 2017 Oct;28(10):833-841. doi: 10.1089/hum.2017.140. Review.

PMID:
28854818
26.

Chip-on-the-tip compact flexible endoscopic epifluorescence video-microscope for in-vivo imaging in medicine and biomedical research.

Matz G, Messerschmidt B, Göbel W, Filser S, Betz CS, Kirsch M, Uckermann O, Kunze M, Flämig S, Ehrhardt A, Irion KM, Haack M, Dorostkar MM, Herms J, Gross H.

Biomed Opt Express. 2017 Jun 20;8(7):3329-3342. doi: 10.1364/BOE.8.003329. eCollection 2017 Jul 1.

27.

Getting genetic access to natural adenovirus genomes to explore vector diversity.

Zhang W, Ehrhardt A.

Virus Genes. 2017 Oct;53(5):675-683. doi: 10.1007/s11262-017-1487-2. Epub 2017 Jul 15. Review.

PMID:
28711987
28.

An Engineered Virus Library as a Resource for the Spectrum-wide Exploration of Virus and Vector Diversity.

Zhang W, Fu J, Liu J, Wang H, Schiwon M, Janz S, Schaffarczyk L, von der Goltz L, Ehrke-Schulz E, Dörner J, Solanki M, Boehme P, Bergmann T, Lieber A, Lauber C, Dahl A, Petzold A, Zhang Y, Stewart AF, Ehrhardt A.

Cell Rep. 2017 May 23;19(8):1698-1709. doi: 10.1016/j.celrep.2017.05.008.

29.

Stigma Associated with Classical Congenital Adrenal Hyperplasia in Women's Sexual Lives.

Meyer-Bahlburg HFL, Khuri J, Reyes-Portillo J, Ehrhardt AA, New MI.

Arch Sex Behav. 2018 May;47(4):943-951. doi: 10.1007/s10508-017-1003-8. Epub 2017 May 18.

PMID:
28523454
30.

Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy.

Havunen R, Siurala M, Sorsa S, Grönberg-Vähä-Koskela S, Behr M, Tähtinen S, Santos JM, Karell P, Rusanen J, Nettelbeck DM, Ehrhardt A, Kanerva A, Hemminki A.

Mol Ther Oncolytics. 2016 Dec 31;4:77-86. doi: 10.1016/j.omto.2016.12.004. eCollection 2017 Mar 17.

31.

Dual-labeling with 5-aminolevulinic acid and fluorescein for fluorescence-guided resection of high-grade gliomas: technical note.

Suero Molina E, Wölfer J, Ewelt C, Ehrhardt A, Brokinkel B, Stummer W.

J Neurosurg. 2018 Feb;128(2):399-405. doi: 10.3171/2016.11.JNS161072. Epub 2017 Mar 24.

PMID:
28338432
32.

Gay fathers' motivations for and feelings about surrogacy as a path to parenthood.

Blake L, Carone N, Raffanello E, Slutsky J, Ehrhardt AA, Golombok S.

Hum Reprod. 2017 Apr 1;32(4):860-867. doi: 10.1093/humrep/dex026.

33.

Discovery of phenyl acetamides as potent and selective GPR119 agonists.

Zhu C, Wang L, Zhu Y, Guo ZZ, Liu P, Hu Z, Szewczyk JW, Kang L, Chicchi G, Ehrhardt A, Woods A, Seo T, Woods M, van Heek M, Dingley KH, Pang J, Salituro GM, Powell J, Terebetski JL, Hornak V, Campeau LC, Orr RK, Ujjainwalla F, Miller M, Stamford A, Wood HB, Kowalski T, Nargund RP, Edmondson SD.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1124-1128. doi: 10.1016/j.bmcl.2017.01.091. Epub 2017 Feb 1.

PMID:
28185720
34.

Parenting and the Adjustment of Children Born to Gay Fathers Through Surrogacy.

Golombok S, Blake L, Slutsky J, Raffanello E, Roman GD, Ehrhardt A.

Child Dev. 2018 Jul;89(4):1223-1233. doi: 10.1111/cdev.12728. Epub 2017 Jan 23.

35.

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.

Richter M, Saydaminova K, Yumul R, Krishnan R, Liu J, Nagy EE, Singh M, Izsvák Z, Cattaneo R, Uckert W, Palmer D, Ng P, Haworth KG, Kiem HP, Ehrhardt A, Papayannopoulou T, Lieber A.

Blood. 2016 Nov 3;128(18):2206-2217. Epub 2016 Aug 23. Erratum in: Blood. 2019 Oct 24;134(17):1482.

36.

Robust Ki67 detection in human blood by flow cytometry for clinical studies.

Sun Y, Yang K, Bridal T, Ehrhardt AG.

Bioanalysis. 2016 Dec;8(23):2399-2413. Epub 2016 Nov 3.

37.

Sensitizing ovarian cancer cells to chemotherapy by interfering with pathways that are involved in the formation of cancer stem cells.

Saydaminova K, Strauss R, Xie M, Bartek J, Richter M, van Rensburg R, Drescher C, Ehrhardt A, Ding S, Lieber A.

Cancer Biol Ther. 2016 Oct 2;17(10):1079-1088. Epub 2016 Aug 30.

38.

Kinematical analysis of the V2 ski skating technique: A longitudinal study.

Losnegard T, Myklebust H, Ehrhardt A, Hallén J.

J Sports Sci. 2017 Jun;35(12):1219-1227. doi: 10.1080/02640414.2016.1218036. Epub 2016 Aug 11.

PMID:
27686117
39.

Syndrome-Related Stigma in the General Social Environment as Reported by Women with Classical Congenital Adrenal Hyperplasia.

Meyer-Bahlburg HF, Reyes-Portillo JA, Khuri J, Ehrhardt AA, New MI.

Arch Sex Behav. 2017 Feb;46(2):341-351. doi: 10.1007/s10508-016-0862-8. Epub 2016 Sep 27.

PMID:
27677267
40.

Gay father surrogacy families: relationships with surrogates and egg donors and parental disclosure of children's origins.

Blake L, Carone N, Slutsky J, Raffanello E, Ehrhardt AA, Golombok S.

Fertil Steril. 2016 Nov;106(6):1503-1509. doi: 10.1016/j.fertnstert.2016.08.013. Epub 2016 Aug 24.

41.

A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration.

Boehme P, Zhang W, Solanki M, Ehrke-Schulz E, Ehrhardt A.

Mol Ther Nucleic Acids. 2016 Jul 19;5(7):e337. doi: 10.1038/mtna.2016.44.

42.

Quantification of designer nuclease induced mutation rates: a direct comparison of different methods.

Ehrke-Schulz E, Bergmann T, Schiwon M, Doerner J, Saydaminova K, Lieber A, Ehrhardt A.

Mol Ther Methods Clin Dev. 2016 Jul 6;3:16047. doi: 10.1038/mtm.2016.47. eCollection 2016.

43.

Discovery and development of benzo-[1,2,4]-triazolo-[1,4]-oxazepine GPR142 agonists for the treatment of diabetes.

Wilson JE, Kurukulasuriya R, Sinz C, Lombardo M, Bender K, Parker D, Sherer EC, Costa M, Dingley K, Li X, Mitelman S, Tong S, Bugianesi R, Ehrhardt A, Priest B, Ratliff K, Ujjainwalla F, Nargund R, Hagmann WK, Edmondson S.

Bioorg Med Chem Lett. 2016 Jun 15;26(12):2947-2951. doi: 10.1016/j.bmcl.2016.04.018.

PMID:
27240550
44.

Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5.

Ehrke-Schulz E, Zhang W, Schiwon M, Bergmann T, Solanki M, Liu J, Boehme P, Leitner T, Ehrhardt A.

J Vis Exp. 2016 Jan 28;(107):e52894. doi: 10.3791/52894.

45.

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.

Ehrhardt A, Chung WJ, Pyle LC, Wang W, Nowotarski K, Mulvihill CM, Ramjeesingh M, Hong J, Velu SE, Lewis HA, Atwell S, Aller S, Bear CE, Lukacs GL, Kirk KL, Sorscher EJ.

J Biol Chem. 2016 Jan 22;291(4):1854-65. doi: 10.1074/jbc.M115.704809. Epub 2015 Dec 1.

46.

Adenovirus hexon modifications influence in vitro properties of pseudotyped human adenovirus type 5 vectors.

Solanki M, Zhang W, Jing L, Ehrhardt A.

J Gen Virol. 2016 Jan;97(1):160-168. doi: 10.1099/jgv.0.000328. Epub 2015 Oct 29.

PMID:
26519158
47.

Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras.

Ehrhardt A, Wang B, Yung AC, Wang Y, Kozlowski P, van Breemen C, Schrader JW.

PLoS One. 2015 Oct 30;10(10):e0141493. doi: 10.1371/journal.pone.0141493. eCollection 2015.

48.

[Recurrent migratory knee pain].

Reimer V, Ehrhardt A, Freitag T, Beer M, Schmidt SA.

Radiologe. 2015 Dec;55(12):1111-3. doi: 10.1007/s00117-015-0039-9. German. No abstract available.

PMID:
26508136
49.

Absence of M-Ras modulates social behavior in mice.

Ehrhardt A, Wang B, Leung MJ, Schrader JW.

BMC Neurosci. 2015 Oct 21;16:68. doi: 10.1186/s12868-015-0209-8.

50.

Design of Potent and Orally Active GPR119 Agonists for the Treatment of Type II Diabetes.

Liu P, Hu Z, DuBois BG, Moyes CR, Hunter DN, Zhu C, Kar NF, Zhu Y, Garfunkle J, Kang L, Chicchi G, Ehrhardt A, Woods A, Seo T, Woods M, van Heek M, Dingley KH, Pang J, Salituro GM, Powell J, Terebetski JL, Hornak V, Campeau LC, Lamberson J, Ujjainwalla F, Miller M, Stamford A, Wood HB, Kowalski T, Nargund RP, Edmondson SD.

ACS Med Chem Lett. 2015 Jul 10;6(8):936-41. doi: 10.1021/acsmedchemlett.5b00207. eCollection 2015 Aug 13.

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